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1 Restless Legs Syndrome, Insomnia And Brain Chemistry
https://www.hopkinsmedicine.org/news/media/releases/restless_legs_syndrome_insomnia_and_brain_chemistry_a_tangled_mystery_solved
Marked improvement in RLS symptoms seen with drugs that stimulate the dopamine system and RLS-like symptoms produced with drug that block the dopamine system ...
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2 Possible Sites of Therapeutic Action in Restless Legs ...
https://www.karger.com/Article/Fulltext/328431
Dopaminergic drugs have shown efficacy as an RLS treatment in numerous large-scale clinical studies [17], and dopamine agonists improve RLS ...
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3 Restless legs syndrome - Causes - NHS
https://www.nhs.uk/conditions/restless-legs-syndrome/causes/
There's evidence to suggest restless legs syndrome is related to a problem with part of the brain called the basal ganglia. The basal ganglia uses a chemical ( ...
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4 Restless Legs Syndrome
https://rarediseases.org/rare-diseases/restless-legs-syndrome/
The exact underlying cause of RLS symptoms is unknown. However, many researchers suggest that abnormalities in a certain neurotransmitter (dopamine) in the ...
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5 Restless legs syndrome - Neurology
https://n.neurology.org/content/neurology/67/1/125.full.pdf
49. Commissiong JW, Sedgwick EM. Letter: Dopamine and noradrenaline in human spinal cord. Lancet 1975;1:347. 50. Carp ...
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6 Restless Legs Syndrome: Clinical Implications for Psychiatrists
https://www.psychiatrictimes.com/view/restless-legs-syndrome-clinical-implications-psychiatrists
It is important to note that RLS has not been found to be a treatment-emergent adverse effect of non-serotonergic antidepressants, such as the ...
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7 Restless Legs Syndrome - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/medicine-and-dentistry/restless-legs-syndrome
The strongest evidence for a dopaminergic pathology in RLS comes from the pharmacological response to medications. To date, all evaluated agents that enhance ...
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8 Neurochemistry of Idiopathic Restless Legs Syndrome
https://touchneurology.com/movement-disorders/journal-articles/neurochemistry-of-idiopathic-restless-legs-syndrome/
The excellent therapeutic response of RLS to dopaminergic drugs, together with some neuropathological, neuroimaging, biochemical and ...
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9 Pivotal Role of Adenosine Neurotransmission in Restless ...
https://www.frontiersin.org/articles/10.3389/fnins.2017.00722/full
The symptomatology of Restless Legs Syndrome (RLS) includes periodic leg movements during sleep (PLMS), dysesthesias, and hyperarousal.
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10 Restless legs syndrome - Illnesses & conditions - NHS inform
https://www.nhsinform.scot/illnesses-and-conditions/brain-nerves-and-spinal-cord/restless-legs-syndrome
If nerve cells become damaged, the amount of dopamine in the brain is reduced, which causes muscle spasms and involuntary movements. Dopamine levels naturally ...
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11 Glutamate, Hyperarousal and Restless Legs Syndrome
https://clinicaltrials.gov/ct2/show/NCT01675323
Restless Legs Syndrome (RLS) research has focused on the sensory features and failed to address an important aspect of RLS; ...
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12 Venlafaxine-Induced Restless Legs Syndrome
https://dusunenadamdergisi.org/storage/upload/pdfs/1586251999-en.pdf
Key words: Antidepressants, restless legs syndrome, venlafaxine, serotonin-norepinephrine reuptake inhibitors. ÖZET. Venlafaksinin neden olduğu huzursuz ...
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13 Selective Serotonin Reuptake Inhibitor/Serotonin-Norepinephr...
https://journals.lww.com/practicalpsychiatry/Fulltext/2016/07000/Selective_Serotonin_Reuptake.2.aspx
Because restless legs syndrome (RLS) is a problematic syndrome, demonstrating an association between use of selective serotonin reuptake inhibitors (SSRIs)/ ...
