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Google Keyword Rankings for : mmp 13 arthritis
1
Overview of MMP-13 as a Promising Target for the Treatment ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916132/
Osteoarthritis (OA) is an age-related degenerative disease, which is characterized by chronic joint pain, inflammation and the damage of joint cartilage.
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916132/
Osteoarthritis (OA) is an age-related degenerative disease, which is characterized by chronic joint pain, inflammation and the damage of joint cartilage.
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2
Effect of the oral application of a highly selective MMP-13 ...
https://ard.bmj.com/content/69/5/898
Objective To evaluate the decrease of cartilage destruction by a novel orally active and specific matrix metalloproteinase 13 (MMP-13) inhibitor in three ...
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https://ard.bmj.com/content/69/5/898
Objective To evaluate the decrease of cartilage destruction by a novel orally active and specific matrix metalloproteinase 13 (MMP-13) inhibitor in three ...
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3
Indole Inhibitors of MMP-13 for Arthritic Disorders | ACS Omega
https://pubs.acs.org/doi/10.1021/acsomega.1c01320
(10) MMP-13 inhibition is beneficial in in vitro and in vivo models of arthritis, prompting several drug discovery campaigns aimed at developing ...
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https://pubs.acs.org/doi/10.1021/acsomega.1c01320
(10) MMP-13 inhibition is beneficial in in vitro and in vivo models of arthritis, prompting several drug discovery campaigns aimed at developing ...
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4
Potential Value of Matrix Metalloproteinase-13 as a Biomarker ...
https://www.frontiersin.org/articles/10.3389/fsurg.2021.750047/full
Background: Emerging knowledge has highlighted the role of matrix metalloproteinase (MMP)-13 in osteoarthritis (OA); however, the suitability of MMP-13 as a ...
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https://www.frontiersin.org/articles/10.3389/fsurg.2021.750047/full
Background: Emerging knowledge has highlighted the role of matrix metalloproteinase (MMP)-13 in osteoarthritis (OA); however, the suitability of MMP-13 as a ...
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5
MMP-13 in Osteoarthritis Treatment - Encyclopedia.pub
https://encyclopedia.pub/10322
Matrix metalloproteinase-13 (MMP-13) is the primary MMP involved in cartilage degradation through its particular ability to cleave type II collagen.
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https://encyclopedia.pub/10322
Matrix metalloproteinase-13 (MMP-13) is the primary MMP involved in cartilage degradation through its particular ability to cleave type II collagen.
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6
MMP-13 is constitutively produced in human chondrocytes ...
https://www.sciencedirect.com/science/article/pii/S0945053X16300312
Matrix metalloproteinase 13 (MMP-13) degrades collagenous extracellular matrix and its aberrant activity associates with diseases such as arthritis, cancer, ...
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https://www.sciencedirect.com/science/article/pii/S0945053X16300312
Matrix metalloproteinase 13 (MMP-13) degrades collagenous extracellular matrix and its aberrant activity associates with diseases such as arthritis, cancer, ...
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7
Matrix metalloproteinase‑13, NF‑κB p65 and interleukin‑1β ...
https://www.spandidos-publications.com/10.3892/etm.2020.8618
Osteoarthritis (OA) is the most prevalent type of arthritis, and it is characterized by a progressive degradation of articular cartilage, new ...
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https://www.spandidos-publications.com/10.3892/etm.2020.8618
Osteoarthritis (OA) is the most prevalent type of arthritis, and it is characterized by a progressive degradation of articular cartilage, new ...
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8
Matrix metalloproteinase‐13 is fully activated by neutrophil ...
https://febs.onlinelibrary.wiley.com/doi/10.1111/febs.16127
Neutrophil elastase (NE) is a well-described proteoglycan-degrading enzyme which is historically associated with inflammatory arthritis, but ...
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https://febs.onlinelibrary.wiley.com/doi/10.1111/febs.16127
Neutrophil elastase (NE) is a well-described proteoglycan-degrading enzyme which is historically associated with inflammatory arthritis, but ...
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9
Matrix metallopeptidase 13 - Wikipedia
https://en.wikipedia.org/wiki/Matrix_metallopeptidase_13
During embryonic development, MMP-13 is expressed in the skeleton as required for restructuring the collagen matrix for bone mineralization. In pathological ...
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https://en.wikipedia.org/wiki/Matrix_metallopeptidase_13
During embryonic development, MMP-13 is expressed in the skeleton as required for restructuring the collagen matrix for bone mineralization. In pathological ...
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10
Targeting articular Mmp13 in OA - Nature
https://www.nature.com/articles/s41584-021-00696-x
... joints and promote localized downregulation of Mmp13 expression represent progress towards a disease-modifying osteoarthritis drug.
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https://www.nature.com/articles/s41584-021-00696-x
... joints and promote localized downregulation of Mmp13 expression represent progress towards a disease-modifying osteoarthritis drug.
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11
Regulation of MMP-13 expression by RUNX2 and FGF2 in ...
https://www.oarsijournal.com/article/S1063-4584(04)00161-X/fulltext
Introduction · Qualitative and quantitative changes in chondrocyte gene expression contribute to the onset and progression of osteoarthritis (OA). · MMP-13 is ...
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https://www.oarsijournal.com/article/S1063-4584(04)00161-X/fulltext
Introduction · Qualitative and quantitative changes in chondrocyte gene expression contribute to the onset and progression of osteoarthritis (OA). · MMP-13 is ...
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12
Medline ® Abstract for Reference 72 of 'Pathogenesis of ...
https://www.uptodate.com/contents/pathogenesis-of-rheumatoid-arthritis/abstract/72
Matrix metalloproteinase (MMP)-13 may contribute to the breakdown of articular cartilage during arthritis. Here, we found that SDF-1alpha increased the ...
