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1 Aging of the striatum: mechanisms and interventions - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585651/
With age both functional and anatomical alterations occur in the nigrostriatum system. Of these alterations, decline of D2R numbers in the striatum is one of ...
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2 Mapping microstructural gradients of the human ... - Science
https://www.science.org/doi/10.1126/sciadv.abm1971
Normal aging is often associated with motor decline and therefore has been proposed to involve striatal changes (2, 26, 27).
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3 Effects of Aging in the Striatum and Substantia Nigra of a ...
https://journals.sagepub.com/doi/full/10.1177/0192623318767065
Aging is a multifactorial process associated with functional deficits, and the brain is more prone to developing chronic degenerative ...
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4 Iron Level and Myelin Content in the Ventral Striatum Predict ...
https://www.jneurosci.org/content/36/12/3552
SIGNIFICANCE STATEMENT Memory decline in healthy elderly is a common phenomenon, but the underlying neural mechanisms remain unclear. We used a ...
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5 Cognitive fatigue and cortical-striatal network in old age
https://www.aging-us.com/article/101915/text
Cognitive fatigue (CF) is among the most common and disturbing aging symptoms, and substantially interferes with activities demanding sustained mental ...
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6 Differential aging of the human striatum: a prospective MR ...
http://www.ajnr.org/content/19/8/1501
We examined age-related differences and longitudinal changes in the volume of the striatal nuclei, compared longitudinal measures of changes ...
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7 Aging-Related Dysfunction of Striatal Cholinergic Interneurons ...
https://www.cell.com/neuron/pdf/S0896-6273(16)00185-9.pdf
Aging-Related Dysfunction of Striatal Cholinergic ... activation of projection neurons in the striatum. Toxi-.
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8 Iron accumulation in the striatum predicts aging-related ...
https://www.sciencedirect.com/science/article/abs/pii/S0197458005004549
This suggests that striatal iron levels may be a biomarker of motor dysfunction in aging; and as such, can be monitored non-invasively by longitudinal brain MRI ...
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9 MR‐based age‐related effects on the striatum, globus pallidus ...
https://onlinelibrary.wiley.com/doi/full/10.1002/hbm.24771
MR-based age-related effects on the striatum, globus pallidus, and thalamus in healthy individuals across the adult lifespan.
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10 Age-related Huntington's disease progression modeled in ...
https://www.nature.com/articles/s41593-022-01185-4
In this study we examined striatal medium spiny neurons (MSNs) directly reprogrammed from fibroblasts of patients with HD to model the age- ...
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11 Parkinson's disease-related Leucine-rich repeat kinase 2 ...
https://molecularneurodegeneration.biomedcentral.com/articles/10.1186/s13024-020-00360-0
Alteration of gene expression in Lrrk2−/− striatal neurons during aging. a The volcano plots of RNA-seq data collected from the dorsal ...
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12 Effects of aging on nitrergic neurons in human striatum and ...
https://www.scielo.br/j/anp/a/tK3ndzLFdm6BVvTQgskrh6s/?lang=en
Our data showed aging does not modify the neuronal density and size of nitrergic neurons in striatum and subthalamic nucleus. These findings suggest a lack of ...
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13 Differential aging of the human striatum: longitudinal ... - VIVO
https://vivo.weill.cornell.edu/display/pubid14561615
We examined age-related differences and longitudinal changes in the volume of the striatal nuclei, compared longitudinal measures of changes ...
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14 Dopaminergic Modulation of Aging Striatum - Michael Levine
https://grantome.com/grant/NIH/R01-AG007462-01
The changes in membrane properties of striatal neurons during aging will also be determined. In a second series of experiments immunohistochemical procedures ...
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15 Dissociation of Striatal Dopamine and Tyrosine Hydroxylase ...
https://academic.oup.com/biomedgerontology/article/73/1/11/3872273
The aging-related decline in locomotor activity was prevented by CR. However, striatal DA or TH expression was decreased in the CR group, but increased in ...
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16 Differential aging of the human striatum: longitudinal evidence.
https://www.semanticscholar.org/paper/Differential-aging-of-the-human-striatum%3A-evidence.-Raz-Rodrigue/56bb9fb2705fc497883d97b85125ee1bd5733f69
Although cross-sectional estimates suggested preservation of some striatal nuclei, longitudinal shrinkage of the whole striatum was evident ...
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17 Effect of Aging on 24-Hour Changes in Dopamine and ...
https://www.karger.com/article/Abstract/68258
Keywords: AgingCorpus striatumCircadian rhythmsExcitatory amino acidsInhibitory amino ... The striatal serotonin and dopamine turnover was also measured.
