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1 Restless legs syndrome - Genetics - MedlinePlus
https://medlineplus.gov/genetics/condition/restless-legs-syndrome/
Restless legs syndrome is a neurological condition that causes an irresistible urge to move the legs. Explore symptoms, inheritance ...
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2 Large genome-wide association study identifies three novel ...
https://www.nature.com/articles/s42003-020-01430-1
RLS is a complex polygenic sensorimotor disorder strongly influenced by lifestyle. This study increases the number of known independent RLS- ...
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3 MEIS1 and Restless Legs Syndrome: A Comprehensive Review
https://www.frontiersin.org/articles/10.3389/fneur.2019.00935/full
MEIS1 region is one of the several loci found to be associated with RLS genetic, which overall explain less than 10% of RLS heritability. The ...
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4 Restless Legs Syndrome: Confirmation of Linkage to ...
https://jamanetwork.com/journals/jamaneurology/fullarticle/788245
Background Genes are involved in the etiology of restless legs syndrome, a common sensorimotor disorder. Objectives To replicate and to further characterize ...
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5 Progress in the genetics of restless legs syndrome
https://academic.oup.com/sleep/article/45/8/zsac136/6604470
Twin and familial aggregation studies have suggested that genetic factors contribute up to 70% of the risk of developing RLS [3, 4]. Linkage ...
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6 Causes of Restless Legs Syndrome (RLS)
https://www.hopkinsmedicine.org/neurology_neurosurgery/centers_clinics/restless-legs-syndrome/what-is-rls/causes.html
RLS is also related to environmental factors and genes. The single largest known environmental factor is low iron levels, which may occur before birth, during ...
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7 Genetics of restless legs syndrome: An update - ScienceDirect
https://www.sciencedirect.com/science/article/pii/S1087079217301545
A major role of genetic factors in the risk of developing restless legs syndrome (RLS) is supported by the high frequency of positive family history of RLS ...
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8 Restless Legs Syndrome
https://rarediseases.org/rare-diseases/restless-legs-syndrome/
In primary RLS, the disorder is often genetic in origin or occurs for unknown reasons (idiopathic). Secondary RLS may occur in association with certain ...
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9 Genetic Association Study of Restless Legs Syndrome in ...
https://www.karger.com/Article/Fulltext/500416
RLS has a well-defined phenotype, increased prevalence in the iron-deficient population and dramatic therapeutic response to dopamine-based ...
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10 Latest Perspectives in Genetic Risk Factors for Restless Legs ...
https://touchneurology.com/movement-disorders/journal-articles/latest-perspectives-in-genetic-risk-factors-for-restless-legs-syndrome/
RLS is usually classified into idiopathic or primary (patients with a possible genetic predisposition and exclusion of other associated ...
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11 Entry - %612853 - RESTLESS LEGS SYNDROME ... - OMIM
https://www.omim.org/entry/612853
Restless legs syndrome (RLS) is a neurologic sleep/wake disorder characterized by uncomfortable and unpleasant sensations in the legs that appear at rest, ...
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12 MEIS1 and BTBD9: genetic association with restless leg ...
https://jmg.bmj.com/content/48/7/462
Restless legs syndrome (RLS) in end stage renal disease (ESRD) is a common form of symptomatic RLS and is associated with increased mortality and reduced ...
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13 An update on the pathophysiology and genetics of restless ...
https://link.springer.com/article/10.1007/s11910-008-0044-8
Genome-wide association studies have recently identified polymorphisms in three genes with no obvious relationship to dopamine that account for ...
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14 Restless Legs Syndrome - 23andMe
https://www.23andme.com/topics/health-predispositions/restless-legs-syndrome/
Genetics does play a role in restless legs syndrome. In addition, people with a family history of RLS have a higher chance of developing RLS themselves.
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15 Identification of novel risk loci for restless legs syndrome in ...
https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(17)30327-7/fulltext
The likelihood of developing symptoms of restless legs syndrome is strongly affected by genetic factors. Family and twin studies have estimated ...
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16 Genome-wide analysis identified novel susceptible genes of ...
https://thejournalofheadacheandpain.biomedcentral.com/articles/10.1186/s10194-022-01409-9
We identified two novel susceptibility loci rs6021854 (in VSTM2L) and rs79823654 (in CCDC141) to be associated with restless legs syndrome in ...
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17 Gene Linked to Restless Leg Syndrome Found - ABC News
https://abcnews.go.com/Health/Healthday/story?id=4507985&page=1
The research, which is in the July 19 issue of the New England Journal of Medicine, found a gene variant that increases the odds of having RLS with periodic ...