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14 How credible are the proposed theories of Restless leg ...
https://www.entvoicesnoring.com/articles/2019/11/15/how-credible-are-the-proposed-theories-of-restless-leg-syndrome-pathophysiology-discuss-and-critically-evaluate-the-evidence
Although a baseline hyperdopaminergic state exists, there is a circadian pattern to dopaminergic activity in restless leg syndrome, with a ...
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15 Management of restless legs syndrome and periodic limb ...
https://www.uptodate.com/contents/management-of-restless-legs-syndrome-and-periodic-limb-movement-disorder-in-adults
Dopamine agonists — The non-ergot dopamine agonists, pramipexole, ropinirole, and rotigotine, are effective in the treatment of RLS at low doses ...
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16 Restless Legs Syndrome Induced by Escitalopram
https://accpjournals.onlinelibrary.wiley.com/doi/pdfdirect/10.1592/phco.28.2.271
Certain antidepressant drugs, including the selective serotonin reuptake inhibitors (SSRIs) and serotonin- norepinephrine reuptake inhibitors (SNRIs), may ...
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17 The Brain's Dopamine Systems and Their ... - Clinical Gate
https://clinicalgate.com/the-brains-dopamine-systems-and-their-relevance-to-restless-legs-syndrome/
... Dopamine Systems and Their Relevance to Restless Legs Syndrome ... The family of catecholamines includes norepinephrine, epinephrine, ...
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18 Abstract - pi :: Psychiatry Investigation
https://www.psychiatryinvestigation.org/m/journal/view.php?number=495
Bupropion is a selective norepinephrine and dopamine reuptake inhibitor with ... Restless legs syndrome (RLS), which is characterized by an ...
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19 Long-term Treatment of Restless Legs Syndrome With ...
https://jamanetwork.com/journals/jamaneurology/fullarticle/786586
Conclusions Dopamine agonists continued to effectively treat RLS without long-term adverse events but often required adjustments across time. The higher rate of ...
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20 RLS (Restless Legs Syndrome) Causes and Medical Conditions
https://www.webmd.com/brain/restless-legs-syndrome/rls-causes
Dopaminergic agents: These drugs, including Sinemet -- a combination of levodopa and carbidopa -- increase the level of dopamine in the brain and may improve ...
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21 Selective Serotonin Reuptake Inhibitor ... - ResearchGate
https://www.researchgate.net/publication/305382734_Selective_Serotonin_Reuptake_InhibitorSerotonin-Norepinephrine_Reuptake_Inhibitor_Use_as_a_Predictor_of_a_Diagnosis_of_Restless_Legs_Syndrome
Request PDF | Selective Serotonin Reuptake Inhibitor/Serotonin-Norepinephrine Reuptake Inhibitor Use as a Predictor of a Diagnosis of Restless Legs Syndrome ...
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22 Restless legs syndrome - Diagnosis and treatment - Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/restless-legs-syndrome/diagnosis-treatment/drc-20377174
Sometimes dopamine medications that have worked for a while to relieve your RLS become ineffective, or you notice your symptoms returning ...
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23 The Adenosine Hypothesis of Restless Legs Syndrome
https://www.liebertpub.com/doi/10.1089/caff.2019.0001
Restless Legs Syndrome (RLS) is a very prevalent neurological disorder. According to the RLS epidemiology, symptoms, and treatment study, ...
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24 Restless legs syndrome: An overview of pathophysiology ...
https://www.spandidos-publications.com/10.3892/etm.2021.11108
A direct consequence of the activation of hypoxic pathways would be the increase of dopaminergic activity, which is indubitable in RLS patients.
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25 Remedies for Restless Legs Syndrome - Dr Wholeness
https://drwholeness.com/blog/remedies-for-restless-leg-syndrome/
In an otherwise healthy person, dopamine levels naturally have a downward trajectory towards the end of the day. This would be why restless leg ...
