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1 ROLE OF TOLL LIKE RECEPTORS IN RHEUMATOID ... - NCBI
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913446/
TLRs are highly expressed in patients with RA. Increased expression of TLR2 and TLR4 on peripheral blood monocytes from patients with RA has been demonstrated ( ...
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2 Investigation of toll-like receptor (TLR) 4 inhibitor TAK-242 as ...
https://arthritis-research.biomedcentral.com/articles/10.1186/s13075-020-2097-2
We tested whether the TLR4 inhibitor TAK-242 had potential as a remedy for rheumatoid arthritis. Methods. The therapeutic effect of TAK-242 was ...
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3 Direct tissue-sensing reprograms TLR4+ Tfh-like cells ... - Nature
https://www.nature.com/articles/s42003-021-02659-0
TLR4 is a robust tissue-damage sensor implicated in RA initiation and progression. Previous studies focused on TLR4 expression by innate immune ...
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4 IL-29 Enhances LPS/TLR4-Mediated Inflammation in ...
https://www.karger.com/Article/Fulltext/430330
Toll-like receptor 4 (TLR4) plays a crucial role in synovial inflammation and may contribute to the pathogenesis of rheumatology arthritis ...
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5 Linear and Rationally Designed Stapled Peptides Abrogate ...
https://pubs.acs.org/doi/10.1021/acs.jmedchem.9b00061
... of rheumatoid arthritis (RA), where toll-like receptor 4 (TLR4) can ... Relieve Inflammatory Symptoms in Rheumatoid Arthritis Rat Model.
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6 Toll-Like Receptor 4 Is Involved in Inflammatory and Joint ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0023539
In rheumatoid arthritis, a significant proportion of cytokine and chemokine synthesis is attributed to innate immune mechanisms. TLR4 is a ...
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7 VIP down-regulates TLR4 expression and TLR4-mediated ...
https://academic.oup.com/rheumatology/article/45/5/527/1788614
TLR2, TLR4 and MyD88 mRNA expression was increased in RA FLS compared with OA FLS. ... VIP, TLR, Rheumatoid arthritis, Osteoarthritis, Chemokines.
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8 Study of an Anti-TLR4 mAb in Rheumatoid Arthritis
https://clinicaltrials.gov/ct2/show/NCT03241108
Study of an Anti-TLR4 mAb in Rheumatoid Arthritis · Male and female patients · Age >= 18 years old · BMI: < 30 and > 18 · Diagnosis of RA according to 2010 ACR/ ...
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9 Stimulation of TLR2 and TLR4 differentially skews the balance ...
https://www.jci.org/articles/view/32639
TLRs may contribute to the progression of rheumatoid arthritis through recognition of microbial or host-derived ligands found in arthritic joints.
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10 Annals of the Rheumatic Diseases
https://ard.bmj.com/content/68/9/1486
Type I interferons might form the link between Toll-like receptor (TLR) 3/7 and TLR4-mediated synovial inflammation in rheumatoid arthritis (RA). Loading.
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11 High Efficacy Of Toll-Like Receptor 4 Targeting In Murine and ...
https://acrabstracts.org/abstract/high-efficacy-of-toll-like-receptor-4-targeting-in-murine-and-humanized-models-of-rheumatoid-arthritis-in-comparison-with-il-1-and-tnf-inhibitors/
Therapeutic value of TLR4 targeting in RA was revealed by inhibition of TLR4 in the RA synovium-SCID model. Blocking endogenous TLR4 activation in this model ...
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12 Targeting Toll-like Receptor (TLR) Pathways in Inflammatory ...
https://www.mdpi.com/2218-273X/11/9/1291
2. Rheumatoid Arthritis (RA). RA is an autoimmune disease characterized by painful synovial inflammation, joint destruction, systemic inflammation and ...
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13 Association between serum Toll-like receptor 4 and 8-hydroxy-2
https://www.sciencedirect.com/science/article/pii/S1110116420300260
Considering the importance of TLR4 and oxidative stress in RA ... DAS28: disease activity score, RA: rheumatoid arthritis; TLR: toll-like receptor; 8-OHdG: ...
