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1 Alternative splicing - Wikipedia
https://en.wikipedia.org/wiki/Alternative_splicing
Alternative splicing, or alternative RNA splicing, or differential splicing, is an alternative splicing process during gene expression that allows a single ...
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2 Mechanism of alternative splicing and its regulation (Review)
https://www.spandidos-publications.com/10.3892/br.2014.407
Constitutive splicing is the process of intron removal and exon ligation of the majority of the exons in the order in which they appear in a ...
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3 Alternative transcription exceeds alternative splicing in ... - NCBI
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149493/
Importantly, our results show that the transcript variants from a gene are predominantly generated using alternative transcriptional rather than splicing ...
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4 Alternative Transcript Initiation and Splicing as a ... - PLOS
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0025758
In particular, the production of alternative transcripts leading to multiple isoforms is common for many genes. Different transcription isoforms ...
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5 Alternative Splicing: Our Easy Guide to the Fundamentals
https://bitesizebio.com/10148/what-is-alternative-splicing-and-why-is-it-important/
Therefore, alternative splicing, a type of post-transcriptional modification, is the process by which exons or portions of exons or non-coding ...
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6 Alternative Splicing
https://www.genome.gov/genetics-glossary/Alternative-Splicing
Alternative splicing is a cellular process in which exons from the same gene are joined in different combinations, leading to different, ...
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7 Systematic evaluation of differential splicing tools for RNA-seq ...
https://academic.oup.com/bib/article/21/6/2052/5648232
Differential splicing (DS) enables production of various messenger RNAs (mRNAs), and thereby various protein products, from one gene [1–3]. This ...
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8 Alternative splicing and the evolution of phenotypic novelty
https://royalsocietypublishing.org/doi/10.1098/rstb.2015.0474
Alternative splicing is a process whereby multiple functionally distinct transcripts are encoded from a single gene by the selective removal or ...
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9 Alternative Splicing: A Potential Source of Functional ...
https://www.hindawi.com/journals/ijeb/2012/596274/
Alternative splicing (AS) is a common posttranscriptional process in eukaryotic organisms, by which multiple distinct functional transcripts are produced ...
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10 The Genetic Regulation of Alternative Splicing in Populus ...
https://www.frontiersin.org/articles/10.3389/fpls.2020.00590/full
Alternative splicing (AS) is a mechanism of regulation of the proteome via enabling the production of multiple mRNAs from a single gene. To date ...
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11 spliceR: an R package for classification of alternative splicing ...
https://bmcbioinformatics.biomedcentral.com/articles/10.1186/1471-2105-15-81
RNA-seq data is currently underutilized, in part because it is difficult to predict the functional impact of alternate transcription events.
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12 Regulation of Alternative Splicing Through Coupling with ...
https://www.annualreviews.org/doi/10.1146/annurev-biochem-060614-034242
The coupling of splicing with transcription has an effect on the coordination of multiple alternative splicing events. In genes in which multiple alternative ...
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13 Alternative splicing Definition & Meaning - Merriam-Webster
https://www.merriam-webster.com/medical/alternative%20splicing
The meaning of ALTERNATIVE SPLICING is a mechanism in which different combinations of exons are joined together during the final stages of transcription so ...
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14 The implications of alternative splicing in the ENCODE protein ...
https://www.pnas.org/doi/10.1073/pnas.0700800104
The standard path of protein evolution is usually conceived of as stepwise single base-pair mutations. In contrast alternative splicing typically involves large ...
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15 Alternative Splicing | SpringerLink
https://link.springer.com/10.1007%2F978-3-642-16712-6_427
Alternative splicing describes the process that allows the generation of different forms of mature mRNA (messenger RNA) from the primary gene transcript.
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16 Identifying and Validating Alternative Splicing Events
https://tools.thermofisher.com/content/sfs/brochures/id_altsplicingevents_technote.pdf
GeneChip® Exon Arrays are powerful tools for the discovery and study of mRNA transcript diversity. For the first time, researchers will obtain approximately ...
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17 Alternative Splicing May Not Be the Key to Proteome Complexity
https://www.cell.com/trends/biochemical-sciences/pdf/S0968-0004(16)30118-9.pdf
However, although many thousands of alternatively spliced transcripts are routinely detected in RNA-seq studies, reliable large-scale mass spectrometry-based ...
