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Google Keyword Rankings for : type 2 diabetes tcf7l2
1
The Role of TCF7L2 in Type 2 Diabetes - PubMed
https://pubmed.ncbi.nlm.nih.gov/34016596/
The precise genetic defect that causes the association of TCF7L2 with type 2 diabetes remains unclear. There is a large number of highly correlated variants, ...
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https://pubmed.ncbi.nlm.nih.gov/34016596/
The precise genetic defect that causes the association of TCF7L2 with type 2 diabetes remains unclear. There is a large number of highly correlated variants, ...
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2
Type 2 Diabetes Mellitus and TCF7L2 - Medscape Reference
https://emedicine.medscape.com/article/1788533-overview
TCF7L2 was discovered as a type 2 diabetes susceptibility gene after a strong linkage signal was mapped to chromosome 10q in a Mexican-American ...
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https://emedicine.medscape.com/article/1788533-overview
TCF7L2 was discovered as a type 2 diabetes susceptibility gene after a strong linkage signal was mapped to chromosome 10q in a Mexican-American ...
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3
TCF7L2 is a master regulator of insulin production and ...
https://academic.oup.com/hmg/article/23/24/6419/605889
TCF7L2 harbors common genetic variants with the strongest effect on type 2 diabetes (T2D) risk yet described, i.e. the single-nucleotide polymorphism (SNP ...
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https://academic.oup.com/hmg/article/23/24/6419/605889
TCF7L2 harbors common genetic variants with the strongest effect on type 2 diabetes (T2D) risk yet described, i.e. the single-nucleotide polymorphism (SNP ...
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4
No detectable effect of a type 2 diabetes-associated TCF7L2 ...
https://ec.bioscientifica.com/view/journals/ec/9/12/EC-20-0471.xml
The T allele of TCF7L2 rs7903146 is a common genetic variant associated with type 2 diabetes (T2D), possibly by modulation of incretin action.
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https://ec.bioscientifica.com/view/journals/ec/9/12/EC-20-0471.xml
The T allele of TCF7L2 rs7903146 is a common genetic variant associated with type 2 diabetes (T2D), possibly by modulation of incretin action.
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5
Prime suspect: the TCF7L2 gene and type 2 diabetes risk
https://www.jci.org/articles/view/33077
In all populations, TCF7L2 showed strong association, with the odds of developing type 2 diabetes being increased by 30%–50% for each allele ...
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https://www.jci.org/articles/view/33077
In all populations, TCF7L2 showed strong association, with the odds of developing type 2 diabetes being increased by 30%–50% for each allele ...
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6
The TCF7L2 rs7903146 (T) allele is associated with type 2 ...
https://bmcmedgenet.biomedcentral.com/articles/10.1186/1471-2350-14-96
TCF7L2 is involved in insulin secretion, and the TCF7L2 rs7903146 single nucleotide polymorphism (SNP) constitutes the best established risk ...
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https://bmcmedgenet.biomedcentral.com/articles/10.1186/1471-2350-14-96
TCF7L2 is involved in insulin secretion, and the TCF7L2 rs7903146 single nucleotide polymorphism (SNP) constitutes the best established risk ...
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7
TCF7L2 Polymorphisms and Progression to Diabetes in the ...
https://www.nejm.org/doi/full/10.1056/nejmoa062418
Common variants in TCF7L2 seem to be associated with an increased risk of diabetes among persons with impaired glucose tolerance. The risk- ...
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https://www.nejm.org/doi/full/10.1056/nejmoa062418
Common variants in TCF7L2 seem to be associated with an increased risk of diabetes among persons with impaired glucose tolerance. The risk- ...
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8
Variant of transcription factor 7-like 2 (TCF7L2) gene confers ...
https://www.nature.com/articles/ng1732
Variants of the TCF7L2 gene could influence the susceptibility to type 2 diabetes by altering levels of the insulinotropic hormone glucagon-like ...
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https://www.nature.com/articles/ng1732
Variants of the TCF7L2 gene could influence the susceptibility to type 2 diabetes by altering levels of the insulinotropic hormone glucagon-like ...
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9
Transcription Factor 7-Like-2 (TCF7L2) rs7903146 (C/T ...
https://www.karger.com/Article/Fulltext/509756
T2DM is a multifactorial disease including several environmental factors with the presence of genetic predisposition. ... Then, TCF7L2 gene seems to affect ...
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https://www.karger.com/Article/Fulltext/509756
T2DM is a multifactorial disease including several environmental factors with the presence of genetic predisposition. ... Then, TCF7L2 gene seems to affect ...
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10
The broad pathogenetic role of TCF7L2 in human diseases ...
https://onlinelibrary.wiley.com/doi/full/10.1002/jcp.30581
Later, the TCF7L2 gene was linked to type 2 diabetes (T2D), implicating TCF7L2 and Wnt-signaling in metabolic disorders and homeostasis.
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https://onlinelibrary.wiley.com/doi/full/10.1002/jcp.30581
Later, the TCF7L2 gene was linked to type 2 diabetes (T2D), implicating TCF7L2 and Wnt-signaling in metabolic disorders and homeostasis.
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11
Possible role of TCF7L2 in the pathogenesis of type 2 ...
https://www.tandfonline.com/doi/full/10.1080/13102818.2018.1438211
Variant of transcription factor 7 like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet. 2006;38(3):320–323. [Crossref], [PubMed], [Web of Science ®], ...
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https://www.tandfonline.com/doi/full/10.1080/13102818.2018.1438211
Variant of transcription factor 7 like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet. 2006;38(3):320–323. [Crossref], [PubMed], [Web of Science ®], ...
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12
Association of TCF7L2 variation with single islet autoantibody ...
https://drc.bmj.com/content/2/1/e000008
Background The transcription factor 7-like 2 (TCF7L2) gene has the strongest genetic association with type 2 diabetes. TCF7L2 also associates with latent ...
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https://drc.bmj.com/content/2/1/e000008
Background The transcription factor 7-like 2 (TCF7L2) gene has the strongest genetic association with type 2 diabetes. TCF7L2 also associates with latent ...