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14 A Novel Drug Combination of Mangiferin and Cinnamic Acid ...
https://www.frontiersin.org/articles/10.3389/fimmu.2022.912933/full
Rheumatoid arthritis (RA), characterized by hyperplasia and inflammation of ... The binding affinity between recombinant TLR4 protein and CA was measured by ...
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15 TLR4 Blockade May Not Treat RA With Inadequate Response ...
https://www.rheumatologyadvisor.com/home/rheumatoid-arthritis-advisor/toll-like-receptor-4-pathway-targeting-not-effective-treatment-in-rheumatoid-arthritis/
The toll-like receptor 4 (TLR4) pathway is not likely a relevant target in treating patients with rheumatoid arthritis (RA) who demonstrate ...
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16 Enhancement of Antibody-Induced Arthritis via Toll-Like ...
https://ajp.amjpathol.org/article/S0002-9440(12)00320-3/pdf
TLR4 stimulation, and was driven by granulocytes, ... characteristics with the human disease rheumatoid arthritis. (RA). However, these experimental models ...
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17 The Inhibitory FcγIIb Receptor Dampens TLR4-Mediated ...
https://journals.aai.org/jimmunol/article/183/7/4509/81761/The-Inhibitory-Fc-IIb-Receptor-Dampens-TLR4
Abstract. Rheumatoid arthritis (RA) is a common autoimmune disease leading to profound disability and premature death. Although a role for FcγRs and TLRs is ...
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18 The role of Toll-like receptors in rheumatoid arthritis
https://link.springer.com/article/10.1007/s11926-009-0051-z
An increasing body of data supports the role of the innate immune system in the pathogenesis of rheumatoid arthritis (RA).
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19 Association of TLR-4 regulatory variants (rs41426344 and ...
https://journals.sagepub.com/doi/10.1177/1721727X16660559
19. Zheng, B, Li, Q, Wei, C. (2010) Lack of association of TLR4 gene Asp299Gly and Thr399Ile polymorphisms with rheumatoid arthritis in Chinese ...
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20 Lack of Association Between TLR4 rs4986790 Polymorphism ...
https://www.liebertpub.com/doi/10.1089/dna.2011.1582
Rheumatoid arthritis (RA) is a chronic inflammatory disease associated with increased cardiovascular (CV) mortality.
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21 IL-29 Enhances LPS/TLR4-Mediated Inflammation in ...
https://agris.fao.org/agris-search/search.do?recordID=DJ20210314349
IL-29 Enhances LPS/TLR4-Mediated Inflammation in Rheumatoid Arthritis [2015]. Donghua Xu; Shushan Yan; Huijuan Wang; Bingjie Gu; et al.
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22 MicroRNA-146a suppresses rheumatoid arthritis fibroblast-like ...
https://www.oncotarget.com/article/24050/text/
Keywords: microRNA-146a; proinflammatory cytokine; fibroblast-like synoviocytes; rheumatoid arthritis; TLR4/NF-κB signaling pathway.
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23 Heat Shock Protein 96 Is Elevated in Rheumatoid Arthritis and ...
https://www.jimmunol.org/content/jimmunol/182/8/4965.full.pdf
with rheumatoid arthritis (RA). Recently, we demonstrated increased TLR2 and TLR4 expression and increased response to microbial TLR2 and TLR4 ligands in ...
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24 Direct tissue sensing reprograms TLR4+ Tfh-like cells ...
https://www.biorxiv.org/content/10.1101/2021.02.19.431679v1.full
CD4+ T cells mediate rheumatoid arthritis (RA) pathogenesis through both ... Here, we identified a TLR4+ follicular helper T (Tfh) cell-like ...
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25 Genotypic analysis of Asp299Gly and Thr399Ile ...
https://ejim.springeropen.com/articles/10.4103/1110-7782.132884
This study was designed to detect the TLR4 (Asp299Gly and Thr399Ile) gene polymorphism in Egyptian patients with rheumatoid arthritis (RA) and ...
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26 Full article: Chymotrypsin attenuates adjuvant-induced arthritis ...
https://www.tandfonline.com/doi/full/10.1080/08923973.2022.2093743?src=
Rheumatoid arthritis (RA) is mainly characterized by synovial hyperplasia, ... Western blotting was used to detect the protein expression of TLR4 and NF-κB ...
