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1 Treatment of Muckle-Wells syndrome: analysis of two IL-1 ...
https://arthritis-research.biomedcentral.com/articles/10.1186/ar4237
The drug was self-administered by subcutaneous injection once daily. In children with persistent disease activity, the anakinra dose was ...
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2 Muckle-Wells syndrome | DermNet
https://dermnetnz.org/topics/muckle-wells-syndrome
Canakinumab has been FDA-approved for the treatment of adults and children from the age of 4 years affected with Muckle–Wells syndrome. It is a long-acting ...
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3 Muckle-Wells syndrome - About the Disease
https://rarediseases.info.nih.gov/diseases/8472/muckle-wells-syndrome/
IL-1 blockade is an effective and safe treatment in MWS patients. MWS-DAS in combination with MWS inflammatory markers provides an excellent monitoring tool ...
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4 Muckle-Wells syndrome - Cancer Therapy Advisor
https://www.cancertherapyadvisor.com/home/decision-support-in-medicine/pediatrics/muckle-wells-syndrome/
If you are able to confirm that the patient has Muckle-Wells syndrome, what treatment should be initiated? ... Therapies that should be instituted immediately ...
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5 Cryopyrin-associated periodic syndromes - Genetics
https://medlineplus.gov/genetics/condition/cryopyrin-associated-periodic-syndromes/
The group includes three conditions known as familial cold autoinflammatory syndrome type 1 (FCAS1), Muckle-Wells syndrome (MWS), ...
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6 Muckle-Wells syndrome: clinical perspectives | OARRR
https://www.dovepress.com/muckle-wells-syndrome-clinical-perspectives-peer-reviewed-fulltext-article-OARRR
Anakinra has approval in the USA and Europe to be used in infants from 8 months onward at a dose between 1 and 8 mg/kg/day according to clinical ...
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7 Muckle Wells syndrome - Orphanet
https://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=GB&Expert=575
› consor › cgi-bin › OC_Exp
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8 Muckle-Wells Syndrome Across Four Generations in One ...
https://www.frontiersin.org/articles/10.3389/fimmu.2019.00802/full
Therapy with anakinra 100 mg/day subcutaneously led to rapid improvement of all disease parameters within hours to days from the first injection ...
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9 Muckle–Wells syndrome - Wikipedia
https://en.wikipedia.org/wiki/Muckle%E2%80%93Wells_syndrome
Muckle–Wells syndrome (MWS) is a rare autosomal dominant disease which causes sensorineural deafness and recurrent hives, and can lead to amyloidosis.
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10 Muckle-Wells Syndrome - RareShare - Rare Genomics Institute
https://www.raregenomics.org/muckle-wells-syndrome-rareshare-rg
What is Muckle-Wells Syndrome? Muckle-Wells Syndrome is a form of cryopyrin-associated periodic syndrome (CAPS) that is caused by a mutation in the ...
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11 Successful treatment of acute visual loss in Muckle-Wells ...
https://ard.bmj.com/content/64/8/1245
Muckle-Wells syndrome (MWS) is a dominantly inherited autoinflammatory disease characterised by urticarial skin rash, intermittent fever, arthralgia, ...
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12 Cryopyrin-Associated Autoinflammatory Syndrome (CAPS ...
https://www.rheumatology.org/I-Am-A/Patient-Caregiver/Diseases-Conditions/Cryopyrin-Associated-Autoinflammatory-Syndrome-CAPS-Pediatric
In Muckle-Wells syndrome (MWS), patients develop episodic fever, chills, rash, red eyes, joint pain, and severe headaches, often after exposure to cold.
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13 Efficacy, Safety, and Tolerability of ACZ885 in Patients With ...
https://clinicaltrials.gov/ct2/show/NCT00465985
Muckle-Wells Syndrome patients requiring medical intervention either untreated or treated (i.e. under ACZ885, anakinra, or any other investigational IL-1 ...
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14 Muckle-Wells Syndrome - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/immunology-and-microbiology/muckle-wells-syndrome
Use of the IL-1 receptor inhibitor, anakinra, has been highly successful in treatment of all three syndromes. In a study of 18 patients with NOMID, anakinra ...
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15 Muckle-Wells Syndrome (MWS): CAPS NLRP3 Gene
https://autoinflammatory.org/mw.php
The Autoinflammatory Alliance is a non-profit dedicated to increasing awareness, care and treatment for patients with Cryopyrin-Associated Periodic ...