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18 Age-Related Differences in Ventral Striatal and Default Mode ...
https://www.biorxiv.org/content/10.1101/2021.07.29.454071v1.full
We found that striatal responses to reciprocated trust from friends relative to strangers and computers were blunted in older adults relative to ...
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19 Age-Related Decline in Dopamine Transporters
https://medicine.yale.edu/psychiatry/alzheimers/images/american%202002_tcm467-85801.pdf
V3 for the striatum and striatal subregions (caudate and putamen) was computed without conversion of. SPECT counts per minute (cpm) to absolute units of.
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20 Age- and Sex-Dependence of Dopamine Release and ... - PLOS
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0099592
The dorsal striatum is the main input structure of the basal ganglia and the major target area of dopaminergic projections originating in ...
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21 Study on the Mechanism of Exercise Adaptability between ...
https://www.amazon.com/Mechanism-Exercise-Adaptability-Cerebral-Striatum/dp/7518970953
Study on the Mechanism of Exercise Adaptability between Cerebral Striatum Aging and Lesion(Chinese Edition) [LIU WEN FENG] on Amazon.com.
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22 Morphometry of the human cortex cerebri and corpus striatum ...
https://psycnet.apa.org/record/1992-09786-001
Comments in D. F. Swaab's (see record 1992-09836-001) article on aging and presents results of biological aging research using human brain material after ...
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23 Morphochemical changes in human striatum during aging.
https://europepmc.org/article/med/31228369
Age-related neurodegenerative diseases, including Parkinson's disease, are characterized by a number of pathomorphological signs, such as neuron loss in ...
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24 Mapping microstructural gradients of the human ... - NASA/ADS
https://ui.adsabs.harvard.edu/abs/2022SciA....8M1971D/abstract
By exploiting multiparametric quantitative MRI, we found distinct, spatially dependent, aging-related alterations in water content and iron concentration.
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25 JMD : Journal of Movement Disorders
https://www.e-jmd.org/journal/view.php?number=141
In addition, striatal DAT activity declines with aging, ... The age-related decline in DAT activity mainly impacts the striatum in controls ...
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26 Frontal-Striatal Circuits in Cognitive Aging
https://www.tandfonline.com/doi/abs/10.1076/1382-5585%28199912%2906%3A04%3B1-B%3BFT241
Changes in cognition with aging have been claimed to be due in large part to a decline in frontal lobe function.
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27 Metabolism Changes During Aging in the Hippocampus and ...
https://kuscholarworks.ku.edu/handle/1808/24650
Metabolism Changes During Aging in the Hippocampus and Striatum of Glud1 (Glutamate Dehydrogenase 1) Transgenic Mice · View/Open · Issue Date · Author · Publisher.
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28 Possible "Accelerated Striatal Aging" Induced by 56Fe Heavy ...
https://www.jstor.org/stable/3578484
Possible "Accelerated Striatal Aging" Induced by 56Fe Heavy-Particle. Irradiation: Implications for Manned Space Flights. J. A. JOSEPH,' W. A. HUNT,2 B. M. ...
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29 Swiss Cheese Striatum: Clinical Implications - JAMA Network
https://jamanetwork.com/journals/jamaneurology/fullarticle/1859982
... enlarged Virchow-Robin spaces throughout the striatum appear occasionally on magnetic resonance imaging (MRI) scans of the elderly, ...
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30 Epidemiology epiBRAIN Journal Club - Pitt Public Health
https://www.publichealth.pitt.edu/epibrain/moduleid/12956/itemid/1164/mctl/eventdetails
Aging, striatal dopamine, and movement The aging striatal dopamine function . O Darbin. Parkinsonism and Related Disorders 18 (2012) 426-432 ...
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31 Impact of Dysfunctional BNDF on Dopamine Terminal ...
https://asi.syr.edu/caps-grant/impact-of-dysfunctional-bndf-on-dopamine-terminal-remodeling-in-the-parkinsonian-striatum/
... BNDF on Dopamine Terminal Remodeling in the Parkinsonian Striatum ... with age in the pathology and treatment of Parkinson's disease.
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32 (PDF) Effects of Aging in the Striatum and Substantia Nigra of ...
https://www.researchgate.net/publication/324701750_Effects_of_Aging_in_the_Striatum_and_Substantia_Nigra_of_a_Parkinson's_Disease_Animal_Model
PDF | Aging is a multifactorial process associated with functional deficits, and the brain is more prone to developing chronic degenerative diseases.
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33 Age-related changes in midbrain dopaminergic regulation of ...
https://www.pnas.org/content/105/39/15106
During reward anticipation (Fig. 1A), young subjects recruited the ventral striatum, the anterior cingulate cortex, and the left intraparietal ...
