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1 Causes of Restless Legs Syndrome (RLS)
https://www.hopkinsmedicine.org/neurology_neurosurgery/centers_clinics/restless-legs-syndrome/what-is-rls/causes.html
Cerebrospinal fluid obtained by lumbar puncture has shown that the iron storage protein ferritin is low in RLS patients, despite these patients having normal ...
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2 Restless Legs Syndrome: Detection and Management ... - AAFP
https://www.aafp.org/pubs/afp/issues/2000/0701/p108.html
Recent studies have shown that decreased iron stores (indicated by serum ferritin levels below 50 ng per mL [50 μg per L] can exacerbate RLS ...
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3 Hepcidin and ferritin levels in restless legs syndrome - Nature
https://www.nature.com/articles/s41598-020-68851-0
Although iron deficiency has been associated with RLS pathogenesis, low serum ferritin has only been reported in 10–20% of adults with RLS.
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4 Serum Iron Studies (Addition of Restless Leg Syndrome as a ...
https://www.cms.gov/medicare-coverage-database/view/ncacal-decision-memo.aspx?proposed=N&ncaid=178
RLS severity and blood tests were repeated after 2 months of iron supplementation. All patients had higher ferritin levels (median increase 34 μg/l) and median ...
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5 Correlates of Nonanemic Iron Deficiency in Restless Legs ...
https://www.frontiersin.org/articles/10.3389/fneur.2020.00298/full
Recent studies suggest RLS patients should be considered iron deficient when their ferritin concentration is below 75 μg/L (10, 11, 27). However ...
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6 Worsening Restless Leg Syndrome Symptoms as a ...
https://journals.sagepub.com/doi/full/10.1177/23337214211067875
Current clinical practice guidelines include the recommendation to check serum ferritin levels and provide iron supplementation if the ferritin ...
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7 Medical Case Report on Repeat Treatment of Restless Legs ...
https://www.karger.com/Article/FullText/518911
Indeed the strongest environmental factor that relates to RLS is iron deficiency (<50 μg/L plasma ferritin; [12]). Several studies have shown an inverse ...
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8 A Clinical Primer on Restless Legs Syndrome: What We Know ...
https://www.ajmc.com/view/a09_12aug_rls_sethi
An autopsy study found that H-ferritin was markedly reduced while L-ferritin was present but had a different morphology.9 In addition, another ...
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9 Restless legs syndrome and low brain iron levels in patients ...
https://jnnp.bmj.com/content/76/7/1009
An alteration in the blood–brain barrier iron transport mechanism may be implicated in the pathophysiology of RLS symptoms. Further studies, analysing CSF ...
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10 Restless Legs Syndrome Workup - Medscape Reference
https://emedicine.medscape.com/article/1188327-workup
All patients with symptoms of restless legs syndrome (RLS) should be tested for iron deficiency. At a minimum, a ferritin level should be ...
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11 Clinical Characteristics and Efficacy of Iron Treatment for ...
https://www.sleepmedres.org/journal/view.php?number=124
Ferritin is a key factor in iron homeostasis and may be related to the clinical manifestations of RLS. Ferritin levels have a modest inverse ...
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12 The Management of Restless Legs Syndrome: An Updated ...
https://www.mayoclinicproceedings.org/article/S0025-6196(20)31489-0/fulltext
the base requirement for any use of intravenous iron therapy in RLS is that the serum ferritin concentration should be less than 100 μg/L (and ...
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13 Evidence-based and consensus clinical practice guidelines ...
https://www.sciencedirect.com/science/article/pii/S1389945717315599
Ferric carboxymaltose (1000 mg) is effective for treating moderate to severe RLS in those with serum ferritin <300 μg/l and could be used as first-line ...
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14 Management of restless legs syndrome and periodic limb ...
https://www.uptodate.com/contents/management-of-restless-legs-syndrome-and-periodic-limb-movement-disorder-in-adults
Oral iron – Supportive evidence for oral iron includes results of a 12-week randomized trial in which 18 adults with RLS and a serum ferritin ≤ ...