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13
Evaluation of the TCF7L2 gene as a predictor of type 2 diabetes
https://www.cdc.gov/genomics/hugenet/casestudy/diabetes/diabetes_tcf7l2.htm
In February 2006, Grant et al. reported that a variant of the TCF7L2 gene is associated with type 2 diabetes (T2D). Grant SF, et al.
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https://www.cdc.gov/genomics/hugenet/casestudy/diabetes/diabetes_tcf7l2.htm
In February 2006, Grant et al. reported that a variant of the TCF7L2 gene is associated with type 2 diabetes (T2D). Grant SF, et al.
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14
TCF7L2 and type 2 diabetes—we WNT to know | SpringerLink
https://link.springer.com/article/10.1007/s00125-006-0521-z
[1] that variants in the TCF7L2 gene are strongly associated with risk of developing type 2 diabetes has now been robustly reproduced in ...
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https://link.springer.com/article/10.1007/s00125-006-0521-z
[1] that variants in the TCF7L2 gene are strongly associated with risk of developing type 2 diabetes has now been robustly reproduced in ...
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15
Differential Methylation of TCF7L2 Promoter in Peripheral ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0099310
TCF7L2 is the susceptibility gene for Type 2 diabetes (T2D) with the largest effect on disease risk that has been discovered to date.
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https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0099310
TCF7L2 is the susceptibility gene for Type 2 diabetes (T2D) with the largest effect on disease risk that has been discovered to date.
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16
What Can Diabetes-Associated Genetic Variation in TCF7L2 ...
https://www.liebertpub.com/doi/10.1089/met.2018.0024
Type 2 diabetes mellitus (T2DM) is a polygenic metabolic disorder characterized by hyperglycemia occurring as a result of impaired insulin ...
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https://www.liebertpub.com/doi/10.1089/met.2018.0024
Type 2 diabetes mellitus (T2DM) is a polygenic metabolic disorder characterized by hyperglycemia occurring as a result of impaired insulin ...
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17
TCF7L2 Polymorphism Associates with New-Onset Diabetes ...
https://jasn.asnjournals.org/content/20/11/2459
Each T allele of the key TCF7L2 SNP rs7903146 increased type 2 diabetes risk with an OR of 1.37. We observed no significant association of NODAT ...
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https://jasn.asnjournals.org/content/20/11/2459
Each T allele of the key TCF7L2 SNP rs7903146 increased type 2 diabetes risk with an OR of 1.37. We observed no significant association of NODAT ...
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18
TCF7L2 Gene Polymorphisms and Susceptibility to Type 2 ...
https://biomedpharmajournal.org/vol11no2/tcf7l2-gene-polymorphisms-and-susceptibility-to-type-2-diabetes-mellitus-a-pilot-study/
Transcription factor 7-like 2 (TCF7L2) variants are known risk factors of type 2 diabetes (T2DM).However, this association is not consistent ...
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https://biomedpharmajournal.org/vol11no2/tcf7l2-gene-polymorphisms-and-susceptibility-to-type-2-diabetes-mellitus-a-pilot-study/
Transcription factor 7-like 2 (TCF7L2) variants are known risk factors of type 2 diabetes (T2DM).However, this association is not consistent ...
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19
The TCF7L2 gene, type 2 diabetes and the Paleo diet
https://www.gbhealthwatch.com/HotTopic-type-2-diabetes-TCF7L2.php
Genetic variation in the TCF7L2 gene at rs7903146 confers the largest effect on risk of type 2 diabetes. The at-risk T allele is found in about 20% of the ...
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https://www.gbhealthwatch.com/HotTopic-type-2-diabetes-TCF7L2.php
Genetic variation in the TCF7L2 gene at rs7903146 confers the largest effect on risk of type 2 diabetes. The at-risk T allele is found in about 20% of the ...
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20
Brasil - The TCF7L2 rs7903146 (C/T) polymorphism ... - SciELO
https://www.scielo.br/j/abem/a/BHsMWVzcgrfKyFGvkhbdQBG/?lang=en
The frequency of the minor allele was 38% in type 2 diabetes group and 31% in non-diabetic subjects, and this allele was significantly associated with type 2 ...
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https://www.scielo.br/j/abem/a/BHsMWVzcgrfKyFGvkhbdQBG/?lang=en
The frequency of the minor allele was 38% in type 2 diabetes group and 31% in non-diabetic subjects, and this allele was significantly associated with type 2 ...
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21
The new type 2 diabetes gene TCF7L2 - Lippincott
https://journals.lww.com/co-clinicalnutrition/fulltext/2007/07000/the_new_type_2_diabetes_gene_tcf7l2.3.aspx
Common variants in the gene that encodes the transcription factor 7-like 2 (TCF7L2) have been strongly associated with type 2 diabetes.
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https://journals.lww.com/co-clinicalnutrition/fulltext/2007/07000/the_new_type_2_diabetes_gene_tcf7l2.3.aspx
Common variants in the gene that encodes the transcription factor 7-like 2 (TCF7L2) have been strongly associated with type 2 diabetes.
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22
TCF7L2 plays a complex role in human adipose progenitor ...
https://www.metabolismjournal.com/article/S0026-0495(22)00118-4/fulltext
Non-coding genetic variation at TCF7L2 is the strongest genetic determinant of type 2 diabetes (T2D) risk in humans. TCF7L2 encodes a ...
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https://www.metabolismjournal.com/article/S0026-0495(22)00118-4/fulltext
Non-coding genetic variation at TCF7L2 is the strongest genetic determinant of type 2 diabetes (T2D) risk in humans. TCF7L2 encodes a ...
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23
Polymorphism of the Transcription Factor 7-Like 2 ... - MDPI
https://www.mdpi.com/2072-6643/8/12/793
Polymorphism of the Transcription Factor 7-Like 2 Gene (TCF7L2) Interacts with Obesity on Type-2 Diabetes in the PREDIMED Study Emphasizing the Heterogeneity of ...
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https://www.mdpi.com/2072-6643/8/12/793
Polymorphism of the Transcription Factor 7-Like 2 Gene (TCF7L2) Interacts with Obesity on Type-2 Diabetes in the PREDIMED Study Emphasizing the Heterogeneity of ...