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34 Aging and Functional Reorganization of Striatum - edoc-Server
https://edoc.hu-berlin.de/bitstream/handle/18452/17425/schuck.pdf?sequence=1
Aging and Functional Reorganization of. Striatum- and Medial-Temporal. Lobe-Dependent Memory Systems. Dissertation.
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35 Striatal glutamatergic neurotransmission and plasticity in ...
https://openarchive.ki.se/xmlui/handle/10616/46300
Parkinson's disease (PD) is a devastating neurodegenerative disorder with aging as the main risk factor. PD is characterized by severe ...
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36 lynx1 Supports Neuronal Health in the Mouse Dorsal Striatum ...
https://librarysearch.hillsdale.edu/discovery/fulldisplay?docid=cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4265479&context=PC&vid=01HC_INST:01HC_INST&lang=en&search_scope=MyInst_and_CI&adaptor=Primo%20Central&tab=Everything&query=null%2C%2CBoston%20%3A%20Academic%20Press%2CAND&mode=advanced&offset=70
Nicotinic acetylcholine receptors have been shown to participate in neuroprotection in the aging brain. Lynx protein modulators dampen the activity of the ...
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37 Age-related differences in striatal dopamine D1 receptors ... - JCI
https://www.jci.org/articles/view/164799
Age-related differences in striatal dopamine D1 receptors mediate subjective drug effects. Peter Manza,1 Ehsan Shokri-Kojori,1 Sukru B.
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38 Inactivation of the striatum in aged rats rescues their ability to ...
https://amygdala.psychdept.arizona.edu/labspace/JclubLabMeetings/Sayu.%20Inactivation%20of%20the%20striatum%20in%20aged%20rats%20rescues%20their%20ability%20to%20learn%20a%20hippocampus-sensitive%20spatial%20navigation%20task-091021.pdf
Aging. Spatial learning. Memory modulation. Memory system competition. Hippocampus. Striatum. Lidocaine. A B S T R A C T.
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39 Know Your Brain: Striatum - Neuroscientifically Challenged
https://neuroscientificallychallenged.com/posts/know-your-brain-striatum
Striatum (in red). The striatum refers to a small group of contiguous subcortical structures: the caudate, putamen, and nucleus accumbens. The caudate and ...
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40 Iris Publication - UCL IRIS
https://iris.ucl.ac.uk/iris/publication/1741674/1
The Role of the Striatum in Learning to Orthogonalize Action and Valence: A Combined PET and 7 T MRI Aging Study. Publication Type:.
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41 Brain metabolism in health, aging, and neurodegeneration
https://www.embopress.org/doi/10.15252/embj.201695810
By altering the interactions between prefrontal cortex and structures such as the hippocampus and striatum, white matter abnormalities result in poor ...
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42 Subtle Neuronal Death in Striatum After Short Forebrain ...
https://www.ahajournals.org/doi/full/10.1161/01.str.28.1.163
Recently, a report appeared showing the increased occurrence of apoptotic neurons in the aging rat striatum. Significantly, a recent study on reserpine ...
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43 Age-Related Decline in Dopamine Transporters: Analysis of ...
https://www.ajgponline.org/article/S1064-7481(12)61325-6/fulltext
Neuroimaging studies have documented an age-related decline in striatal dopamine transporters (DATs) as a marker of dopaminergic neurodegeneration.
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44 Neuroscience of aging - Wikipedia
https://en.wikipedia.org/wiki/Neuroscience_of_aging
The neuroscience of aging is the study of the changes in the nervous system that occur with ... and striatum to a small extent in a process called adult neurogenesis.
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45 Impact of Aging on the 6-OHDA-Induced Rat Model of ... - MDPI
https://www.mdpi.com/1422-0067/21/10/3459/htm
The results showed that aging had a negative impact on animal welfare after ... Finally, the extension of dopaminergic degeneration within the striatum and ...
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46 Genetic Predisposition for Inflammation Exacerbates Effects of ...
https://utd-ir.tdl.org/handle/10735.1/8916
Older age was associated with greater striatal iron content that in turn ... a complex mechanism of neural and cognitive decline in aging.
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47 Researchers discover crucial role of brain's ... - ScienceDaily
https://www.sciencedaily.com/releases/2022/11/221130151535.htm
May 21, 2019 — Results of a new study reports that parental age is linked to the risk for the development of neuropsychiatric disorders in ...
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48 UCI researchers discover crucial role of brain's striatum cilia in ...
https://www.newswise.com/articles/uci-researchers-discover-crucial-role-of-brain-s-striatum-cilia-in-time-perception
The striatum processes and integrates new environmental sensory information and coordinates the time sequence of motor responses. A common ...