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26 Pathophysiology of the Restless Legs Syndrome
https://www.e-jsm.org/journal/view.php?number=30
CNS dopaminergic systems are strongly implicated in RLS that are closely linked to CNS iron homeostasis. Evidences showing the efficacy of dopaminergic drugs, ...
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27 Restless legs syndrome
https://aasm.org/resources/factsheets/rls.pdf
Restless legs syndrome (RLS) is a sleep-related movement disorder that involves an almost irresistible urge to move the legs at night. This urge tends to be ...
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28 Expert Q&A: Understanding Restless Leg Syndrome - Healthline
https://www.healthline.com/health/restless-leg-syndrome/expert-qa
Currently it is believed that the cause is a low level of a neurotransmitter called dopamine that uses iron as a building block. Lower levels of dopamine, or ...
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29 Restless legs syndrome in Parkinson disease - Nature
https://www.nature.com/articles/s41598-017-10593-7
PD-RLS frequency was 40.37%. PD-RLS group had longer duration, higher stage and scores of motor symptoms, depression, anxiety, sleep disorders, ...
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30 Altered dopaminergic profile in the putamen and substantia ...
https://academic.oup.com/brain/article/132/9/2403/355510
Restless leg syndrome (RLS) is a sensorimotor disorder. Clinical studies have implicated the dopaminergic system in RLS, while others have ...
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31 Restless Legs Syndrome: clinical features, diagnosis and a ...
https://pn.bmj.com/content/practneurol/17/6/444.full.pdf
Restless leg syndrome (RLS) is a chronic neurological disorder that interferes with rest and sleep, leading to poor quality of life and ...
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32 The Management of Restless Legs Syndrome: An Updated ...
https://www.mayoclinicproceedings.org/article/S0025-6196(20)31489-0/fulltext
Dopamine agonists are an effective treatment option for RLS and were formerly used for first-line treatment of RLS. However, because of ...
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33 Restless Leg Syndrome | Michigan Medicine
https://www.uofmhealth.org/conditions-treatments/brain-neurological-conditions/restless-leg-syndrome
Restless leg syndrome (RLS) is an uncomfortable or unpleasant tickling or twitching in the legs. Symptoms also occasionally occur in the arms or other parts ...
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34 Restless Legs Syndrome and Mood Disorders - Psychiatrist.com
https://www.psychiatrist.com/jcp/bipolar/mood-disorders/mood-disorders-restless-legs-syndrome-willis-ekbom/
59,80 Given the purported involvement of dopamine deficiency in the etiology of RLS, it is logical to presume that medications that decrease or ...
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35 Restless Legs Syndrome - Baylor College of Medicine
https://www.bcm.edu/healthcare/specialties/neurology/parkinsons-disease-and-movement-disorders/restless-legs-syndrome
A series of other dopamine drugs called agonists (dopamine mimickers) have since been shown to markedly improve RLS symptoms, often more than Sinemet. These ...
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36 Restless Legs Syndrome - AAFP
https://www.aafp.org/pubs/afp/issues/2008/0715/p235.html
Dopamine agonists are effective treatment for moderate to severe RLS and are the preferred agents for most patients with daily RLS symptoms.
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37 An Updated Algorithm - Restless Legs Syndrome Foundation
https://www.rls.org/21Algorithm
Restless legs syndrome (RLS) is a common disorder. The population prevalence is 1.5% to 2.7% in a subgroup of patients having more severe RLS with symptoms ...
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38 Dopamine: What It Is, Function & Symptoms - Cleveland Clinic
https://my.clevelandclinic.org/health/articles/22581-dopamine
Dopamine agonists are used to treat Parkinson's disease, depression, restless legs syndrome, attention deficit hyperactivity disorder, low sex ...
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39 A review of current treatment strategies for restless legs ...
https://www.rcpjournals.org/content/clinmedicine/14/5/520
Restless legs syndrome (RLS), also known as Willis–Ekbom disease (WED), is a common neurological disorder characterised by an uncontrollable urge to move ...
