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1 Management of Chemotherapy Extravasations - U.S. Pharmacist
https://www.uspharmacist.com/article/management-of-chemotherapy-extravasations
In one case, a 10-mg daunorubicin extravasation in a 42-year-old man was treated with sodium bicarbonate, dexamethasone (4 mg), ice packs, ...
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2 Treatment of extravasation of both doxorubicin and ... - PubMed
https://pubmed.ncbi.nlm.nih.gov/8833558/
Doxorubicin is one of the most widely used drugs and hence has the highest potential and risk for extravasation, and, therefore, dexrazoxane should be made ...
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3 Management of chemotherapy extravasation: ESMO–EONS ...
https://www.annalsofoncology.org/article/S0923-7534(19)37675-6/fulltext
One single systemic dose of dexrazoxane immediately after s.c. administration of doxorubicin, daunorubicin, or idarubicin reduced the tissue lesions (expressed ...
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4 Extravasation injury from chemotherapy and other ... - UpToDate
https://www.uptodate.com/contents/extravasation-injury-from-chemotherapy-and-other-non-antineoplastic-vesicants
Extravasation refers to the escape of a drug into the extravascular space, either by leakage from a vessel or by direct infiltration.
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5 3.3.2 Antidotes and Treatments for Extravasation - POGO
https://www.pogo.ca/satellite-manual/3-0-chemotherapy-administration/3-3-extravasation-management/3-3-2-antidotes-and-treatments-for-extravasation/
3.3.2 Antidotes and Treatments for Extravasation ... Remove the IV/port needle. Apply cold pack initially for 30–60 minutes. Remove 15 minutes ...
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6 What are current recommendations for treatment of drug ...
https://dig.pharmacy.uic.edu/faqs/2021-2/february-2021-faqs/what-are-current-recommendations-for-treatment-of-drug-extravasation/
Warm compresses are preferred for extravasation of specific drugs including vinca alkaloids, etoposide, vasopressors, and oxaliplatin to ...
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7 Chemotherapy Extravasation | PSNet
https://psnet.ahrq.gov/web-mm/chemotherapy-extravasation
Extravasation of the medication into the skin is one of the most dreaded complications that can occur during chemotherapy administration (1), as patients can ...
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8 157-Extravasation management - eviQ
https://www.eviq.org.au/clinical-resources/extravasation/157-extravasation-management
Neither clinical nor experimental studies have shown an antidote to doxorubicin extravasation, which is best prevented by careful technique. If extravasation is ...
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9 management-extravasation-of-a-systemic-anti-cancer-therapy ...
https://www.england.nhs.uk/midlands/wp-content/uploads/sites/46/2019/05/management-extravasation-of-a-systemic-anti-cancer-therapy-including-cytotoxic-agents.pdf
Savene is indicated for the treatment of extravasation by one of the following anthracycline agents: Doxorubicin, Epirubicin, Idarubicin and ...
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10 Extravasation Of Chemotherapeutic Agents
https://www.gairgair.com/extravasation-of-chemotherapeutic-agents.html
Since no specific antidote has been developed, the recommended treatment of Doxorubicin extravasation is early excission of all infiltrated tissue. Dahlstrom, ...
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11 Extravasation Injury as a Result of VAD Chemotherapy
https://journals.lww.com/jwocnonline/fulltext/2007/05000/extravasation_injury_as_a_result_of_vad.11.aspx
Vincristine and doxorubicin are potent vesicant drugs. Therefore, early recognition of possible extravasations plays a crucial role in minimizing damage ...
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12 Extravasation of Liposomal Doxorubicin Induces Irritant ...
https://ar.iiarjournals.org/content/32/4/1481
The encapsulation of doxorubicin within a macromolecular vector, the liposome, significantly modifies its distribution volume, diminishing its diffusion and, ...