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https://www.uptodate.com/contents/pathogenesis-of-rheumatoid-arthritis/abstract/72
Matrix metalloproteinase (MMP)-13 may contribute to the breakdown of articular cartilage during arthritis. Here, we found that SDF-1alpha increased the ...
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13
Serum Matrix Metalloproteinase 13 As a Translational Marker ...
https://acrabstracts.org/abstract/serum-matrix-metalloproteinase-13-as-a-translational-marker-for-efficacy-of-anti-arthritic-treatments-in-rat-collagen-induced-arthritis-and-mouse-model-of-lipopolysaccharide-induced-bone-resorption/
Serum Matrix Metalloproteinase 13 As a Translational Marker For Efficacy Of Anti-Arthritic Treatments In Rat Collagen Induced Arthritis and Mouse Model Of ...
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https://acrabstracts.org/abstract/serum-matrix-metalloproteinase-13-as-a-translational-marker-for-efficacy-of-anti-arthritic-treatments-in-rat-collagen-induced-arthritis-and-mouse-model-of-lipopolysaccharide-induced-bone-resorption/
Serum Matrix Metalloproteinase 13 As a Translational Marker For Efficacy Of Anti-Arthritic Treatments In Rat Collagen Induced Arthritis and Mouse Model Of ...
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14
Novel selective MMP-13 inhibitors reduce collagen ...
https://link.springer.com/article/10.1007/s00011-009-0112-9
MMP-13 is highly upregulated in arthritis and therefore strongly implicated in the pathogenesis of osteoarthritis (OA).
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https://link.springer.com/article/10.1007/s00011-009-0112-9
MMP-13 is highly upregulated in arthritis and therefore strongly implicated in the pathogenesis of osteoarthritis (OA).
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15
Postnatal expression in hyaline cartilage of constitutively ... - JCI
https://www.jci.org/articles/view/10564
... active human collagenase-3 (MMP-13) induces osteoarthritis in mice ... Degenerative joint diseases including osteoarthritis (OA) are common, ...
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https://www.jci.org/articles/view/10564
... active human collagenase-3 (MMP-13) induces osteoarthritis in mice ... Degenerative joint diseases including osteoarthritis (OA) are common, ...
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16
The expression levels of interleukin-6 (IL-6), IL-12, and matrix ...
https://e-century.us/files/ijcem/13/2/ijcem0099623.pdf
matrix metalloproteinase-13 (MMP-13) in the synovial fluid and synovium in hip osteoarthritis and their relationship with disease progression.
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https://e-century.us/files/ijcem/13/2/ijcem0099623.pdf
matrix metalloproteinase-13 (MMP-13) in the synovial fluid and synovium in hip osteoarthritis and their relationship with disease progression.
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17
13 Synthesis Induced by IL-1β in Chondrocytes from Mice ...
https://www.jimmunol.org/content/185/10/6244.full
Abstract. Joint destruction in arthritis is in part due to the induction of matrix metalloproteinase (MMP) expression and their inhibitors, ...
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https://www.jimmunol.org/content/185/10/6244.full
Abstract. Joint destruction in arthritis is in part due to the induction of matrix metalloproteinase (MMP) expression and their inhibitors, ...
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18
A Tale of Two Joints: The Role of Matrix Metalloproteases in ...
https://www.hindawi.com/journals/dm/2016/4895050/
This attests to their utility as major biomarkers for osteoarthritis and mediators of joint destruction. It is worthy to note that MMP-13 is most notably ...
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https://www.hindawi.com/journals/dm/2016/4895050/
This attests to their utility as major biomarkers for osteoarthritis and mediators of joint destruction. It is worthy to note that MMP-13 is most notably ...
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19
Suppression of MMP-13 Expression in Arthritis by Pomegranate
https://grantome.com/grant/NIH/R01-AT005520-02
Osteoarthritis (OA) is the most common musculoskeletal disorder characterized by cartilage degradation and joint inflammation. Currently the only effective ...
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https://grantome.com/grant/NIH/R01-AT005520-02
Osteoarthritis (OA) is the most common musculoskeletal disorder characterized by cartilage degradation and joint inflammation. Currently the only effective ...
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20
Selective MMP-13 Inhibitors: Promising Agents for the ...
https://www.eurekaselect.com/168412/article
Osteoarthritis (OA) is an age-related degenerative disease, which is characterized by chronic joint pain, inflammation and the damage of joint cartilage.
→ Check Latest Keyword Rankings ←
https://www.eurekaselect.com/168412/article
Osteoarthritis (OA) is an age-related degenerative disease, which is characterized by chronic joint pain, inflammation and the damage of joint cartilage.
→ Check Latest Keyword Rankings ←
21
Clinical significance of serum levels of matrix ...
https://academic.oup.com/rheumatology/article/45/3/303/1788545
Matrix metalloproteinase-13 is a member of the collagenase family, ... The expression of MMP-13 has been well studied in cancer and arthritic diseases.
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https://academic.oup.com/rheumatology/article/45/3/303/1788545
Matrix metalloproteinase-13 is a member of the collagenase family, ... The expression of MMP-13 has been well studied in cancer and arthritic diseases.
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22
MMP-13 expression in joints during arthritis development. (A)...
https://www.researchgate.net/figure/MMP-13-expression-in-joints-during-arthritis-development-A-Semi-quantitative_fig1_259473125
**P <0.01. from publication: Collagenase-3 (MMP-13) deficiency protects C57BL/6 mice from antibody-induced arthritis | Matrix metalloproteinases (MMPs) are ...
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https://www.researchgate.net/figure/MMP-13-expression-in-joints-during-arthritis-development-A-Semi-quantitative_fig1_259473125
**P <0.01. from publication: Collagenase-3 (MMP-13) deficiency protects C57BL/6 mice from antibody-induced arthritis | Matrix metalloproteinases (MMPs) are ...