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40 Restless Legs Syndrome: A Disorder of Dopamine ...
https://www.reliasmedia.com/articles/122157-restless-legs-syndrome-a-disorder-of-dopamine-neurotransmission
The present study re-investigates the controversial question of whether there exist dopamine neurotransmission abnormalities in RLS and, in contrast to previous ...
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41 Restless legs syndrome Information | Mount Sinai - New York
https://www.mountsinai.org/health-library/diseases-conditions/restless-legs-syndrome
No one knows exactly what causes RLS. It may be due to a problem with the way brain cells use dopamine. Dopamine is a brain chemical that helps with muscle ...
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42 Restless Leg Syndrome - Symptoms and Causes
https://www.pennmedicine.org/for-patients-and-visitors/patient-information/conditions-treated-a-to-z/restless-leg-syndrome
No one knows exactly what causes RLS. It may be due to a problem with the way brain cells use dopamine. Dopamine is a brain chemical that helps with muscle ...
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43 New Research Identifies Adenosine Role in RLS
http://rlsfoundation.blogspot.com/2018/07/new-research-identifies-adenosine-role.html
Dr. Ferré's research into RLS builds on decades of science by others on the roles of dopamine and glutamate in the brain for those who ...
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44 Restless Legs Syndrome - Medscape Reference
https://emedicine.medscape.com/article/1188327-overview
Restless legs syndrome (RLS) is a neurologic movement disorder of the limbs that is often associated with a sleep complaint.
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45 The night time hustle: managing restless legs syndrome in ...
https://bpac.org.nz/bpj/2012/december/restlesslegs.aspx
Dopaminergic dysfunction and iron deficiency are both thought to have a role in restless legs syndrome. ... The syndrome is also strongly associated with ...
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46 Imbalance between thyroid hormones and the dopaminergic ...
https://www.scielo.br/j/clin/a/T8HQX8qrm4t7RCwc6tB36kP/?lang=en
Dopamine (DA), when diminished, plays an important role in the pathophysiology of Restless Legs Syndrome (RLS) when decreased DA levels are a primary ...
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47 Restless legs syndrome - Pulmonology Advisor
https://www.pulmonologyadvisor.com/home/decision-support-in-medicine/pulmonary-medicine/restless-legs-syndrome/
RLS patients have brain iron deficiency despite a normal systemic iron status, which leads to dopamine dysfunction that produces the RLS ...
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48 Neuroscience for Kids - Restless Legs Syndrome (RLS)
https://faculty.washington.edu/chudler/rls.html
Dopamine deficiency: medications that increase levels of the neurotransmitter dopamine may relieve RLS symptoms. Diagnosis of RLS. There is no blood test or ...
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49 Restless Legs Syndrome - The Neurology Center
https://www.neurologycenter.com/neurological-conditions/restless-legs-syndrome
The precise mechanisms underlying RLS are not completely understood. The disorder is likely associated with multiple factors including reducing iron stores in ...
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50 Restless legs syndrome, insomnia and brain chemistry
https://www.sciencedaily.com/releases/2013/05/130507134600.htm
Neurologists have long believed RLS is related to a dysfunction in the way the brain uses the neurotransmitter dopamine, a chemical used by ...
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51 Restless legs syndrome: MedlinePlus Medical Encyclopedia
https://medlineplus.gov/ency/article/000807.htm
No one knows exactly what causes RLS. It may be due to a problem with the way brain cells use dopamine. Dopamine is a brain chemical that helps ...
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52 Restless Legs Syndrome - Brain Disorders A-Z
https://brainfoundation.org.au/disorders/restless-legs-syndrome/
Restless Legs Syndrome (RLS) is a neurological disorder characterised by unpleasant sensations in the legs and the compelling need to move the legs, ...
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53 2-Minute Neuroscience: Restless Legs Syndrome - YouTube
https://www.youtube.com/watch?v=D6WmNTQTAfc
Neuroscientifically Challenged
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54 Restless legs syndrome - RACGP
https://www.racgp.org.au/getattachment/87576673-c695-48f6-a806-065da7e5fcc7/Restless-legs-syndrome.aspx
Restless legs syndrome (Rls) is a common, distressing movement disorder, yet many sufferers are not diagnosed or managed adequately. Restless legs syndrome ...