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16 Recovery from deafness in a patient with Muckle‐Wells ...
https://onlinelibrary.wiley.com/doi/10.1002/art.21807
Because an inflammatory syndrome and deafness were still present, treatment with anakinra (100 mg once daily by subcutaneous injection) was ...
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17 The 20 Best Muckle-Wells Syndrome Doctors Near Me
https://www.medifind.com/conditions/muckle-wells-syndrome/3516/doctors
Charité University Medicine Berlin ... Tilmann Kallinich practices in Berlin, Germany. Kallinich is rated as an Elite expert by MediFind in the treatment of ...
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18 Interleukin-1–Receptor Antagonist in the Muckle–Wells ...
https://www.nejm.org/doi/full/10.1056/nejm200306193482523
Treatment with colchicine, low-dose corticosteroids, chlorambucil, antihistamines, dapsone, azathioprine, mycophenolate mofetil, and infliximab ...
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19 Cryopyrin-associated periodic syndromes and related disorders
https://www.uptodate.com/contents/cryopyrin-associated-periodic-syndromes-and-related-disorders?topicRef=116805&source=related_link
It does NOT include all information about conditions, treatments, medications ... Spectrum of clinical features in Muckle-Wells syndrome and ...
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20 List of 4 Muckle Wells Syndrome Medications Compared
https://www.drugs.com/condition/muckle-wells-syndrome.html
Drugs used to treat Muckle Wells Syndrome ; Generic name: rilonacept systemic. Brand name: Arcalyst.
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21 Muckle Wells Syndrome Diseases - il flipper e la nuvola
https://flipper.diff.org/app/items/info/4713
Rilonacept has been approved for the treatment of MWS for adults and children from the age of 12 years. Rilonacept is a fusion protein which ...
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22 Cryopyrin-Associated Periodic Syndromes and Treatment ...
https://oamjms.eu/index.php/mjms/article/view/5024
Cryopyrin-associated periodic syndrome, Familial cold autoinflammatory syndrome, Muckle-Wells syndrome, Neonatal-onset multisystem inflammatory disease, ...
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23 Acupuncture for Muckle-Wells Syndrome | Dr. Windsor
https://www.mdholistics.com/acupuncture_and_natural_medicine/muckle-wells.php
This treatment effect is also observed in pharmaceutical treatments of this condition with interleukin-1 modulating agents such as canakinumab, rilonacept, and ...
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24 unusual phenotype in Muckle–Wells syndrome associated ...
https://academic.oup.com/rheumatology/article/50/2/419/1785508
Following the introduction of anakinra, the ocular and articular symptoms resolved completely over a 1- to 2-month period in each of the four patients and each ...
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25 Muckle-Wells Syndrome in the Setting of Basal Cell Nevus ...
https://www.mdedge.com/dermatology/article/139693/nonmelanoma-skin-cancer/muckle-wells-syndrome-setting-basal-cell-nevus/page/0/1
Treatment with anakinra, rilonacept, and canakinumab generally offers rapid and sustained remission in the majority of MWS patients and helps prevent the ...
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26 Periodic Fever: From Still's Disease to Muckle-Wells Syndrome
https://www.reumatologiaclinica.org/en-periodic-fever-from-still39s-disease-articulo-S2173574318301321
Muckle-Wells syndrome is a systemic autoinflammatory disease included in the group of hereditary periodic febrile syndromes. We report the case of a patient ...
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27 Cryopyrin-Associated Periodic Syndrome: An Update on ...
https://link.springer.com/article/10.1007/s11882-010-0160-9
All patients tolerated the treatment well, except for injection site ... Muckle TJ, Wells M. Urticaria, deafness, and amyloidosis: a new ...
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28 Muckle-Wells Syndrome Effectively Treated with Canakinumab
https://www.karger.com/Article/Pdf/331580
Muckle-Wells Syndrome Effectively Treated with Canakinumab: Is the Recommended Dosing. Schedule Mandatory? Simon M. Mueller Peter Itin Peter ...
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29 Resolution of unilateral sensorineural hearing loss in a ...
https://d-nb.info/1155157389/34
Background: Muckle-Wells syndrome (MWS) is a rare auto-inflammatory disease ... Within 7 months of treatment with Anakinra at 5 mg/kg sc daily, ...