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23
Cytokine-induced MMP13 Expression in Human ...
https://www.jbc.org/article/S0021-9258(20)36695-3/pdf
(ECM) by the collagenase matrix metalloproteinase 13. (MMP13) represents a key event in osteoarthritis (OA) progres-.
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https://www.jbc.org/article/S0021-9258(20)36695-3/pdf
(ECM) by the collagenase matrix metalloproteinase 13. (MMP13) represents a key event in osteoarthritis (OA) progres-.
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24
Protein kinase D3 modulates MMP1 and MMP13 expression ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0195864
The progression of joint diseases such as rheumatoid arthritis (RA) and osteoarthritis (OA) is associated with inflammation, whereby ...
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https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0195864
The progression of joint diseases such as rheumatoid arthritis (RA) and osteoarthritis (OA) is associated with inflammation, whereby ...
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25
New insights on the MMP-13 regulatory network in the ...
https://d-nb.info/115020446X/34
Keywords: Matrix metalloproteinases, MMP-13, Osteoarthritis, Non-coding RNA, DNA methylation, Autophagy. Background. Osteoarthritis (OA) is the most common ...
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https://d-nb.info/115020446X/34
Keywords: Matrix metalloproteinases, MMP-13, Osteoarthritis, Non-coding RNA, DNA methylation, Autophagy. Background. Osteoarthritis (OA) is the most common ...
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26
Association of IL-6, IL-8, MMP-13 gene polymorphisms with ...
https://portlandpress.com/bioscirep/article/39/2/BSR20181346/110926/Association-of-IL-6-IL-8-MMP-13-gene-polymorphisms
... IL-8 rs4073 (-251T>A), and matrix metalloproteinase-13 (MMP-13) rs2252070 (-77G>A) gene polymorphisms and knee osteoarthritis (KOA) susceptibility in ...
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https://portlandpress.com/bioscirep/article/39/2/BSR20181346/110926/Association-of-IL-6-IL-8-MMP-13-gene-polymorphisms
... IL-8 rs4073 (-251T>A), and matrix metalloproteinase-13 (MMP-13) rs2252070 (-77G>A) gene polymorphisms and knee osteoarthritis (KOA) susceptibility in ...
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27
1,25-dihydroxyvitamin D3 Activates MMP13 Gene Expression ...
https://www.ijbs.com/v09p0649.htm
Osteoarthritis (OA) is the most prevalent degenerative joint disease. The highly regulated balance of matrix synthesis and degradation is disrupted in OA, ...
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https://www.ijbs.com/v09p0649.htm
Osteoarthritis (OA) is the most prevalent degenerative joint disease. The highly regulated balance of matrix synthesis and degradation is disrupted in OA, ...
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28
Structural Basis for the Highly Selective Inhibition of MMP-13
http://www.cell.com/chemistry-biology/pdf/S1074-5521(04)00339-4.pdf
MMP-13 reveal a novel binding mode characterized by chronic toxicity resulting from metabolic activation of ... mathoid arthritis and osteoarthritis [3].
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http://www.cell.com/chemistry-biology/pdf/S1074-5521(04)00339-4.pdf
MMP-13 reveal a novel binding mode characterized by chronic toxicity resulting from metabolic activation of ... mathoid arthritis and osteoarthritis [3].
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29
Journal of Biomolecular Structure and Dynamics
https://www.tandfonline.com/doi/abs/10.1080/07391102.2019.1651221
Osteoarthritis (OA) is the most common form of arthritis with no available ... Matrix metalloproteinase 13 (MMP-13) is vital for OA pro...
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https://www.tandfonline.com/doi/abs/10.1080/07391102.2019.1651221
Osteoarthritis (OA) is the most common form of arthritis with no available ... Matrix metalloproteinase 13 (MMP-13) is vital for OA pro...
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30
Matrix-targeted Nanoparticles for MMP13 RNA Interference ...
https://www.biorxiv.org/content/10.1101/2020.01.30.925321v1.full
Osteoarthritis (OA) is a chronic degenerative disease affecting joints and their surrounding tissues. Initial symptoms include pain and loss of ...
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https://www.biorxiv.org/content/10.1101/2020.01.30.925321v1.full
Osteoarthritis (OA) is a chronic degenerative disease affecting joints and their surrounding tissues. Initial symptoms include pain and loss of ...
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31
roles of inflammatory and anabolic cytokines in cartilage
https://www.ecmjournal.org/papers/vol021/pdf/v021a16.pdf
osteoarthritis, and aging may lead to more effective ... upregulate MMP-13 and suppress type II collagen gene. (COL2A1) expression.
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https://www.ecmjournal.org/papers/vol021/pdf/v021a16.pdf
osteoarthritis, and aging may lead to more effective ... upregulate MMP-13 and suppress type II collagen gene. (COL2A1) expression.
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32
Natural Products as Sources of Novel Drug Candidates for the ...
https://www.biomolther.org/journal/view.html?uid=1161&vmd=Full
It suppressed the expression of MMPs including MMP-13, MMP-3, and MMP-1. ... of cartilage by MMP-13, MMP-9, and MMP-13 and inflammation in arthritis by ...
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https://www.biomolther.org/journal/view.html?uid=1161&vmd=Full
It suppressed the expression of MMPs including MMP-13, MMP-3, and MMP-1. ... of cartilage by MMP-13, MMP-9, and MMP-13 and inflammation in arthritis by ...
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33
Role of MMPs in Disease Progression - Chondrex, Inc.
https://www.chondrex.com/blog/rols-of-mmps-in-disease
Continue reading to learn more about MMPs in osteoarthritis, ... Overexpression of MMP-13 by chondrocytes in articular cartilage is also associated with the ...