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27 The Functional Variant (Asp299gly) of Toll-like Receptor 4 ...
https://www.jrheum.org/content/jrheum/35/4/558.full.pdf
(Asp299Gly) in rheumatoid arthritis (RA). Methods. Peripheral blood mononuclear cells from 28 patients with RA carrying or not carrying the. TLR4 variant ...
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28 A Tenacious Hold on TLR4 | Science Signaling
https://www.science.org/doi/10.1126/scisignal.280ec241
Rheumatoid arthritis is a chronic inflammatory disease that can progress to joint and bone destruction. Inhibitors against Toll-like ...
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29 Rosmanol and Carnosol Synergistically Alleviate Rheumatoid ...
https://mdpi-res.com/d_attachment/molecules/molecules-27-00078/article_deploy/molecules-27-00078-v2.pdf?version=1640586703
Keywords: rheumatoid arthritis; rosmanol; carnosol; Callicarpa longissima; TLR4/NF-κB/MAPK; synergistic effect. 1. Introduction.
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30 MiRNA-506 inhibits rheumatoid arthritis fibroblast-like ...
https://portlandpress.com/bioscirep/article/39/5/BSR20182500/219105/MiRNA-506-inhibits-rheumatoid-arthritis-fibroblast
MiRNA-506 inhibits rheumatoid arthritis fibroblast-like synoviocytes proliferation and induces apoptosis by targetting TLR4. Dan Li;.
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31 Heat shock protein 96 is elevated in rheumatoid arthritis and ...
https://scholars.duke.edu/individual/pub790575
Heat shock protein 96 is elevated in rheumatoid arthritis and activates ... TLR2 and TLR4 ligands in macrophages from the joints of RA.
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32 Investigation of toll-like receptor (TLR) 4 inhibitor TAK-242 as ...
https://d-nb.info/1209266717/34
have inhibitory effect on the pathogenesis of rheumatoid arthritis (RA). We tested whether the TLR4 inhibitor TAK-. 242 had potential as a remedy for ...
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33 MIR-146A and TLR4 gene expression in predicting ...
https://www.ajol.info/index.php/ejbmb/article/view/162219
Disease Activity Score 28 (DAS28) isthe most widely used method for rheumatoid arthritis(RA) disease activity evaluation. However, it may not reflect disease ...
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34 TLR4 Inhibitors - Alzheimer's Drug Discovery Foundation
https://www.alzdiscovery.org/uploads/cognitive_vitality_media/TLR4_Inhibitors.pdf
Elevated TLR4 signaling is implicated in a variety of age-related diseases, ... It failed to show efficacy in a Phase 2 RCT in rheumatoid arthritis.
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35 Linear and Rationally Designed Stapled ... - Europe PMC
https://europepmc.org/article/med/31283217
Linear and Rationally Designed Stapled Peptides Abrogate TLR4 Pathway and Relieve Inflammatory Symptoms in Rheumatoid Arthritis Rat Model. · Author information ...
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36 TLR4 blockade in rheumatoid arthritis disappoints in phase II ...
https://specialty.mims.com/topic/tlr4-blockade-in-rheumatoid-arthritis-disappoints-in-phase-ii-trial
Blocking the toll-like receptor (TLR) 4 pathway with NI-0101, a first-in-class humanized monoclonal antibody, has failed to improve disease ...
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37 Grape seed proanthocyanidin extract ameliorates murine ...
https://www.kjim.org/m/makeCookie.php?url=/m/journal/view.php?number=169698
GSPE treatment reduced the number of TLR4-stained cells in the synovium of ... Rheumatoid arthritis (RA) is a chronic autoimmune disease ...
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38 TlR2 and TlR4 are involved in the treatment of rheumatoid ...
https://www.ingentaconnect.com/content/sp/etm/2020/00000019/00000004/art00074
To investigate the role of asarinin in rheumatoid arthritis (RA), the present study investigated the effect of an asarininmedicated serum on ...
