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1
https://www.ahajournals.org/doi/10.1161/01.HYP.0000168924.37091.58
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2
https://www.nature.com/articles/s41371-020-00477-1
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3
https://www.nejm.org/doi/full/10.1056/NEJMoa2111437
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4
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8444354/
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5
https://clinicaltrials.gov/ct2/show/NCT01206062
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6
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9
https://jasn.asnjournals.org/content/17/4_suppl_2/S36
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10
https://journals.lww.com/co-nephrolhypertens/fulltext/2000/05000/large_multicentre_hypertension_trials.13.aspx
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11
https://jamanetwork.com/journals/jama/fullarticle/2697010
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https://academic.oup.com/aje/article/153/1/72/107808
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14
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15
https://www.tandfonline.com/doi/full/10.3109/08037051.2014.946787
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18
https://www.openaccessjournals.com/articles/impact-of-recent-landmark-clinical-trials-on-hypertension-treatment.pdf
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19
https://www.mayo.edu/research/clinical-trials/diseases-conditions/high-blood-pressure-(hypertension)
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20
https://clinmedjournals.org/articles/jhm/journal-of-hypertension-and-management-jhm-2-019.php?jid=jhm
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21
https://onlinelibrary.wiley.com/doi/10.1111/j.1524-6175.2003.02676.x
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22
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23
https://www.sprinttrial.org/public/Protocol_Current.pdf
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24
https://www.mja.com.au/journal/2005/182/2/hypertension-guidelines-meta-analyses-and-clinical-trials-do-we-assume-too-much
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25
https://research.tilburguniversity.edu/en/publications/dementia-and-disability-outcomes-in-large-hypertension-trials-les
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26
https://www.centerwatch.com/clinical-trials/listings/condition/85/high-blood-pressure-hypertension/
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27
https://www.uptodate.com/contents/choice-of-drug-therapy-in-primary-essential-hypertension
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28
https://www.rxfiles.ca/rxfiles/uploads/documents/HTNLandmarkHypertensionTrials.pdf
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29
https://clinicaltrials.ucsf.edu/high-blood-pressure
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30
https://www.medscape.com/viewarticle/971486
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31
https://www.ema.europa.eu/en/documents/scientific-guideline/guideline-clinical-investigation-medicinal-products-treatment-hypertension-revision-4_en.pdf
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32
https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-020-04493-x
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33
https://www.acc.org/Latest-in-Cardiology/Clinical-Trials/2022/04/01/03/19/CHAP
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34
http://www.bplttc.org/
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35
http://deepblue.lib.umich.edu/bitstream/handle/2027.42/73430/j.1524-6175.2003.02676.x.pdf?sequence=1
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36
https://www.utsouthwestern.edu/newsroom/articles/year-2018/hypertension-algorithm.html
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37
https://ichgcp.net/clinical-trials-registry/NCT04559074
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38
https://www.medscape.org/viewarticle/457696_7
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39
https://clinicaltrials.ucbraid.org/high-blood-pressure
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40
https://www.globenewswire.com/en/news-release/2021/07/01/2256368/0/en/George-Medicines-initiates-two-Phase-III-trials-of-triple-combination-candidate-to-treat-hypertension.html
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41
https://www.pcdsociety.org/resources/details/studies-that-changed-clinical-practice-evidence-for-the-management-of-hypertension-in-diabetes-the-key-studies
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42
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0117560
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43
https://www.revespcardiol.org/en-after-allhat-trial-what-do-articulo-13049667
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44
https://www.karger.com/Article/Fulltext/489855
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45
https://utswmed.org/medblog/hypertension-systolic-trial/
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46
https://www.aafp.org/news/health-of-the-public/20191106bedtimehbpmeds.html
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47
https://clinicaltrials.ucsd.edu/trial/NCT02299414
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48
https://meridian.allenpress.com/aph/article/8/1/24/432086/Evaluating-Recent-Therapeutic-Trials-in-Pulmonary
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49
https://www.atsjournals.org/doi/full/10.1513/pats.200803-032SK
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https://brandonbiocatalyst.com/2022/09/08/george-medicines-provides-single-pill-triple-combination-candidate-for-hypertension-to-veronica-nigeria-trial/
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https://www.unitedhealthgroup.com/newsroom/posts/2020-05-18-yale-study-hypertension-medication.html
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54
https://formative.jmir.org/2022/3/e33057
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55
https://www.jhltonline.org/article/S1053-2498(22)01856-3/fulltext