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13 Dexrazoxane treatment of doxorubicin ... - AVMA Journals
https://avmajournals.avma.org/downloadpdf/journals/javma/240/3/javma.240.3.304.pdf?pdfJsInlineViewToken=1931384022&inlineView=true
For the first chemotherapy treatment, the dog was prescribed doxorubicin (30 mg/m2 [50 mg total]) diluted in 425 mL of saline (0.9% NaCl) solution. A catheter ...
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14 Extravasation of systemic hemato-oncological therapies
https://www.sciencedirect.com/science/article/pii/S0923753419618363
The repetitive nature of this process impairs healing and may result in progressive and chronic tissue injury. With prolonged retention of doxorubicin in skin ...
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15 Chemotherapy Extravasation | ESMO
https://www.esmo.org/guidelines/guidelines-by-topic/supportive-and-palliative-care/chemotherapy-extravasation
Published in 2012 – Ann Oncol 2012; 23 (Suppl 7): vii167-vii173. ... Extravasation is the process by which any liquid (fluid or drug) accidentally leaks into the ...
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16 Tissue distribution of epirubicin after severe extravasation in ...
https://link.springer.com/article/10.1007/s00280-021-04280-8
All patients were treated with surgical débridement followed by either ... Doxorubicin tissue distribution after extensive extravasation ...
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17 Totect™: A New Agent for Treating Anthracycline Extravasation
https://www.ons.org/system/files/journal-article-pdfs/2Q107PK52373686N.pdf
Only 1 of 54 patients with doxorubicin or epirubicin biopsy-confirmed extravasations treated with Totect developed tissue necrosis. Because nurses are on the ...
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18 Treatment of Extravasation of both ... - SAGE Journals
https://journals.sagepub.com/doi/10.1177/106002809603000306
Topical dimethyl sulfoxide four times daily for 14 days plus subcutaneous chondroitinsulfatase in one or two applications effectively treated an extravasation ...
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19 Case report Extravasation of doxorubicin - Termedia
https://www.termedia.pl/Case-report-Extravasation-of-doxorubicin-a-dreaded-complication-of-therapy,77,22239,1,1.html
The application was immediately stopped and about 8 ml of extravasation was aspirated. The patient was hospitalized and local treatment (cooling) ...
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20 Vesicant/Irritant and Extravasation Management Guidelines
https://specialove.org/wp-content/uploads/2019/08/PRO_Extravasation_and_Flare_Management_App_B.pdf
liposomal daunorubicin extravasation management. 2,3,11-14 ... If extravasation is noted within 6 hours of doxorubicin infusion: administer dexrazoxane (see.
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21 Vesicant & irritant chemotherapy - A Hematology Oncology Wiki
https://hemonc.org/wiki/Vesicant_%26_irritant_chemotherapy
Chemotherapy vesicant & irritant properties and suggested management for extravasation · 15 to 20 minutes at a time for at least four times per day for 24-48 ...
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22 Clinical Guidelines (Nursing) : Extravasation injury management
https://www.rch.org.au/rchcpg/hospital_clinical_guideline_index/Extravasation_injury_management/
Acute management · Evidence suggests hyaluronidase irrigation for parenteral nutrition and calcium chloride extravasation is beneficial. · Hylauronidase should be ...
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23 A Focus on the Treatment of Anthracycline Extravasation and ...
https://touchoncology.com/supportive-cancer-care/journal-articles/a-focus-on-the-treatment-of-anthracycline-extravasation-and-tissue-protection/
Millions of patients have received treatment with doxorubicin, epirubicin, daunorubicin, and several newer analogs. Regrettably, a small ...
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24 Accidental Extravasation of Chemotherapy - The ASCO Post
https://ascopost.com/issues/april-15-2014/accidental-extravasation-of-chemotherapy/
Depending on the type of the extravasated compound, the volume, and the area of extravasation, treatment options include cooling (or heating in ...