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18 Robust and annotation-free analysis of alternative splicing ...
https://elifesciences.org/articles/73520
Although alternative splicing is a fundamental and pervasive aspect of gene expression in higher eukaryotes, it is often omitted from ...
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19 Alternative Splicing: Expanding the Landscape of Cancer ...
https://www.mdpi.com/1422-0067/21/23/9032
Alternative splicing (AS) is a critical post-transcriptional regulatory mechanism used by more than 95% of transcribed human genes and responsible for ...
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20 Alternative Splicing, Alternative Promoter and Similar Events ...
http://genome.ucsc.edu/cgi-bin/hgc?hgsid=806822849_YBAeVz7RIdsD1XJN8DN0vy0Ow4PK&c=chr2&l=89096498&r=98140230&o=90098224&t=90107446&g=knownAlt&i=strangeSplice
Cassette Exon (cassetteExon) - Exon is present in some transcripts but not others. These are found by looking for exons that overlap an intron ...
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21 ASTD - Database Commons - National Genomics Data Center
https://ngdc.cncb.ac.cn/databasecommons/database/id/3187
The Alternative Splicing and Transcript Diversity database gives access to a vast collection of alternative transcripts that integrate transcription initiation, ...
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22 The importance of alternative splicing in adaptive evolution
https://onlinelibrary.wiley.com/doi/10.1111/mec.16377
Alternative splicing is a form of transcriptional regulation that enables the production of different mRNA isoforms from a single gene, which ...
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23 The Alternative Splicing and Transcript Diversity database
https://experts.nebraska.edu/en/publications/astd-the-alternative-splicing-and-transcript-diversity-database
The Alternative Splicing and Transcript Diversity database (ASTD) gives access to a vast collection of alternative transcripts that integrate transcription ...
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24 Alternative Splicing Provides a Broad Menu of Proteins for Cells
https://www.the-scientist.com/features/alternative-splicing-provides-a-broad-menu-of-proteins-for-cells-66937
It's now clear that gene transcripts can be constructed in various ways, yet many questions remain about the process. · The discovery of RNA ...
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25 3D Animations - Transcription & Translation: RNA Splicing
https://dnalc.cshl.edu/resources/3d/rna-splicing.html
In some genes the protein-coding sections of the DNA ("exons") are interrupted by non-coding regions ("introns"). RNA splicing removes the introns from pre ...
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26 Alternative start and termination sites of transcription drive ...
https://dash.harvard.edu/bitstream/handle/1/34869028/5778607.pdf?sequence=1
Alternative splicing, alternative promoter usage and alter- native polyadenylation enable the generation of multiple transcript isoforms ...
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27 LESSeq: Local event-based analysis of alternative splicing ...
https://www.biorxiv.org/content/10.1101/841494v1.full
Alternative splicing of precursor-messenger RNA (pre-mRNA) generates multiple transcripts (or isoforms from a single gene locus) that may ...
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28 Alternative pre-mRNA splicing switches modulate gene ...
https://ashpublications.org/blood/article/113/14/3363/24833/Alternative-pre-mRNA-splicing-switches-modulate
The Human Exon 1.0 ST Array can also detect alternative splicing changes within internal regions of transcripts. ... We used this array in ...
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29 Alternative splicing of viral transcripts: the dark side of HBV - Gut
https://gut.bmj.com/content/70/12/2373
Regarding the HBV, numerous reports have described alternative splicing events of the long viral transcript (pregenomic RNA), which also acts as a template ...
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30 Alternative Splicing in Apicomplexan Parasites | mBio
https://journals.asm.org/doi/10.1128/mBio.02866-18
Alternative splicing is a widespread, essential, and complex component of gene regulation. Apicomplexan parasites have long been recognized ...
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31 Genome-Wide Analysis of Alternative Splicing in ...
https://aacrjournals.org/cancerres/article/71/6/2045/572137/Genome-Wide-Analysis-of-Alternative-Splicing-in
Alternative splicing (AS) is key post‐transcriptional mechanism for the generation of protein diversity. It has been estimated that more than 50% of human ...
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32 Alternative splicing - Mikhail Dozmorov
https://mdozmorov.github.io/BIOS668.2018/assets/06_RNA-seq/08_RNA-seq_altsplicing.pdf
Common types of alternative transcript events. Skipped exons and retained introns, in which a single exon or intron is alternatively included or spliced out ...