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39 Synergy between 15-lipoxygenase and secreted PLA ... - PNAS
https://www.pnas.org/doi/10.1073/pnas.2005111117
S8C), excluding 15-HpETE as the major contributor to TLR4-dependent gene expression. PLA2 Promotes TLR4-Mediated Arthritis. Synovial fluid from RA patients ...
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40 Bmx tyrosine kinase regulates TLR4-induced IL-6 production ...
https://ashpublications.org/blood/article/111/4/1781/133285/Bmx-tyrosine-kinase-regulates-TLR4-induced-IL-6
Chronic inflammation, as seen in conditions such as rheumatoid arthritis and Crohn disease, is in part driven by discordant production of inflammatory ...
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41 Toll-like Receptor 2 in Autoimmune Inflammation
https://immunenetwork.org/pdf/10.4110/in.2021.21.e18
Expression of Toll-like receptor (TLR) 2, TLR3, TLR4 and TLR7 is increased in rheumatoid arthritis synovium and regulates cytokine production by ...
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42 Communication MESA COMUNICACIONES ORALES I
https://www.reumatologiaclinica.org/en-congresos-xlvi-congreso-nacional-sociedad-espanola-111-sesion-mesa-comunicaciones-orales-i-6080-an-in-silico-in-vitro-72302
Despite TLR4 shares downstream signalling with the known therapeutic target for rheumatoid arthritis, gout, and other autoinflammatory disease, ...
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43 Toll-like receptors in the pathogenesis of autoimmune diseases
https://www.dovepress.com/toll-like-receptors-in-the-pathogenesis-of-autoimmune-diseases-recent--peer-reviewed-fulltext-article-ITT
TLR4 is important in the pathogenesis of RA, as shown by enhanced expression in the synovial tissue of patients with RA and protection from ...
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44 Journal of Clinical Research & Bioethics - Walsh Medical Media
https://www.walshmedicalmedia.com/proceedings/direct-lps-recognition-and-activation-of-cd8-t-cells-via-tlr4-in-patients-with-rheumatoid-arthritis-13121.html
Direct LPS recognition and activation of CD8+ T cells via TLR4 in patients with rheumatoid arthritis. 6th International Conference on Advanced Clinical ...
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45 Lumican is upregulated in osteoarthritis and contributes to TLR4
https://www.oarsijournal.com/article/S1063-4584(19)31248-8/pdf
SF samples from knee meniscectomy, end-stage knee OA, knee rheumatoid arthritis (RA), and carpometacarpal thumb joint (CMC-. I) OA patients were ...
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46 Investigation of the Asp299Gly and Thr399Ile polymorphisms ...
https://dergipark.org.tr/tr/download/article-file/670973
TLR4 gene in Rheumatoid Arthritis. İbrahim Halil Yildirim1, Ramazan Uzen2. 1 Deparment Of Genetics, Faculty of Veterinary, Dicle University, ...
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47 Anti-Arthritic Effect of TLR4 Inhibitor TAK-242 Through the ...
https://www.researchsquare.com/article/rs-156812/v1.pdf
The TLR4 inhibitor TAK-242 has shown potential as a possible treatment for rheumatoid arthritis in an adjuvant- induced arthritis rat model.
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48 Toll-like receptor 4 polymorphisms and susceptibility to ...
https://www.termedia.pl/Journal/-10/pdf-21460-10?filename=Toll%20like%20receptor%204.pdf
search: 'Toll-like receptor-4 or TLR4' and 'autoimmune disease or type 1 diabetes or celiac disease or rheumatoid arthritis or multiple ...
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49 IL-29 Enhances LPS/TLR4-Mediated Inflammation in ... - Gale
https://link.gale.com/apps/doc/A637501398/AONE?u=googlescholar&sid=googleScholar&xid=d71726d5
Toll-like receptor 4 (TLR4) plays a crucial role in synovial inflammation and may contribute to the pathogenesis of rheumatology arthritis (RA).
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50 DAMPening Inflammation by Modulating TLR Signalling
https://www.hindawi.com/journals/mi/2010/672395/
... including rheumatoid arthritis (RA), cancer, and atherosclerosis. TLR activation by DAMPs may initiate positive feedback loops where increasing tissue ...