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55 Consensus Guidelines on Rodent Models of Restless Legs ...
https://www.semel.ucla.edu/sites/default/files/publications/21_rls_rodent_guidelines_manconi.pdf
International Restless Legs Syndrome Study Group (IRLSSG). 1Institute of Neurogenomics, Helmholtz ... depressants that modulate serotonin and norepinephrine.
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56 Restless Legs Syndrome across the Lifespan - MDPI
https://www.mdpi.com/1660-4601/17/10/3658/htm
The dopamine pathophysiology of RLS finds its fundamentals in the discovery of the dramatic response to dopaminergic agents (first levodopa, in the early 1980s, ...
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57 Restless legs syndrome - Australian Prescriber
https://www.nps.org.au/australian-prescriber/articles/restless-legs-syndrome-1
Restless legs syndrome is a common but under-recognised disorder. For patients with mild symptoms, no drug treatment may be necessary. For patients with severe ...
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58 New Insights into the Neurobiology of Restless Legs Syndrome
https://journals.sagepub.com/doi/10.1177/1073858418791763
Restless legs syndrome (RLS) is a common sensorimotor disorder, whose basic components include a sensory experience, akathisia, and a sleep-related motor ...
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59 Restless legs syndrome (Chapter 9) - Medication-Induced ...
https://www.cambridge.org/core/books/medicationinduced-movement-disorders/restless-legs-syndrome/CD46F7CA33E9D574AA0263D62355DC11
The issue of whether antidepressants can increase the risk of developing RLS is clinically relevant since many RLS patients suffer from depression, and vice ...
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60 Understanding and Relieving Restless Legs Syndrome
https://www.uspharmacist.com/article/understanding-and-relieving-restless-legs-syndrome
Restless legs syndrome (RLS), also known as nocturnal myoclonus, is a neurologic disorder. ... It is referred to as a movement disorder since ...
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61 The Brain's Dopamine Systems and Their Relevance to ...
https://www.taylorfrancis.com/chapters/edit/10.3109/9781420019575-5/brain-dopamine-systems-relevance-restless-legs-syndrome
Breadcrumbs Section. Click here to navigate to respective pages. Chapter. The Brain's Dopamine Systems and Their Relevance to Restless Legs Syndrome.
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62 Restless Legs Syndrome - Roy Sleep Medicine
https://www.roysleepmedicine.com/restless-legs-syndrome/
There is often a family member with similar symptoms. In adults, the most likely cause of RLS seems to stem from a problem in the brain's dopamine transport ...
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63 Restless legs syndrome: Causes, treatments, and home ...
https://www.medicalnewstoday.com/articles/7882
A person with restless legs syndrome experiences twitchiness and discomfort in the legs, usually after going to bed. As this can lead to insomnia, ...
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64 Restless Leg Syndrome and Parkinson's Disease | APDA
https://www.apdaparkinson.org/article/restless-leg-syndrome/
Restless Legs Syndrome (RLS) is a neurologic and sleep-related condition characterized by an irresistible urge to move the legs. The symptoms respond to ...
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65 Linking restless legs syndrome with Parkinson's disease
https://translationalneurodegeneration.biomedcentral.com/articles/10.1186/2047-9158-1-6
Evidence pointing towards a link includes response to dopaminergic agents in PD and RLS, suggestive of underlying dopamine dysfunction in both ...
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66 Restless legs syndrome: Treatment overview - Allen Press
https://meridian.allenpress.com/mhc/article/2/2/37/36883/Restless-legs-syndrome-Treatment-overview
Restless Legs Syndrome (RLS) is a neurological movement disorder characterized by a distressing urge to move the legs and in some cases, ...
