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1 S100A4 in cancer progression and metastasis - NCBI
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641208/
CONCLUSION: The expression of protein S100A4 is associated with tumor recurrence and poor overall survival in patients with colorectal cancer. Keywords: S100A4, ...
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2 Prognostic significance of calcium-binding protein S100A4 in ...
https://www.gastrojournal.org/article/S0016-5085(02)00281-0/fulltext
S100A4 has been reported to be associated with invasion and metastasis; however, no data are available on its prognostic value in colorectal carcinoma.
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3 S100A4 | Cancer Genetics Web - CancerIndex
http://www.cancerindex.org/geneweb/S100A4.htm
S100 calcium binding protein A4 (S100A4) is a well‑established tumor metastasis mediator in various malignancies, including endometrial cancer (EC). However, ...
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4 Downregulation of S100A4 expression by RNA interference ...
https://www.spandidos-publications.com/10.3892/or.2011.1598
Our previous study found that the overexpression of S100A4 existed more frequently in colorectal cancer patients with advanced stage, lymph node ...
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5 Src kinase pathway is involved in NFAT5-mediated S100A4 ...
https://journals.physiology.org/doi/full/10.1152/ajpcell.00407.2010
To study the regulation of S100A4 by NFAT5 in a more readily inducible model, colon cancer cells were subjected to hyperosmotic stress. We found that S100A4 ...
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6 CLINICAL AND PATHOLOGICAL SIGNIFICANCE OF S100A4 ...
https://dergipark.org.tr/tr/download/article-file/272565
confirm the practicality of using S100A4 expression to augment patient treatment. Key words: Colon cancer, S100A4, calcium binding proteins.
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7 S100A4 in Cancer Metastasis: Wnt Signaling-Driven ... - MDPI
https://www.mdpi.com/2072-6694/8/6/59
Elevated S100A4 expression is altering the genetic expression pattern of cells, leading to a more malignant phenotype [38]. For CRC patients, higher tumor ...
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8 Novel Effect of Antihelminthic Niclosamide on S100A4 ...
https://academic.oup.com/jnci/article/103/13/1018/899777
AbstractBackground. Metastasis formation in colon cancer severely reduces the survival rate in patients. S100A4, a calcium-binding protein, is implicated in ...
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9 LIM and SH3 Protein 1 Induces TGFβ-Mediated Epithelial ...
https://aacrjournals.org/clincancerres/article/20/22/5835/117243/LIM-and-SH3-Protein-1-Induces-TGF-Mediated
Our present results reveal that LASP1 induces a TGFβ-mediated epithelial–mesenchymal transition in human colorectal cancer by regulating S100A4 expression.
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10 Prognostic significance of S100A4 expression in stage II and ...
https://onlinelibrary.wiley.com/doi/full/10.1002/cam4.766
Current clinical algorithms are unable to precisely predict which colorectal cancer patients would benefit from adjuvant chemotherapy, ...
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11 S100A4-induced cell motility and metastasis is restricted by ...
https://www.molbiolcell.org/doi/10.1091/mbc.e10-09-0739
In colon cancer cells calcimycin treatment reduced S100A4 mRNA and protein expression in a dose- and time-dependent manner. S100A4-induced ...
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12 Molecular Mechanisms by Which S100A4 Regulates the ...
https://www.frontiersin.org/articles/10.3389/fonc.2020.00182/full
Molecular Mechanisms by Which S100A4 Regulates the Migration and Invasion of PGCCs With Their Daughter Cells in Human Colorectal Cancer.
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13 S100A4 over-expression underlies lymph node metastasis ...
https://www.wjgnet.com/1007-9327/full/v17/i1/69.htm
AIM: To develop lymph node metastasis (LNM)-associated biomarkers for colorectal cancer (CRC) using quantitative proteome analysis. METHODS: ...
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14 EMMPRIN is associated with S100A4 and predicts patient ...
https://www.nature.com/articles/bjc2012293
EMMPRIN is a promising prognostic biomarker in colorectal cancer, ... cancer patients, and associations with expression of S100A4, ...