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51 TLR4 and TLR9 polymorphisms are not associated with either ...
https://www.researchgate.net/publication/351300091_TLR4_and_TLR9_polymorphisms_are_not_associated_with_either_rheumatoid_arthritis_or_systemic_lupus_erythematosus_in_Mexican_patients
However, in rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) ... It has been shown that some TLR4 and TLR9 single nucleotide ...
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52 augmented chemokine production induced by type II collagen ...
https://www.diva-portal.org/smash/get/diva2:1050173/FULLTEXT01.pdf
mediated via TLR4 in rheumatoid arthritis patients. Vivek Anand Manivel1, Azita Sohrabian1 and Johan Rönnelid1,2. 1 Department of Immunology ...
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53 M2000, an Antagonist for Human TLR2 and TLR4
https://irispublishers.com/sjrr/fulltext/m2000-an-antagonist-for-human-tlr2-and-tlr4.ID.000523.php
... TLR4 play a crucial role in immunopathogenesis of autoimmune and inflammatory diseases such as rheumatoid arthritis (RA) and ankylosing ...
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54 Direct tissue-sensing reprograms TLR4 + Tfh-like cells ...
https://novaresearch.unl.pt/en/publications/direct-tissue-sensing-reprograms-tlr4supsup-tfh-like-cells-inflam
CD4+ T cells mediate rheumatoid arthritis (RA) pathogenesis through both antibody-dependent and independent mechanisms.
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55 Cardiotonic Steroids Stimulate Macrophage Inflammatory ...
https://www.ahajournals.org/doi/10.1161/ATVBAHA.117.309444
Subsequently, TLR4 recruited MyD88 adaptor protein for NF-κB activation. ... NF-kappa B in rheumatoid arthritis: a pivotal regulator of ...
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56 A Potent Driving Force behind Rheumatoid Arthritis - J-Stage
https://www.jstage.jst.go.jp/article/jslrt/51/2/51_2_77/_pdf
Keywords: Toll-like receptor, rheumatoid arthritis, pathogen-associated molecular pattern, ... TLR2 and TLR4.14 RA, psoriatic arthritis, Blau syndrome and.
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57 folic acid or methotrexate; Arthritis, Rheumatoid (level 3 Toxicity)
https://www.pharmgkb.org/clinicalAnnotation/1043880467
... for rs4986790 (TLR4); folic acid or methotrexate; Arthritis, Rheumatoid (level 3 ... AA, Patients with the AA genotype and Rheumatoid Arthritis who are ...
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58 Roelofst.pdf - Zurich Open Repository and Archive
https://www.zora.uzh.ch/id/eprint/27420/2/Roelofst.pdf
TLR4 mediated synovial inflammation in rheumatoid arthritis (RA). ... Keywords: Toll-like receptors, rheumatoid arthritis, Type I interferons ...
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59 Mechanism of IL-38 inhibits LPS/TLR4 induced inflammation ...
https://pesquisa.bvsalud.org/portal/resource/pt/wpr-667791
Objective: To investigate the proteins association of IL-38 and TLR4 in rheumatoid arthritis (RA) and its mechanism in RA pathogenesis.
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60 IL-29 Enhances LPS/TLR4-Mediated ... - CyberLeninka
https://cyberleninka.org/article/n/572718.pdf
Interleukin-29 • Nuclear factor-κB • Rheumatology arthritis ... and TLR4 in synovial tissues and fluid from 25 RA patients and 24 controls ...
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61 Meta-analysis demonstrates association between TLR ...
http://www.funpecrp.com.br/gmr/year2013/vol12-1/pdf/gmr1859.pdf
ABSTRACT. We investigated whether Toll-like receptor (TLR) polymorphisms confer susceptibility to rheumatoid arthritis and.
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62 KEGG T01001: 7099
https://www.genome.jp/entry/hsa:7099
hsa05323, Rheumatoid arthritis ... Network. nt06121 TLR signaling (viruses and bacteria) ... N00553, TLR4-IRF3/7 signaling pathway ...
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63 like receptor-4 gene is not associated with rheuma- toid arthritis
https://www.clinexprheumatol.org/article.asp?a=2061
Clinical and Experimental Rheumatology 2003; 21: 340-342. ... like receptor 4 (TLR-4) gene which has ... susceptibility to rheumatoid arthritis.