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30 Muckle-Wells Syndrome
https://accessanesthesiology.mhmedical.com/content.aspx?bookid=2674§ionid=220539048
It is characterized by a triad of neonatal onset of cutaneous symptoms, chronic meningitis, and joint manifestations with recurrent fever and inflammation.
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31 Successful treatment of renal amyloidosis due to familial cold ...
https://escholarship.org/content/qt9mt371q2/qt9mt371q2_noSplash_91bc8df72577c810ae498a195de6e925.pdf
Muckle-Wells syndrome, only a small percent- age of patients with FCAS develop progressive chronic kidney disease secondary to AA renal amyloidosis.
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32 Fever, abdominal pain, serositis, arthralgia, hearing loss ...
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)02139-5/fulltext
Fever, abdominal pain, serositis, arthralgia, hearing loss, proteinuria, and a family history: Muckle Wells syndrome ... A 53-year-old man ...
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33 Muckle-Wells Syndrome — A Diagnosis Frequently Delayed
https://www.jwatch.org/na35207/2014/07/23/muckle-wells-syndrome-diagnosis-frequently-delayed
Muckle-Wells syndrome (MWS) is an inherited autoinflammatory syndrome that can present in childhood or adulthood.
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34 Muckle-Wells Syndrome (MWS) - Patient Worthy
https://patientworthy.com/muckle-wells-syndrome/
› muckle-wells-syndrome
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35 Treatment of Muckle-Wells syndrome: Analysis of two IL-1 ...
https://www.researchgate.net/publication/236966876_Treatment_of_Muckle-Wells_syndrome_Analysis_of_two_IL-1-blocking_regimens
Objectives Muckle-Wells syndrome (MWS) is an autoinflammatory disease characterized by excessive interleukin-1 (IL-1) release, resulting in ...
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36 Research: Muckle-Wells syndrome - Rare Disease InfoHub
https://rarediseases.oscar.ncsu.edu/disease/muckle-wells-syndrome/research/
It may take many years to treat enough patients to determine if a treatment is effective. The FDA, patient communities, legislation, and the drug companies are ...
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37 muckle-wells syndrome mws: Topics by Science.gov
https://www.science.gov/topicpages/m/muckle-wells+syndrome+mws.html
Familial cold autoinflammatory syndrome, Muckle-Wells syndrome (MWS), and chronic, ... Treatment was well tolerated, with no injection site reactions and no ...
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38 CAPS Treatment Glossary | ILARIS® (canakinumab)
https://www.ilaris.com/caps/caps-glossary
Cryopyrin-Associated Periodic Syndromes: a group of rare and genetic diseases that includes Familial Cold Autoinflammatory Syndrome (FCAS) and Muckle-Wells ...
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39 Cryopyrin Associated Periodic Syndromes (CAPS) (CINCA ...
https://www.printo.it/pediatric-rheumatology/GB/info/17/Cryopyrin-Associated-Periodic-Syndromes-(CAPS)-(CINCA-Muckle-Wells-FCAS)
These attacks are self-limiting (meaning that they resolve without treatment). Patients frequently report a pattern of feeling well in the morning after a warm ...
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40 Diagnosis and Management of the Cryopyrin-Associated ...
https://www.mdpi.com/2077-0383/10/1/128/htm
MWS was first described in 1962 by Muckle and Wells as a syndrome of ... hearing loss in a patient with Muckle-Wells syndrome treated with anakinra. Klin.
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41 Thyroid and renal amyloidosis secondary to cryopyrin ...
https://www.revistanefrologia.com/en-thyroid-renal-amyloidosis-secondary-cryopyrin-articulo-X2013251413002829
The patient has been on treatment for approximately 2 months with canakinumab, a monoclonal anti-IL-1β antibody, which has produced a complete disappearance of ...
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42 Muckle–Wells syndrome: A rare cryopyrinopathy
https://www.jaad.org/article/S0190-9622(16)00708-8/fulltext
Muckle–Wells syndrome (MWS) is a rare autosomal dominant disease caused by a ... Treatment with an IL-1 receptor antagonist has demonstrated vast ...
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43 Muckle–Wells syndrome: another cause of acute anterior uveitis
https://www.nature.com/articles/6702704
Fundus examination was unremarkable. The anterior uveitis resolved with standard treatment and the acuity recovered to 6/6. She presented again ...