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https://www.chondrex.com/blog/rols-of-mmps-in-disease
Continue reading to learn more about MMPs in osteoarthritis, ... Overexpression of MMP-13 by chondrocytes in articular cartilage is also associated with the ...
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34
Development of a selective matrix metalloproteinase 13 (MMP ...
https://europepmc.org/article/med/34245949
Osteoarthritis (OA) is a chronic disorder that causes damage to the cartilage and surrounding tissues and is characterized by pain, stiffness, ...
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https://europepmc.org/article/med/34245949
Osteoarthritis (OA) is a chronic disorder that causes damage to the cartilage and surrounding tissues and is characterized by pain, stiffness, ...
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35
Activation of the P38/CREB/MMP13 axis is associated with ...
https://www.dovepress.com/activation-of-the-p38crebmmp13-axis-is-associated-with-osteoarthritis-peer-reviewed-fulltext-article-DDDT
Purposes: Osteoarthritis (OA) is a common joint disease characterized by the degradation of articular cartilage and joint inflammation.
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https://www.dovepress.com/activation-of-the-p38crebmmp13-axis-is-associated-with-osteoarthritis-peer-reviewed-fulltext-article-DDDT
Purposes: Osteoarthritis (OA) is a common joint disease characterized by the degradation of articular cartilage and joint inflammation.
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36
Transcriptional regulation of collagenase (MMP-1, MMP-13 ...
https://digitalcommons.dartmouth.edu/cgi/viewcontent.cgi?article=5250&context=facoa
MMP-13) genes in arthritis: Integration of complex signaling pathways for the recruitment of gene- specific transcription factors" (2002).
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https://digitalcommons.dartmouth.edu/cgi/viewcontent.cgi?article=5250&context=facoa
MMP-13) genes in arthritis: Integration of complex signaling pathways for the recruitment of gene- specific transcription factors" (2002).
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37
PRIME PubMed | Joint diseases and matrix metalloproteinases: a ...
https://www.unboundmedicine.com/medline/citation/18289056/Joint_diseases_and_matrix_metalloproteinases:_a_role_for_MMP_13_
MMP-13 is expressed by chondrocytes and synovial cells in human OA and RA and is ... these compounds in clinical trials for the treatment of arthritis.
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https://www.unboundmedicine.com/medline/citation/18289056/Joint_diseases_and_matrix_metalloproteinases:_a_role_for_MMP_13_
MMP-13 is expressed by chondrocytes and synovial cells in human OA and RA and is ... these compounds in clinical trials for the treatment of arthritis.
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38
MMP-13 Inhibitory Activity of Thirteen Selected Plant Species ...
https://scialert.net/fulltext/?doi=ijp.2008.202.207
Both of curcumin and rosmarinic acid exhibited excellent MMP-13 inhibitory ... osteoarthritis, rheumatoid arthritis and many inflammatory diseases (Clark ...
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https://scialert.net/fulltext/?doi=ijp.2008.202.207
Both of curcumin and rosmarinic acid exhibited excellent MMP-13 inhibitory ... osteoarthritis, rheumatoid arthritis and many inflammatory diseases (Clark ...
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39
2OW9: Crystal structure analysis of the MMP13 ... - RCSB PDB
https://www.rcsb.org/structure/2ow9
Excess MMP13 activity causes cartilage degradation in osteoarthritis, making this protease an attractive therapeutic target ...
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https://www.rcsb.org/structure/2ow9
Excess MMP13 activity causes cartilage degradation in osteoarthritis, making this protease an attractive therapeutic target ...
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40
Brasil - Association between matrix metalloproteinase-1 (MMP ...
https://www.scielo.br/j/bjmbr/a/WTpsMn8fNc5GWwLy73gDSFk/?lang=en
Matrix metalloproteinase-1; Rheumatoid arthritis; Knee osteoarthritis; ... on the MMP-13 regulatory network in the pathogenesis of early osteoarthritis.
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https://www.scielo.br/j/bjmbr/a/WTpsMn8fNc5GWwLy73gDSFk/?lang=en
Matrix metalloproteinase-1; Rheumatoid arthritis; Knee osteoarthritis; ... on the MMP-13 regulatory network in the pathogenesis of early osteoarthritis.
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41
Association of Matrix Metalloproteinase (MMP) Gene ... - Cureus
https://www.cureus.com/articles/72022-association-of-matrix-metalloproteinase-mmp-gene-polymorphisms-with-knee-osteoarthritis-a-review-of-the-literature
Osteoarthritis (OA) is one of the leading causes of pain and ... Collagen is broken down mainly by MMP-13 and secondarily by MMP-2, MMP-7, ...
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https://www.cureus.com/articles/72022-association-of-matrix-metalloproteinase-mmp-gene-polymorphisms-with-knee-osteoarthritis-a-review-of-the-literature
Osteoarthritis (OA) is one of the leading causes of pain and ... Collagen is broken down mainly by MMP-13 and secondarily by MMP-2, MMP-7, ...
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42
Prospects for treating osteoarthritis - SAGE Journals
https://journals.sagepub.com/doi/abs/10.1177/2040622312454157
(2010) Novel selective MMP-13 inhibitors reduce collagen degradation in bovine articular and human osteoarthritis cartilage explants.
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https://journals.sagepub.com/doi/abs/10.1177/2040622312454157
(2010) Novel selective MMP-13 inhibitors reduce collagen degradation in bovine articular and human osteoarthritis cartilage explants.
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43
Effect of the oral application of a highly selective ... - ProQuest
https://search.proquest.com/openview/eba48b29e2ddf6da654edac5ee5433b8/1?pq-origsite=gscholar&cbl=2041045
The SCID mouse co-implantation model of RA, the collagen-induced arthritis (CIA) model in mice and the antigen-induced arthritis model (AIA) in rabbits were ...