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15 Restless Leg Syndrome, or Willis-Ekbom Disease, Causes
https://www.verywellhealth.com/restless-leg-syndrome-and-iron-deficiency-3014755
One condition that is strongly linked to symptoms of RLS is iron deficiency. The relationship between iron deficiency and RLS symptoms has been ...
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16 Restless Legs Syndrome: Pathophysiology and the Role of ...
https://chiro.org/Graphics_Box_ALT-MED/FULL/Restless_Legs_Syndrome.pdf
Serum ferritin levels in those with RLS were consistently below. 50 ng/mL (Figure 2) and indicate increased risk for an iron metabolism-related etiology for RLS.
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17 Restless Legs Syndrome: How to Fight a Condition That's ...
https://www.muhealth.org/our-stories/restless-legs-syndrome-how-fight-condition-thats-stealing-your-sleep
One of the most common causes of restless leg syndrome is low iron in the brain. This can be estimated, to a fair degree, through ferritin level testing in ...
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18 Controversies and Challenges in Defining the Etiology and ...
https://www.amjmed.com/article/S0002-9343(06)01294-0/abstract
Earley C.J.; et al. An update on the dopaminergic treatment of restless legs syndrome and periodic limb movement disorder. ... Serum iron declines by up to 50% at ...
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19 Iron for the treatment of restless legs syndrome - Trotti, LM
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD007834.pub3/full
Restless legs syndrome (RLS) is a common neurologic disorder that is associated with peripheral iron deficiency in a subgroup of patients.
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20 If RLS Is Presumed, Order a Serum Ferritin Level
https://www.patientcareonline.com/view/if-rls-presumed-order-serum-ferritin-level
Serum ferritin values less than 50 µg/L can exacerbate RLS symptoms and predict positive response to iron supplementation, typically ferrous ...
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21 Iron Biology: What We Should Know When Managing ...
https://www.rls.org/file/member-publications/webinars/2018/01.25.18-Iron-Earley.pdf
First to report the benefits of IV iron treatment on RLS symptoms in those ... increased RLS severity and decreased sleep efficiency. Lower iron stores are ...
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22 Restless Legs Syndrome in Chronic Kidney Disease
https://jcsm.aasm.org/doi/abs/10.5664/jcsm.8028
Median ferritin levels in patients with RLS tended to be higher than in those without RLS (51.2 versus 40.1 ng/mL; P = .08). Inflammation (elevated CRP) also ...
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23 A review of the interface between restless legs syndrome and ...
http://sleepscience.org.br/details/208/en-US/sleep-disorders--a-review-of-the-interface-between-restless-legs-syndrome-and-iron-metabolism
The pathophysiology of RLS remains unclear, although roles for dopamine dysfunction and brain iron deficiency have been proposed [28]. A low ferritin level (< ...
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24 Mitochondrial Ferritin in the Substantia Nigra in Restless Legs ...
https://academic.oup.com/jnen/article/68/11/1193/2916982
Restless legs syndrome (RLS) is a neurological disorder that is thought to involve decreased iron availability in the brain. Iron is required ...
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25 Abnormalities in CSF concentrations of ferritin and transferrin ...
https://n.neurology.org/content/54/8/1698
Restless legs syndrome (RLS) has been associated commonly with iron deficiency.1,2 However, iron supplementation even in RLS patients without ...
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26 How credible are the proposed theories of Restless leg ...
https://www.entvoicesnoring.com/articles/2019/11/15/how-credible-are-the-proposed-theories-of-restless-leg-syndrome-pathophysiology-discuss-and-critically-evaluate-the-evidence
Lower serum ferritin levels correlate with greater restless leg syndrome symptom severity but are also often normal in restless leg syndrome ...
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27 Restless Leg Syndrome Is Underdiagnosed in Hereditary ...
https://www.mdpi.com/2077-0383/10/9/1993
The most common conditions associated with RLS include iron deficiency with low serum ferritin levels, and subsequent low central nervous system ...
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28 Restless legs syndrome in patients with high serum ferritin ...
https://www.researchgate.net/publication/51675068_Restless_legs_syndrome_in_patients_with_high_serum_ferritin_and_normal_iron_levels
The abnormal iron deposits in basal ganglia and substantia nigra revealed a complex disorder of iron metabolism in the C.N.S. RLS in patients ...