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18 A novel autosomal dominant restless legs syndrome locus ...
https://n.neurology.org/content/67/5/900
The authors investigated genetic factors contributing to restless legs syndrome (RLS) by performing a 10-cM genome-wide scan in a large ...
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19 Genome-Wide Association Study Identifies Novel Restless ...
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1002171
Restless legs syndrome (RLS) is a sensorimotor disorder with an age-dependent prevalence of up to 10% in the general population above 65 years ...
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20 Restless legs syndrome is in the genes
http://www.whsc.emory.edu/soundscience/archives/rye.html
“Restless legs is a genetic trait,” says Rye. “Nature loads the gun. Nuture pulls the trigger. Something happens to trigger it. It could be a neuropathy, it ...
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21 Restless legs syndrome study identifies 13 new genetic risk ...
https://www.cam.ac.uk/research/news/restless-legs-syndrome-study-identifies-13-new-genetic-risk-variants
A new study into the genetics underlying restless legs syndrome has identified 13 previously-unknown genetic risk variants, while helping inform ...
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22 Identification of Restless Legs Syndrome Genes by Mutational ...
https://onlinelibrary.wiley.com/doi/full/10.1002/ana.25658
Nine of them (AAGAB, ATP2C1, CNTN4, COL6A6, CRBN, GLO1, NTNG1, STEAP4, VAV3) resided in the vicinity of known restless legs syndrome loci, ...
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23 Researchers Discover Gene Responsible For Restless Legs ...
https://www.sciencedaily.com/releases/2007/07/070719011318.htm
The researchers report a population-attributable risk for RLS of at least 50 percent, meaning that were the gene variant not present, more than ...
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24 restless legs syndrome 6 (postulated), BTBD9-related - FlyBase
https://flybase.org/reports/FBhh0000491.html
In genome-wide association studies (GWAS), the region of the human BTBD9 gene has been associated with restless legs syndrome; subsequent work in humans has ...
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25 Restless Legs Syndrome 6 (RLS6) - MalaCards
https://www.malacards.org/card/restless_legs_syndrome_6
An important gene associated with Restless Legs Syndrome 6 is RLS6 (Restless Legs Syndrome, Susceptibility To, 6). The drugs Dopamine and Iron have been ...
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26 Restless Legs Syndrome (RLS): Causes, Symptoms, Diagnosis
https://my.clevelandclinic.org/health/diseases/9497-restless-legs-syndrome
Restless legs syndrome (RLS) has been found to be a genetic syndrome in some cases, meaning that parents with RLS can pass it down to their ...
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27 Treatment for Restless Legs Syndrome Focuses on Relieving ...
https://newsnetwork.mayoclinic.org/discussion/treatment-for-restless-legs-syndrome-focuses-on-relieving-the-symptoms/
Restless legs syndrome, or RLS, is not always hereditary. But it does run in some families, and several genetic links have been found for RLS.
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28 Restless Legs Syndrome: New Gene Clues - WebMD
https://www.webmd.com/sleep-disorders/news/20070718/restless-legs-syndrome-new-gene-clues
The gene scans show that a certain variation in the BTBD9 gene was associated restless legs syndrome and other periodic limb movements during ...
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29 Causes and Risk Factors of Restless Legs Syndrome
https://www.verywellhealth.com/restless-legs-syndrome-causes-5069908
Secondary RLS occurs from a non-genetic cause and is often related to another medical condition. The most common causes of secondary RLS are:.
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30 Restless Legs Syndrome-associated intronic common variant ...
https://genome.cshlp.org/content/24/4/592.full.html
RLS has a heritability of ∼50% and is a complex genetic disorder. GWAS identified common genetic variants within six risk loci (Winkelmann ...
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31 Is Restless Leg Syndrome Hereditary & What Can I Do?
https://www.usaveinclinics.com/blog/is-restless-leg-syndrome-hereditary/
Genetics: Is RLS hereditary? Restless legs syndrome and genetics appear to be correlated, as close to 50% of people suffering from RLS have ...
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32 Restless legs syndrome - Causes - NHS
https://www.nhs.uk/conditions/restless-legs-syndrome/causes/
In many cases, the exact cause of restless legs syndrome is unknown. When no cause can be found, it's known as idiopathic or primary restless legs syndrome.
