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1 A Meta-analysis of Gene Expression Signatures of ... - PLOS
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1005035
In this study, we performed a meta-analysis of gene expression profiles in relation to BP and hypertension in 7017 individuals from six studies.
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2 Gene Expression Profiling in Hypertension Research
https://www.ahajournals.org/doi/10.1161/01.hyp.0000050927.96979.41
This strategy involves searching for correlations between gene expression patterns and blood pressure and, just like other correlation studies, may reveal ...
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3 Identification of differential gene expression profile from ...
https://bmcmedgenomics.biomedcentral.com/articles/10.1186/s12920-018-0378-2
Essential hypertension is a disease caused by complex, multifactorial and multigenic changes, and it is the result of both gene regulation and ...
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4 Integrative Genomics Analysis Unravels Tissue-Specific ...
https://www.frontiersin.org/articles/10.3389/fcvm.2019.00021/full
Blood pressure (BP) is a highly heritable trait and a major cardiovascular disease risk factor. Genome wide association studies (GWAS) have ...
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5 A Two-Stage Whole-Genome Gene Expression Association ...
https://www.nature.com/articles/s41598-018-19520-w
The substantial heritability (30–60%) of hypertension has prompted scientists to study its genetic underpinnings through genetic and expression ...
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6 Adrenomedullin gene expression differences in mice do not ...
https://www.pnas.org/doi/10.1073/pnas.0611365104
These modest changes in AM gene expression have no effect on basal blood pressure. Although pregnancy and sepsis increase plasma AM levels, genetically reducing ...
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7 A meta-analysis of gene expression signatures of blood ...
https://scholars.duke.edu/display/pub1162820
Genome-wide association studies (GWAS) have uncovered numerous genetic variants (SNPs) that are associated with blood pressure (BP).
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8 regulation of blood pressure Gene Ontology Term (GO:0008217)
http://www.informatics.jax.org/vocab/gene_ontology/GO:0008217
The Gene Ontology (GO) project is a collaborative effort to address the need for ... Synonyms: blood pressure homeostasis | blood pressure regulation ...
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9 A Meta-analysis of Gene Expression ... - Harvard DASH
https://dash.harvard.edu/handle/1/14351321
Genome-wide association studies (GWAS) have uncovered numerous genetic variants (SNPs) that are associated with blood pressure (BP). Genetic variants may lead ...
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10 Identification of Target Genes in Hypertension and Left Vent...
https://journals.lww.com/md-journal/fulltext/2020/07100/identification_of_target_genes_in_hypertension_and.114.aspx
To determine differences in gene expression profiles of hypertension and LV remodeling consequence to hypertension, Gene Expression Omnibus ...
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11 Early left ventricular gene expression profile in response to ...
https://www.tandfonline.com/doi/full/10.1080/08037050601037851
In the present study, we characterized the early changes in gene expression with cDNA expression arrays in response to increase in blood pressure produced ...
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12 Integrative network analysis reveals molecular mechanisms of ...
https://www.embopress.org/doi/10.15252/msb.20145399
Association analysis of blood pressure (BP) and gene expression levels identified individual genes and coexpression network modules that are ...
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13 Large-Scale Multi-Omics Studies Provide New Insights into ...
https://www.mdpi.com/1422-0067/23/14/7557/pdf
Keywords: blood pressure; genome; epigenome; gene expression; functional enrichment. 1. Introduction. High blood pressure (BP), ...
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14 ARTICLE - DNA Methylation Analysis Identifies Loci for Blood ...
https://www.cell.com/ajhg/pdfExtended/S0002-9297(17)30420-2
ciations between methylation, gene expression, and BP. ... Elevated blood pressure (BP) confers a higher risk of heart.
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15 A meta-analysis of gene expression signatures of blood pressure ...
https://leicester.figshare.com/articles/journal_contribution/A_meta-analysis_of_gene_expression_signatures_of_blood_pressure_and_hypertension_/10234205
A meta-analysis of results from six studies of global gene expression profiles of BP and hypertension in whole blood was performed in 7017 individuals who ...
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16 Genes for blood pressure: an opportunity to understand ...
https://academic.oup.com/eurheartj/article/34/13/951/485332
Blood pressure (BP) is also a classical complex genetic trait with heritability estimates of 30–50%. Although much is known about BP regulation, ...