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29 Severe Restless Legs Syndrome in ... - California Sleep Society
https://californiasleepsociety.org/news/severe-restless-legs-syndrome/
One of the most common conditions associated with RLS is iron deficiency, with multiple studies demonstrating a correlation between low ...
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30 Are you missing this simple treatment for restless legs?
https://www.health.harvard.edu/diseases-and-conditions/are-you-missing-this-simple-treatment-for-restless-legs
Treating RLS with food. "Dietary iron may sometimes be enough to treat RLS if your ferritin level is at or below 50 micrograms per liter (mcg/L).
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31 What Causes Restless Legs Syndrome (RLS)? - WebMD
https://www.webmd.com/brain/restless-legs-syndrome/rls-causes
Many different medical conditions have been linked to RLS. The two most common conditions are iron-deficiency anemia (low blood count) and peripheral neuropathy ...
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32 Restless legs syndrome - Causes - NHS
https://www.nhs.uk/conditions/restless-legs-syndrome/causes/
Underlying health condition · have iron deficiency anaemia (low levels of iron in the blood can lead to a fall in dopamine, triggering restless legs syndrome) ...
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33 Restless legs syndrome and related disorders - Mount Sinai
https://www.mountsinai.org/health-library/report/restless-legs-syndrome-and-related-disorders
As many as 25% of people with chronic kidney disease have RLS. The exact cause of this is not known but may be related to co-existing anemia and iron deficiency ...
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34 Iron for Restless Legs Syndrome - Natural Medicines
https://naturalmedicines.therapeuticresearch.com/news/news-items/2017/july/iron-for-restless-legs-syndrome.aspx
The AAN now recommends iron 325 mg along with vitamin C 100 mg twice daily for RLS patients with low blood ferritin levels (<75 mcg/L). Iron can also be given ...
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35 Exploring the Relationship Between Parkinson Disease and ...
https://jamanetwork.com/journals/jamaneurology/fullarticle/781607
RESTLESS LEGS syndrome (RLS) is a common neurological syndrome that is usually either genetic or secondary to other medical conditions, including low iron ...
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36 Association of hypo ferritinemia and restless legs syndrome in ...
https://www.bbrc.in/bbrc/2016july-sepPDF/BBRC8_031.pdf
554 HYPO FERRITINEMIA AND RESTLESS LEGS SYNDROME WITH IRON DEFICIENCY ANEMIA ... Severe restless legs syndrome causes the high- est levels of sleep ...
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37 Restless legs syndrome: An overview of pathophysiology ...
https://www.spandidos-publications.com/10.3892/etm.2021.11108
Nevertheless, most RLS patients have normal serum ferritin and no indication of peripheral iron deficiency. Rather, a hallmark of RLS appears to ...
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38 Repeated IV doses of iron provides effective supplemental ...
https://worldsleepsociety.org/wp-content/uploads/2018/06/PIIS1389945705000559.pdf
high ferritin levels was not in themselves a guarantee of sustained ... Keywords: Restless legs syndrome; Iron; Ferritin; Treatment; Ferrlecit; Intravenous.
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39 Iron Dysregulation in Restless Legs Syndrome - Clinical Gate
https://clinicalgate.com/iron-dysregulation-in-restless-legs-syndrome/
In tissues from patients with RLS, iron and H-ferritin were decreased, transferrin was increased, and L-ferritin was the same as for control ...
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40 A double-blind, placebo-controlled trial of intravenous iron ...
https://www.ajkd.org/article/S0272-6386(04)00009-5/abstract
Multiple blood donations associated with iron deficiency in patients with restless legs syndrome. ... Iron stores, measured by plasma iron and ferritin levels, ...
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41 Is iron therapy effective in treating restless leg syndrome?
https://journals.lww.com/ebp/Fulltext/2021/11000/Is_iron_therapy_effective_in_treating_restless_leg.15.aspx
Intravenous ferric carboxymaltose is recommended as a first-line treatment of moderate-to-severe RLS in patients with serum ferritin <300 μg/L and transferrin < ...