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25 Extravasation - Squarespace
https://static1.squarespace.com/static/5d8750e6111bdc1bcfc37cc3/t/5f5f6daa9e32a319f568960d/1600089517796/Extravasation+Protocol+%28The+Pet+Oncologist%29.pdf
EXTRAVASATION OF ANY CHEMOTHERAPY DRUG (PARTICULARLY. DOXORUBICIN) IS TREATED AS A MEDICAL EMERGENCY, AND IMMEDIATE. ACTION MUST BE TAKEN. Clinical findings ...
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26 Extravasation Reactions - Wiley Online Library
https://onlinelibrary.wiley.com/doi/pdf/10.1002/9781118590638.ch28
International guidelines for prevention and treatment are ... Figure 28.2 The result of an untreated extravasation of doxorubicin into the.
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27 Vesicant Extravasation From an Implanted Venous Access Port
https://www.cancernetwork.com/view/vesicant-extravasation-implanted-venous-access-port
[8] High concentrations of doxorubicin are usually administered via syringe through the sidearm of a running intravenous infusion (IV) or as a ...
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28 Management of Anthracycline Extravasation Injuries
https://digitalcommons.butler.edu/cgi/viewcontent.cgi?referer=&httpsredir=1&article=1213&context=cophs_papers
1 Those particularly harmful when extravasated include the anthracyclines (doxorubicin, daunorubicin, epirubicin, idarubicin), and treatment of such a.
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29 Extravasation of Adriamycin and other vasosclerotics ...
https://www.dvm360.com/view/extravasation-adriamycin-and-other-vasosclerotics-proceedings
When treating oncology patients, technicians realize more stress and job pressure with dealing with chemotherapy drugs that are vasosclerotics ...
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30 Cancer chemotherapy agent-induced perivenous extravasation
https://pmj.bmj.com/content/postgradmedj/63/735/5.full.pdf
doxorubicin-DNA complexes. However, the onset of. Table II Suggested protocol for immediate management of vesicant extravasation. Aspirate residual drug.
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31 Pharmacological management of anticancer agent extravasation
https://www.ions.org.il/ImagesFck/Siud/file/%D7%A0%D7%94%D7%9C%D7%99%D7%9D%20%D7%94%D7%A0%D7%97%D7%99%D7%95%D7%AA%20%D7%9E%D7%A7%D7%A6%D7%95%D7%A2%D7%99%D7%95%D7%AA/%D7%90%D7%A7%D7%A1%D7%98%D7%A8%D7%95%D7%95%D7%96%D7%A6%D7%99%D7%94%20%D7%A9%D7%9C%20%D7%9B%D7%99%D7%9E%D7%95%D7%AA%D7%A8%D7%A4%D7%99%D7%94%202018.pdf
the prevention of doxorubicin cardiomyopathy and the treatment of anthracycline extravasation. Anthracyclines are cytotoxic agents, which exert their.
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32 (PDF) Extravasation of doxorubicin – a dreaded complication ...
https://www.researchgate.net/publication/271514891_Extravasation_of_doxorubicin_-_a_dreaded_complication_of_therapy
Nowadays there are new approaches to the treat ment of doxorubicin extravasation, such as use of specific antidote dexra zoxane.
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33 EXTRAVASATION PROCEDURE - Tayside Area Formulary
https://www.nhstaysideadtc.scot.nhs.uk/approved/policy/EXTRAV.PDF
Other Items Required For The Treatment Of Extravasation ... The administration of daunorubicin or doxorubicin (and possibly other anthracyclines).
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34 NEW YORK MEDICAL MALPRACTICE
https://www.newyorkpersonalinjuryattorneysblog.com/medical_malpractice_1/
Since no specific antidote has been developed, the recommended treatment of Doxorubicin extravasation is early excission of all infiltrated ...