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15 Vascular Invasion and Stromal S100A4 Expression at the ...
https://www.jcancer.org/v08p1552.htm
Keywords: colorectal cancer, prognostic marker, S100A4, tumor budding, vascular invasion. Introduction. The tumor node metastasis (TNM) staging system proposed ...
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16 S100A4 promotes colon inflammation and colitis-associated ...
https://www.tandfonline.com/doi/full/10.1080/2162402X.2018.1461301
Chronic inflammation is a major driving force for the initiation and progression of many types of cancers, including colorectal cancer (CRC), ...
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17 S100A4 may be a good prognostic marker and a therapeutic target ...
https://dataverse.harvard.edu/dataset.xhtml;jsessionid=ee3375e6fda89d7cb9721fa555db?persistentId=doi%3A10.7910%2FDVN%2FEMCRNZ&version=&q=&fileTypeGroupFacet=&fileAccess=Public&fileSortField=date
Background: Globally, the colorectal cancers rank the third in terms of cancer incidence and rank the fourth in cancer-associated deaths. S100A4 ...
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18 S100A4 May Be a Good Prognostic Marker and a Therapeutic ...
https://pdfs.semanticscholar.org/d6f7/52e797b7c353431084e41032ee4bac6fe9ce.pdf
Tissue samples of colon cancer from 148 patients who underwent ... Expression of the S100A4 protein in colon cancers may be an indicator of.
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19 Overexpressed methyltransferase-like 1 (METTL1) increased ...
https://www.aging-us.com/article/102575/text
Overexpressed methyltransferase-like 1 (METTL1) increased chemosensitivity of colon cancer cells to cisplatin by regulating miR-149-3p/S100A4/p53 axis ...
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20 Diagnostic and Prognostic Value of Metastasis Inducer ...
https://www.jmdjournal.org/article/S1525-1578(10)00057-7/pdf
Diagnostic and Prognostic Value of Metastasis. Inducer S100A4 Transcripts in Plasma of Colon,. Rectal, and Gastric Cancer Patients.
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21 Release of S100A4 from Normal Blood Cells Prohibits the Use ...
https://www.karger.com/Article/Abstract/77721
The metastasis-related protein S100A4 is released from tumor cells, and since it is highly expressed in colorectal cancer (CRC), it could be a potential ...
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22 Significance of a calcium-binding protein S100A14 expression ...
https://jgo.amegroups.com/article/view/60314/html
The overexpression of S100A4 leads to poor prognoses of colon and breast cancers (8,9). In addition, S100A6 is related to several kinds of malignant ...
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23 Nuclear S100A4 is a novel prognostic marker in colorectal ...
https://www.ejcancer.com/article/S0959-8049(10)00691-X/fulltext
Current staging classifications in colorectal cancer are not able to accurately predict patient outcome, and the need for novel prognostic ...
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24 S100A4 over-expression underlies lymph node metastasis ...
https://www.researchgate.net/publication/49739838_S100A4_over-expression_underlies_lymph_node_metastasis_and_poor_prognosis_in_colorectal_cancer
PDF | To develop lymph node metastasis (LNM)-associated biomarkers for colorectal cancer (CRC) using quantitative proteome analysis.
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25 S100A4 promotes colorectal carcinoma growth by enhancing ...
https://www.researchsquare.com/article/rs-13496/v1.pdf
The aim of this study was to examine the role of S100A4 in aerobic glycolysis in colorectal cancer (CRC). Methods We investigated S100A4 ...
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26 Circulating MACC1 Transcripts in Colorectal Cancer Patient ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0049249
MACC1 is a strong prognostic biomarker for colon cancer ... Combining MACC1 with circulating transcripts of the metastasis gene S100A4, ...
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27 Overexpression of protein S100A4 is independently ... - Springer
https://link.springer.com/article/10.1007/s00384-012-1469-8
Overexpression of protein S100A4 is independently associated with overall survival in stage C colonic cancer but only in cytoplasm at the ...