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56
https://www.fiercepharma.com/drug-delivery/alnylam-takes-biannual-hypertension-prospect-into-phase-2-trial
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57
https://www.researchgate.net/publication/349337518_Home_blood_pressure_monitors_owned_by_participants_in_a_large_decentralised_clinical_trial_in_hypertension_the_Treatment_In_Morning_versus_Evening_TIME_study
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58
https://www.dbmi.columbia.edu/lancet-legend-hypertension-study/
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59
http://www.newswise.com/articles/key-learnings-from-recent-hypertension-clinical-trials-what-do-we-know-now?section=latest&previous_id=552071
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60
https://europe.medtronic.com/xd-en/healthcare-professionals/therapies-procedures/cardiovascular/renal-denervation/clinical-data/randomized-controlled-trials.html
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61
https://www.yahoo.com/now/cincor-pharma-announces-topline-data-123000488.html
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62
https://investors.biogen.com/news-releases/news-release-details/lecanemab-confirmatory-phase-3-clarity-ad-study-met-primary
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63
https://www.cancer.gov/publications/dictionaries/cancer-terms/def/cohort
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64
https://www.biopharmadive.com/news/cincor-hypertension-blood-pressure-drug-trial-results/637406/
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65
https://en.wikipedia.org/wiki/Clinical_trial
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66
https://www.eisai.com/news/2022/news202271.html
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67
https://www.biospace.com/article/releases/cincor-pharma-announces-topline-data-for-phase-2-halo-trial-evaluating-selective-aldosterone-synthase-inhibitor-baxdrostat-in-uncontrolled-hypertension/
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https://www.fiercebiotech.com/biotech/cincors-hypertension-drug-loses-its-halo-after-phase-2-fail-plunging-stock-44
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69
https://hscweb3.hsc.usf.edu/blog/2015/10/02/nih-hypertension-study-makes-a-stronger-case-for-aiming-for-even-lower-blood-pressure/
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70
https://www.rwjbh.org/blog/2019/june/finding-a-new-treatment-for-high-blood-pressure/
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71
https://www.youtube.com/watch?v=zsHIvtbBxzM
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72
https://www.fda.gov/patients/drug-development-process/step-3-clinical-research
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73
https://www.merck.com/
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74
https://www.mayoclinic.org/diseases-conditions/high-blood-pressure/diagnosis-treatment/drc-20373417
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75
https://www.withpower.com/clinical-trials/hypertension
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76
https://www.cnn.com/2022/10/28/health/blood-pressure-dementia-wellness
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77
https://www.novartis.com/
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78
https://www.abbvie.com/
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79
https://www.marketscreener.com/quote/stock/CINCOR-PHARMA-INC-131369220/news/CinCor-Pharma-Announces-Topline-Data-for-Phase-2-HALO-Trial-Evaluating-Selective-Aldosterone-Synthas-42418915/
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80
https://news.cision.com/cereno-scientific/r/cereno-scientific-participates-at-the-19th-global-cvct-forum-2022-discussing-clinical-trials-in-card,c3675999
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81
https://scrip.pharmaintelligence.informa.com/SC147440/CinCor-Plans-Baxdrostat-Phase-III-Despite-Phase-II-Miss-In-Uncontrolled-Hypertension
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82
https://www.ama-assn.org/delivering-care/hypertension/when-targeting-high-bp-draw-evidence-based-framework
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83
https://www.heart.org/en/news/2020/12/07/few-clinical-studies-examine-high-blood-pressure-treatments-for-black-americans
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84
https://www.medpagetoday.com/podcasts/ap-cardiology/82821
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85
https://healthmatch.io/high-blood-pressure/what-causes-high-diastolic-blood-pressure
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https://stockhouse.com/news/press-releases/2022/11/28/cincor-pharma-announces-topline-data-for-phase-2-halo-trial-evaluating-selective
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https://www.medicalnewstoday.com/articles/322284
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https://www.goodrx.com/paxlovid/known-side-effects
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https://www.gurufocus.com/news/1899995/cincor-pharma-announces-topline-data-for-phase-2-halo-trial-evaluating-selective-aldosterone-synthase-inhibitor-baxdrostat-in-uncontrolled-hypertension
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90
https://sphweb.bumc.bu.edu/otlt/mph-modules/bs/bs704_confidence_intervals/bs704_confidence_intervals_print.html
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91
https://www.eurekalert.org/news-releases/972813
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92
https://www.prnewswire.com/news-releases/eisai-presents-full-results-of-lecanemab-phase-3-confirmatory-clarity-ad-study-for-early-alzheimers-disease-at-clinical-trials-on-alzheimers-disease-ctad-conference-301689627.html
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93
https://news.harvard.edu/gazette/story/2022/11/dash-diet-offers-even-more-benefits-for-black-adults-and-women/
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94
https://smallcaps.com.au/invex-therapeutics-recruiting-iih-patients-nz-clinical-trial-regulatory-approvals/
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https://jdc.jefferson.edu/phlspoptalk/29/
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