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64 Doest Rheumatoid Arthritis Take a Toll? - Page 7 of 9 - The ...
https://www.the-rheumatologist.org/article/doest-rheumatoid-arthritis-take-a-toll/7/
Additionally, the constitutive expression of inflammatory cytokines by RA synovial tissue explant cultures was suppressed by a TLR4 inhibitor. These ...
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65 Acupuncture Alleviates Rheumatoid Arthritis Swelling And Pain
https://www.healthcmi.com/Acupuncture-Continuing-Education-News/1892-acupuncture-alleviates-rheumatoid-arthritis-swelling-and-pain
Xu, “Effect of Electroacupuncture in “Zusanli” and “Kunlun” Acupoints on TLR4 Signaling Pathway of Adjuvant Arthritis Rats,” American Journal ...
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66 Ankylosing Spondylitis and Undifferentiated ...
https://emedicine.medscape.com/article/332945-overview
Other clinical manifestations include peripheral arthritis, ... compared with that in patients with a disease such as rheumatoid arthritis.
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67 Rheumatoid arthritis - innate and adaptive immune system
https://www.youtube.com/watch?v=u7cADkgaP4c
Rheumatoid arthritis - innate and adaptive immune system. 993 views 7 years ago. Simon R. Downes - Med School Radio - USICO Care.
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68 Scientists identify reversible molecular defect underlying ...
https://med.stanford.edu/news/all-news/2019/02/scientists-identify-defect-underlying-rheumatoid-arthritis.html
In rheumatoid arthritis, immune cells called helper T cells behave differently from their counterparts in healthy cells and in other ...
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69 Inflammation Regulation: The Mechanism Behind It - LabRoots
https://www.labroots.com/trending/immunology/2156/inflammation-regulation-the-mechanism-behind-it
... that have potential to be used in new therapeutic options for autoimmune disorders related to inflammation, like rheumatoid arthritis.
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70 Chronic fatigue syndrome - Wikipedia
https://en.wikipedia.org/wiki/Chronic_fatigue_syndrome
Chronic fatigue syndrome (CFS), also called myalgic encephalomyelitis (ME) or ME/CFS, ... Specialty · Rheumatology, rehabilitation medicine, endocrinology, ...
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71 What is Rheumatoid Arthritis? - News Medical
https://www.news-medical.net/health/What-is-Rheumatoid-Arthritis.aspx
Rheumatoid arthritis or RA is an inflammatory condition that affects joints primarily leading to pain and stiffness and difficulty in movements.
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72 Rheumatoid Arthritis Treatment Options
https://www.hopkinsarthritis.org/arthritis-info/rheumatoid-arthritis/ra-treatment/
Rheumatoid arthritis treatment options include medications, reduction of joint stress, physical and occupational therapy, and surgical intervention.
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73 Rheumatoid Arthritis: 8 Things That Are Difficult To Explain
https://www.everydayhealth.com/rheumatoid-arthritis/rheumatoid-arthritis-confusing/
Rheumatoid arthritis is misunderstood. It causes variable symptoms; pain and stiffness can vary. The variability and unpredictability is hard to understand.
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74 Key to spreading inflammation in rheumatoid arthritis found
https://cosmosmagazine.com/science/inflammation-rheumatoid-arthritis/
Remote inflammation in rheumatoid arthritis spreads by neuron crosstalk, and the molecule adenosine triphosphate (ATP) plays a key role in ...
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75 Rheumatoid arthritis might have a new culprit: bacteria in the gut
https://www.inquirer.com/health/newly-discovered-species-of-bacteria-in-the-microbiome-may-be-a-culprit-behind-rheumatoid-arthritis-20221119.html
Rheumatoid arthritis affects 1 in 100 people worldwide. ... Rheumatoid arthritis leads to painful joint inflammation, often in the hands and ...
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76 Rheumatoid Arthritis Therapy - Brigham and Women's Hospital
https://www.brighamandwomens.org/medical-resources/rheumatoid-arthritis-therapy
Patients seeking the foremost rheumatoid arthritis therapy available can find comprehensive arthritis treatment at the Center for Arthritis & Joint Diseases ...