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28 Overexpression of S100A4 is closely associated with ...
https://europepmc.org/article/med/16097057
Moderate to strong cytoplasmic expression of S100A4 was seen in 69 (55.6%) of the 124 colorectal carcinoma tissue specimens. S100A4 expression was detected ...
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29 microRNAs and Corresponding Targets Involved in Metastasis ...
https://cgp.iiarjournals.org/content/17/5/453
: Prognostic significance of calcium-binding protein S100A4 in colorectal cancer. Gastroenterology 123: 1478-1484, 2002. PMID: 12404222.
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30 The metastasis-associated gene S100A4 is a novel target of β ...
https://www.mdc-berlin.de/highlights/archive/2006/highlight17
Our aim was to elucidate the impact of gain-of-function beta-catenin on the metastasis-associated gene S100A4 in human colon cancer cell lines and tumors.
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31 Activation of the PI3K/Akt/mTOR/p70S6K Pathway is Involved ...
https://www.medsci.org/v11p0841.htm
Keywords: colorectal cancer, S100A4, PI3K/Akt/mTOR/p70S6K, viability, ... Colorectal cancer (CRC) is the most predominant malignant digestive tumor ...
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32 The metastasis-associated gene S100A4 is a novel target of ...
https://ncifrederick.cancer.gov/ScientificLibrary/Publication/Approved.aspx?Id=6452
Furthermore, S100A4 mRNA expression was increased in primary colon cancers, which later developed distant metastases, compared to non-metastasizing tumors.
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33 S100A4-induced cell motility and metastasis is restricted by ...
https://core.ac.uk/download/pdf/300321606.pdf
ABSTRACT The calcium-binding protein S100A4 is a central mediator of metastasis forma- tion in colon cancer. S100A4 is a target gene of the Wnt/β-catenin ...
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34 Prognostic significance of S100A4 expression in biliary tract ...
https://ascopubs.org/doi/10.1200/jco.2010.28.15_suppl.e14620
Background: S100A4, the S100 family of calcium-binding protein, has been shown to be related with cell proliferation and invasiveness of cancer ...
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35 S100A4 antibody (16105-1-AP) - Proteintech
https://www.ptglab.com/products/S100A4-Antibody-16105-1-AP.htm
S100A4 antibody for FC, IF, IHC, WB, ELISA and reacts with human, mouse. ... Immunohistochemistry (IHC) staining of human colon cancer tissue using S100A4 ...
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36 New insights into S100A4-induced colon cancer metastasis
https://edoc.hu-berlin.de/bitstream/handle/18452/16965/sack.pdf?sequence=1
S100A4 and cell growth. 30. 1.4.8. S100A4 drives metastasis formation in vivo. 31. 1.4.9. S100A4 expression correlates with metastasis in colon cancer ...
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37 Expression of S100A4 in cancer - The Human Protein Atlas
https://www.proteinatlas.org/ENSG00000196154-S100A4/pathology
Expression of S100A4 (18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98) in cancer tissue. ... lung, pancreatic, gastric, colorectal and urothelial cancers.
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38 Clinicopathological and prognostic ... - CyberLeninka
https://cyberleninka.org/article/n/1410606.pdf
of S100A4 overexpression in colorectal cancer: a meta-analysis. Yanqiong Liu1†, Weizhong Tang2†, Jian Wang1, Li Xie1, Taijie Li1, Yu He1, ...
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39 S100A4 and Metastasis - The American Journal of Pathology
https://ajp.amjpathol.org/article/S0002-9440(10)60366-5/fulltext
in a panel of primary tumor samples from patients with colorectal cancer using immunohistochemistry and subcellular fractionation experiments, and this ...
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40 Prestige Antibodies® in Colorectal Cancer Research
https://www.sigmaaldrich.cn/deepweb/assets/sigmaaldrich/marketing/global/documents/250/257/atlas-antibodies-brochure-colorectal-ms.pdf
on colon cancer relevance for the corresponding target protein. ... S100A4. Anti-S100A4. AMAb90599. IHC,WB,ICC-IF. HSPA1A. Anti-HSPA1A. HPA052504.