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35 Extravasation Management - YouTube
https://www.youtube.com/watch?v=tNVUf_WcRZ8
Kathryn the Educator
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36 Management of extensive doxorubicin hydrochloride ...
https://www.jhandsurg.org/article/S0363-5023(83)80048-3/abstract
The complications and morbidity secondary to doxorubicin hydrochloride extravasation are often more disabling than the patient's primary disease. The degree of ...
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37 Infiltration and Extravasation - Lynn Hadaway Associates
https://hadawayassociates.com/uploads/3/5/4/4/35447364/infiltration_and_extravasation__update_on.10_copy.pdf
27 In a 1994 report on 40 patients with suspected extravasations of vinca alka- loids or doxorubicin, conservative treatment with 20 to. 90 mL of saline ...
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38 Management of extravasation of antineoplastic agents
https://journals.viamedica.pl/oncology_in_clinical_practice/article/download/OCP.2018.0006/43309
Systemic treatment of cancer patients is very often ... Clinical symptoms of extravasation . ... extravasation (e.g. hypersensitivity to doxorubicin). The.
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39 Extravasation Policy for All Drugs, Chemotherapy & Non ...
https://therapeuticportal.nhsh.scot/media/2596/extravasation-docebver-4jan2014.pdf
Section 1 - Immediate First Aid Management of Extravasation ... you are unsure which drug extravasated, you would treat it as a Doxorubicin.
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40 Determination of Extravasation Effects of Nal-Iri and ... - Frontiers
https://www.frontiersin.org/articles/10.3389/fphar.2022.875695/full
Background: Extravasation during chemotherapy administration can lead to dangerous adverse effects ranging from pain to tissue necrosis.
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41 Antineoplastic Extravasation Prevention, Management
https://www.pharmacytimes.com/view/antineoplastic-extravasation-prevention-management
Antineoplastic Extravasation Prevention, Management · Disconnect tubing while leaving the cannula in place · Without applying pressure, carefully ...
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42 Vesicant extravasation due to doxorubicin administration in a ...
https://www.izmironcologist.com/articles/g/G12.pdf
Chemotherapy extravasation, doxorubicin, treatment. Introduction. The extravasation of cancer chemotherapeutic agents is.
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43 Managing Extravasation During Chemotherapy Administration
https://www.oncologynurseadvisor.com/home/hot-topics/side-effect-management/cancer-chemotherapy-administration-manage-extravasation-risk-treatment/
Chemotherapy extravasation occurs when a vesicant medication leaks out of a vein into the surrounding soft tissues during an intravenous ...
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44 Countering Doxorubicin Extravasation - Clinician's Brief
https://www.cliniciansbrief.com/article/countering-doxorubicin-extravasation
The dogs were treated with dexrazoxane, the only drug currently approved for anthracycline extravasation in humans. Administration occurred within 2 hours of ...
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45 Guidelines for the Management of Extravasation
https://www.northerncanceralliance.nhs.uk/wp-content/uploads/2018/11/NECN-Guidelines-for-Management-of-Extravasation-v5.5-Nov-2016.pdf
NECN Guidelines for Management of Extravasation v5.5 Nov 2016 ... Liposomal-Doxorubicin. Epirubicin. Idarubicin. Mitomycin. Mitoxantrone.
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46 Dexrazoxane for anthracycline extravasation and GM-CSF for ...
https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(04)01470-6/fulltext
reported that dexrazoxane prevented complications in two patients with accidental extravasation of doxorubicin and epirubicin. A further case of ...
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47 Extravasation - MD Anderson Cancer Center
https://www.mdanderson.org/content/dam/mdanderson/documents/for-physicians/algorithms/clinical-management/clin-management-extravasation-web-algorithm.pdf
APPENDIX A: Extravasation Management of Vesicants… ... APPENDIX C: Signs and Symptoms of Vesicant Extravasation… ... danorubicin, doxorubicin,.