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https://search.proquest.com/openview/eba48b29e2ddf6da654edac5ee5433b8/1?pq-origsite=gscholar&cbl=2041045
The SCID mouse co-implantation model of RA, the collagen-induced arthritis (CIA) model in mice and the antigen-induced arthritis model (AIA) in rabbits were ...
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44
Analysis of The Relationship Between Rela Gene Expression ...
https://oamjms.eu/index.php/mjms/article/download/oamjms.2019.135/2990
and MMP-13 gene expression in osteoarthritis synoviocytes after Mesenchymal Stem Cell Wharton Jelly (r = 0.662). Introduction.
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https://oamjms.eu/index.php/mjms/article/download/oamjms.2019.135/2990
and MMP-13 gene expression in osteoarthritis synoviocytes after Mesenchymal Stem Cell Wharton Jelly (r = 0.662). Introduction.
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45
Expression of collagenases (matrix metalloproteinase-1, 8, 13 ...
https://synapse.koreamed.org/articles/1097365
In human studies, MMP-1, 2, 3, 9, and 13 have been detected in the synovial fluid of osteoarthritis (OA) patients3456, and expression and ...
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https://synapse.koreamed.org/articles/1097365
In human studies, MMP-1, 2, 3, 9, and 13 have been detected in the synovial fluid of osteoarthritis (OA) patients3456, and expression and ...
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46
Serum and knee synovial fluid matrix metalloproteinase-13 ...
https://www.aott.org.tr/Content/files/sayilar/386/386-3739.pdf
loproteinase-13 (MMP-13) and tumor necrosis factor-alpha (TNF-α) in 2 stages of osteoarthritis, and investigate their correlation with ...
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https://www.aott.org.tr/Content/files/sayilar/386/386-3739.pdf
loproteinase-13 (MMP-13) and tumor necrosis factor-alpha (TNF-α) in 2 stages of osteoarthritis, and investigate their correlation with ...
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47
The induction of matrix metalloproteinase and cytokine ...
https://www.pnas.org/doi/10.1073/pnas.0409781102
Rheumatoid arthritis is a chronic inflammatory disease characterized by ... induced the synthesis of MMP-1, MMP-3, MMP-9, and MMP-13 in fibroblasts.
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https://www.pnas.org/doi/10.1073/pnas.0409781102
Rheumatoid arthritis is a chronic inflammatory disease characterized by ... induced the synthesis of MMP-1, MMP-3, MMP-9, and MMP-13 in fibroblasts.
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48
Overexpression of MMP13 in human osteoarthritic ... - CORE
https://core.ac.uk/download/pdf/33560480.pdf
Introduction: In vitro and animal model of osteoarthritis (OA) studies suggest that ... expression levels of TGFB1, BMP2, SMAD3 and MMP13 in human cartilage ...
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https://core.ac.uk/download/pdf/33560480.pdf
Introduction: In vitro and animal model of osteoarthritis (OA) studies suggest that ... expression levels of TGFB1, BMP2, SMAD3 and MMP13 in human cartilage ...
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49
Metformin attenuates cartilage degeneration in an ... - Aging-US
https://www.aging-us.com/article/102635/text
There were lower OARSI scores and fewer MMP-13-positive cells in DMM mice and ... Articular cartilage degeneration was graded using the Osteoarthritis ...
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https://www.aging-us.com/article/102635/text
There were lower OARSI scores and fewer MMP-13-positive cells in DMM mice and ... Articular cartilage degeneration was graded using the Osteoarthritis ...
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50
Joint Diseases and Matrix Metalloproteinases: A Role for MMP ...
https://zero.sci-hub.se/4178/86cbd1e970706b22accc52146734486d/takaishi2008.pdf
the MMP proteases in arthritis. MMP-13 is expressed by chondrocytes and synovial cells in human OA and RA and is thought to play a critical role in ...
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https://zero.sci-hub.se/4178/86cbd1e970706b22accc52146734486d/takaishi2008.pdf
the MMP proteases in arthritis. MMP-13 is expressed by chondrocytes and synovial cells in human OA and RA and is thought to play a critical role in ...
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51
Research Snapshot: Biomedical engineers demonstrate ...
https://news.vanderbilt.edu/2021/09/01/research-snapshot-biomedical-engineers-demonstrate-potential-for-the-first-clinically-successful-osteoarthritis-drug/
Post-traumatic osteoarthritis—caused by degraded cartilage that cushions the ... The protein coding gene MMP13 is responsible for degrading ...
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https://news.vanderbilt.edu/2021/09/01/research-snapshot-biomedical-engineers-demonstrate-potential-for-the-first-clinically-successful-osteoarthritis-drug/
Post-traumatic osteoarthritis—caused by degraded cartilage that cushions the ... The protein coding gene MMP13 is responsible for degrading ...
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52
Human Gene MMP13 (ENST00000260302.8) from ...
http://genome.ucsc.edu/cgi-bin/hgGene?hgg_gene=uc001phl.2&org=human
Description: Homo sapiens matrix metallopeptidase 13 (MMP13), mRNA. ... as well as in disease processes, such as arthritis and metastasis.
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http://genome.ucsc.edu/cgi-bin/hgGene?hgg_gene=uc001phl.2&org=human
Description: Homo sapiens matrix metallopeptidase 13 (MMP13), mRNA. ... as well as in disease processes, such as arthritis and metastasis.
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53
Association Risk of Metalomatrix Proteinase Enzymes Levels ...
https://annalsofrscb.ro/index.php/journal/article/view/3915
... (MMP-1,MMP-9 And MMP-13) with Development of Rheumatoid Arthritis ... Matrix metalloproteinase are family of metalloendopeptidases ...