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41 S100A4 over-expression underlies lymph node ... - NET
https://f6publishing.blob.core.windows.net/d8de2603-7958-45cc-8709-c41c87583152/WJG-17-69.pdf
S100A4 over-expression underlies lymph node metastasis and poor prognosis in colorectal cancer. Li-Yong Huang, Ye Xu, Guo-Xiang Cai, ...
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42 Clinicopathological Significance of S100A4 Expression in Non ...
https://www.jpatholtm.org/upload/pdf/kjp-44-5-477.pdf
tumors. The aim of this study was to investigate whether or not S100A4 plays an important ... and overall survival in colonic AD30 and melanoma.23 Several.
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43 S100A4 Is a Strong Negative Prognostic Marker and Potential ...
https://mdpi-res.com/d_attachment/cells/cells-11-01056/article_deploy/cells-11-01056.pdf
Yet, S100A4 expression in gastric cancer has been analyzed ... colon cancer cells in vitro and metastasis development in vivo [18–20].
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44 A Meta-Analysis - Zhian Ling, Ruolin Li, 2014 - SAGE Journals
https://journals.sagepub.com/doi/10.5301/jbm.5000054?icid=int.sj-abstract.similar-articles.2
PurposesFor several years S100A4 has been implicated in tumor progression ... of metastasis-associated in colon cancer-1 in gastric cancer: A meta-analysis.
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45 EMMPRIN is associated with S100A4 and ... - ScienceOpen
https://www.scienceopen.com/document?vid=7f72bd88-93e8-428c-8aa8-8f4f83892d1a
Background: Proteolytic enzymes and their regulators have important biological roles in colorectal cancer by stimulating invasion and metastasis, ...
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46 intervention strategies for S100A4-induced metastasis in ...
http://www.gpb.sav.sk/FI-2009/F55.pdf
Colon cancer is still a burden mainly due to metastasis formation. ... Keywords: Colorectal cancer — Metastasis — S100A4 — Wnt signaling — β-catenin.
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47 Impact of S100A4 Expression on Clinicopathological ...
https://www.hindawi.com/journals/dm/2016/8137378/
S100A4 expression represents a potential marker for lymph node metastasis of ... 11] and particularly gastrointestinal cancers, including colorectal [.
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48 Nuclear localization of the metastasis-related protein S100A4 ...
https://pure.fo/en/publications/nuclear-localization-of-the-metastasis-related-protein-s100a4-cor
The nuclear localization of S100A4 in colorectal cancer and its relationship to tumour stage suggest that this protein may be involved in gene regulatory ...
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49 S100A4 regulation and function - UTMB Health SHARED Home
https://utmb-ir.tdl.org/handle/2152.3/778
This dissertation focuses on exploring the mechanisms of S100A4 regulation by integrin α6β4 in breast cancer cells, and hyperosmotic stress response in colon ...
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50 Podoplanin - :: JKMS :: Journal of Korean Medical Science
https://jkms.org/DOIx.php?id=10.3346/jkms.2013.28.9.1293
Podoplanin, α-Smooth Muscle Actin or S100A4 Expressing Cancer-Associated Fibroblasts Are Associated with Different Prognosis in Colorectal ...
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51 Combination of Wnt/β-Catenin Targets S100A4 and DKK1 ...
https://www.epo-berlin.com/assets/documents/Publikationen/Publikat2022/cancers-14-00037.pdf
S100A4 with Wnt pathway antagonist Dickkopf-1 (DKK1). ... Keywords: S100A4; DKK1; Wnt signaling; colorectal cancer; patient survival.
