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1
https://www.washington.edu/news/2012/11/08/extra-chromosome-21-removed-from-down-syndrome-cell-line/
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2
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3
https://blogs.biomedcentral.com/on-medicine/2017/12/04/crisprcas9-gene-editing-can-be-used-to-eliminate-entire-chromosomes-a-qa/
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4
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6
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8
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9
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10
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11
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12
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13
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19
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20
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21
https://www.statnews.com/2022/01/06/provocative-new-findings-suggest-surprising-cause-of-down-syndrome/
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22
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23
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24
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25
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26
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27
https://www.cell.com/cell/pdf/S0092-8674(20)31389-1.pdf
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28
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29
https://www.frontiersin.org/articles/10.3389/fped.2021.592571/full
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30
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31
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32
https://www.nytimes.com/2020/10/31/health/crispr-genetics-embryos.html
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33
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34
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https://www.genome.gov/news/news-release/Sequencing-all-24-human-chromosomes-uncovers-rare-disorders
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40
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41
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42
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https://www.pnas.org/doi/10.1073/pnas.1918859117
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44
https://www.quora.com/What-will-happen-if-a-chromosome-is-removed-from-a-cell
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48
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49
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51
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https://www.verywellfamily.com/chromosomal-abnormality-2371605
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55
https://www.ksat.com/health/2014/11/17/stem-cells-to-repair-broken-chromosomes-medicines-next-big-thing/
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56
http://www.intellectualdisability.info/conditions-associated-with-intellectual-disability/articles/downs-syndrome
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58
https://theconversation.com/the-y-chromosome-is-disappearing-so-what-will-happen-to-men-90125
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59
https://sitn.hms.harvard.edu/flash/2014/crispr-a-game-changing-genetic-engineering-technique/
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64
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65
https://www.fpwr.org/genetic-therapy-for-prader-willi-syndrome
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66
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https://www.mayoclinic.org/diseases-conditions/klinefelter-syndrome/diagnosis-treatment/drc-20353954
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70
https://www.geneticsandsociety.org/internal-content/what-human-gene-editing
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71
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https://phys.org/news/2022-08-sustainable-chromosome-mice.html
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https://www.newscientist.com/article/dn16934-girl-with-y-chromosome-sheds-light-on-maleness/
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75
https://www.irishtimes.com/news/health/scientists-find-way-to-switch-off-chromosome-that-causes-down-syndrome-1.1467559
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76
https://www.healthline.com/health/xyy-syndrome
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https://www.embopress.org/doi/10.15252/emmm.201607284
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78
https://elifesciences.org/articles/56223
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https://www.theatlantic.com/science/archive/2019/12/men-lose-y-chromosomes-cells-they-age/603013/
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80
https://www.karger.com/Article/Fulltext/330627
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82
https://www.synthego.com/blog/gene-drive-crispr
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https://www.smithsonianmag.com/science-nature/y-chromosome-may-be-doomed-180967887/
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https://learn.genetics.utah.edu/content/disorders/whatispgt
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https://www.medicalnewstoday.com/articles/what-chromosomes-are-affected-by-edwards-syndrome
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https://news.berkeley.edu/2014/01/09/study-dispels-theories-of-y-chromosomes-demise/
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https://emedicine.medscape.com/article/273415-overview
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https://www.economist.com/science-and-technology/2014/03/27/diy-chromosomes
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https://www.nbcnews.com/healthmain/could-it-be-cure-breakthrough-prompts-down-syndrome-soul-searching-6c10879213
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https://www.khanacademy.org/science/biology/dna-as-the-genetic-material/dna-replication/a/dna-proofreading-and-repair
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