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https://annalsofrscb.ro/index.php/journal/article/view/3915
... (MMP-1,MMP-9 And MMP-13) with Development of Rheumatoid Arthritis ... Matrix metalloproteinase are family of metalloendopeptidases ...
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54
Tolerogenic nanoparticles induce type II collagen–specific ...
https://www.science.org/doi/10.1126/sciadv.abo5284
Osteoarthritis (OA) is a common joint disease that involves cartilage ... to the increased MMP13 expression and decreased Col II expression.
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https://www.science.org/doi/10.1126/sciadv.abo5284
Osteoarthritis (OA) is a common joint disease that involves cartilage ... to the increased MMP13 expression and decreased Col II expression.
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55
Increased activity and expression of matrix metalloproteinase ...
https://journals.physiology.org/doi/10.1152/ajpheart.00036.2002
In some inflammatory reactions such as rheumatoid arthritis (10) and ... by a previous study (13) as manifested by reduced deposition of types I and III ...
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https://journals.physiology.org/doi/10.1152/ajpheart.00036.2002
In some inflammatory reactions such as rheumatoid arthritis (10) and ... by a previous study (13) as manifested by reduced deposition of types I and III ...
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56
A Strategic Approach to Knee Arthritis Treatment: From ...
https://books.google.com/books?id=fwtIEAAAQBAJ&pg=PA82&lpg=PA82&dq=mmp+13+arthritis&source=bl&ots=-rcUqpUjnR&sig=ACfU3U23O_L1Zy-c0mUzQfu-R48oWu2_Lg&hl=en&sa=X&ved=2ahUKEwjr7ZXi_tn7AhUmUaQEHSIVDzwQ6AF6BQibAhAD
Among MMPs, MMP-13 plays an important role in the process of degeneration in osteoarthritis. MMP-13 expression is more restricted to connective tissues.
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https://books.google.com/books?id=fwtIEAAAQBAJ&pg=PA82&lpg=PA82&dq=mmp+13+arthritis&source=bl&ots=-rcUqpUjnR&sig=ACfU3U23O_L1Zy-c0mUzQfu-R48oWu2_Lg&hl=en&sa=X&ved=2ahUKEwjr7ZXi_tn7AhUmUaQEHSIVDzwQ6AF6BQibAhAD
Among MMPs, MMP-13 plays an important role in the process of degeneration in osteoarthritis. MMP-13 expression is more restricted to connective tissues.
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57
Targeting a Single Pathway to Treat Peripheral Neuropathy
https://www.medscape.com/viewarticle/864984
Dr Alan Jacobs reviews the results of a recent study finding that overactivation of matrix-metalloproteinase-13 is a key mechanism ...
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https://www.medscape.com/viewarticle/864984
Dr Alan Jacobs reviews the results of a recent study finding that overactivation of matrix-metalloproteinase-13 is a key mechanism ...
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58
Functional foods in improving bone health during aging - DOI
https://doi.org/10.1016/b978-0-323-90581-7.00009-8
These changes range from minor stiffness to severe arthritis (Goltzman, 2019). ... It was found that sesamin inhibited the expression of MMP-1, -3, and -13 ...
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https://doi.org/10.1016/b978-0-323-90581-7.00009-8
These changes range from minor stiffness to severe arthritis (Goltzman, 2019). ... It was found that sesamin inhibited the expression of MMP-1, -3, and -13 ...
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59
文章详细信息 - 生命的化学
http://www.life.ac.cn/WKD/WebPublication/paperDigest.aspx?paperID=e23ecf07-7a6d-4ee3-aaea-501e0daff4b9
Follistatin-like protein 1 induction of matrix metalloproteinase 1, 3 and 13 gene expression in rheumatoid arthritis synoviocytes requires MAPK, ...
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http://www.life.ac.cn/WKD/WebPublication/paperDigest.aspx?paperID=e23ecf07-7a6d-4ee3-aaea-501e0daff4b9
Follistatin-like protein 1 induction of matrix metalloproteinase 1, 3 and 13 gene expression in rheumatoid arthritis synoviocytes requires MAPK, ...
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60
Alterations in Circulating Immune Cells in Neovascular Age ...
https://typeset.io/pdf/alterations-in-circulating-immune-cells-in-neovascular-age-30ehon2de5.pdf
13 (13). 0.7342. Body Mass Index (mean ± SD). 26.4 (4.9) ... inflammatory diseases such as arthritis34 and atherosclerosis35. ere is now.
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https://typeset.io/pdf/alterations-in-circulating-immune-cells-in-neovascular-age-30ehon2de5.pdf
13 (13). 0.7342. Body Mass Index (mean ± SD). 26.4 (4.9) ... inflammatory diseases such as arthritis34 and atherosclerosis35. ere is now.
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61
Agua de limón: ¿cuáles son los verdaderos beneficios?
https://www.medicalnewstoday.com/articles/es/agua-con-limon
Translate this page
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https://www.medicalnewstoday.com/articles/es/agua-con-limon
Translate this page
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62
Arthritis: New Insights for the Healthcare Professional: ...
https://books.google.com/books?id=nCsalh_I79cC&pg=PA217&lpg=PA217&dq=mmp+13+arthritis&source=bl&ots=91MWDXXfxB&sig=ACfU3U19qSHg131UdC5ftWn8bjOmn7XupA&hl=en&sa=X&ved=2ahUKEwjr7ZXi_tn7AhUmUaQEHSIVDzwQ6AF6BQiYAhAD
B ligand (RANKL), IL-6, PGE, and MMP-13, but not the osteoprotegerin and MMP-1 levels. The mRNA levels of RANKL, IL-6, COX-2, and MMP-13 in synovium were ...