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42 Iron for the treatment of restless legs syndrome - Cochrane
https://www.cochrane.org/CD007834/MOVEMENT_iron-treatment-restless-legs-syndrome
Low blood iron levels may be part of the cause of restless legs syndrome. Iron can be taken as a pill or given as an injection into the ...
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43 Human L-ferritin deficiency is characterized by idiopathic ...
https://rupress.org/jem/article/210/9/1779/45721/Human-L-ferritin-deficiency-is-characterized-by
Besides, brain iron deficiency is related to neurodegenerative processes like restless leg syndrome (RLS; Salas et al., 2010) and epilepsy (Ozaydin et al., ...
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44 Iron Supplements to Treat Restless Leg Syndrome
https://restlesslegssyndrome.sleep-disorders.net/iron-supplements
Iron supplementation can help people with restless legs syndrome increase iron levels in the brain. This helps the parts of the brain that ...
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45 A Genetic Risk Factor for Periodic Limb Movements in Sleep
https://www.nejm.org/doi/full/10.1056/NEJMoa072743
RLS has a negative impact on quality of life and chronic medical conditions. ... Iron deficiency and iron excess have been associated with the ...
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46 Restless Legs Syndrome Presenting as an Acute ... - Hindawi
https://www.hindawi.com/journals/msi/2011/872948/
Restless legs syndrome is known to be related to low brain iron levels. Multiple sclerosis has been associated with the abnormal accumulation of iron in the ...
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47 Study of Iron Metabolism and Restless Legs Syndrome in ...
https://www.jscimedcentral.com/SleepMedicine/sleepmedicine-3-1045.pdf
a high incidence of iron deficiency without anemia. Thus, has ... iron overload syndrome (DIOS), hyperferritinemia and RLS.
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48 A Case Series of Children with ADHD and Restless Sleep
https://www.heraldopenaccess.us/openaccess/a-case-series-of-children-with-adhd-and-restless-sleep
Even in the small sample size for this pilot study, ferritin levels were ... ADHD has a particularly high comorbidity of Restless Leg Syndrome (RLS) [4], ...
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49 Restless legs syndrome and periodic leg movements
https://www.cambridge.org/core/books/common-pitfalls-in-sleep-medicine/restless-legs-syndrome-and-periodic-leg-movements/05519CA900B129C4886762FBCCA7C094
Restless legs symptoms can be associated with low-normal iron stores. Iron is a cofactor for tyrosine hydroxylase, an enzyme that catalyzes a rate-limiting step ...
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50 Restless Legs Syndrome
https://rarediseases.org/rare-diseases/restless-legs-syndrome/
In primary RLS, the disorder is often genetic in origin or occurs for unknown reasons (idiopathic). Secondary RLS may occur in association with certain ...
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51 Ferritin Level Blood Test: Purpose, Procedure, and Results
https://www.healthline.com/health/ferritin
Both high and low iron levels may indicate a serious underlying problem. ... liver disease, such as chronic hepatitis C; restless leg syndrome. Ferritin is ...
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52 Peripheral Iron Metabolism is Associated with Leg Movements ...
https://www.dovepress.com/peripheral-iron-metabolism-is-associated-with-leg-movements-on-polysom-peer-reviewed-fulltext-article-NSS
Peripheral Iron Metabolism is Associated with Leg Movements on Polysomnography but Not with the Severity of Restless Legs Syndrome or Its ...
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53 Restless leg syndrome and iron - YouTube
https://www.youtube.com/watch?v=_Z3uP8C1ZKI
MedCram - Medical Lectures Explained CLEARLY
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54 Clinical Characteristics and Efficacy of Iron ... - Semantic Scholar
https://pdfs.semanticscholar.org/bf86/9259becc3369d43c4837185ecf02a5a778be.pdf
Restless legs syndrome (RLS) is associated with dopaminergic dysfunction, and iron deficiency, manifesting as low ferritin. However, ferritin levels do not ...
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55 Adult ferritin treatment threshold too high for kids with restless ...
https://www.mdedge.com/pediatrics/article/82787/pediatrics/adult-ferritin-treatment-threshold-too-high-kids-restless-sleep
In both adults and children, iron deficiency has been linked to the presence and severity of restless legs syndrome (RLS) and periodic limb ...