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44 Hereditary Cryopyrin-Associated Periodic Syndromes ...
https://www.merckmanuals.com/professional/pediatrics/hereditary-periodic-fever-syndromes/hereditary-cryopyrin-associated-periodic-syndromes-cryopyrinopathies
... Muckle-Wells syndrome, and neonatal-onset multisystem autoinflammatory disease. Diagnosis is clinical. Treatment is with interleukin-1 beta inhibitors.
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45 Current treatment recommendations and considerations for ...
https://www.tandfonline.com/doi/full/10.1586/1744666X.2015.1077702
Anti-IL-1 drugs have shown remarkable efficacy in treating CAPS symptoms and ... to Muckle–Wells syndrome (MWS); to the most severe form, ...
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46 Bridging the Gap between the Clinician and the Patient with ...
https://journals.sagepub.com/doi/pdf/10.1177/039463201102400402
diseases, namely familial cold auto-inflammatory syndrome, Muckle-Wells ... Onset occurs early in childhood, and life-long therapy with interleukin-l ...
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47 Cryopyrin Associated Periodic Syndrome (Familial Cold ...
https://www.dermatologyadvisor.com/home/decision-support-in-medicine/dermatology/cryopyrin-associated-periodic-syndrome-familial-cold-urticaria-familial-cold-autoinflammatory-syndrome-muckle-wells-syndrome-neonatal-onset-multisystem-inflammatory-disorder-chronic-infantile-neu/
The first-line choice of therapy would probably be canakinumab or rilonacept, as these are licensed for CAPS and may be more easily obtained ...
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48 Muckle-Wells syndrome in an Indian family associated with ...
https://www.jpgmonline.com/article.asp?issn=0022-3859;year=2015;volume=61;issue=2;spage=120;epage=122;aulast=Abdulla
Muckle - Wells syndrome (MWS) is a rare autosomal dominant disease that belongs to a group of hereditary periodic fever syndromes.
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49 A rare hereditary disease: Muckle-Wells syndrome
https://www.pagepress.org/journals/index.php/rr/article/view/6535
› index.php › article › view
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50 Cryopyrinopathies: Update on Pathogenesis and Treatment
https://www.medscape.org/viewarticle/578167
Cryopyrinopathies are a group of rare autoinflammatory diseases that includes familial cold autoinflammatory syndrome, Muckle–Wells syndrome and chronic ...
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51 Muckle-Wells Syndrome (MWS) - MalaCards
http://www.malacards.org/card/muckle_wells_syndrome
Drugs for Muckle-Wells Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB): ; 17, calcium channel blockers ; 18, Platelet Aggregation ...
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52 Treatment of Muckle-Wells syndrome: analysis of two IL ... - Gale
https://go.gale.com/ps/i.do?id=GALE%7CA534783432&sid=googleScholar&v=2.1&it=r&linkaccess=fulltext&issn=14786354&p=AONE&sw=w
Muckle-Wells syndrome (MWS) is an autoinflammatory disease characterized by excessive interleukin-1 (IL-1) release, resulting in recurrent fevers, ...
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53 Muckle-Wells Syndrome Effectively Treated with Canakinumab
https://www.semanticscholar.org/paper/Muckle-Wells-Syndrome-Effectively-Treated-with-Is-Mueller-Itin/70153ff8b20eb6dd7777564438681b4d0fcc340b
We report on two half-siblings with Muckle-Wells syndrome who were successfully treated with the interleukin-1 beta antibody canakinumab.
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54 Cryopyrin-Associated Periodic Syndromes (CAPS)
https://www.arthritis.org/diseases/cryopyrin-associated-periodic-syndrome
Muckle-Wells Syndrome. This disease is characterized by symptoms that come and go, and include rash, red eyes, joint pain and severe headaches with vomiting ...
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55 Inflammasome-Mediated Disease Animal Models Reveal ...
https://www.cell.com/immunity/pdf/S1074-7613(09)00233-7.pdf
Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. Nat. Genet. 29, 301–305.
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56 Cryopyrin Associated Periodic Syndrome
https://www.immunodeficiencysearch.com/cryopyrin-associated-periodic-syndrome
Muckle-Wells Syndrome (MWS) This syndrome is characterized by episodic attacks with fever and urticaria-like rash, arthralgia, and progressive sensorineural ...