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24
Transcription factor 7-like 2 (TCF7L2): a culprit gene in Type 2 ...
https://www.dia-endojournals.ru/jour/article/view/12313?locale=en_US
Recent genetic research identifies numerous novel type 2 diabetes susceptible genes among these genes TCF7L2 is considered as gang head and emerged as the most ...
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https://www.dia-endojournals.ru/jour/article/view/12313?locale=en_US
Recent genetic research identifies numerous novel type 2 diabetes susceptible genes among these genes TCF7L2 is considered as gang head and emerged as the most ...
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25
SLC30A8, CDKAL1, TCF7L2, KCNQ1 and IGF2BP2 are ...
https://www.dovepress.com/slc30a8-cdkal1-tcf7l2-kcnq1-and-igf2bp2-are-associated-with-type-2-dia-peer-reviewed-fulltext-article-DMSO
SLC30A8, CDKAL1, TCF7L2, KCNQ1 and IGF2BP2 are Associated with Type 2 Diabetes Mellitus in Iranian Patients.
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https://www.dovepress.com/slc30a8-cdkal1-tcf7l2-kcnq1-and-igf2bp2-are-associated-with-type-2-dia-peer-reviewed-fulltext-article-DMSO
SLC30A8, CDKAL1, TCF7L2, KCNQ1 and IGF2BP2 are Associated with Type 2 Diabetes Mellitus in Iranian Patients.
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26
TCF7L2 gene associated postprandial triglyceride ... - Frontiers
https://www.frontiersin.org/articles/10.3389/fendo.2022.973718/full
Transcription factor 7 like 2 (TCF7L2) gene has been shown to have the strongest association with type 2 diabetes mellitus among all ...
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https://www.frontiersin.org/articles/10.3389/fendo.2022.973718/full
Transcription factor 7 like 2 (TCF7L2) gene has been shown to have the strongest association with type 2 diabetes mellitus among all ...
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27
2009.02_Yu_JClinEndoMetab_0.pdf
https://www.immunetolerance.org/sites/default/files/2009.02_Yu_JClinEndoMetab_0.pdf
nucleotide polymorphisms (SNPs) of transcription factor 7-like 2 (TCF7L2) gene ... Conclusion: TCF7L2 type 2 diabetes susceptibility alleles are associated ...
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https://www.immunetolerance.org/sites/default/files/2009.02_Yu_JClinEndoMetab_0.pdf
nucleotide polymorphisms (SNPs) of transcription factor 7-like 2 (TCF7L2) gene ... Conclusion: TCF7L2 type 2 diabetes susceptibility alleles are associated ...
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28
Transcription factor 7-like 2 gene links increased in vivo ...
https://www.thelancet.com/article/S2352-3964(18)30113-0/fulltext
Transcription factor 7-like 2 (TCF7L2) is the main susceptibility gene for type 2 diabetes, predominantly by affecting insulin secretion of ...
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https://www.thelancet.com/article/S2352-3964(18)30113-0/fulltext
Transcription factor 7-like 2 (TCF7L2) is the main susceptibility gene for type 2 diabetes, predominantly by affecting insulin secretion of ...
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29
Transcription Factor 7-like 2 (TCF7L2 ... - FIU Digital Commons
https://digitalcommons.fiu.edu/cgi/viewcontent.cgi?article=4913&context=etd
Xu, Ling, "Transcription Factor 7-like 2 (TCF7L2) Gene Polymorphisms in Relation to the Risk of Type 2 Diabetes in three.
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https://digitalcommons.fiu.edu/cgi/viewcontent.cgi?article=4913&context=etd
Xu, Ling, "Transcription Factor 7-like 2 (TCF7L2) Gene Polymorphisms in Relation to the Risk of Type 2 Diabetes in three.
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30
TCF7L2 Gene Polymorphism and AGEs in Diabetic ...
https://clinicaltrials.gov/ct2/show/NCT04084886
Brief Summary: ... Detailed Description: Diabetic nephropathy is one of microvascular complications of diabetes mellitus. DN is a multifactorial ...
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https://clinicaltrials.gov/ct2/show/NCT04084886
Brief Summary: ... Detailed Description: Diabetic nephropathy is one of microvascular complications of diabetes mellitus. DN is a multifactorial ...
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31
Genetic polymorphisms in TCF7L2 and PPARG genes and ...
https://www.sciencedirect.com/science/article/abs/pii/S2214540021000153
Transcription factor 7-like 2 (TCF7L2) plays an important role in insulin resistance and peroxisome proliferator-activated receptor γ (PPARG) is directly ...
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https://www.sciencedirect.com/science/article/abs/pii/S2214540021000153
Transcription factor 7-like 2 (TCF7L2) plays an important role in insulin resistance and peroxisome proliferator-activated receptor γ (PPARG) is directly ...
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32
Age at onset of obesity, transcription factor 7-like 2 (TCF7L2 ...
https://www.archivesofmedicalscience.com/Age-at-onset-of-obesity-transcription-factor-7-like-2-TCF7L2-rs7903146-polymorphism,68931,0,2.html
TCF7L2 is among the most common associated loci reported in genome-wide appraisals of type 2 diabetes, and the TCF7L2 rs7903146 SNP particularly constitutes a ...
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https://www.archivesofmedicalscience.com/Age-at-onset-of-obesity-transcription-factor-7-like-2-TCF7L2-rs7903146-polymorphism,68931,0,2.html
TCF7L2 is among the most common associated loci reported in genome-wide appraisals of type 2 diabetes, and the TCF7L2 rs7903146 SNP particularly constitutes a ...
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33
TCF7L2 gene variants raise risk of type 2 diabetes - Healio
https://www.healio.com/news/endocrinology/20120325/i-tcf7l2-i-gene-variants-raise-risk-of-type-2-diabetes
Two new studies found that common variants of the TCF7L2 gene are strongly associated with an increased risk of type 2 diabetes mellitus.
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https://www.healio.com/news/endocrinology/20120325/i-tcf7l2-i-gene-variants-raise-risk-of-type-2-diabetes
Two new studies found that common variants of the TCF7L2 gene are strongly associated with an increased risk of type 2 diabetes mellitus.