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17 Analysis of genes causing hypertension and stroke in ...
https://www.spandidos-publications.com/10.3892/ijmm.2014.1631
We found that G-1 genes included regulatory genes which control the expression of hypertension-related G-2 genes. We also identified ...
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18 Microarray Analysis of Differential Gene Expression Profile in ...
https://www.medsci.org/v08p0168.htm
The polygenic nature of essential hypertension and its dependence on environmental factors pose a challenge for biomedical research. We hypothesized that the ...
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19 Specific Transcriptome Changes Associated with Blood ...
https://www.liebertpub.com/doi/10.1089/acm.2017.0053
In both BP responders and nonresponders, differentially expressed genes were identified by comparing expression profiles of pre versus post-RR ...
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20 A Meta-analysis of Gene Expression Signatures of Blood ...
https://jhu.pure.elsevier.com/en/publications/a-meta-analysis-of-gene-expression-signatures-of-blood-pressure-a
Genome-wide association studies (GWAS) have uncovered numerous genetic variants (SNPs) that are associated with blood pressure (BP).
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21 Gene expression changes related to bone mineralization ...
https://www.kidney-international.org/article/S0085-2538(21)01030-9/fulltext
In particular, gravity change predominantly impacts blood pressure and bone homeostasis, both of which are controlled mainly by the kidneys.
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22 Gene Expression Meta-analysis Leads to Blood Pressure ...
https://www.genomeweb.com/genetic-research/gene-expression-meta-analysis-leads-blood-pressure-signature
Of those, 27 transcripts typically showed elevated expression with rising blood pressure, while seven transcripts had lower-than-usual ...
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23 Genomics of Blood Pressure and Hypertension
https://www.onlinecjc.ca/article/S0828-282X(20)30217-8/fulltext
The genetic architecture of blood pressure (BP) now includes more than 30 genes, with rare mutations resulting in inherited forms of ...
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24 DNA Methylation Analysis Identifies Loci for Blood Pressure ...
https://www.sciencedirect.com/science/article/pii/S0002929717304202
Additional integrative Mendelian randomization analyses of gene expression and DNA methylation suggested that the expression of TSPAN2 is a ...
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25 Predicting tissue-specific gene expression from whole blood ...
https://www.science.org/doi/10.1126/sciadv.abd6991
Here, we rigorously address this question. We find that an individual's whole blood transcriptome can significantly predict tissue-specific expression levels ...
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26 Harvard Study: Clearing Your Mind Affects Your Genes And ...
https://www.wbur.org/news/2018/04/06/harvard-study-relax-genes
So it doesn't count as absolute proof that meditation lowers blood pressure by altering gene expression. But its authors hope it will be ...
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27 Differential renal gene expression in prehypertensive and ...
https://journals.physiology.org/doi/full/10.1152/ajprenal.00354.2004
Development of hypertension stems from both environmental and genetic factors wherein the kidney plays a central role. Spontaneously hypertensive rats (SHR) ...
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28 Cap analysis of gene expression reveals alternative promoter ...
https://www.life-science-alliance.org/content/5/4/e202101234
We found that the shift in Insr promoter usage was significantly associated with insulin levels and blood pressure within a panel of HXB/BXH ...
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29 Genetics of Blood Pressure Regulation: Possible Paths in the ...
https://www.ajkd.org/article/S0272-6386(19)30729-2/abstract
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. ... Genome-wide association analysis ...
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30 The longevity gene mIndy (I'm Not Dead, Yet) affects blood ...
https://insight.jci.org/articles/view/136083
Pharmacological and biochemical profiling revealed that mIndy affects long-term BP regulation through a potentially novel mechanism regulating ...
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31 Peripheral blood gene expression profiling for cardiovascular ...
https://thehugojournal.springeropen.com/articles/10.1007/s11568-008-9017-x
Moreover, these studies suggest the possibility that gene expression may be developed further as a useful tool to assess average blood pressure ...
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32 Genome-wide Meta-analysis Reveals New Gene Signatures ...
https://pubs.acs.org/doi/10.1021/acsomega.2c02277
We studied the functional role of seven shortlisted DEGs (ADM, EDN1, ANGPTL4, NFIL3, MSR1, CEBPD, and USP8) in hypertension after disease gene ...
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33 Predicting gene expression analysis of PACG implicates ...
https://iovs.arvojournals.org/article.aspx?articleid=2774645
Predicting gene expression analysis of PACG implicates unique inflammatory and blood pressure pathways in across-ancestry disease etiology.