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56 Ferritin Blood Test: MedlinePlus Medical Test
https://medlineplus.gov/lab-tests/ferritin-blood-test/
Higher than normal ferritin levels can mean you have too much iron in your body. Conditions that cause increased iron levels include: Liver ...
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57 A review of the interface between restless legs syndrome and ...
https://cdn.publisher.gn1.link/sleepscience.org.br/pdf/v7n4a09.pdf
Metabolism OR Iron Deficiency AND Restless Legs Syndrome,” 145 articles were screened, ... Ferritin is increased in a number of conditions unrelated to iron.
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58 Severe Restless Legs Syndrome in the Setting ... - Proceedings
https://proceedings.med.ucla.edu/wp-content/uploads/2020/08/Kashani-A200630SK-BLM-formatted.pdf
Restless Legs Syndrome (RLS), also known as Willis-Ekbom ... conditions associated with RLS is iron deficiency, with multiple.
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59 Willis-Ekbom Disease, A Conundrum in Hemochromatosis
https://sciforschenonline.org/journals/sleep-disorders-medical-care/article-data/JSDMC-1-102/JSDMC-1-102.pdf
Restless Leg Syndrome (RLS)/Willis-Ekbom Disease (WED) ... high ferritin levels, patients in the cohort with more severe RLS.
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60 Iron for the treatment of restless legs syndrome (Review)
https://areasaludbadajoz.com/docencia_investigacion/lecturas_recomendadas/Trotti_et_al-2019-Cochrane_Database_of_Systematic_Reviews.pdf
Genome-wide association stud- ies have found single nucleotide polymorphisms in six different genes that confer increased risk for RLS, periodic limb move-.
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61 Mayo Clinic Finds Restless Legs Syndrome In Children ...
https://www.sciencedaily.com/releases/2005/01/050104113419.htm
One commonality in the restless legs syndrome patients was a low iron level in the blood (as measured by serum ferritin) seen in 83 percent of ...
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62 Restless Legs Syndrome - Treatment Recommendations
https://www.hdrxservices.com/restless-legs-syndrome-treatment-recommendations/
– Follow up ferritin levels initially after 3-4 months, and then every 3-6 months until the serum ferritin level is >100 µg/L. If there is not ...
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63 The night time hustle: managing restless legs syndrome in ...
https://bpac.org.nz/bpj/2012/december/restlesslegs.aspx
A serum ferritin test should be considered for patients with restless legs syndrome without an obvious secondary cause, as iron deficiency is a common ...
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64 Restless Legs Syndrome and Iron 1
https://hrcak.srce.hr/file/344770
KEYWORDS: restless legs syndrome, Willis-Ekbom disease, iron ... levels. However, when serum ferritin levels are normal or high or when oral ...
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65 Restless Leg Syndrome | Children's Hospital Colorado
https://www.childrenscolorado.org/conditions-and-advice/conditions-and-symptoms/conditions/restless-leg-syndrome/
Studies have found associations between low stores of iron in the body and increased RLS symptoms, probably because of iron's important role in brain dopamine ...
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66 New-onset restless leg syndrome in a COVID-19 patient
https://www.panafrican-med-journal.com/content/article/38/318/full
CSF ferritin levels are found to be lower in patients with RLS symptoms, however, in the serum, these proteins might not be good predictors of ...
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67 Iron status and restless legs syndrome in the elderly - Gale
https://go.gale.com/ps/i.do?id=GALE%7CA15465834&sid=googleScholar&v=2.1&it=r&linkaccess=abs&issn=00020729&p=AONE&sw=w
The RLS patients showed reduced serum ferritin levels when compared to the control subjects. Vitamin B12, serum iron, folate and hemoglobin levels were similar ...
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68 [Restless legs syndrome in patients with high serum ferritin ...
http://www.medicinacomplementar.com.br/biblioteca/pdfs/Doencas/do-1464.pdf
high serum ferritin and normal iron levels]. ... To document the association between restless legs syndrome (RLS) and high ferritin levels in five patients.