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34
TCF7L2 Gene Polymorphism as a Risk for Type 2 Diabetes ...
https://www.researchsquare.com/article/rs-438435/v1.pdf
Page 1/16. TCF7L2 Gene Polymorphism as a Risk for Type 2. Diabetes Mellitus and Diabetic Microvascular. Complications.
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https://www.researchsquare.com/article/rs-438435/v1.pdf
Page 1/16. TCF7L2 Gene Polymorphism as a Risk for Type 2. Diabetes Mellitus and Diabetic Microvascular. Complications.
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35
TCF7L2 Gene - GeneCards | TF7L2 Protein | TF7L2 Antibody
https://www.genecards.org/cgi-bin/carddisp.pl?gene=TCF7L2
TCF7L2 (Transcription Factor 7 Like 2) is a Protein Coding gene. Diseases associated with TCF7L2 include Type 2 Diabetes Mellitus and ...
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https://www.genecards.org/cgi-bin/carddisp.pl?gene=TCF7L2
TCF7L2 (Transcription Factor 7 Like 2) is a Protein Coding gene. Diseases associated with TCF7L2 include Type 2 Diabetes Mellitus and ...
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36
Association between TCF7L2 Genotype and Glycemic Control ...
https://www.hindawi.com/journals/ije/2013/374858/
Ren et al., “Ser 1369Ala variant in sulfonylurea receptor gene ABCC8 Is associated with antidiabetic efficacy of gliclazide in Chinese Type 2 diabetic patients, ...
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https://www.hindawi.com/journals/ije/2013/374858/
Ren et al., “Ser 1369Ala variant in sulfonylurea receptor gene ABCC8 Is associated with antidiabetic efficacy of gliclazide in Chinese Type 2 diabetic patients, ...
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37
Genetic variants of TCF7L2 gene and its coherence with ...
https://www.diabetesresearchclinicalpractice.com/article/S0168-8227(20)30893-7/fulltext
TCF7L2 is reproducibly associated with type 2 diabetes in various ethnic groups: a global meta-analysis. J Mol Med (Berl). 2007; 85: 777-782.
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https://www.diabetesresearchclinicalpractice.com/article/S0168-8227(20)30893-7/fulltext
TCF7L2 is reproducibly associated with type 2 diabetes in various ethnic groups: a global meta-analysis. J Mol Med (Berl). 2007; 85: 777-782.
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38
Whole-grain consumption and transcription factor-7-like 2 ...
https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/wholegrain-consumption-and-transcription-factor7like-2-tcf7l2-rs7903146-genediet-interaction-in-modulating-type-2-diabetes-risk/AC2E0D37000593C62CD1F934191870B3
The transcription factor-7-like 2 (TCF7L2) gene is a major susceptibility locus for type 2 diabetes (Reference Cauchi, El Achhab and Choquet , ...
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https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/wholegrain-consumption-and-transcription-factor7like-2-tcf7l2-rs7903146-genediet-interaction-in-modulating-type-2-diabetes-risk/AC2E0D37000593C62CD1F934191870B3
The transcription factor-7-like 2 (TCF7L2) gene is a major susceptibility locus for type 2 diabetes (Reference Cauchi, El Achhab and Choquet , ...
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39
Transcription Factor 7-like 2 (TCF7L2) rs7903146 ...
https://www.readcube.com/articles/10.4172%2F2165-7904.1000250
transformed the genetic landscape of type 2 diabetes susceptibility [1]. ... consequence on diabetes susceptibility in multiple populations [2]. ... linkage to T2DM ...
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https://www.readcube.com/articles/10.4172%2F2165-7904.1000250
transformed the genetic landscape of type 2 diabetes susceptibility [1]. ... consequence on diabetes susceptibility in multiple populations [2]. ... linkage to T2DM ...
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40
Human Gene TCF7L2 (uc010qro.2)
https://genome.ucsc.edu/cgi-bin/hgGene?hgg_gene=uc010qro.2&hgg_prot=uc010qro.2&hgg_chrom=chr10&hgg_start=114710008&hgg_end=114927436&hgg_type=knownGene&db=hg19&hgsid=980173019_YsJCLAWYCQ8nWAnmAoe7DY66XQjq
The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several ...
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https://genome.ucsc.edu/cgi-bin/hgGene?hgg_gene=uc010qro.2&hgg_prot=uc010qro.2&hgg_chrom=chr10&hgg_start=114710008&hgg_end=114927436&hgg_type=knownGene&db=hg19&hgsid=980173019_YsJCLAWYCQ8nWAnmAoe7DY66XQjq
The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several ...
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41
Effects of TCF7L2 rs7903146 variant on metformin response ...
https://www.bjbms.org/ojs/index.php/bjbms/article/view/4181
The response to metformin, the most commonly used drug for the treatment of type 2 diabetes (T2D), is highly variable.
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https://www.bjbms.org/ojs/index.php/bjbms/article/view/4181
The response to metformin, the most commonly used drug for the treatment of type 2 diabetes (T2D), is highly variable.
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42
Entry - *602228 - TRANSCRIPTION FACTOR 7-LIKE 2; TCF7L2
https://www.omim.org/entry/602228
TCF7L2 expression in human islets was increased 5-fold in type 2 diabetes, particularly in carriers of the TT genotype; overexpression of TCF7L2 in human islets ...
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https://www.omim.org/entry/602228
TCF7L2 expression in human islets was increased 5-fold in type 2 diabetes, particularly in carriers of the TT genotype; overexpression of TCF7L2 in human islets ...
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43
Preventing type 2 diabetes mellitus: Insights from genetic studies
https://www.mayoclinic.org/medical-professionals/endocrinology/news/preventing-type-2-diabetes-mellitus-insights-from-genetic-studies/mac-20430846
"The effect size is significant; for example, in the Diabetes Prevention Program, the TT genotype of TCF7L2 at rs7903146 conferred a 2.41-fold ...