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77 Rheumatoid Arthritis - RA Treatments - Patient Education Videos
https://www.ypo.education/rheumatology/rheumatoid-arthritis-t60/video/
Patient Education Videos
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78 TLR4-Dependent Homeostasis and Immunopathology: Focus on ...
https://books.google.com/books?id=BYibEAAAQBAJ&pg=PA67&lpg=PA67&dq=rheumatoid+arthritis+tlr4&source=bl&ots=d1wniF-FB7&sig=ACfU3U0q0Eu67DYGBNjQg4g3nn1x9E8P5w&hl=en&sa=X&ved=2ahUKEwiFm47bzt77AhULCd4KHVIHDEwQ6AF6BQivAhAD
Once engaged by CD14, TLR4-MD2 undergoes an internalization process and moves ... inflammatory pathologies such as atherosclerosis, rheumatoid arthritis, ...
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79 Tetraspanins - Page 237 - Google Books Result
https://books.google.com/books?id=zXNHAAAAQBAJ&pg=PA237&lpg=PA237&dq=rheumatoid+arthritis+tlr4&source=bl&ots=2_wWFGWI2Z&sig=ACfU3U2Jtae6KrGBWsnxmgz_CTtwlntcVg&hl=en&sa=X&ved=2ahUKEwiFm47bzt77AhULCd4KHVIHDEwQ6AF6BQisAhAD
CD81 has been reported as being in close proximity to TLR4 by ... diseases such as rheumatoid arthritis, multiple sclerosis and atherosclerosis.
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80 Rheumatology E-Book - Page 776 - Google Books Result
https://books.google.com/books?id=WCmhAwAAQBAJ&pg=PA776&lpg=PA776&dq=rheumatoid+arthritis+tlr4&source=bl&ots=REsmv2ERzF&sig=ACfU3U1mZRHPx1ohXlHl3ipGsqkaqUVdbA&hl=en&sa=X&ved=2ahUKEwiFm47bzt77AhULCd4KHVIHDEwQ6AF6BQiiAhAD
In mice, IL-18 can promote collagen-induced arthritis by substituting for ... and TLR4 is higher in RA than in control fibroblasts.104,105 Stimulation of ...
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81 Molecular Medical Microbiology - Page 456 - Google Books Result
https://books.google.com/books?id=rlxzAwAAQBAJ&pg=PA456&lpg=PA456&dq=rheumatoid+arthritis+tlr4&source=bl&ots=rd7Ll-a_BM&sig=ACfU3U0IVKSrpOjWGt8_Wo9qiG6pn7Qznw&hl=en&sa=X&ved=2ahUKEwiFm47bzt77AhULCd4KHVIHDEwQ6AF6BQiuAhAD
... systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) below), one of the regulators of TLR signalling, A20, which negatively controls TRAF6 ...
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82 Molecular and Physiological Basis of Nematode Survival
https://books.google.com/books?id=Z4grWIilnVkC&pg=PA78&lpg=PA78&dq=rheumatoid+arthritis+tlr4&source=bl&ots=plxuapzrs6&sig=ACfU3U3dQNOZAn3dTU2S7CJTV1aRAKNRHg&hl=en&sa=X&ved=2ahUKEwiFm47bzt77AhULCd4KHVIHDEwQ6AF6BQitAhAD
... from rheumatoid arthritis patients. Again, PC-conjugated proteins share these properties and such PC-mediated immunomodulation is dependent on TLR4.
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83 Loss of Epithelial Barrier Integrity in Inflammatory ...
https://books.google.com/books?id=EYZbEAAAQBAJ&pg=PA70&lpg=PA70&dq=rheumatoid+arthritis+tlr4&source=bl&ots=xWvyHOQiri&sig=ACfU3U1G3oeTXtsVj2XzcYN7qR5UPNJo6Q&hl=en&sa=X&ved=2ahUKEwiFm47bzt77AhULCd4KHVIHDEwQ6AF6BQidAhAD
Here TLR-proinflammatory cytokine module is instrumental for the clearance of the ... bowel disease (IBD), ankylosing spondylitis and rheumatoid arthritis.
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