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48 An Apparently Effective Countermeasure for Doxorubicin ...
https://jamanetwork.com/journals/jama/fullarticle/360027
To the Editor.—Doxorubicin hydrochloride (Adriamycin) extravasation inevitably leads to local tissue damage. The development of tissue ulceration depends on ...
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49 center for drug evaluation and research - Accessdata.fda.gov
https://www.accessdata.fda.gov/drugsatfda_docs/nda/2007/022025s000_MedR.pdf
Drug Type: Approved agent for cardioprotection from doxorubicin ... treatment of anthracycline chemotherapy extravasation. Dexrazoxane is.
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50 Recognising and reducing the risk of chemotherapy ...
https://archive.cancerworld.net/wp-content/uploads/2016/12/7823_pagina_47_52_eGranround.pdf
patient, greatly heighten their fears of undergoing future treatment cycles, and ... PROGRESSION AND TREATMENT OF EXTRAVASATION: DOXORUBICIN.
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51 Guidelines for Managing Anthracycline Extravasation
https://www.theoncologynurse.com/issue-archive/2011-issues/march-april-vol-4-no-2/3055-ton-3055
If there are symptoms or other signs of anthracycline extravasation (such as fluid leaking from the injection site or problems with the rate of infusion), ...
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52 Extravasation of doxorubicin - Semantic Scholar
https://pdfs.semanticscholar.org/9c1e/23fc28b1cc4f76b1c263dbcbee4d2ec599db.pdf
The cost of a therapeutic dose of dexrazoxane is still the most nega tive aspect of the treatment. Key words: doxorubicin, extravasation,.
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53 Dexrazoxane for the treatment of chemotherapy-related side ...
https://www.dovepress.com/dexrazoxane-for-the-treatment-of-chemotherapy-related-side-effects-peer-reviewed-fulltext-article-CMAR
In cancer treatment, extravasation of the widely used anthracyclines such as doxorubicin, daunorubicin, and epirubicin may lead to severe, ...
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54 Extravasation: Symptoms, Treatment, and Prevention
https://www.verywellhealth.com/what-is-extravasation-2252331
Extravasation is a skin reaction that happens when medications, including chemotherapy, leak outside of the vein. Learn about causes and ...
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55 Successful management of doxorubicin overdose and ...
https://europepmc.org/article/pmc/pmc6135299
Doxorubicin is a potent vesicant, causing severe tissue ulceration and necrosis. Dexrazoxane is the most effective treatment for anthracycline extravasation (16 ...
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56 CATASTROPHIC COMPLICATIONS OF CHEMOTHERAPY ...
https://journal.chestnet.org/article/S0012-3692(21)02175-9/fulltext
INTRODUCTION: Chemotherapy is the mainstay of cancer treatment. ... As vesicants, doxorubicin, and vincristine extravasation is known to ...
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57 Management of Cytotoxic Extravasation - Abstract
https://www.karger.com/Article/Abstract/348524
Extravasation must be diagnosed as soon as possible, and specific therapy including antidotes dependent on the extravasated drug should be ...
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58 Infiltration or Extravasation of Oxaliplatin
https://www.oncology.tv/SymptomManagement/InfiltrationorExtravasationofOxaliplatin.aspx
Examples are alkylating agents (carboplatin, ifosfamide, oxaliplatin) and liposomal doxorubicin.1-3. Oxaliplatin, an agent commonly used to treat CRC, ...
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59 Chemotherapy: extravasation - Vetstream
https://www.vetlexicon.com/treat/canis/freeform/chemotherapy-extravasation
Venable R O, Saba C F, Endicott M M et al (2012) Dexrazoxane treatment of doxorubicin extravasation injury in four dogs. JAVMA 240 (3), 304-307 PubMed.
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60 Management of extravasation policy - Manchester Cancer
https://manchestercancer.files.wordpress.com/2014/09/extravasation_sept20131.pdf
regimen, then treat as for doxorubicin. See appendix 1 for summary flow chart. 7.1 Procedure for the IMMEDIATE management of peripheral extravasation.