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https://books.google.com/books?id=nCsalh_I79cC&pg=PA217&lpg=PA217&dq=mmp+13+arthritis&source=bl&ots=91MWDXXfxB&sig=ACfU3U19qSHg131UdC5ftWn8bjOmn7XupA&hl=en&sa=X&ved=2ahUKEwjr7ZXi_tn7AhUmUaQEHSIVDzwQ6AF6BQiYAhAD
B ligand (RANKL), IL-6, PGE, and MMP-13, but not the osteoprotegerin and MMP-1 levels. The mRNA levels of RANKL, IL-6, COX-2, and MMP-13 in synovium were ...
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63
Bone and Osteoarthritis - Page 60 - Google Books Result
https://books.google.com/books?id=4WB46tmPhRUC&pg=PA60&lpg=PA60&dq=mmp+13+arthritis&source=bl&ots=QC_7K-YpS2&sig=ACfU3U31TuxrqQJtwnuwXEjbOag1E1fhuQ&hl=en&sa=X&ved=2ahUKEwjr7ZXi_tn7AhUmUaQEHSIVDzwQ6AF6BQiZAhAD
... DeGennaro LJ (2001) Postnatal expression in hyaline cartilage of constitutively active human collagenase-3 (MMP-13) induces osteoarthritis in mice.
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https://books.google.com/books?id=4WB46tmPhRUC&pg=PA60&lpg=PA60&dq=mmp+13+arthritis&source=bl&ots=QC_7K-YpS2&sig=ACfU3U31TuxrqQJtwnuwXEjbOag1E1fhuQ&hl=en&sa=X&ved=2ahUKEwjr7ZXi_tn7AhUmUaQEHSIVDzwQ6AF6BQiZAhAD
... DeGennaro LJ (2001) Postnatal expression in hyaline cartilage of constitutively active human collagenase-3 (MMP-13) induces osteoarthritis in mice.
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64
Oxford Textbook of Osteoarthritis and Crystal Arthropathy
https://books.google.com/books?id=KeIoDQAAQBAJ&pg=PA43&lpg=PA43&dq=mmp+13+arthritis&source=bl&ots=ka0gfbzGjG&sig=ACfU3U2-yu5zYzFbJgLaJjzPCiw4sLsSig&hl=en&sa=X&ved=2ahUKEwjr7ZXi_tn7AhUmUaQEHSIVDzwQ6AF6BQiTAhAD
Enochson L, Stenberg J, Brittberg M, Lindahl A. GDF5 reduces MMP13 expression in human chondrocytes via DKK1 mediated canonical Wnt signaling inhibition.
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https://books.google.com/books?id=KeIoDQAAQBAJ&pg=PA43&lpg=PA43&dq=mmp+13+arthritis&source=bl&ots=ka0gfbzGjG&sig=ACfU3U2-yu5zYzFbJgLaJjzPCiw4sLsSig&hl=en&sa=X&ved=2ahUKEwjr7ZXi_tn7AhUmUaQEHSIVDzwQ6AF6BQiTAhAD
Enochson L, Stenberg J, Brittberg M, Lindahl A. GDF5 reduces MMP13 expression in human chondrocytes via DKK1 mediated canonical Wnt signaling inhibition.
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65
Rheumatoid Arthritis: Etiology, Consequences and Co-Morbidities
https://books.google.com/books?id=cCyaDwAAQBAJ&pg=PA121&lpg=PA121&dq=mmp+13+arthritis&source=bl&ots=kTb65X3yuj&sig=ACfU3U0mFXnWF2kPuonsrAzMn_h0wptFrQ&hl=en&sa=X&ved=2ahUKEwjr7ZXi_tn7AhUmUaQEHSIVDzwQ6AF6BQiSAhAD
... MMP 13: 5'-tcctacaaatctcgcgggaat-3' (fwd), gcatttctcggagcctctca-3' (rev), ... synovial tissues from patients with rheumatoid arthritis We studied the ...
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https://books.google.com/books?id=cCyaDwAAQBAJ&pg=PA121&lpg=PA121&dq=mmp+13+arthritis&source=bl&ots=kTb65X3yuj&sig=ACfU3U0mFXnWF2kPuonsrAzMn_h0wptFrQ&hl=en&sa=X&ved=2ahUKEwjr7ZXi_tn7AhUmUaQEHSIVDzwQ6AF6BQiSAhAD
... MMP 13: 5'-tcctacaaatctcgcgggaat-3' (fwd), gcatttctcggagcctctca-3' (rev), ... synovial tissues from patients with rheumatoid arthritis We studied the ...
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66
Brain Autophagy: Healing the Toxic Brain - DrJockers.com
https://drjockers.com/brain-autophagy/
13. Sitting is bad for your brain — not just your metabolism or heart: Thinning ... Kaczmarek L, Sandi C. Role for MMP-9 in stress-induced downregulation of ...
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https://drjockers.com/brain-autophagy/
13. Sitting is bad for your brain — not just your metabolism or heart: Thinning ... Kaczmarek L, Sandi C. Role for MMP-9 in stress-induced downregulation of ...
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67
US court ban on NZ fish exports receives mixed reaction
https://www.indianweekender.co.nz/Pages/ArticleDetails/7/21040/new-zealand/us-court-ban-on-nz-fish-exports-receives-mixed-reaction
Election 2020: Our MMP voting system explained ... Here are some facts and myths about arthritis that you should be aware of.
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https://www.indianweekender.co.nz/Pages/ArticleDetails/7/21040/new-zealand/us-court-ban-on-nz-fish-exports-receives-mixed-reaction
Election 2020: Our MMP voting system explained ... Here are some facts and myths about arthritis that you should be aware of.