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67 Do I Have Restless Legs Syndrome?
https://www.thensf.org/do-i-have-restless-legs-syndrome/
This part of the brain relies on a chemical called dopamine to signal to the muscles that it's time to act. In normal circumstances, dopamine ...
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68 Comparison of Pregabalin with Pramipexole for Restless Legs ...
https://www.nejm.org/doi/full/10.1056/nejmoa1303646
Background Dopaminergic medications relieve symptoms of the restless legs syndrome (RLS) but have the potential to cause iatrogenic ...
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69 Restless Legs Syndrome | Diagnosis & Treatment - UCHealth
https://www.uchealth.org/diseases-conditions/restless-legs-syndrome/
Dopamine agonist. A dopamine agonist is a drug that mimics the effects of dopamine to relieve restless legs symptoms. Drugs like pramipexole are often the first ...
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70 Restless Leg Syndrome: Essential Facts for Patients
https://www.movementdisorders.org/MDS/Resources/Patient-Education/Restless-Leg-Syndrome.htm
Restless legs syndrome (RLS) is a condition of the nervous system that causes an irresistible urge to move the legs. People with RLS may describe a ...
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71 Venlafaxine-induced restless legs syndrome - BiblioMed.org
https://www.bibliomed.org/?mno=14061
Restless legs syndrome is a movement disorder characterized by complaints of a strong urge to move the legs predominantly during the periods of rest or ...
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72 Restless Legs Syndrome - American Thoracic Society
https://www.thoracic.org/patients/patient-resources/resources/rls.pdf
Restless Legs Syndrome (RLS) is a common sleep-related movement disorder. About 1 in 10 adults in the U.S. have problems from restless leg syndrome. It also can ...
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73 Dipyridamole Appears Effective for Restless Legs Syndrome
https://www.practiceupdate.com/content/dipyridamole-appears-effective-for-restless-legs-syndrome/126771
Restless legs syndrome (RLS) is most often a chronic condition, and better long-term treatments are needed. Preliminary data have shown ...
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74 Restless Legs Syndrome Article - StatPearls
https://www.statpearls.com/ArticleLibrary/viewarticle/28429
Restless leg syndrome, or Willis-Ekbom disease, is a common chronic movement disorder in which patients have an irresistible urge to move their ...
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75 Restless Legs Syndrome as the Initial Presentation of Multiple ...
https://www.hindawi.com/journals/crim/2013/290719/
The restless legs syndrome (RLS) is a common central nervous system disorder. It is characterized by complaints of unpleasant sensation in the legs ...
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76 8 Restless Legs Syndrome Triggers | Everyday Health
https://www.everydayhealth.com/sleep-disorders/restless-leg-syndrome/8-restless-legs-syndrome-triggers/
Although it's not known what causes RLS, research suggests it's related to a dysfunction in the brain's basal ganglia, a group of nerve cells ...
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77 How the brain kickstarts restless legs at night - Futurity
https://www.futurity.org/sleep-restless-legs-syndrome-1858962-2/
Restless legs syndrome begins with excitability and hyperarousal in a part of the brain that controls leg movement, a new study reports.
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78 Restless legs syndrome - Wikipedia
https://en.wikipedia.org/wiki/Restless_legs_syndrome
Restless legs syndrome (RLS), also known as Willis-Ekbom disease (WED), is generally a long-term disorder that causes a strong urge to move one's legs.
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79 Don't Light the Fuse of Restless Legs Syndrome with ...
https://sleepreviewmag.com/sleep-treatments/pharmaceuticals/prescription-drugs/restless-legs-syndrome-dopamine-agonists/
The usual approach is to add an additional RLS treatment to the DA (such as iron, an A2D agent, or an opioid) and then very gradually (over a ...
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80 Restless Leg Syndrome - Life Extension
https://www.lifeextension.com/protocols/neurological/restless-leg-syndrome
Dopamine Agonists. Dopamine agonists are drugs that directly activate dopamine receptors in the nervous system. They are currently considered the first-line ...