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61 doxorubicin.pdf - Cancer Care Ontario
https://www.cancercareontario.ca/en/system/files_force/doxorubicin.pdf?download=1
Extravasation Potential: Vesicant. Incidences below are based on various sources. Incidences reported from the doxorubicin treatment.
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62 EXTRAVASATION OF CHEMOTHERAPY AGENTS ...
https://www.rqhealth.ca/service-lines/clinical-quality-professional-practice/files/E.9.pdf
Treat and minimize complications of tissue damage associated with extravasation of vesicant medications. NURSING ALERT:.
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63 Intravenous Extravasation of Cytotoxic Drugs - Oncolex
http://oncolex.org/Stomach-cancer/Procedures/TREATMENT/ComplicationTreatment/Intravenous-extravasation-of-cytotoxic-drugs?chapter=4
Dexrazoxan is an EDTA analong used to treat extravasation of anthracycline (doxorubicin, daunorubicin, epirubicin, idarubicin). The mechanism of action is ...
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64 Doxorubicin extravasation from a port-a-cath into pleural ...
https://www.jiaps.com/article.asp?issn=0971-9261;year=2022;volume=27;issue=5;spage=648;epage=651;aulast=Tom
Except in a few cases, all the patients with reported extravasation had good outcomes both in terms of the management of the disease and the ...
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65 Effects of Fat Injection in Vesicant (Doxorubicin) Induced Skin ...
https://www.tandfonline.com/doi/abs/10.1080/08941939.2021.1966142
The most common drugs associated with extravasation injury include ... are next steps in treatment of the condition including antidotes, volume dilution, ...
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66 severe skin necrosis after rituximab-CHoP therapy - NJM
https://njmonline.nl/getpdf.php?id=730
The cancer chemotherapeutic drug doxorubicin is known for its severe acute local complications after extravasation.1. Rituximab is a monoclonal antibody ...
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67 Extravasation LIT REVIEW for publication.pdf
https://openaccess.city.ac.uk/13830/3/Extravasation%20LIT%20REVIEW%20for%20publication.pdf
extravasation management dating from the introduction of cytotoxic drugs as a ... which is used in clinical practice (eMC Doxorubicin Rapid Dissolution, ...
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68 Vesicant and Irritant Agents (Oncology) - CE - Elsevier
https://www.elsevier.com/__data/assets/pdf_file/0020/1002287/Antineoplastic-Drug-Administration-Vesicant-and-Irritant-Agents-Skill-Oncology-COVID-19-Toolkit_140420.pdf
Chemotherapy extravasation management: 21-year experience. Annals of Plastic Surgery, 79[5], ... Liposomal doxorubicin. • Mitoxantrone.
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69 Skin Cancer Occurring 10 Years after the Extravasation of ...
https://www.nejm.org/doi/full/10.1056/nejm199503163321117
Adjuvant chemotherapy consisting of doxorubicin (50 mg per square meter of body-surface area on day 1), mitomycin (10 mg per square meter on day ...
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70 Guidelines on treatment of extravasation with cytotoxic drugs
https://thamesvalleycanceralliance.nhs.uk/wp-content/uploads/2021/05/Extravasation-TVSCN-Guidelines-version-5-April-2018.pdf
Guidelines on treatment of extravasation with cytotoxic drugs ... ABVD: administer doxorubicin, vincristine, bleomycin and dacarbazine. Whilst.
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71 Doxorubicin 2 mg/ml Concentrate for Solution for Infusion
https://www.medicines.org.uk/emc/product/6112/smpc
Doxorubicin may be used by intravesical instillation for the treatment of ... If extravasation occurs, the infusion or injection has to be stopped at once; ...
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72 Chemotherapy Extravasation: Symptoms, Causes, Prevention ...
https://www.healthline.com/health/cancer/chemotherapy-extravasation
Chemotherapy extravasation happens when the liquid medication from chemotherapy accidentally leaks from your catheter or your veins into the ...