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69 Intravenous Iron Metabolism in Restless Legs Syndrome
https://clinicaltrials.gov/ct2/show/NCT00685815
To determine the effects of high-dose infusions of iron on Restless Legs Syndrome (RLS) symptoms and brain concentrations of iron.
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70 Ferritin Test: What It Is, Purpose, Procedure & Results
https://my.clevelandclinic.org/health/diagnostics/17820-ferritin-test
What does a high ferritin level mean? ... Ferritin test results may be high due to hemochromatosis (iron overload), a condition in which your body ...
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71 Does Repeated Dosing of Intravenous Ferric Carboxymaltose ...
https://mdpi-res.com/d_attachment/jcm/jcm-11-01673/article_deploy/jcm-11-01673-v2.pdf?version=1647837198
Brain iron deficiency plays a key role in the pathophysiology of restless legs syndrome. (RLS) [1–3]. In recent years, an increased number ...
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72 KEGG DISEASE: Restless legs syndrome
https://www.genome.jp/entry/H01597
A high prevalence of iron deficiency has been found among patients with RLS. It has been reported that treatment with oral iron supplements resulted in ...
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73 Restless legs syndrome - Diagnosis and treatment - Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/restless-legs-syndrome/diagnosis-treatment/drc-20377174
Sometimes, treating an underlying condition, such as iron deficiency, greatly relieves symptoms of RLS . Correcting an iron deficiency may ...
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74 Hepcidin and ferritin levels in restless legs syndrome
https://www.hal.inserm.fr/inserm-02938904/document
Augmentation is a treatment-induced paradoxical worsening of RLS symptoms caused by long-term high dose dopaminergic therapy, and remains the.
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75 Restless Legs Syndrome in X-linked adrenoleukodystrophy
https://aldconnect.org/wp-content/uploads/2022/05/Restless-Leg-Syndrome-in-X-Linked-Adrenoleukodystrophy.pdf
This pilot study suggests a high prevalence of RLS in adults with ALD, ... It is more common in conditions with iron deficiency [6],.
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76 Restless Leg Syndrome: A Neglected Diagnosis - Brieflands
https://brieflands.com/articles/num-17169.html
Restless legs syndrome (RLS) is an irresistible urge to move legs that ... and a high ferritin level in patients with ESRD is not a reliable ...
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77 Prevalence of Restless Legs Syndrome (RLS) in children with ...
https://ijp.mums.ac.ir/article_16867.html
The prevalence of RLS in this sample of beta thalassemia patients was zero. Quality of life scores were low, but iron and ferritin levels were in the normal ...
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78 Restless leg syndrome in children with celiac disease
https://www.turkishjournalpediatrics.org/pdf.php?&id=1806
with serum ferritin, folic acid or 25 (OH) vitamin D levels in Celiac disease group. In this study we did not determine an increased prevalence of RLS.
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79 Iron and restless legs syndrome: treatment, genetics and ...
https://europepmc.org/article/med/28057495
Adding iron to the ventral midbrain (VMB) by an indwelling cannula produce an increased extra-cellular dopamine in the striatum [18]. It has now been well ...
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80 Linking restless legs syndrome with Parkinson's disease
https://translationalneurodegeneration.biomedcentral.com/articles/10.1186/2047-9158-1-6
Among the strongest arguments against a common pathophysiology is the role of iron in RLS and PD. While elevated iron levels in the substantia ...
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81 Restless Legs Syndrome: Current Concepts about Disease ...
https://tremorjournal.org/article/10.5334/tohm.322/
Pathologically, the most consistent finding is striatal iron deficiency in RLS patients. A host of other biological systems are also altered in ...
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82 Restless Legs Syndrome - American Thoracic Society
https://www.thoracic.org/patients/patient-resources/resources/rls.pdf
Some medical conditions may trigger or be associated with RLS. These include iron deficiency, kidney failure,. Parkinson's disease, diabetes, rheumatoid ...
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83 Remedies for Restless Legs Syndrome - Dr Wholeness
https://drwholeness.com/blog/remedies-for-restless-leg-syndrome/
But many people are iron deficient but have high hepcidin. The reason being is that they have high inflammation and poor liver detoxification.