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49 Experiences of Daily Stress Decrease as People Age
https://neurosciencenews.com/stress-aging-21977/
Krill oil rewires distinct gene expression programs that contribute to attenuating several aging hallmarks, including oxidative stress, ...
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50 2-Minute Neuroscience: Striatum - YouTube
https://www.youtube.com/watch?v=EEUxKFmIUiI
Neuroscientifically Challenged
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51 Cumulated Index Medicus
https://books.google.com/books?id=zwf49rhqJMgC&pg=PA15021&lpg=PA15021&dq=striatum+aging&source=bl&ots=Q3YX0mBVJu&sig=ACfU3U2YBq1HnSe39fEXIVZ_bxrex6EgLA&hl=en&sa=X&ved=2ahUKEwi77Y_Azt77AhWZmHIEHXwcDpoQ6AF6BQiMAhAD
D2 dopamine receptor activation inhibits basal and intra - striatal ... 297 ( 1-2 ) : 47-51 In vivo amino acid release from the striatum of aging rats ...
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52 3D Brain - BrainFacts
https://www.brainfacts.org/3d-brain
Aging · Brain Development · Childhood & Adolescence · Diet & Lifestyle · Emotions, Stress & Anxiety · Hearing · Language · Learning & Memory · Movement ...
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53 Molecular Aspects of Development and Aging of the Nervous System
https://books.google.com/books?id=l8EGCAAAQBAJ&pg=PA30&lpg=PA30&dq=striatum+aging&source=bl&ots=zDpTW9EUJF&sig=ACfU3U3rmRppcv73mYoqrJ5rdTiBGdQ9ZQ&hl=en&sa=X&ved=2ahUKEwi77Y_Azt77AhWZmHIEHXwcDpoQ6AF6BQiUAhAD
Time Course of GFAP, PPE and a-Tubulin mRNA in the Striatum following 6-OHDA Lesion of substantia nigra GFAP mRNA levels elevated only in the ipsilateral ...
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54 Extramural Research and Training Program: Grant and Contract ...
https://books.google.com/books?id=O2jCok5sDpMC&pg=PA53&lpg=PA53&dq=striatum+aging&source=bl&ots=UJ4bL3KhpK&sig=ACfU3U0Q8sTSXtXdYJhMQICRQwwjZDLAag&hl=en&sa=X&ved=2ahUKEwi77Y_Azt77AhWZmHIEHXwcDpoQ6AF6BQiTAhAD
Grant and Contract Summaries National Institute on Aging ... study of Parkinson's disease in which the striatum is badly damaged and undergoes RNA loss .
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55 Dynamics of decision making: from evidence to preference and ...
https://books.google.com/books?id=VZkgBQAAQBAJ&pg=PA88&lpg=PA88&dq=striatum+aging&source=bl&ots=lUcM8WOJmp&sig=ACfU3U0bbXuFKBI_Dq_yAIYCJxhXEVKI9A&hl=en&sa=X&ved=2ahUKEwi77Y_Azt77AhWZmHIEHXwcDpoQ6AF6BQiVAhAD
This age-dependent change in the decision boundary may be due to structural limits in pre-SMA and striatal connectivity (Forstmann et al., ...
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56 Effects of the COVID-19 Pandemic on Mental Health and Brain ...
https://www.bpsgos.org/article/S2667-1743(22)00142-2/fulltext
For example, cortical thickness, which decreases with age ( ... a brain age gap estimate (BrainAGE) suggestive of accelerated aging (i.e., ...
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57 Researchers discover crucial role of brain's ... - Medical Xpress
https://medicalxpress.com/news/2022-11-crucial-role-brain-striatum-cilia.html
Selective cilia deletion in the striatum and confirmation of mice's ... ablation of cilia in the dorsal striatum neurons of Ift88fl mice ...
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58 Life Science News
https://www.news-medical.net/life-sciences/news
Collaborative work unravels hidden molecular secrets of age-related diseases ... Removal of cilia from the brain's striatum impairs time perception and ...
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59 Cities, cells, and the neuroscience of navigation - Many Minds
https://manyminds.libsyn.com/cities-cells-and-the-neuroscience-of-navigation
... interactions between the hippocampus and the striatum in navigation. ... and examine effects of variables like age, gender, and nationality.
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60 Depression and Cognitive Impairment: Current Understanding ...
https://www.dovepress.com/depression-and-cognitive-impairment-current-understanding-of-its-neuro-peer-reviewed-fulltext-article-NDT
Positive attentional bias drastically decreases regardless of age, ... general striatal and limbic modifications as well as particular, ...