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33 Alternative Splicing | Encyclopedia MDPI
https://encyclopedia.pub/7047
Alternative splicing (AS) is a critical post-transcriptional regulatory mechanism used by more than 95% of transcribed human genes and responsible for ...
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34 Alternative Splicing of cAMP-specific Phosphodiesterase ...
https://www.jbc.org/article/S0021-9258(18)95540-7/fulltext
Sequencing of the pRPDE39 cDNA shows it to be encoded by the rat PDE4A gene, but to differ from two other PDE4A transcripts, RD1 (pRPDE8; ...
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35 Global Survey of Alternative Splicing in Rice by Direct RNA ...
https://thericejournal.springeropen.com/articles/10.1186/s12284-021-00516-6
Global analysis of miRNAs-targets prediction revealed that alternative spliced transcripts affected miRNAs' targets during development.
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36 Alternative Transcript Initiation and Splicing as a Response to ...
https://www.semanticscholar.org/paper/Alternative-Transcript-Initiation-and-Splicing-as-a-Sprung-Li/19e51af4543dffd006c200f0e73608d16e253f73
49 Citations · DNA Repair Genes: Alternative Transcription and Gene Expression at the Exon Level in Response to the DNA Damaging Agent, Ionizing ...
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37 Eukaryotic pre-mRNA processing | RNA splicing (article)
https://www.khanacademy.org/science/ap-biology/gene-expression-and-regulation/transcription-and-rna-processing/a/eukaryotic-pre-mrna-processing
Through alternative splicing, we (and other eukaryotes) can sneakily encode more different proteins than we have genes in our DNA. In alternative splicing, one ...
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38 Eukaryotic Post-transcriptional Gene Regulation
https://opened.cuny.edu/courseware/module/686/student/?task=2
Splicing is done by spliceosomes, ribonucleoprotein complexes that can recognize the two ends of the intron, cut the transcript at those two points, and bring ...
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39 Alternative Splicing: Definition, Explanation, Examples
https://biologydictionary.net/alternative-splicing/
Alternative splicing is a method cells use to create many proteins from the same strand of DNA. It is also called alternative RNA splicing.
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40 Questions about alternative splicing - Sandwalk
https://sandwalk.blogspot.com/2014/12/questions-about-alternative-splicing.html
Alternative splicing is a mechanism where am intron-containing gene is transcribed and the primary transcript is spliced in two or more ...
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41 Alternative splicing during development of S. commune. (a ...
https://www.researchgate.net/figure/Alternative-splicing-during-development-of-S-commune-a-Primitive-alternative-splicing_fig1_309121218
commune. (a) Primitive alternative splicing events that affect a single transcript. Two alternative transcripts are shown above each other. Thick dark gray bars ...
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42 33. Alternative RNA splicing
https://openoregon.pressbooks.pub/mhccbiology102/chapter/alternative-rna-splicing/
In the 1970s, genes were first observed that exhibited alternative RNA splicing. Alternative RNA splicing is a mechanism that allows different protein products ...
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43 Alternative RNA Splicing: New Approaches for Molecular ...
https://www.intechopen.com/chapters/59510
The alternative splicing plays an important role in the generation of diversity of transcripts its proteins resulting. The aberrant transcripts variants ...
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44 Transcription: Alternate Splicing of Exons
https://www.ndsu.edu/pubweb/~mcclean/plsc731/transcript/transcript5.htm
Alternate splicing occurs at this site to generate the mRNAs that are translated into the shorter proteins. This 22-bp sequence can be considered an extension ...
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45 Gene Splicing Mechanism | Splice Variant Detection
http://www.premierbiosoft.com/tech_notes/gene-splicing.html
Gene splicing leads to the synthesis of alternate proteins that play an important role in the human physiology and disease. Currently, the most efficient ...
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46 Validation of Alternative Transcript Splicing in Chicken Lines ...
https://handle.nal.usda.gov/10113/5454531
Utilizing RNA-seq data, 1,574 candidate genes with alternative splicing were previously identified between two chicken lines that differ in Marek's disease (MD) ...