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52 S100A4-induced cell motility and metastasis is restricted by the Wnt ...
https://baam.library.gwu.edu/discovery/fulldisplay?docid=cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3172260&context=PC&vid=01WRLC_GWA:live&lang=en&search_scope=DN_and_CI&adaptor=Primo%20Central&query=creator%2Cexact%2C%20Lu%2C%20Yiling%20%2CAND&facet=citing%2Cexact%2Ccdi_FETCH-LOGICAL-1974t-f9901c683f5b5eda060385782e7f9c5a19dd5a43c9e6172d5d87764c0baf366c3&offset=0
The calcium-binding protein S100A4 is a central mediator of metastasis formation in colon cancer. S100A4 is a target gene of the Wnt/β-catenin pathway, ...
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53 S100A4 alters metabolism and promotes invasion of lung ...
https://www.jbc.org/article/S0021-9258(20)36823-X/fulltext
Based on previous studies that niclosamide targets S100A4 signaling to inhibit proliferation and invasion of colon and lung cancer cells (.
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54 Podoplanin, α-Smooth Muscle Actin or S100A4 Expressing ...
https://synapse.koreamed.org/articles/1022056
Podoplanin, α-Smooth Muscle Actin or S100A4 Expressing Cancer-Associated Fibroblasts Are Associated with Different Prognosis in Colorectal ...
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55 Clinical relevance of circulating MACC1 and S100A4 transcripts in ...
https://www.annalsofoncology.org/article/S0923-7534(19)49426-X/fulltext
Background: Metastasis-associated in colon cancer 1 (MACC1) and S100 calcium binding protein A4 (S100A4) promote metastasis. Their overexpression in the ...
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56 Overexpression of S100A4 is closely associated with progression of ...
https://xueshu.baidu.com/usercenter/paper/show?paperid=8184236c78169a97e4ddc911cedb4d91
摘要:. AIM: To investigate whether S100A4 played an important role in the development or progression of colorectal cancer.METHODS: A total of 124 ...
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57 Clinical relevance of circulating MACC1 and S100A4 transcripts in ...
https://oncologypro.esmo.org/meeting-resources/esmo-2018-congress/clinical-relevance-of-circulating-macc1-and-s100a4-transcripts-in-serum-of-ovarian-cancer-patients
Metastasis-associated in colon cancer 1 (MACC1) and S100 calcium binding protein A4 (S100A4) promote metastasis. Their overexpression in the tumor was ...
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58 S100A4 May Be a Good Prognostic Marker and a ... - Bezmialem
https://openaccess.bezmialem.edu.tr/handle/20.500.12645/23702
Globally, the colorectal cancers rank the third in terms of cancer incidence and rank the fourth in cancer-associated deaths. S100A4, an important member of ...
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59 anti-S100A4 antibody | Rabbit S100A4 Polyclonal Antibody ...
https://www.mybiosource.com/polyclonal-human-mouse-rat-antibody/s100a4/2527785
Immunohistochemistry of paraffin-embedded Human colon cancer tissue using S100A4 Polyclonal Antibody at dilution 1:80 anti-S100A4 antibody ...
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60 Colon Cancer: New Insights for the Healthcare Professional: ...
https://books.google.com/books?id=uGKFTiWgQ_0C&pg=PA283&lpg=PA283&dq=s100a4+colon+cancer&source=bl&ots=pNJghuAL27&sig=ACfU3U2WSi6X1BW6XISaGnASgfSO1FWong&hl=en&sa=X&ved=2ahUKEwi8wYuXis_7AhV0q5UCHU-DDlYQ6AF6BQiEAhAD
... XII as a marker of myofibroblastic differentiation during colorectal cancer metastasis. ... by NewsRx correspondents, research stated, “S100A4 protein, ...
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61 Journal of the National Cancer Institute: JNCI.
https://books.google.com/books?id=2BVYr4uSQOYC&pg=PA1035&lpg=PA1035&dq=s100a4+colon+cancer&source=bl&ots=vmUnm5OsNv&sig=ACfU3U02IFzVCr2wcilTjo8DUyAdCMGB3w&hl=en&sa=X&ved=2ahUKEwi8wYuXis_7AhV0q5UCHU-DDlYQ6AF6BQiGAhAD
S100A4 expreszation of frizzled - 1 and proteasomal degradation of CTNNB1 sion in tumors from colon cancer patients was shown to be prog( 34 ) .