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81 Restless Legs | Ohio State Sleep Disorders
https://wexnermedical.osu.edu/sleep-disorders/restless-legs
Restless legs syndrome (RLS) is a neurological disorder characterized by unpleasant sensations in the legs, and an uncontrollable, sometimes overwhelming, ...
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82 Restless Leg Syndrome | Lehigh Valley Health Network
https://www.lvhn.org/conditions/restless-leg-syndrome
Restless legs syndrome (RLS) is a condition in which a person has a strong urge to move his or her legs to stop uncomfortable burning, itching, creeping, ...
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83 Restless Legs Syndrome | McGovern Medical School
https://med.uth.edu/neurosciences/conditions-and-treatments/sleep-disorders/restless-legs-syndrome/
About 10 percent of Americans have experienced RLS symptoms. Researchers believe that an imbalance of dopamine, a chemical in the brain that sends messages to ...
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84 Calming Restless Legs Syndrome | Henry Ford Health
https://www.henryford.com/blog/2019/08/calming-restless-legs-syndrome
“Restless Legs Syndrome is very common due to anemia and the natural aging process of the brain,” he says. “Your brain needs dopamine, ...
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85 The ABCs of RLS: Restless Legs Syndrome - tl;dr pharmacy
https://www.tldrpharmacy.com/content/the-abcs-of-rls-restless-legs-syndrome
If symptoms are reduced by at least 50%, then the patient is determined to have RLS. Due to this responsiveness, the dopaminergic pathway has ...
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86 Dopamine: Role, Related Conditions, and Treatments
https://www.verywellhealth.com/dopamine-5086831
Muscle spasms; Cognitive dysfunction · Restless legs syndrome; Sleep problems; Anxiety; Depression; Mood swings; Swallowing difficulties.
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87 List of 16 Restless Legs Syndrome Medications Compared
https://www.drugs.com/condition/restless-legs-syndrome.html
Restless legs syndrome (RLS) is a nerve disorder characterized by throbbing, pulling, creeping or other unpleasant sensations in the legs and an ...
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88 Signs of restless legs syndrome - Ada Health
https://ada.com/conditions/restless-legs-syndrome/
Restless legs syndrome (RLS), also known as Willis-Ekbom disease, is a chronic condition that causes strong, unpleasant feelings in the legs ...
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89 treatment of opioid withdrawal restless legs syndrome
https://www.chronobiologyinmedicine.org/m/journal/view.php?number=59
Opioids are widely used for treating pain and severe treatment-resistant restless leg syndrome (RLS). However, reports of opioid ...
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90 Restless Legs Syndrome Guide: Causes and Symptoms of RLS
https://www.masterclass.com/articles/restless-leg-syndrome-guide
1. Dopamine imbalance: Research suggests that dopamine imbalance is a potential risk factor for RLS. Dopamine is the brain chemical responsible ...
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91 Restless Legs Syndrome - Child Neurology Foundation
https://www.childneurologyfoundation.org/disorder/restless-legs-syndrome/
Restless legs syndrome (RLS) is characterized by unpleasant sensations in the legs and an irresistible urge to move them. Individuals affected with the ...
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92 Restless Legs Syndrome | FX Medicine
https://www.fxmedicine.com.au/blog-post/restless-legs-syndrome
While theories surrounding the exact aetiology of RLS are still being explored, the pathophysiology behind RLS includes dopaminergic dysfunction ...
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93 Differential Diagnosis and Treatment of Restless Legs ...
https://www.cureus.com/articles/13971-differential-diagnosis-and-treatment-of-restless-legs-syndrome-a-literature-review
Restless legs syndrome (RLS) is a chronic neurological disorder affecting a growing number of people. Patients describe an irresistible urge ...
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94 Augmentation in Restless Legs Syndrome
https://rede.ecu.edu/innovation/available-technologies/augmentation-in-restless-legs-syndrome/
The classical and initially highly effective RLS treatment with dopamine agonists usually fails over time, leading to a worsening of the symptoms with the ...
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