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47 Alternative Splicing | Profiles RNS
https://profiles.umassmed.edu/profile/125659
A process whereby multiple RNA transcripts are generated from a single gene. Alternative splicing involves the splicing together of other possible sets of ...
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48 Ases :: Alternative Splicing Evolution Server - LCQB
http://www.lcqb.upmc.fr/Ases/documentation
You may simply copy-paste it in a domain-annotation or 3D-structure prediction web server. Transcripts can mutate along the branches by gaining or losing s- ...
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49 Splice variation - Oxford Nanopore Technologies
https://nanoporetech.com/applications/investigation/splice-variation
How do I perform alternative splicing analysis using nanopore sequencing? ... Oxford Nanopore provides three RNA sequencing kits that can be used for gene ...
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50 RNA Splicing- Definition, process, mechanism, types, errors ...
https://microbenotes.com/rna-splicing/
Alternative splicing of pre-mRNA is an essential mechanism to enhance the complexity of gene expression, and it also plays a vital role in ...
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51 The alternative splicing of mRNA transcripts can A. Produce ...
https://www.numerade.com/ask/question/the-alternative-splicing-of-mrna-transcripts-can-a-produce-mrnas-with-one-different-exon-from-the-same-gene-b-produce-mrnas-with-more-or-fewer-exons-from-the-same-gene-c-produce-mrnas-with-c-36401/
VIDEO ANSWER: What is the function of alternative splicing to start with? Alternative slicing is a method of slicing that is used in case of an animal.
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52 RNA Processing, Alternative Splicing, and the Spliceosome ...
https://www.ibiology.org/genetics-and-gene-regulation/alternative-splicing/
Melissa Moore talks about RNA processing to remove non-coding sequences, alternative splicing to produce more than one protein from a single gene, and the ...
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53 alternative splicing – Termwiki, millions of terms defined by people ...
https://en.m.termwiki.com/EN/alternative_splicing_%E2%82%83
A process whereby multiple RNA transcripts are generated from a single gene. Alternative splicing involves the splicing together of other possible sets of ...
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54 Alternative splicing - Wikipedia @ WordDisk
https://www.worddisk.com/wiki/Transcript_variant/
Alternative splicing, or alternative RNA splicing, or differential splicing, ... proteins that bind to cis-acting sites on the primary transcript itself.
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55 Alternative splicing - Academic Dictionaries and Encyclopedias
https://en-academic.com/dic.nsf/enwiki/135905
Alternative splicing (or differential splicing) is a process by which the exons of the RNA produced by transcription of a gene (a primary gene transcript or ...
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56 Differential Splicing Analysis with RNA-Seq: Current ...
https://www.rna-seqblog.com/differential-splicing-analysis-with-rna-seq-current-applications-approaches-limitations/
Differential Splicing Analysis with RNA-Seq: Current Applications, Approaches, & Limitations ... Your browser can't play this video. Learn more ...
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57 Envisagenics, Bristol Myers Squibb Partner to ID Cancer ...
https://www.genomeweb.com/cancer/envisagenics-bristol-myers-squibb-partner-id-cancer-therapy-alternative-splice-targets
SpliceCore consists of the proprietary SpliceTrap, SpliceDuo, and SpliceImpacts2 algorithms, which respectively detect alternative splicing ...
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58 RNA ? 내가 정말 모르고 살았구나.. Alternative splicing
https://jamesjungkuelee.wordpress.com/2014/08/12/rna-%EB%82%B4%EA%B0%80-%EC%A0%95%EB%A7%90-%EB%AA%A8%EB%A5%B4%EA%B3%A0-%EC%82%B4%EC%95%98%EA%B5%AC%EB%82%98-alternative-splicing/
Splicing이란 크로모좀에서 특정 유전자를 있는 그대로 읽어 낸 것을 primary transcript 혹은 precursor mRNA라고 하는데 여기에는 단백질 정보를 ...
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59 PacBio - Sequence with Confidence
https://www.pacb.com/
Discover new genes, transcripts, and alternative splicing events with a complete view of transcript isoform diversity. Learn more. Accelerate your research.
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60 MicroRNAs are deeply linked to the emergence of ... - Science
https://www.science.org/doi/10.1126/sciadv.add9938
We found that alternative splicing was highest in neural tissues, ... The merging resulted in 301,270 transcript models (86,394 if using ...