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34 Changes in Gene Expression May Help Explain High Blood ...
https://www.newswise.com/articles/changes-in-gene-expression-may-help-explain-high-blood-pressure-in-pregnancy
According to Walsh, one of the main epigenetic mechanisms is methylation of the DNA, which controls the expression of genes. The increase of ...
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35 Gene Expression Profiling in Pulmonary Hypertension
https://www.atsjournals.org/doi/full/10.1513/pats.200605-128JG
The power of microarray gene expression analysis has been directed at a diverse and complex array of diseases. As will be discussed in this ...
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36 Revelations from Genome-Wide Gene Expression Profiling
https://link.springer.com/article/10.1007/s11906-012-0282-7
Angiotensin II has been implicated in neurogenic hypertension. The first miRNA found to target a mRNA belonging to the renin-angiotensin system ...
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37 Hundreds of new blood pressure gene variations discovered
https://news.vumc.org/2018/12/31/hundreds-of-new-blood-pressure-gene-variations-discovered/
The study, published December 21 by the journal Nature Genetics, also identified specific tissues where blood pressure genes exert their ...
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38 Genetic and Environmental Effects on Gene Expression ...
https://research.rug.nl/en/publications/genetic-and-environmental-effects-on-gene-expression-signatures-of-blood-pressure-a-transcriptomewide-twin-study(fb81ebea-42df-474a-916e-32373c972b1b).html
adult · blood pressure · gene expression · transcriptome · twin study · CARDIOVASCULAR RISK · ASSOCIATION · CARCINOMA ...
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39 Trans-ethnic association study of blood pressure determinants ...
https://discovery.dundee.ac.uk/files/30349091/MVP_BP_Main_Manuscript_08272018.pdf
Our transcriptome-wide association study detected 4,043 blood pressure associations with. 167 genetically-predicted gene expression of 840 genes in 45 ...
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40 Genes, Gene Expression, Environment, and Hypertension | 10
https://www.taylorfrancis.com/chapters/mono/10.1201/9781003129196-10/genes-gene-expression-environment-hypertension-mark-houston-lee-bell
› chapters › mono › gen...
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41 Gene Therapy for Hypertension
https://pgtc.med.ufl.edu/about-us/research/gene-therapy-for-hypertension/
Therefore, we anticipate that gene therapy with an integrative antisense DNA to AT1-R will produce prolonged decreases in blood pressure due to reduced numbers ...
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42 Analyses of differential gene expression in genetic ...
https://www.semanticscholar.org/paper/Analyses-of-differential-gene-expression-in-genetic-Okuda-Sumiya/f8bfcd51318f7b7ede12078d99a1ed0cc2e9f601
The identification of differentially expressed genes may not be an efficient method for selecting candidate genes for hypertension in the ...
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43 Know Your Risk for High Blood Pressure | cdc.gov
https://www.cdc.gov/bloodpressure/risk_factors.htm
Genes likely play some role in high blood pressure, heart disease, and other related conditions. However, it is also likely that people with ...
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44 Relaxation Response Alters Gene Expression to Help Reduce ...
https://www.medindia.net/news/healthinfocus/relaxation-response-alters-gene-expression-to-help-reduce-blood-pressure-178449-1.htm
The changes in gene expression associated with drop in blood pressure are consistent with the physical and inflammatory markers that one ...
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45 Measuring Gene Expression - Learn Genetics Utah
https://learn.genetics.utah.edu/content/precision/expression
Obesity is a major health risk in America that threatens children and adults alike. It can lead to heart disease, high blood pressure, and diabetes, especially ...
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46 Hypertension - Genetics - MedlinePlus
https://medlineplus.gov/genetics/condition/hypertension/
Hypertension is abnormally high blood pressure in the arteries, ... Hypertension is a key feature of some rare genetic disorders, ...
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47 The Interaction of Genetic and Environmental Factors in the ...
https://www.biomed.cas.cz/physiolres/pdf/58%20Suppl%202/58_S33.pdf
adulthood) should involve changes in gene expression involving epigenetic phenomena. ... blood pressure, or the genetic contribution to blood.
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48 Definition of gene expression - NCI Dictionary of Cancer Terms
https://www.cancer.gov/publications/dictionaries/cancer-terms/def/gene-expression
The process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made ...
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49 UI study examines altered gene expression in heart failure
https://medicine.uiowa.edu/content/ui-study-examines-altered-gene-expression-heart-failure
It's a progressive disease that begins when the heart adapts to stressors—high blood pressure, coronary artery disease, or diabetes, ...