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https://www.mayoclinic.org/medical-professionals/endocrinology/news/preventing-type-2-diabetes-mellitus-insights-from-genetic-studies/mac-20430846
"The effect size is significant; for example, in the Diabetes Prevention Program, the TT genotype of TCF7L2 at rs7903146 conferred a 2.41-fold ...
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44
Transcription Factor 7-like 2 (TCF7L2) rs7903146 ...
https://www.omicsonline.org/open-access/transcription-factor-like-tcfl-rs-polymorphism-association-with-type-diabetes-mellitus-susceptibility-2165-7904-5-250.php?aid=40114
The SNP rs7903146 in TCF7L2 is associated with an increased risk of type 2 diabetes mellitus [2,34,37-39]. The TT haplotype increases the risk of T2D in ...
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https://www.omicsonline.org/open-access/transcription-factor-like-tcfl-rs-polymorphism-association-with-type-diabetes-mellitus-susceptibility-2165-7904-5-250.php?aid=40114
The SNP rs7903146 in TCF7L2 is associated with an increased risk of type 2 diabetes mellitus [2,34,37-39]. The TT haplotype increases the risk of T2D in ...
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45
Alterations in TCF7L2 expression define its role as a key ...
https://genome.cshlp.org/content/21/9/1417.full
Genome-wide association studies (GWAS) have consistently implicated noncoding variation within the TCF7L2 locus with type 2 diabetes (T2D) ...
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https://genome.cshlp.org/content/21/9/1417.full
Genome-wide association studies (GWAS) have consistently implicated noncoding variation within the TCF7L2 locus with type 2 diabetes (T2D) ...
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46
Association between transcription factor 7-like 2 rs7903146 ...
https://journals.sagepub.com/doi/full/10.1177/1479164115598274
Grant, SF, Thorleifsson, G, Reynisdottir, I. ... Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet ...
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https://journals.sagepub.com/doi/full/10.1177/1479164115598274
Grant, SF, Thorleifsson, G, Reynisdottir, I. ... Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet ...
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47
Significant Association of Polymorphisms in the TCF7L2 Gene ...
https://pdfs.semanticscholar.org/9ba1/ae93b0aac9142a4c50d70f641da1a6537810.pdf
with a Higher Risk of Type 2 Diabetes in a Moroccan Population ... transcription factor 7-like 2 (TCF7L2) are highly associated with the ...
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https://pdfs.semanticscholar.org/9ba1/ae93b0aac9142a4c50d70f641da1a6537810.pdf
with a Higher Risk of Type 2 Diabetes in a Moroccan Population ... transcription factor 7-like 2 (TCF7L2) are highly associated with the ...
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48
TCF7L2 rs7903146 Gene Variation Is Associated with Risk of ...
https://www.hilarispublisher.com/open-access/tcf7l2-rs7903146-gene-variation-is-associated-with-risk-of-type-2-diabetesin-turkish-population-2332-0672-1000141.pdf
Type 2 diabetes (T2D) results from combination of environmental factors and genetic determinants. Transcription factor 7-like 2 (TCF7L2) genes have been ...
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https://www.hilarispublisher.com/open-access/tcf7l2-rs7903146-gene-variation-is-associated-with-risk-of-type-2-diabetesin-turkish-population-2332-0672-1000141.pdf
Type 2 diabetes (T2D) results from combination of environmental factors and genetic determinants. Transcription factor 7-like 2 (TCF7L2) genes have been ...
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49
TCF7L2 Polymorphism and Inflammation in Type II Diabetes
https://actascientific.com/ASPS/pdf/ASPS-04-0452.pdf
Keywords: Type 2 Diabetes; TCF7L2; Cycle Threshold. Though the genetic susceptibility to T2D is polygenic, with almost 50 loci identified to ...
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https://actascientific.com/ASPS/pdf/ASPS-04-0452.pdf
Keywords: Type 2 Diabetes; TCF7L2; Cycle Threshold. Though the genetic susceptibility to T2D is polygenic, with almost 50 loci identified to ...
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50
TCF7L2 plays a complex role in human adipose progenitor ...
https://www.rdm.ox.ac.uk/publications/1260035
INTRODUCTION: Non-coding genetic variation at TCF7L2 is the strongest genetic determinant of type 2 diabetes (T2D) risk in humans. TCF7L2 encodes a ...
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https://www.rdm.ox.ac.uk/publications/1260035
INTRODUCTION: Non-coding genetic variation at TCF7L2 is the strongest genetic determinant of type 2 diabetes (T2D) risk in humans. TCF7L2 encodes a ...
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51
Pivotal Role of Both TNF-α 238G/A and TCF7L2 C/T Gene ...
https://oamjms.eu/index.php/mjms/article/view/5008
Transcription factor 7-like 2 (TCF7L2) gene has been found to be one of the most risky genes for prediabetes and progression toT2DM. However, the underlying ...
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https://oamjms.eu/index.php/mjms/article/view/5008
Transcription factor 7-like 2 (TCF7L2) gene has been found to be one of the most risky genes for prediabetes and progression toT2DM. However, the underlying ...
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52
Association between the TCF7L2 rs12255372 (G/T) gene ...
https://clintransmed.springeropen.com/articles/10.1186/s40169-015-0058-1
To study the relationship between the rs12255372 (G/T) polymorphism of the transcription factor 7-like 2 (TCF7L2) and type 2 diabetes ...
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https://clintransmed.springeropen.com/articles/10.1186/s40169-015-0058-1
To study the relationship between the rs12255372 (G/T) polymorphism of the transcription factor 7-like 2 (TCF7L2) and type 2 diabetes ...
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53
Reduction in Tcf7l2 Expression Decreases Diabetic ...
https://www.ijbs.com/v08p0791.htm
Objective: The WNT signaling pathway effector gene TCF7L2 has been associated with an increased risk of type 2 diabetes. However, it remains unclear how ...
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https://www.ijbs.com/v08p0791.htm
Objective: The WNT signaling pathway effector gene TCF7L2 has been associated with an increased risk of type 2 diabetes. However, it remains unclear how ...
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54
Transcription Factor 7-Like-2 (TCF7L2) rs7903146 (C/T ...
https://d-nb.info/1224579356/34
Introduction: Type 2 diabetes mellitus (T2DM) is a metabol- ic disorder characterized by the incapability of pancreas to increase insulin ...