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57 CAP-Syndrome: Response to Treatment With Canakinumab
https://iovs.arvojournals.org/article.aspx?articleid=2148388
CAPS encompasses three different entities: familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS) and chronic infantile neurological ...
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58 KEGG DISEASE: Muckle-Wells syndrome
https://www.genome.jp/entry/H02555
Muckle-Wells syndrome (MWS) is a rare inherited autoinflammatory disease characterized by fevers, rashes, arthralgia, conjunctivitis, and sensorineural ...
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59 Skyelah's Story: Living with Muckle Wells Syndrome
https://complexchild.org/articles/2017-articles/december/muckle-wells/
Muckle Wells Syndrome is also known as urticaria-deafness-amyloidosis syndrome (UDA), a rare autosomal dominant disease which causes ...
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60 Cryopyrin Associated Periodic Syndromes C A P S IL 1 ...
https://www.molinahealthcare.com/providers/wa/medicaid/resource/PDF/periodic-syndromes-mcp110.pdf
Treatment of Cryopyrin-Associated Periodic Syndromes (CAPS), including Familial Cold Auto-inflammatory Syndrome. (FCAS) and Muckle-Wells Syndrome (MWS) in ...
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61 Phenotype, Genotype, and Sustained Response to Anakinra ...
https://jamanetwork.com/journals/jamadermatology/fullarticle/410288
Conclusions Anakinra therapy was well tolerated and has sustained efficacy on ... Muckle-Wells syndrome, described in 1962, is another autosomal dominant ...
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62 Four cases of Muckle-Wells syndrome within the same family
https://www.scielo.br/j/abd/a/gL5ymWfgyBzsFSTHQHjdLBh/?lang=en
Muckle-Wells syndrome is a rare autosomal dominant disease that belongs to a group of hereditary febrile syndromes. It is characterized by recurrent and self- ...
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63 Cryopyrin-Associated Periodic Syndromes - The Rheumatologist
https://www.the-rheumatologist.org/article/cryopyrin-associated-periodic-syndromes-difficult-to-recognize-diagnose-treat/?singlepage=1
He stumbled across Muckle‑Wells syndrome, and it seemed to explain many of ... Several days after commencing treatment with the monoclonal ...
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64 Muckle-Wells Syndrome: Symptoms, Diagnosis and Treatment
https://www.symptoma.com/en/info/muckle-wells-syndrome
Muckle Wells syndrome (MWS) is a rare genetic disorder that causes recurrent episodes of fever, skin rash, arthralgia/arthritis, and inflammation of the eye ...
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65 FDA Approves “Icy Fire” Drug Based on UC San Diego ...
https://health.ucsd.edu/news/2008/pages/3-5-arcalyst.aspx
... the treatment Cyropyrin-Associated Periodic Syndromes (CAPS), including Familial Cold Auto-inflammatory Syndrome (FCAS) and Muckle-Wells ...
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66 MUCKLE-WELLS SYNDROME CAUSED BY A NEW ...
https://ter-arkhiv.ru/0040-3660/article/view/31064
MUCKLE-WELLS SYNDROME CAUSED BY A NEW CRYOPIRIN MUTATION: EFFECTIVE TREATMENT WITH INTERLEUKIN-1 ANTAGONIST.
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67 NLRP3 E311K mutation in a large family with Muckle-Wells ...
https://cyberleninka.org/article/n/1022001
Patients were treated with the IL-1 inhibitors Anakinra or Canakinumab. Results: All 13 clinically affected patients were heterozygous carriers of the amino ...
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68 CNS Manifestations of Patients with Muckle-Wells Syndrome
https://acrabstracts.org/abstract/cns-manifestations-of-patients-with-muckle-wells-syndrome/
Muckle-Wells syndrome (MWS) is a rare autosomal dominant disease which causes sensorineural deafness, recurrent hives, and joint pain.
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69 Cryopyrin-Associated Autoinflammatory Syndromes
https://www.news-medical.net/health/Cryopyrin-Associated-Autoinflammatory-Syndromes.aspx
Muckle-Wells syndrome ... In this condition the patient has regular bouts of fever with chills, rashes, red eyes, joint pain and intense headache.