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33 Genetic basis for the restless legs syndrome - Ingenta Connect
https://www.ingentaconnect.com/content/10.1691/pn.20180003
It is now clear that RLS has a strong genetic component. Recent studies have identified a number of genes, including variants of PTPRD, MEIS1, ...
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34 A Genetic Risk Factor for Periodic Limb Movements in Sleep
https://www.nejm.org/doi/full/10.1056/NEJMoa072743
The restless legs syndrome (RLS) is a common neurologic disorder characterized by an irresistible urge to move the legs.
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35 Genetics links sleep disturbance with restless legs syndrome ...
https://www.manchester.ac.uk/discover/news/genetics-links-sleep-disturbance-with-restless-legs-syndrome-schizophrenia-and-obesity/
The strongest genetic association for insomnia symptoms fell within a gene previously linked to restless legs syndrome – a nervous system ...
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36 RLS (Didriksen, 2020) – Is Restless Leg Syndrome Genetic?
https://nebula.org/blog/is-restless-leg-syndrome-genetic/
Restless leg syndrome is most likely a combination of genetic and environmental factors. Several genes have been associated with developing the ...
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37 New Susceptibility Genes IDed for Restless Leg Syndrome
https://sleepreviewmag.com/sleep-disorders/movement-disorders/restless-legs-syndrome/susceptibility-genes-rls/
Rouleau and his research team found genes observed to be associated with RLS that were not reported in previous genetic studies. “For instance, PPP3R1, among ...
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38 Medline ® Abstract for Reference 54 of 'Restless legs ...
https://www.uptodate.com/contents/restless-legs-syndrome-and-periodic-limb-movement-disorder-in-children/abstract/54
Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis. AU ...
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39 restless legs syndrome Gene Set
https://maayanlab.cloud/Harmonizome/gene_set/restless+legs+syndrome/GWASdb+SNP-Disease+Associations
restless legs syndrome Gene Set ; Description, A central nervous system disease characterized by throbbing, pulling creeping or other unpleasant sensations in ...
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40 Restless Leg and Periodic Limb Movement Disorder: Genes ...
https://www.geneticlifehacks.com/restless-leg-and-periodic-limb-movement-disorder-genetics-and-solutions/
In 2007, genome-wide studies found that the BTBD9 and MEIS1 genes were linked with an increased risk of both restless leg syndrome and periodic limb movement ...
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41 Susceptible genes of restless legs syndrome in migraine
https://journals.sagepub.com/doi/10.1177/0333102415620907
Restless legs syndrome (RLS) is a disease that is characterized by an imperative urge to move the legs. RLS mostly affects individuals at night ...
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42 Pathophysiology of the Restless Legs Syndrome
https://www.e-jsm.org/journal/view.php?number=30
RLS encompasses an idiopathic form of genetic or unknown origin and symptomatic forms secondary to other medical conditions. Symptomatic forms are associated ...
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43 LAG3/CD4 Genes Variants and the Risk for Restless Legs ...
https://www.mdpi.com/1422-0067/23/23/14795
We found a lack of association between the frequencies of genotypes and allelic variants of the 3 SNVs studied and the risk of RLS, and a weak though ...
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44 How Genes Affect The Risk of Restless Leg Syndrome
https://www.xcode.life/genes-and-sleep/how-does-genetics-affect-the-risk-of-restless-leg-syndrome/
MEIS1 and RLS · Restless Leg Syndrome is a neurologic and sleep-related movement disorder characterized by an irresistible urge to move in the legs, which ...
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45 (PDF) Identification of Restless Legs Syndrome Genes by ...
https://www.researchgate.net/publication/337684562_Identification_of_Restless_Legs_Syndrome_Genes_by_Mutational_Load_Analysis
Nine of them (AAGAB, ATP2C1, CNTN4, COL6A6, CRBN, GLO1, NTNG1, STEAP4, VAV3) resided in the vicinity of known restless legs syndrome loci while five (BBS7, ...
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46 Genetics of Restless Legs Syndrome | 11 | Sha
https://www.taylorfrancis.com/chapters/edit/10.3109/9781420019575-11/genetics-restless-legs-syndrome-shaoqi-rao-juliane-winkelmann-qing-wang
Recent advances in molecular and genetic epidemiological studies of restless legs syndrome (RLS) (MIM 102300) have led to a series of important discoveries.
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47 Restless Legs Syndrome - Baylor College of Medicine
https://www.bcm.edu/healthcare/specialties/neurology/parkinsons-disease-and-movement-disorders/restless-legs-syndrome
Therefore, this RLS is usually "genetic." Often patients do not know that other family members suffer from the same condition because the relatives usually do ...