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61 Disorders of MeCP2 Dosage | NDT - Dove Medical Press
https://www.dovepress.com/rett-syndrome-and-mecp2-duplication-syndrome-disorders-of-mecp2-dosage-peer-reviewed-fulltext-article-NDT
The MECP2 gene contains four exons from which two transcript isoforms ... transcript isoform excludes exon 2 via alternative splicing and is ...
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62 Ensembl genome browser 108
https://www.ensembl.org/index.html

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63 Share Price Information for Genflow Biosci (GENF)
https://www.lse.co.uk/ShareChat.asp?ShareTicker=GENF&share=Genflow-Biosci&thread=39A3CD67-F549-404A-B992-AE5C7F9D3E6D
Alternative splicing results in multiple transcript variants encoding different isoforms. Northeast14. Posts: 1,225. Price: 3.45. No Opinion.
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64 Alternative Splicing: Methods and Protocols
https://books.google.com/books?id=Bxx-EAAAQBAJ&pg=PA81&lpg=PA81&dq=alternative+transcript+splicing&source=bl&ots=qSoYrv68sH&sig=ACfU3U1CEUqePOwQX-1xlJbegbtgnzUAcA&hl=en&sa=X&ved=2ahUKEwiYq6Dy0eP7AhU7lWoFHZRaBM4Q6AF6BQibAhAD
Chapter 6 Analysis of Splicing Regulation by Third-Generation Sequencing Eric Allemand and Fabrice Ango Abstract In Metazoa, the diversity of transcripts ...
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65 The Dictionary of Genomics, Transcriptomics and Proteomics
https://books.google.com/books?id=OEr3CQAAQBAJ&pg=PA53&lpg=PA53&dq=alternative+transcript+splicing&source=bl&ots=QbBl0_CmdZ&sig=ACfU3U1guXWQ_pqgmPfcjTEoZTynY9pnmw&hl=en&sa=X&ved=2ahUKEwiYq6Dy0eP7AhU7lWoFHZRaBM4Q6AF6BQivAhAD
Alternative splicing therefore is a mechanism to produce protein ... or the use of an → alternative transcription start site, → alternative splicing and ...
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66 连环蛋白1(CTNNB1)基因- Gene - MCE
https://www.medchemexpress.cn/gene/1499.html
This gene has 56 transcripts (splice variants), 273 orthologues, 4 paralogues and is ... Alternative splicing results in multiple transcript variants.
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67 Ene Chip Function
https://allesaussergerade.de/ene-chip-function.html
Gene Transcription Activator Protein Mediator Protein RNA Polymerase In ... Gene splicing is a form of genetic engineering where specific genes or gene ...
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68 Brain Transcriptome - Page 109 - Google Books Result
https://books.google.com/books?id=gQZ0AwAAQBAJ&pg=PA109&lpg=PA109&dq=alternative+transcript+splicing&source=bl&ots=930X9G7jVV&sig=ACfU3U0IL2eS-cLUjDdgQf156f2Bf-VWvA&hl=en&sa=X&ved=2ahUKEwiYq6Dy0eP7AhU7lWoFHZRaBM4Q6AF6BQikAhAD
... of the human transcriptome, it has become clear that there is an enormous diversity of alternative transcripts generated by alternative splicing.
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69 Cumulated Index Medicus
https://books.google.com/books?id=SKizMiy3Z0MC&pg=PA2151&lpg=PA2151&dq=alternative+transcript+splicing&source=bl&ots=yvJJ7F6nJ6&sig=ACfU3U0s5T5BK8UgWhD2VZ1S1xQ1GrQJmA&hl=en&sa=X&ved=2ahUKEwiYq6Dy0eP7AhU7lWoFHZRaBM4Q6AF6BQitAhAD
Bernier transcripts which are differentially expressed in some ... The alternative splicing pattern of the tenascin - C pre - mRNA G , et al .
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70 GeneCards - Human Genes | Gene Database | Gene Search
https://www.genecards.org/

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71 Melissa Kagen, "Wandering Games" (MIT Press, 2022) New ...
https://player.fm/series/new-books-in-technology-2421470/melissa-kagen-wandering-games-mit-press-2022
... Gene editing could revive a nearly lost tree" ; the chestnut gene splicing debate in a recent Washington Post article. ... Read the transcript here.
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