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61 The Next UBCH Physician Appreciation Networking Lunch is ...
https://psychiatry.ubc.ca/?cat=-1%2Fpage%2F3%2F%2Fpage%2F3%2F
... interest in depression and/or Polish society and/or the stigma of aging. ... DAT density in the striatum with more pronounced reduction in individuals ...
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62 Alleviating the burden of balance decline with aging
https://www.hebrewseniorlife.org/blog/alleviating-burden-balance-decline-aging
› blog › alleviating-b...
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63 How Does Aging Affect The Nervous System? Top Full Guide ...
https://www.restorbio.com/how-does-aging-affect-the-nervous-system/
There is no cure. The treatment for Parkinson's disease focuses on increasing the dopamine levels within the striatum. The most common method of increasing ...
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64 Striatum | Psychology Wiki | Fandom
https://psychology.fandom.com/wiki/Striatum
› wiki › Striatum
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65 Biomarkers used to track benefits of anti-aging therapies can ...
https://phys.org/news/2022-09-biomarkers-track-benefits-anti-aging-therapies.html
Individuals could use a biomarker of aging to track their biological age over time, measure the effect of diet, exercise, and drugs and predict ...
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66 Mysterious Tendrils Inside The Brain May Control Our ...
https://agingadjustments.com/parkinsons-disease/mysterious-tendrils-inside-the-brain-may-control-our-perception-of-time/
2022 - Aging Adjustments. All Rights Reserved. Created By: Sawah Dev. This website uses cookies to improve your experience.
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67 A Positron Emission Tomography Study of Dopamine ...
https://psychiatry.dev/tts/2022/11/a-positron-emission-tomography-study-of-dopamine-transporter-density-in-patients-with-bipolar-disorder-with-current-mania-and-those-with-recently-remitted-mania-2/
To assess dopamine transporter (DAT) density in the striatum in patients ... Of 47 total participants (mean [SD] age, 37.8 [14.4] years), ...
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68 Ageing and the Brain - Physiopedia
https://www.physio-pedia.com/Ageing_and_the_Brain
After a certain age, which varies from person to person, brain function declines. The brain's size, vasculature, and cognition all change as we get older. With ...
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69 Archives of Internal Medicine
https://books.google.com/books?id=L4zyAAAAMAAJ&pg=PA652&lpg=PA652&dq=striatum+aging&source=bl&ots=5JGEBr-pHy&sig=ACfU3U1aiQct2YP5c6vyrxl-nygVK3QeUg&hl=en&sa=X&ved=2ahUKEwi77Y_Azt77AhWZmHIEHXwcDpoQ6AF6BQiNAhAD
... striatum , and the seat of the essential lesion in paralysis agitans . ... its appearance in the fifteenth year , death supervening at the age of 40 .
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70 Annual Report - Page 593 - Google Books Result
https://books.google.com/books?id=AkcrAAAAYAAJ&pg=PA593&lpg=PA593&dq=striatum+aging&source=bl&ots=q1Vtp4PNhC&sig=ACfU3U0AdmMEdXN4feUarlfIQ8oX3sInBg&hl=en&sa=X&ved=2ahUKEwi77Y_Azt77AhWZmHIEHXwcDpoQ6AF6BQiLAhAD
Male , age 54 — Chronic productive leptomeningitis , cyst of the left corpus striatum and internal càpsule , softening of both lenticular nuclei and optic ...
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71 Guy's hospital reports - Volume 23 - Page 23 - Google Books Result
https://books.google.com/books?id=LLPtfiGdp3IC&pg=PA23&lpg=PA23&dq=striatum+aging&source=bl&ots=xhNA--aE7c&sig=ACfU3U37r1HUhIiLzGTpuh2KfHiVxfxJAQ&hl=en&sa=X&ved=2ahUKEwi77Y_Azt77AhWZmHIEHXwcDpoQ6AF6BQiKAhAD
... the affection of the limbs has commenced at a very early age , many patients ... and then there is found a small lesion in the right corpus striatum ...
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72 The Ups and Downs of Aging: What Neuroscience Can Teach ...
https://piphd.com/articles-2/2019/8/26/the-ups-and-downs-of-aging
Work from my research colleagues has demonstrated that older adults showing greater physical activity had less age-related decline in dopamine ...
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73 Dance, garden and swim your way to a better brain as ... - CNN
https://www.cnn.com/2020/03/05/health/activity-prevents-brain-shrinkage-older-adults-wellness/index.html
A new study finds that leisurely physical activity such as walking, gardening, swimming and dancing may slow brain aging in older adults, ...
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