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48 Genetics of restless legs syndrome: An update. - Europe PMC
https://europepmc.org/article/med/29033051
A major role of genetic factors in the risk of developing restless legs syndrome (RLS) is supported by the high frequency of positive family history of RLS ...
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49 Restless legs in the genes, not the imagination - NBC News
https://www.nbcnews.com/health/health-news/restless-legs-genes-not-imagination-flna1c9460243
A second study in Nature Genetics identified the same gene variation and two others in Germans and Canadians with restless legs syndrome. “This ...
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50 Next Generation Sequencing Based Comprehensive ...
https://www.researchsquare.com/article/rs-451536/v1.pdf
Restless Legs Syndrome (RLS), is a common sensorimotor of sleep ... According to genetic studies, restless legs syndrome is a disease of ...
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51 Clinical and Genetic Description of a Family With a High ...
https://www.mayoclinicproceedings.org/article/S0025-6196(11)60821-5/fulltext
Autosomal dominant restless legs syndrome maps on chromosome 14q. ... Genomewide linkage scan identifies a novel susceptibility locus for restless legs syndrome ...
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52 New Genes Linked to Restless Legs Syndrome
https://piedmonthealthcare.com/new-genes-linked-to-restless-legs-syndrome/
A new study involving roughly 46,000 people with restless legs syndrome turned up 13 new gene variants that appear to raise the risk for the ...
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53 Restless Leg Syndrome? It May Be Your Genes
https://valleysleepcenter.com/restless-leg-syndrome-it-may-be-your-genes/
People with Restless Leg Syndrome (RLS) have real difficulty getting a good night sleep and scientists may be closer to understanding why.
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54 Genetics of Restless Legs Syndrome - Clinical Gate
https://clinicalgate.com/genetics-of-restless-legs-syndrome/
Adequate clinical data strongly indicate that RLS has an important genetic component. However, a crucial step before undertaking any molecular ...
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55 Scientists discover a possible cause for restless legs syndrome
https://www.news24.com/health24/medical/leg/news/scientists-discover-a-possible-cause-for-restless-legs-syndrome-20171023
In a large study, researchers have found gene mutations that may explain the cause of restless legs syndrome.
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56 Restless leg syndrome may have genetic roots - The Boston Globe
http://archive.boston.com/news/nation/articles/2007/07/19/restless_leg_syndrome_may_have_genetic_roots/
ATLANTA -- Scientists have linked certain genes to restless legs syndrome, suggesting the twitching condition described as "jimmy legs" in a "Seinfeld" ...
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57 Restless legs syndrome: An overview of pathophysiology ...
https://www.spandidos-publications.com/10.3892/etm.2021.11108
A total of 13 different genes implicated in RLS have been identified as single nucleotide polymorphisms on chromosomes 6p21.2 (BTBD9), 2p14 ( ...
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58 Restless Legs Syndrome (RLS) - Sleep Foundation
https://www.sleepfoundation.org/restless-legs-syndrome
RLS may have a genetic component. Between 40% and 90% of patients with RLS have at least one first-degree relative (parent, sibling, or child) ...
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59 Restless legs syndrome - The Blood Project
https://www.thebloodproject.com/wp-content/uploads/2022/06/RLS.pdf
Restless legs syndrome (RLS) is a sleep- related sensori- motor disorder with an unclear ... differences in health behaviours, genetic risks, disease.
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60 Restless legs syndrome - Wikipedia
https://en.wikipedia.org/wiki/Restless_legs_syndrome
Restless legs syndrome (RLS), also known as Willis-Ekbom disease (WED), is generally a long-term disorder that causes a strong urge to move one's legs.
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61 Restless Legs Syndrome - Genome Analysis - SelfDecode
https://selfdecode.com/disease/restless-legs-syndrome/
This condition may be associated with UREMIA; DIABETES MELLITUS; and rheumatoid arthritis. Restless Legs Syndrome differs from NOCTURNAL MYOCLONUS SYNDROME in ...
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62 Segregation Analysis of Restless Legs Syndrome - JSTOR
https://www.jstor.org/stable/48506769
that non-genetic causes of RLS may exist and RLS is a com- plex disorder. ... Restless legs syndrome Segregation analysis Blinded diagnosis. Abstract.