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84 Restless legs syndrome - Illnesses & conditions - NHS inform
https://www.nhsinform.scot/illnesses-and-conditions/brain-nerves-and-spinal-cord/restless-legs-syndrome
If restless legs syndrome is caused by iron deficiency anaemia, iron supplements may be all that's needed to treat the symptoms. Read more about treating ...
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85 Full article: Restless legs syndrome: differential diagnosis and ...
https://www.tandfonline.com/doi/full/10.2147/cia.s4143
The treatment of RLS firstly demands a thorough clinical evaluation to rule out causes of secondary RLS, the most common of which is iron ...
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86 Restless Legs Syndrome & Periodic Limb Movements During ...
https://www.utmedicalcenter.org/medical-care/medical-services/procedures-treatments/restless-legs-syndrome-periodic-limb-movements-during-sleep/
Blood ferritin levels are often lower in RLS patients (typically below 50 mcg/L), and iron deficiency seems to be most pronounced when measured in the brain or ...
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87 Restless leg syndrome and migraine: Is there a common ...
https://www.neurology-asia.org/articles/neuroasia-2021-26(4)-743.pdf
Keywords: Restless leg syndrome, migraine, iron deficiency, inflammation. Neurology Asia 2021; 26(4) : 743 – 749. Address correspondence to: Gulhan Saricam, ...
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88 Relationship between restless leg syndrome and quality of life ...
https://jag.journalagent.com/agri/pdfs/AGRI_27_2_73_78.pdf
disease, anemia, low serum ferritin levels and high serum levels of parathyroid hormone have been lin- ked to RLS. A number of studies suggest that iron.
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89 Neurochemistry of Idiopathic Restless Legs Syndrome
https://touchneurology.com/movement-disorders/journal-articles/neurochemistry-of-idiopathic-restless-legs-syndrome/
Although the exact pathophysiology of idiopathic RLS (iRLS) is not well established, dopaminergic dysfunction and brain iron insufficiency are ...
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90 Anyone suffer from haemochromatosis o... - Restless Legs Syn...
https://healthunlocked.com/rlsuk/posts/141750395/anyone-suffer-from-haemochromatosis-or-have-high-ferritin-levels
Now it's gone over. While investigating reasons for that, I discovered people who suffer from RLS often have high ferritin levels, which led me ...
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91 Restless Legs Syndrome - Cancer Care of Western New York
https://www.cancercarewny.com/content.aspx?chunkiid=21806
A number of studies have linked RLS to low levels of iron in the blood. ... In one analysis of the medical records of 27 people with RLS, those with the most ...
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92 Restless legs syndrome in patients on chronic hemodialysis
https://www.elsevier.es/es-revista-dialisis-trasplante-275-articulo-restless-legs-syndrome-in-patients-S1886284513000763
RLS was reported in 14 of 50 hemodialysis patients (28%). Low hemoglobin, low serum ferritin levels and increased consumption of coffee in hemodialysis patients ...
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93 Restless legs syndrome is a public health problem
https://tidsskriftet.no/en/2021/11/editorial/restless-legs-syndrome-public-health-problem
In Norway, the combination oxycodone + naloxone is approved for treatment of RLS. Iron supplement is recommended when ferritin levels fall below ...
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94 Restless legs syndrome and related disorders
https://www.limamemorial.org/health-library/In-Depth%20Reports/10/000095
Neuropathy due to other medical problems like diabetes is also associated with increased risk of RLS. Abnormalities of Iron Metabolism. Iron ...
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95 Dialysis Patients With Restless Leg Syndrome - Cureus
https://www.cureus.com/articles/39208-dialysis-patients-with-restless-leg-syndrome-can-we-relieve-their-suffering
The suggested mechanisms for RLS pathophysiology considered that imbalance of iron and dopamine in the CNS can be the leading cause of RLS. They ...
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96 Treating Severe Refractory and Augmented Restless Legs ...
https://journal.chestnet.org/article/S0012-3692(22)01008-X/fulltext
Addressing factors that worsen RLS (eg, iron deficiency, ... movement disorder (dyskinesias), in RLS they can produce increased severity of ...
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