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70 Canakinumab (Subcutaneous Route) - Mayo Clinic
https://www.mayoclinic.org/drugs-supplements/canakinumab-subcutaneous-route/description/drg-20073102
Canakinumab injection is used to treat cryopyrin-associated periodic syndromes (CAPS), including familial cold autoinflammatory syndrome (FCAS) and Muckle-Wells ...
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71 Muckle Wells Syndrome|Causes|Symptoms|Treatment
https://www.epainassist.com/genetic-disorders/muckle-wells-syndrome
The diagnosis of Muckle-Wells Syndrome is made by looking at the presenting features of the patient along with certain specialized tests. A ...
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72 Additional Benefit of Canakinumab on Proteinuria in a Case ...
https://www.archivesofrheumatology.org/full-text-pdf/1083
Muckle-Wells Syndrome in Remission Under Anakinra ... 1Department of Internal Medicine, Division of Rheumatology, Trakya University Medical ...
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73 Cryopyrin-associated Periodic Syndrome (CAPS) Treatment ...
http://saidsupport.org/cryopyrin-associated-periodic-syndrome-caps-treatment-guidelines-studies-resources/
There are three forms of CAPS, familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MES), and neonatal-onset multisystem ...
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74 Does this patient have periodic fever syndrome? - RCP Journals
https://www.rcpjournals.org/content/clinmedicine/11/4/396
Treatment options for periodic fever syndromes (PFS). ... New mutations of CIAS1 that are responsible for Muckle-Wells syndrome and familial cold urticaria: ...
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75 Cryopyrin-associated periodic syndromes Treatment Bangalore
https://www.arthritisfoundationasia.com/cryopyrin-associated-periodic-syndromes.html
Muckle-Wells syndrome is characterized by symptoms that come and go, including skin rash, red eyes, joint pain and severe headaches with vomiting.
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76 Chronic urticaria with inflammation
https://www.ejinme.com/article/S0953-6205(20)30416-7/fulltext
A NOD-like receptor protein 3 (NLRP3) mutation was detected, and Muckle–Wells syndrome (MWS) was diagnosed. After canakinumab treatment, the ...
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77 'Maybe this will help other kids' | Health Beat
https://healthbeat.spectrumhealth.org/maybe-this-will-help-other-kids/
Fourteen-year-old Tara Sweet noticed her COVID-19 symptoms improving ... Hospital who oversees her treatment for Muckle-Wells syndrome.
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78 challenges-in-diagnosing-muckle-wells-syndrome-identifying ...
https://www.rareconnect.org/uploads/documents/challenges-in-diagnosing-muckle-wells-syndrome-identifying-two-distinct-phenotypes.pdf
Clinical recognition remains essential. Early diagnosis and timely onset of effective therapy are crucial for the prevention of irreversible organ damage.
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79 Muckle-Wells syndrome - bionity.com
https://www.bionity.com/en/encyclopedia/Muckle-Wells_syndrome.html
MWS was first described in 1962 by Thomas James Muckle and Michael Vernon Wells. ... Treatment of MWS with anakinra, an interleukin 1 receptor antagonist, can ...
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80 e109.full-text.pdf
https://nn.neurology.org/content/nnn/2/4/e109.full-text.pdf
as well as the diagnosis of MS. ... 5 of 9 treated patients (56%) responded to anti–interleukin-1 therapy. ... Muckle-Wells syndrome (MWS),3.
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81 9860-a-retrospective-patient-chart-review-and-survey-in ...
https://jheor.org/article/9860-a-retrospective-patient-chart-review-and-survey-in-patients-with-cryopyrin-associated-periodic-syndromes-treated-with-anakinra.pdf
Cryopyrin-associated Periodic Syndromes Treated with Anakinra ... spectrum from familial cold autoinflammatory syndrome (FCAS) to Muckle-Wells syndrome.
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82 Public summary of opinion on orphan designation Rilonacept ...
https://www.ema.europa.eu/en/documents/orphan-designation/eu/3/07/456-public-summary-positive-opinion-orphan-designation-rilonacept-treatment-cryopirin-associated_en-0.pdf
Rilonacept for the treatment of cryopirin-associated periodic syndromes. (Familial Cold Urticaria Syndrome (FCUS), Muckle-Wells Syndrome ...
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83 Periodic Fever Syndrome - Cleveland Clinic
https://my.clevelandclinic.org/health/articles/17354-periodic-fever-syndrome
How is FMF treated? FMF cannot be cured, but it can be well controlled with life-long use of colchicine. In this way, episodes can usually be ...