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https://d-nb.info/1224579356/34
Introduction: Type 2 diabetes mellitus (T2DM) is a metabol- ic disorder characterized by the incapability of pancreas to increase insulin ...
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55
Interaction analysis of gene variants of TCF7L2 and body ...
https://www.clinicalnutritionjournal.com/article/S0261-5614(19)30032-9/fulltext
Type 2 diabetes (T2D) is a complex metabolic disease with numerous risk factors, including a growing number of genetic susceptibility ...
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https://www.clinicalnutritionjournal.com/article/S0261-5614(19)30032-9/fulltext
Type 2 diabetes (T2D) is a complex metabolic disease with numerous risk factors, including a growing number of genetic susceptibility ...
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56
Prime suspect: the TCF7L2 gene and type 2 diabetes risk - Gale
https://go.gale.com/ps/i.do?id=GALE%7CA167647023&sid=googleScholar&v=2.1&it=r&linkaccess=abs&issn=00219738&p=AONE&sw=w
Transcription factor-7-like 2 (TCF7L2) is the most important type 2 diabetes susceptibility gene identified to date, with common intronic variants strongly ...
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https://go.gale.com/ps/i.do?id=GALE%7CA167647023&sid=googleScholar&v=2.1&it=r&linkaccess=abs&issn=00219738&p=AONE&sw=w
Transcription factor-7-like 2 (TCF7L2) is the most important type 2 diabetes susceptibility gene identified to date, with common intronic variants strongly ...
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57
Does TCF7L2 polymorphisms increase the risk of gestational ...
https://www.endocrine-abstracts.org/ea/0034/ea0034p270
Conclusion: The TCF7L2 polymorphism rs4506565 showed a trend towards association with gestational diabetes, when compared to the other two common polymorphisms ...
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https://www.endocrine-abstracts.org/ea/0034/ea0034p270
Conclusion: The TCF7L2 polymorphism rs4506565 showed a trend towards association with gestational diabetes, when compared to the other two common polymorphisms ...
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58
Single Nucleotide Polymorphism at rs7903146 of ...
https://asean-endocrinejournal.org/index.php/JAFES/article/view/1167
Cropano C, Santoro N, Groop L, et al. The rs7903146 variant in the TCF7L2 gene increases the risk of prediabetes/type 2 diabetes in obese ...
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https://asean-endocrinejournal.org/index.php/JAFES/article/view/1167
Cropano C, Santoro N, Groop L, et al. The rs7903146 variant in the TCF7L2 gene increases the risk of prediabetes/type 2 diabetes in obese ...
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59
Association of TCF7L2 gene polymorphisms with susceptibility ...
https://www.geneticsmr.org/articles/association-of-tcf7l2-gene-polymorphisms-with-susceptibility-to-type-2-diabetes-mellitus-in-a-chinese-hui-population.pdf
transcription factor 7-like 2 (TCF7L2) gene were strongly associated ... Key words: TCF7L2; Polymorphism; Type 2 diabetes mellitus;.
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https://www.geneticsmr.org/articles/association-of-tcf7l2-gene-polymorphisms-with-susceptibility-to-type-2-diabetes-mellitus-in-a-chinese-hui-population.pdf
transcription factor 7-like 2 (TCF7L2) gene were strongly associated ... Key words: TCF7L2; Polymorphism; Type 2 diabetes mellitus;.
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60
Association of TCF7L2 gene variants with low GAD ...
https://www.siditalia.it/images/Documenti/nirad/6.pdf
high (> 32 units) GADA titre, 620 subjects with Type 2 diabetes [from the Non-Insulin Requiring Autoimmune Diabetes. (NIRAD) study cohort of 5330 subjects] in ...
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https://www.siditalia.it/images/Documenti/nirad/6.pdf
high (> 32 units) GADA titre, 620 subjects with Type 2 diabetes [from the Non-Insulin Requiring Autoimmune Diabetes. (NIRAD) study cohort of 5330 subjects] in ...
→ Check Latest Keyword Rankings ←
61
Association Between Type 2 Diabetes Mellitus and TCF7L2 ...
https://www.ajol.info/index.php/ejhm/article/view/223970/211285
Association Between Type 2 Diabetes Mellitus and TCF7L2 And. FTO Gene Variants Among Upper Egyptian Population. M. Hossam Maghraby1, Refat Fathy1, ...
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https://www.ajol.info/index.php/ejhm/article/view/223970/211285
Association Between Type 2 Diabetes Mellitus and TCF7L2 And. FTO Gene Variants Among Upper Egyptian Population. M. Hossam Maghraby1, Refat Fathy1, ...
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62
Type 2 Diabetes TCF7L2 Risk Genotypes Alter Birth Weight
https://www.cell.com/ajhg/pdf/S0002-9297(07)61032-5.pdf
assess the role of the recently described type 2 diabetes gene TCF7L2 in birth weight. We genotyped the polymorphism.
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https://www.cell.com/ajhg/pdf/S0002-9297(07)61032-5.pdf
assess the role of the recently described type 2 diabetes gene TCF7L2 in birth weight. We genotyped the polymorphism.
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63
Interaction of Diet/Lifestyle Intervention and TCF7L2 Genotype ...
https://spj.sciencemag.org/journals/hds/2021/9897048/
Objective. The strongest locus which associated with type 2 diabetes (T2D) by the common variant rs7903146 is the transcription factor 7-like 2 gene (TCF7L2).
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https://spj.sciencemag.org/journals/hds/2021/9897048/
Objective. The strongest locus which associated with type 2 diabetes (T2D) by the common variant rs7903146 is the transcription factor 7-like 2 gene (TCF7L2).
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64
TCF7L2 gene rs7903146 polymorphism is observed ... - OAText
https://www.oatext.com/TCF7L2-gene-rs7903146-polymorphism-is-observed-in-gestational-diabetes-mellitus-in-Bangladesh.php
TCF7L2 seems to be required to maintain glucose stimulated insulin secretion and β-cell survival as is observed by the fact that its deletion in human islets ...