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68
Firestein & Kelley’s Textbook of Rheumatology - E-Book
https://books.google.com/books?id=LGbvDwAAQBAJ&pg=PA59-IA4&lpg=PA59-IA4&dq=mmp+13+arthritis&source=bl&ots=Kyx8emmuNo&sig=ACfU3U2vqtHJ9A84QV45QerIa_g1RjeP-A&hl=en&sa=X&ved=2ahUKEwjr7ZXi_tn7AhUmUaQEHSIVDzwQ6AF6BQiRAhAD
C/EBPbeta and RUNX2 cooperate to degrade cartilage with MMP-13 as the ... Pathophysiology of osteoarthritis: canonical NF-kappaB/IKKbeta-dependent and ...
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https://books.google.com/books?id=LGbvDwAAQBAJ&pg=PA59-IA4&lpg=PA59-IA4&dq=mmp+13+arthritis&source=bl&ots=Kyx8emmuNo&sig=ACfU3U2vqtHJ9A84QV45QerIa_g1RjeP-A&hl=en&sa=X&ved=2ahUKEwjr7ZXi_tn7AhUmUaQEHSIVDzwQ6AF6BQiRAhAD
C/EBPbeta and RUNX2 cooperate to degrade cartilage with MMP-13 as the ... Pathophysiology of osteoarthritis: canonical NF-kappaB/IKKbeta-dependent and ...
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69
Osteoarthritis E-Book: A Companion to Rheumatology
https://books.google.com/books?id=6Fl1fCosrt4C&pg=PA27&lpg=PA27&dq=mmp+13+arthritis&source=bl&ots=EljdLaaZsh&sig=ACfU3U00orERfUlKn0BYw3Hq4Hiqyn0kIg&hl=en&sa=X&ved=2ahUKEwjr7ZXi_tn7AhUmUaQEHSIVDzwQ6AF6BQiQAhAD
... its action at reducing the local release in the bone of active TGF-β, and inhibition of the expression levels of MMP-9 in bone and MMP-13 in cartilage.
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https://books.google.com/books?id=6Fl1fCosrt4C&pg=PA27&lpg=PA27&dq=mmp+13+arthritis&source=bl&ots=EljdLaaZsh&sig=ACfU3U00orERfUlKn0BYw3Hq4Hiqyn0kIg&hl=en&sa=X&ved=2ahUKEwjr7ZXi_tn7AhUmUaQEHSIVDzwQ6AF6BQiQAhAD
... its action at reducing the local release in the bone of active TGF-β, and inhibition of the expression levels of MMP-9 in bone and MMP-13 in cartilage.
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70
Frontiers in Medicinal Chemistry , Volume (1)
https://books.google.com/books?id=XYYkA73cnCoC&pg=PA57&lpg=PA57&dq=mmp+13+arthritis&source=bl&ots=cLJoI2g6m7&sig=ACfU3U0-VLw-cE1D15pln3l1-Hq-3r2fyg&hl=en&sa=X&ved=2ahUKEwjr7ZXi_tn7AhUmUaQEHSIVDzwQ6AF6BQiaAhAD
In the case of 43 (IC50 of 50 nM for MMP13) and 44 (IC50 = 15 nM for MMP-3) ... in diseases such as rheumatoid arthritis, multiple sclerosis, and psoriasis.
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https://books.google.com/books?id=XYYkA73cnCoC&pg=PA57&lpg=PA57&dq=mmp+13+arthritis&source=bl&ots=cLJoI2g6m7&sig=ACfU3U0-VLw-cE1D15pln3l1-Hq-3r2fyg&hl=en&sa=X&ved=2ahUKEwjr7ZXi_tn7AhUmUaQEHSIVDzwQ6AF6BQiaAhAD
In the case of 43 (IC50 of 50 nM for MMP13) and 44 (IC50 = 15 nM for MMP-3) ... in diseases such as rheumatoid arthritis, multiple sclerosis, and psoriasis.
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71
herxing cancer - Abilissimome.it
https://abilissimome.it/herxing-cancer.html
Mar 13, 2022 · Herxing- the side effects of parasites It's All Good Mar 13 Yes we ... of matrix metalloproteinases (MMPs) facilitates tumor cell invasion.
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https://abilissimome.it/herxing-cancer.html
Mar 13, 2022 · Herxing- the side effects of parasites It's All Good Mar 13 Yes we ... of matrix metalloproteinases (MMPs) facilitates tumor cell invasion.
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72
Biology 2013 Grade 12 Past Paper - Autogermana
https://preciocerradobmw.autogermana.com.co/viewcontent?ID=97980&FileName=Biology%202013%20Grade%2012%20Past%20Paper.pdf
Biology Class 12 CBSE Board 13 Years Skill-wise & Chapter-wise Solved Papers (2008 - 20) ... Strains of the Caprine Arthritis Encephalitis Virus Disease (S.
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https://preciocerradobmw.autogermana.com.co/viewcontent?ID=97980&FileName=Biology%202013%20Grade%2012%20Past%20Paper.pdf
Biology Class 12 CBSE Board 13 Years Skill-wise & Chapter-wise Solved Papers (2008 - 20) ... Strains of the Caprine Arthritis Encephalitis Virus Disease (S.
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73
Clearbridge Investments LLC Has $1.09 Million Holdings in ...
https://reporter.am/2022/11/27/clearbridge-investments-llc-has-1-09-million-holdings-in-option-care-health-inc-nasdaqopch.html
... target on shares of Amgen in a report on Tuesday, September 13th. ... plaque psoriasis, rheumatoid arthritis, and psoriatic arthritis; ...
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https://reporter.am/2022/11/27/clearbridge-investments-llc-has-1-09-million-holdings-in-option-care-health-inc-nasdaqopch.html
... target on shares of Amgen in a report on Tuesday, September 13th. ... plaque psoriasis, rheumatoid arthritis, and psoriatic arthritis; ...
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