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84 Mast cells mediate neutrophil recruitment and vascular ...
https://rupress.org/jem/article/206/5/1037/40536/Mast-cells-mediate-neutrophil-recruitment-and
H1 antihistamines have remained the first line of treatment because histamine ... inheritance in men number [MIM] 120100), Muckle-Wells syndrome (MWS; ...
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85 Inzomelid completes Phase I studies and shows positive ...
https://www.biospace.com/article/releases/inzomelid-completes-phase-i-studies-and-shows-positive-results-in-the-treatment-of-cryopyrin-associated-periodic-syndrome-caps-/
... Phase I studies and shows positive results in the treatment of ... Muckle-Wells syndrome (MWS) and familial cold autoinflammatory ...
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86 ARCALYST(TM) (rilonacept), First and Only FDA-approved ...
https://investor.regeneron.com/news-releases/news-release-details/arcalysttm-rilonacept-first-and-only-fda-approved-treatment
... treatment of Cryopyrin-Associated Periodic Syndromes (CAPS), including Familial Cold Auto-inflammatory Syndrome (FCAS) and Muckle-Wells ...
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87 Muckle-Wells Syndrome: I'll never know for sure, but I think my ...
https://weareunsinkable.com/muckle-wells-syndrome-ill-never-know-for-sure-but-i-think-my-daughter-saved-my-life/
Even though we have to take injections of this biologic medicine for the rest of our lives in order to mask our symptoms and stave off ...
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88 Lessons From the Misdiagnosis of Cryopyrin-Associated ...
https://journals.lww.com/jclinrheum/Fulltext/2021/12003/Lessons_From_the_Misdiagnosis_of.55.aspx
... familial cold-induced autoinflammatory syndrome, Muckle-Wells syndrome, ... After 15 months of antituberculosis treatment, the fever and rash were not ...
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89 Muckle–Wells syndrome | Top Authors | Related Topics
https://typeset.io/topics/muckle-wells-syndrome-3skterup?paper_page=5
TL;DR: A 22-year-old patient with MWS who had deafness and a high serum level of C-reactive protein (CRP) was treated with anakinra, and she recovered from ...
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90 Autoinflammatory syndromes: Fever is not always a sign of ...
https://www.ccjm.org/content/ccjom/79/8/569.full.pdf
tion, and treatment of several of these relatively recently ... Early recognition and treatment with immunoregulatory ... MWS—Muckle-Wells syndrome.
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91 E13/S(HSS)/b - NHS England
https://www.england.nhs.uk/wp-content/uploads/2013/06/e13-cryopyrin-ass-periodic-syn.pdf
Canakinumab treatment was well tolerated, not associated with any deaths and ... Muckle-Wells syndrome) is one of many inherited diseases supported by the ...
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92 Identi cation of a Variant in NLRP3 Gene in a Patient with ...
https://www.researchsquare.com/article/rs-1875943/v1.pdf
diagnosed with Muckle-Wells syndrome. He was subsequently treated with oral thalidomide at 12.5 mg, twice a day.
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93 Muckle Wells Syndrome | Bone and Spine
https://boneandspine.com/muckle-wells-syndrome/
Muckle Wells syndrome is a rare autosomal dominant disease which results in sensorineural deafness, recurrent hives, amyloidosis, and arthritis.
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94 Autoinflammatory disease: New mouse models and therapies
https://www.jacionline.org/article/S0091-6749(19)31404-6/abstract
FCAS, Familial cold autoinflammatory syndrome; MWS, Muckle Wells ... Yet it is clear that the treatment of CAPS is not the ultimate goal.
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95 Interleukin-1–Receptor Antagonist in the Muckle–Wells ...
https://discovery.ucl.ac.uk/8603/1/8603.pdf
recently identified as the cause of the Muckle–Wells syndrome and the familial cold autoinflammatory ... phrotic syndrome may resolve.4 Treatment with.
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96 Cryopyrin-associated periodic syndromes and ... - medilib
https://www.medilib.ir/uptodate/show/5585
Treatment of FCAS and other cryopyrinopathies is discussed below. (See 'Treatment of cryopyrinopathies' below.) Muckle-Wells syndrome — Muckle-Wells ...
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