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50 A Meta-analysis of Gene Expression Signatures of Blood ...
https://scholarbank.nus.edu.sg/handle/10635/142668
Title: A Meta-analysis of Gene Expression Signatures of Blood Pressure and Hypertension. Authors: Huan T. Esko T. Peters M.J. · Pilling L.C.
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51 Gene Expression Profiles to Categorize Wilms Tumors
https://clinicaltrials.gov/ct2/show/NCT00897637
This laboratory study is using gene expression profiling to identify ... Studying the genes expressed in samples of tumor tissue from patients with cancer ...
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52 How do common variants in the AGT gene cause hypertension?
https://www.gbhealthwatch.com/GND-Hypertension-AGT.php
A genetic variant of the AGT gene leads to increased production of angiotensinogen. People carrying this variant are salt-sensitive, meaning they keep more ...
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53 Chapter:Environmentally Induced Gene Expression
https://www.nap.edu/read/10002/chapter/6
Read chapter Environmentally Induced Gene Expression: New Horizons in Health ... with changes in the expression of genes that regulate blood pressure.
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54 Transcriptional Suppression of CPI-17 Gene Expression in ...
https://journals.asm.org/doi/10.1128/MCB.00070-19
FIG 1 LPS-induced hypotension is associated with selective CPI-17 downregulation in mesenteric arterial smooth muscle cells. (A) Mean arterial pressure (MAP) in ...
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55 Age plays a more important role than genetics in affecting ...
https://www.news-medical.net/news/20221007/Age-plays-a-more-important-role-than-genetics-in-affecting-gene-expression-profiles-as-we-get-older.aspx
In your blood, colon, arteries, esophagus, fat tissue, age plays a much stronger role than your genetics in driving your gene expression ...
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56 Dietary Regulation of Intestinal Gene Expression
https://www.annualreviews.org/doi/abs/10.1146/annurev.nutr.20.1.311
We are becoming increasingly aware of inherited genetic abnormalities as causes of disease. However, alterations in gene expression can also contribute to ...
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57 Increased hyaluronic acid content in idiopathic pulmonary ...
https://erj.ersjournals.com/content/32/6/1504
... pulmonary arterial hypertension lungs, associated with increased hyaluronan synthase 1 and decreased hyaluronoglucosaminidase 1 gene expression.
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58 Familial Hypertension: The Genetics of High Blood Pressure
https://www.healthline.com/health/high-blood-pressure-hypertension/familial-hypertension
Unlike some diseases with only one or a few genes as risk factors, familial hypertension can result from variations in hundreds of different ...
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59 Genes for blood pressure: an opportunity to ... - Read by QxMD
https://read.qxmd.com/read/23303660/genes-for-blood-pressure-an-opportunity-to-understand-hypertension
Blood pressure (BP) is also a classical complex genetic trait with heritability estimates of 30-50%. Although much is known about BP regulation, ...
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60 Control of Gene Expression by Catecholamines and the ...
https://books.google.com/books?id=9f-u4h8gg_IC&pg=PA156&lpg=PA156&dq=blood+pressure+gene+expression&source=bl&ots=NHviRlx-84&sig=ACfU3U1ioiFbXLZhuui221e96L892LPYDQ&hl=en&sa=X&ved=2ahUKEwju_7aXjdP7AhUNjYkEHTaCDsoQ6AF6BAgzEAM
... and chronically , in long - term changes in blood pressure [ 2 ] . ... here we will review the genetic effects of Ang II in responsive tissues ...
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61 Biomedical Index to PHS-supported Research
https://books.google.com/books?id=kK8pmMBaBakC&pg=PA264&lpg=PA264&dq=blood+pressure+gene+expression&source=bl&ots=okMnazf156&sig=ACfU3U362UxDv-_tQwY7gnWeAqvu_AiAKw&hl=en&sa=X&ved=2ahUKEwju_7aXjdP7AhUNjYkEHTaCDsoQ6AF6BAg0EAM
CAR POIHL - 18575-14 0013 Mechanisms in hypertension -- Neural , humoral ... rabbits ) ROÌHL - 35610-05 Renin gene expression in hypertension ( rats , human ) ...
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62 Parkinson's disease - Symptoms and causes - Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/parkinsons-disease/symptoms-causes/syc-20376055
Complications · Blood pressure changes. You may feel dizzy or lightheaded when you stand due to a sudden drop in blood pressure (orthostatic ...