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63 Mutant flies confirm genetic link to restless legs syndrome
https://www.discovermagazine.com/planet-earth/mutant-flies-confirm-genetic-link-to-restless-legs-syndrome
Amanda Freeman from the Emory University School of Medicine has engineered the flies so that they have a faulty copy of BTBD9, a gene that has ...
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64 Restless Leg Syndrome Gene Found in Flies | Live Science
https://www.livescience.com/20666-restless-leg-gene-flies.html
A couple in bed with the man struggling with a sleep disorder. ... The mysterious condition restless leg syndrome may have a genetic cause, a new ...
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65 Restless Legs Syndrome & Periodic Limb Movements During ...
https://www.utmedicalcenter.org/medical-care/medical-services/procedures-treatments/restless-legs-syndrome-periodic-limb-movements-during-sleep/
Genetic factors are strong predictors of RLS. First, RLS commonly runs in family, especially when it is severe and starts early in life. DNA changes in five ...
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66 Genome-wide association study of restless legs syndrome ...
https://www.semanticscholar.org/paper/Genome-wide-association-study-of-restless-legs-in-Winkelmann-Schormair/a827fd36e209e23f3fd24edc6a283bba89c7507b
A genome-wide association study found highly significant associations between RLS and intronic variants in the homeobox gene MEIS1, ...
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67 The Molecular Genetics of Restless Legs Syndrome
https://www.sleep.theclinics.com/article/S1556-407X(15)00050-8/pdf
Familial aggregation of restless legs syndrome. (RLS) is well documented,1–4 including Ekbom's5 seminal description of the disorder in which he.
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68 Restless legs syndrome - tellmeGen™
https://www.tellmegen.com/en/results/dna-health-testing/restless-legs-syndrome
The underlying cause is currently unknown. A genetic component has been described as more relevant especially in cases of early onset of symptoms. Research also ...
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69 Restless Leg Syndrome linked to brain genes associated with ...
https://vitamindwiki.com/Restless+Leg+Syndrome+linked+to+brain+genes+associated+with+Vitamin+D+and+Iron+%E2%80%93+Nov+2019
Restless legs syndrome is a common complex disorder with different genetic and environmental risk factors. Here we used human cell lines to ...
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70 A direct interaction between two Restless Legs Syndrome ...
https://papyrus.bib.umontreal.ca/xmlui/handle/1866/23455
In 2007, the frst large scale genome wide association study (GWAS) identifed three genomic regions associated with RLS. MEIS1, BTBD9 and MAP2K5/ ...
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71 Is restless legs syndrome in the genes, not in the head?
https://www.seattletimes.com/nation-world/is-restless-legs-syndrome-in-the-genes-not-in-the-head/
A second study in Nature Genetics identified the same gene variation and two others in Germans and Canadians with restless legs syndrome. “This ...
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72 Restless Legs Syndrome and Other Common Sleep-Related ...
https://journals.lww.com/continuum/fulltext/2020/08000/restless_legs_syndrome_and_other_common.10.aspx
In RLS, a dysfunction in cortical-striatal-thalamic-cortical circuits in genetically vulnerable individuals has been documented. Central iron deficiency is the ...
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73 Grant aids search for Restless Legs Syndrome treatment
https://news.vumc.org/2014/04/03/grant-aids-search-for-restless-legs-syndrome-treatment/
“Changes in iron and dopamine levels in the brain have long been associated with Restless Legs Syndrome and we know from basic biology that ...
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74 Identification of Restless Legs Syndrome Genes by Mutational ...
https://www.synergy-munich.de/publications/2019/tilch.html
Genetic risk loci have been identified but the causatives genes at these loci are largely unknown, so that functional investigation and clinical ...
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75 Two pedigrees with restless legs syndrome in Brazil - SciELO
https://www.scielo.br/j/bjmbr/a/DtJbTpBCQN4LMs4xThLSKgR/?lang=en
Numerous studies have suggested a substantial genetic contribution in the etiology of the primary form of restless legs syndrome (RLS) and periodic leg ...
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76 Association of BTBD9 and MAP2K5/SKOR1 With Restless ...
https://kd.nsfc.gov.cn/paperDownload/ZD6046305.pdf
Keywords: Restless legs syndrome, Genetic risk factors, SNPs, BTBD9, MAP2K5/SKOR1. ... RLS.5,6 Linkage studies identified eight suspected genetic loci.
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77 Screening of novel restless legs syndrome–associated genes ...
https://escholarship.mcgill.ca/downloads/jq085q55w
identified restless legs syndrome (RLS) loci in familial French-Canadian cases. ... a total of 38 cases) were examined for variants in any genes located ...