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62 Colon Cancer: New Insights for the Healthcare Professional: ...
https://books.google.com/books?id=Xr9HbNCWh5QC&pg=PA161&lpg=PA161&dq=s100a4+colon+cancer&source=bl&ots=bbNwAwNSc3&sig=ACfU3U1h0uI_ySqeLfE0RjLBvk_suyvZow&hl=en&sa=X&ved=2ahUKEwi8wYuXis_7AhV0q5UCHU-DDlYQ6AF6BQiJAhAD
Approximately 15% of colorectal cancers display MSI due to a germline mutation in one ... colon cancer cells New research, “S100A4-induced cell motility and ...
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63 Colon Cancer Expanded Version | ASCRS
https://fascrs.org/patients/diseases-and-conditions/a-z/colon-cancer-expanded-version
Many colon cancers cause no symptoms at all and are detected during routine screening examinations. The most common symptom of colorectal cancer is a change in ...
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64 Significance of the metastasis-promoting protein S100A4 in ...
https://www.duo.uio.no/handle/10852/34222
Colorectal cancer (CRC) is a common type of cancer, and at present the TNM staging system is the only tool in routine clinical use for predicting patient ...
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65 The Metastasis-Associated Gene S100A4 Is a Novel Target of β ...
https://ur.booksc.eu/book/20698142/3c2e92
The Metastasis-Associated Gene S100A4 Is a Novel Target of β-catenin/T-cell Factor Signaling in Colon Cancer | Ulrike Stein; Franziska Arlt; ...
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66 Most metastatic colorectal cancers have spread before ...
https://med.stanford.edu/news/all-news/2019/06/most-metastatic-colorectal-cancers-have-spread-before-diagnosis.html
Colorectal cancers often spread before the initial tumor is detected, ... Christina Curtis and her colleagues found that colon cancer tumors ...
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67 Colorectal cancer - Colon - A.D.A.M. Inc.
http://uhealth.adam.com/content.aspx?productid=117&isarticlelink=false&pid=1&gid=000262
Almost all colon cancers start in the lining of the colon and rectum. When doctors talk about colorectal cancer, this is usually what they are talking about.
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68 Colorectal Cancer - Learning oncology
https://www.learnoncology.ca/modules/colorectal-cancer
Understand that colorectal cancer treatment is different depending on whether the tumour is primarily located in the colon or rectum.
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69 Overview: A 65-Year-Old Man with Metastatic Colorectal Cancer
https://www.targetedonc.com/view/overview-a-65-year-old-man-with-metastatic-colorectal-cancer
Tanios Bekaii-Saab, MD, FACP, provides an overview of a case involving a 65-year-old man diagnosed with stage 4 metastatic colorectal cancer.
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70 Colorectal Cancer: The Good, the Bad, and the Revolutionary
https://norgenbiotek.com/blog/colorectal-cancer-good-bad-and-revolutionary
biomarkers Colorectal Cancer Customer Stories Detection microRNA RNA ... If experts say that colorectal cancer (CRC) is one of the most ...
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71 UVM researchers work to find better ways to treat colorectal ...
https://www.wcax.com/2022/02/18/uvm-researchers-work-find-better-ways-treat-colorectal-cancer-patients/
New UVM research aims to help colorectal cancer patients balance treatment with their quality of life. Our Cat Viglienzoni learned how.
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72 Colon Cancer: New Insights for the Healthcare Professional: ...
https://books.google.com/books?id=mTLDWHnPF1wC&pg=PA605&lpg=PA605&dq=s100a4+colon+cancer&source=bl&ots=OEcrRSvlMD&sig=ACfU3U1nuHLptY_RvxMY8kG8K4m54Z_N_A&hl=en&sa=X&ved=2ahUKEwi8wYuXis_7AhV0q5UCHU-DDlYQ6AF6BQiAAhAD
... and clinical outcome in colorectal cancer after surgery New investigation results, 'Expression status ofS100A14 and S100A4 correlates with metastatic ...
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