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https://www.oatext.com/TCF7L2-gene-rs7903146-polymorphism-is-observed-in-gestational-diabetes-mellitus-in-Bangladesh.php
TCF7L2 seems to be required to maintain glucose stimulated insulin secretion and β-cell survival as is observed by the fact that its deletion in human islets ...
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65
The correlation between polymorphism of TCF7L2 gene and ...
https://iopscience.iop.org/article/10.1088/1742-6596/1321/3/032029
The correlation between polymorphism of TCF7L2 gene and the incidence of type 2 Diabetes in Asian: a meta analysis. A Yuniastuti1, R S Iswari1 and R Susanti ...
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https://iopscience.iop.org/article/10.1088/1742-6596/1321/3/032029
The correlation between polymorphism of TCF7L2 gene and the incidence of type 2 Diabetes in Asian: a meta analysis. A Yuniastuti1, R S Iswari1 and R Susanti ...
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66
Transcription factor 7-like 2 (TCF7L2) gene polymorphisms ...
https://dergipark.org.tr/tr/download/article-file/733394
Transcription factor 7-like 2 (TCF7L2) gene polymorphisms are strong predictors of type 2 diabetes among nonobese diabetics in the Turkish population.
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https://dergipark.org.tr/tr/download/article-file/733394
Transcription factor 7-like 2 (TCF7L2) gene polymorphisms are strong predictors of type 2 diabetes among nonobese diabetics in the Turkish population.
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67
Worldwide distribution of type II diabetes-associated TCF7L2 ...
https://read.qxmd.com/read/21898192/worldwide-distribution-of-type-ii-diabetes-associated-tcf7l2-snps-evidence-for-stratification-in-europe
Type II diabetes is a multifactorial disease with a complex etiology. Numerous genes have been implicated in disease pathogenesis.
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https://read.qxmd.com/read/21898192/worldwide-distribution-of-type-ii-diabetes-associated-tcf7l2-snps-evidence-for-stratification-in-europe
Type II diabetes is a multifactorial disease with a complex etiology. Numerous genes have been implicated in disease pathogenesis.
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68
(PDF) Transcription factor 7-like 2 (TCF7L2): a culprit gene in ...
https://www.researchgate.net/publication/356190883_Transcription_factor_7-like_2_TCF7L2_a_culprit_gene_in_Type_2_Diabetes_Mellitus
In 2006 an important step while finding genetic causes of diabetes type 2 was identification of transcription factor 7-like 2 (TCF7L2) gene ...
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https://www.researchgate.net/publication/356190883_Transcription_factor_7-like_2_TCF7L2_a_culprit_gene_in_Type_2_Diabetes_Mellitus
In 2006 an important step while finding genetic causes of diabetes type 2 was identification of transcription factor 7-like 2 (TCF7L2) gene ...
→ Check Latest Keyword Rankings ←
69
Is Type 2 Diabetes Genetic? Environmental Factors and More
https://www.healthline.com/health/type-2-diabetes/genetics
the production and regulation of insulin; how glucose levels are sensed in the body. Genes associated with type 2 diabetes risk include: TCF7L2, which affects ...
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https://www.healthline.com/health/type-2-diabetes/genetics
the production and regulation of insulin; how glucose levels are sensed in the body. Genes associated with type 2 diabetes risk include: TCF7L2, which affects ...
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70
Role of the type 2 diabetes GWAS gene TCF7L2 in LKB1-mediated ...
https://www.easd.org/virtualmeeting/home.html#!resources/role-of-the-type-2-diabetes-gwas-gene-tcf7l2-in-lkb1-mediated-regulation-of-insulin-secretion-in-the-murine-beta-cell-05bf72ac-8414-4c3a-9a72-ca371fcd275f
Role of the type 2 diabetes GWAS gene TCF7L2 in LKB1-mediated regulation of insulin secretion in the murine beta cell. ePoster # 341.
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https://www.easd.org/virtualmeeting/home.html#!resources/role-of-the-type-2-diabetes-gwas-gene-tcf7l2-in-lkb1-mediated-regulation-of-insulin-secretion-in-the-murine-beta-cell-05bf72ac-8414-4c3a-9a72-ca371fcd275f
Role of the type 2 diabetes GWAS gene TCF7L2 in LKB1-mediated regulation of insulin secretion in the murine beta cell. ePoster # 341.
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71
Overview of Type 2 Diabetes and Prediabetes - YouTube
https://www.youtube.com/watch?v=S-ssBDD1-ZI
University of California Television (UCTV)
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https://www.youtube.com/watch?v=S-ssBDD1-ZI
University of California Television (UCTV)
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72
Yearbook of Pediatric Endocrinology 2007: Endorsed by the ...
https://books.google.com/books?id=2MJ_-B0ka2gC&pg=PA149&lpg=PA149&dq=type+2+diabetes+tcf7l2&source=bl&ots=PVrVsEsvWH&sig=ACfU3U0NgaEdNgxnL45qDh7c90iKt1ngyA&hl=en&sa=X&ved=2ahUKEwi5w6PE69z7AhXwnXIEHXrHBBQQ6AF6BQiuAhAD
New paradigms – TCF7L2 in T2DM Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution Helgason A, Palsson S, Thorleifsson G, ...
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https://books.google.com/books?id=2MJ_-B0ka2gC&pg=PA149&lpg=PA149&dq=type+2+diabetes+tcf7l2&source=bl&ots=PVrVsEsvWH&sig=ACfU3U0NgaEdNgxnL45qDh7c90iKt1ngyA&hl=en&sa=X&ved=2ahUKEwi5w6PE69z7AhXwnXIEHXrHBBQQ6AF6BQiuAhAD
New paradigms – TCF7L2 in T2DM Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution Helgason A, Palsson S, Thorleifsson G, ...
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73
The Epidemiology of Diabetes Mellitus
https://books.google.com/books?id=sZODtZoWvlEC&pg=PA101&lpg=PA101&dq=type+2+diabetes+tcf7l2&source=bl&ots=m6kq9Ijph-&sig=ACfU3U0rxTZdltEQLdFkLQAU-i2hfuRieQ&hl=en&sa=X&ved=2ahUKEwi5w6PE69z7AhXwnXIEHXrHBBQQ6AF6BQivAhAD
(2005) Genetic prediction of type 2 diabetes. PloS Medicine, 2 ... 2 (TCF7L2) [39]. TCF7L2 encodes for a transcription factor involved in Wnt signaling.