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78 Restless legs syndrome - SNPedia
https://www.snpedia.com/index.php/Restless_legs_syndrome
The chromosomal regions mentioned in connection with restless legs syndrome include: The MEIS1 gene region on chromosome 2p, including SNPs:.
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79 Studies find genetic clues to restless legs syndrome
https://www2.ljworld.com/news/2007/jul/19/studies_find_genetic_clues_restless_legs_syndrome/
New studies published this week in two top medical journals are being called the first to identify specific genes responsible for restless ...
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80 Restless Legs Syndrome: Detection and Management ... - AAFP
https://www.aafp.org/pubs/afp/issues/2000/0701/p108.html
Primary RLS likely has a genetic origin. Secondary causes of RLS include iron deficiency, neurologic lesions, pregnancy and uremia. RLS also may ...
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81 Restless Leg Syndrome: Triggers, Home Remedies and ...
https://www.youtube.com/watch?v=tEtepQRWWXY
Cleveland Clinic
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82 Restless Leg Syndrome (RLS): What Is It and ... - WinSanTor
https://winsantor.com/restless-leg-syndrome-rls-what-is-it-and-what-are-the-symptoms/
According to Cleveland Clinic, RLS can be genetic, and 92% of patients have a relative with this disorder. Those with a genetic predisposition will usually ...
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83 Gene Linked to Restless Leg Syndrome Found
https://consumer.healthday.com/cognitive-health-information-26/brain-health-news-80/gene-linked-to-restless-leg-syndrome-found-606515.html
The research, which is in the July 19 issue of the New England Journal of Medicine, found a gene variant that increases the odds of having RLS ...
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84 Restless Leg Syndrome (RLS) - DOC Vein Management
https://docveinmanagement.com/new-home/conditions/restless-leg-syndrome-rls/
RLS has been found to be a genetic syndrome in some cases, as parents with RLS can pass it down to their children. In addition, a variety of medical problems, ...
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85 Restless Legs Syndrome: Symptoms, Causes, and Treatments
https://sleepopolis.com/education/restless-leg-syndrome/
Those with a family history of RLS. Because RLS has a strong genetic component, the risk of RLS for those with an affected family member may be ...
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86 Restless legs syndrome - Cenas
https://www.cenas.ch/en/sleep-disorders/restless-legs-syndrome/
Primary RLS means there is no known cause for the condition. In this case, there tends to be a genetic component that induces a lack or imbalance of ...
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87 Understanding Restless Legs Syndrome | Franciscan Health
https://www.franciscanhealth.org/community/blog/restless-leg-syndrome
Restless legs syndrome may have some genetic links since many patients diagnosed with restless legs syndrome report having a first-degree ...
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88 Genetics of Restless Legs Syndrome Expanded - Medindia
https://www.medindia.net/news/genetics-of-restless-legs-syndrome-expanded-173784-1.htm
Thirteen previously-unknown genetic risk variants for developing restless legs syndrome have identified by a study published in Lancet ...
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89 How to Identify and Treat Restless Leg Syndrome | Goodpath
https://www.goodpath.com/learn/restless-leg-syndrome
RLS is related to changes in body function. Two of them are iron deficiency and dopamine. Genetic factors may be involved, and RLS might also be ...
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90 Restless legs syndrome | Psychology Wiki - Fandom
https://psychology.fandom.com/wiki/Restless_legs_syndrome
Restless legs syndrome (RLS) also known as Willis-Ekbom disease (WED) or Wittmaack-Ekbom syndrome, is a neurological disorder characterized by an irresistible ...
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91 What are the causes of Restless Legs Syndrome? - DR.VEGAN
https://drvegan.com/blogs/articles/restless-legs-syndrome-causes-and-how-to-manage-it
Dopamine is a chemical involved in controlling muscle movement and may be responsible for the involuntary leg movements associated with RLS.
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92 The ABCs of RLS: Restless Legs Syndrome - tl;dr pharmacy
https://www.tldrpharmacy.com/content/the-abcs-of-rls-restless-legs-syndrome
From a genetic standpoint, the International RLS Study Group lists the presence of positive family history as a supportive diagnostic criteria.
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93 Restless Leg Syndrome - National Nutrition Articles
https://www.nationalnutrition.ca/articles/health-concerns/restless-leg-syndrome/
Interestingly, RLS is often passed down in families, and over 50% of sufferers report a family member with the same symptoms. The genetic link is especially ...
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