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63 Everything we know about resistance arteries - ReproCELL
https://www.reprocell.com/blog/resistance-arteries
The resistance vasculature is a key regulator of peripheral resistance and blood pressure. Vascular tone is controlled by several mechanisms, ...
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64 FDA Approves HEMGENIX for Hemophilia B - CSL Behring
https://www.cslbehring.com/newsroom/2022/fda-hemgenix
“Today's approval of the world's first gene therapy for hemophilia B is an ... shivering, flushing, rash, and elevated blood pressure.
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65 New target in the fight against heart disease - EurekAlert
https://www.eurekalert.org/news-releases/972557
The endothelial cells that line our blood vessels are in constant ... increased expression of ATIC, a gene essential to purine production.
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66 Management of asymptomatic abdominal aortic aneurysm
https://www.uptodate.com/contents/management-of-asymptomatic-abdominal-aortic-aneurysm
Suggested standards for reporting on arterial aneurysms. ... Flow loading induces macrophage antioxidative gene expression in experimental ...
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67 Novel Phage Therapy Saves Patient with Multidrug-Resistant ...
https://health.ucsd.edu/news/releases/pages/2017-04-25-novel-phage-therapy-saves-patient-with-multidrug-resistant-bacterial-infection.aspx
But the day before scheduled discharge to a long-term acute care ... was soon weaned off of the respirator and blood pressure drugs.
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68 Epigenetics of diabetes Type 2 - Wikipedia
https://en.wikipedia.org/wiki/Epigenetics_of_diabetes_Type_2
In recent years it has become apparent that the environment and underlying mechanisms affect gene expression and the genome outside of the central dogma of ...
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69 Blood pressure highly likely to cause neurotic personality trait
https://www.miragenews.com/blood-pressure-highly-likely-to-cause-neurotic-901131/
Between 30% and 60% of blood pressure is down to genetic factors, and over 1000 genetic single nucleotide polymorphisms, or SNPs for short, are ...
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70 Online Library Mastering Biology Chapter 13 Pdf For Free
https://databalitbang.sultraprov.go.id/cgi-bin/dua?b=L3U4M6&FileName=Mastering-Biology-Chapter-13
... of real time PCR and the mathematics used to measure gene expression More ... blood and plasma, blood clotting, blood platelets, blood pressure testing, ...
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71 Genetics and hypertension: What is the link?
https://www.medicalnewstoday.com/articles/is-hypertension-genetic
Any changes to the genes that contribute to the typical functioning of the lining can lead to a difference in blood vessel structure and impair ...
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72 QUERCETIN - Uses, Side Effects, and More - WebMD
https://www.webmd.com/vitamins/ai/ingredientmono-294/quercetin
Quercetin has antioxidant and anti-inflammatory effects that might help reduce swelling, kill cancer cells, control blood sugar, and help prevent heart ...
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73 CinCor's hypertension drug loses halo after phase 2 fail
https://www.fiercebiotech.com/biotech/cincors-hypertension-drug-loses-its-halo-after-phase-2-fail-plunging-stock-44
Hansa is also partnered with AskBio to test imlifidase as a pre-treatment to the latter's Pompe disease gene therapy. But beyond imlifidase, Hansa's roster is ...
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74 Study reveals effects of carob extract on cardiometabolic ...
https://nutraceuticalbusinessreview.com/news/article_page/Study_reveals_effects_of_carob_extract_on_cardiometabolic_alterations/205085
At the same time, it increased gene expression of antioxidant enzymes. ... insulin sensitivity, and blood pressure is likely attributed to ...
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75 KEYTRUDA® (pembrolizumab)
https://www.keytruda.com/

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76 Gene Mutation Leading To Autism Found to Overstimulate ...
https://neurosciencenews.com/asd-gene-brain-21918/
A gene associated with autism overstimulates brain cells far greater ... human neurons corresponding to synaptic gene expression networks.
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77 Myriad Genetics | Illuminating the path to better health through ...
https://myriad.com/
CONSULT. Ask your doctor about genetic testing to see if you might benefit from a screening. TEST. For testing, a small amount of blood will be drawn, or a ...
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78 Genes, hormones and blood pressure
https://www.genomicseducation.hee.nhs.uk/blog/genes-hormones-and-blood-pressure/
High blood pressure (or hypertension) is a common condition, affecting around 30% of adults. It is normally caused by a combination of genetic ...
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