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https://books.google.com/books?id=sZODtZoWvlEC&pg=PA101&lpg=PA101&dq=type+2+diabetes+tcf7l2&source=bl&ots=m6kq9Ijph-&sig=ACfU3U0rxTZdltEQLdFkLQAU-i2hfuRieQ&hl=en&sa=X&ved=2ahUKEwi5w6PE69z7AhXwnXIEHXrHBBQQ6AF6BQivAhAD
(2005) Genetic prediction of type 2 diabetes. PloS Medicine, 2 ... 2 (TCF7L2) [39]. TCF7L2 encodes for a transcription factor involved in Wnt signaling.
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74
Yearbook of Pediatric Endocrinology 2008
https://books.google.com/books?id=8FTtji7pd2sC&pg=PA160&lpg=PA160&dq=type+2+diabetes+tcf7l2&source=bl&ots=-kz54t7S_L&sig=ACfU3U10YEclofOr8RfFcp2LBn0Uj3kTsw&hl=en&sa=X&ved=2ahUKEwi5w6PE69z7AhXwnXIEHXrHBBQQ6AF6BQioAhAD
New genee Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes Lyssenko V, Lupi R, Marchetti P, Del Guerra S, ...
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https://books.google.com/books?id=8FTtji7pd2sC&pg=PA160&lpg=PA160&dq=type+2+diabetes+tcf7l2&source=bl&ots=-kz54t7S_L&sig=ACfU3U10YEclofOr8RfFcp2LBn0Uj3kTsw&hl=en&sa=X&ved=2ahUKEwi5w6PE69z7AhXwnXIEHXrHBBQQ6AF6BQioAhAD
New genee Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes Lyssenko V, Lupi R, Marchetti P, Del Guerra S, ...
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75
Principles of Pharmacogenetics and Pharmacogenomics
https://books.google.com/books?id=7EAhAwAAQBAJ&pg=PA153&lpg=PA153&dq=type+2+diabetes+tcf7l2&source=bl&ots=PaZUFempTR&sig=ACfU3U1ojQC08MT-u3aXrW2K2da_I5xDug&hl=en&sa=X&ved=2ahUKEwi5w6PE69z7AhXwnXIEHXrHBBQQ6AF6BQipAhAD
Prime suspect: the TCF7L2 gene and type 2 diabetes risk. J Clin Invest. 2007;117:2077–9. Lyssenko V, Lupi R, Marchetti P, Del Guerra S, OrhoMelander M, ...
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https://books.google.com/books?id=7EAhAwAAQBAJ&pg=PA153&lpg=PA153&dq=type+2+diabetes+tcf7l2&source=bl&ots=PaZUFempTR&sig=ACfU3U1ojQC08MT-u3aXrW2K2da_I5xDug&hl=en&sa=X&ved=2ahUKEwi5w6PE69z7AhXwnXIEHXrHBBQQ6AF6BQipAhAD
Prime suspect: the TCF7L2 gene and type 2 diabetes risk. J Clin Invest. 2007;117:2077–9. Lyssenko V, Lupi R, Marchetti P, Del Guerra S, OrhoMelander M, ...
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76
GWAS of Type 2 Diabetes
https://mmg-233-2014-genetics-genomics.fandom.com/wiki/GWAS_of_Type_2_Diabetes
This analysis confirmed the association of TCF7L2, which is on chromosome 10. They also identified 7 mroe SNPs representing 4 new T2DM loci. The most ...
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https://mmg-233-2014-genetics-genomics.fandom.com/wiki/GWAS_of_Type_2_Diabetes
This analysis confirmed the association of TCF7L2, which is on chromosome 10. They also identified 7 mroe SNPs representing 4 new T2DM loci. The most ...
→ Check Latest Keyword Rankings ←
77
Cardiac Autonomic Neuropathy in Type 1 and 2 Diabetes - DOI
https://doi.org/10.1016/j.clinthera.2022.09.002
However, in type 2 diabetes, multifactorial risk factors, including obesity, hypertension, and hyperlipidemia, are associated with the development of CAN.
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https://doi.org/10.1016/j.clinthera.2022.09.002
However, in type 2 diabetes, multifactorial risk factors, including obesity, hypertension, and hyperlipidemia, are associated with the development of CAN.
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78
Measuring gene expression changes over time may help ...
https://hscweb3.hsc.usf.edu/blog/2021/06/04/measuring-gene-expression-changes-over-time-may-help-predict-t1d-progression-lead-to-earlier-diagnosis/
TAMPA, Fla. (June 4, 2021) — Type 1 diabetes mellitis (T1D) is an autoimmune disease in which a misdirected immune system gradually destroys ...
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https://hscweb3.hsc.usf.edu/blog/2021/06/04/measuring-gene-expression-changes-over-time-may-help-predict-t1d-progression-lead-to-earlier-diagnosis/
TAMPA, Fla. (June 4, 2021) — Type 1 diabetes mellitis (T1D) is an autoimmune disease in which a misdirected immune system gradually destroys ...
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79
Ποια γονίδια σχετίζονται με τη Διατροφή; - medNutrition
https://www.mednutrition.gr/portal/lifestyle/diatrofi/17340-poia-gonidia-sxetizontai-me-ti-diatrofi
Ο TCF7L2 (Transcription factor 7 like 2), παράγεται από το γονίδιο TCF7L2 και είναι ένας μεταγραφικός παράγοντας, ο οποίος έχει συσχετιστεί ...
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https://www.mednutrition.gr/portal/lifestyle/diatrofi/17340-poia-gonidia-sxetizontai-me-ti-diatrofi
Ο TCF7L2 (Transcription factor 7 like 2), παράγεται από το γονίδιο TCF7L2 και είναι ένας μεταγραφικός παράγοντας, ο οποίος έχει συσχετιστεί ...
→ Check Latest Keyword Rankings ←
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