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73 Extravasation: Did Everything Right and It Still Goes Wrong!
https://ons.confex.com/ons/2017/mediafile/ExtendedAbstract/Session1097/Extravasation.pdf
Extravasation Treatment. Antineoplastic Agent. Antidote. Local Measures. Anthracyclines (doxorubicin, daunorubicin, epirubicin, idarubicin).
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74 Extravasation: Definition, symptoms, and treatment
https://www.medicalnewstoday.com/articles/extravasation
It is important that the person receiving the medication or their medical team notice the signs and symptoms of extravasation early to prevent ...
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75 Dexrazoxane treatment of doxorubicin extravasation injury in ...
https://agris.fao.org/agris-search/search.do?recordID=US201800250015
Dexrazoxane was administered within 2 hours after known extravasation in 3 dogs and 48 hours after suspected extravasation in 1 dog. Additional medical ...
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76 Highlights of Prescribing Information - Pfizer
https://labeling.pfizer.com/showlabeling.aspx?id=530
(5.2); Extravasation and Tissue Necrosis: Extravasation of doxorubicin ... as a component of multiagent adjuvant chemotherapy for treatment of women with ...
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77 Closing the Knowledge Gap On Extravasation
https://www.pharmacypracticenews.com/Clinical/Article/04-22/Closing-the-Knowledge-Gap-On-Extravasation/66553
A thoracic surgeon must assess drainage and management · Dexrazoxane is recommended, if locally approved, if anthracyclines are extravasated ...
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78 Knowledge is power when treating extravasation reactions
https://www.healio.com/news/hematology-oncology/20120325/knowledge-is-power-when-treating-extravasation-reactions
This increase in circulation would facilitate drug removal. Warm compresses are only recommended in the extravasation of the vinca alkaloids and ...
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79 DOXORUBICIN Boxed Warning (doxorubicin hydrochloride)
https://www.pfizermedicalinformation.com/en-us/doxorubicin/boxed-warning
Extravasation and Tissue Necrosis: Extravasation of doxorubicin hydrochloride can result in severe local tissue injury and necrosis requiring wide excision of ...
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80 Home Care Services - University of Michigan
https://homecare.med.umich.edu/Document/View/1388
TITLE: Management of Chemotherapy Extravasation. DEFINITIONS: Cytotoxic (Antineoplastic) Drugs: Drugs with a mechanism of action that focuses on killing a cell,.
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81 Canine Doxorubicin Extravasation Treated with Dexrazoxane.
https://www.jstage.jst.go.jp/article/jvcs/5/2/5_2014-002/_pdf/-char/ja
Doxorubicin is a cytotoxic drug widely used in the treatment of malignant tumors such as canine multicentric lymphoma. [9, 13]. Through extravasation ...
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82 Recent advances in anthracycline extravasation treatment
https://hospitalpharmacyeurope.com/news/editors-pick/recent-advances-in-anthracycline-extravasation-treatment/
Anthracycline chemotherapy agents (eg, daunorubicin, doxorubicin, epirubicin and idarubicin) have been used to treat various types of cancer ...
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83 Basic fibroblast growth factor in retardation of doxorubicin ...
https://www.gynecologiconcology-online.net/article/0090-8258(92)90035-H/fulltext
Extravasation of chemotherapeutic agents such as doxorubicin results in significant morbidity and remains a serious clinical problem.
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84 BC Cancer Extravasation Hazard Table
http://www.bccancer.bc.ca/drug-database-site/Documents/Extravasation%20Hazard%20Table.pdf
BC Cancer Extravasation Hazard Table (Systemic Therapy Policy ... DAUNOrubicin-cytarabine liposome ... DOXOrubicin pegylated liposomal.
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85 Comparison of granulocyte-colony, stimulating factor and ...
https://article.imrpress.com/journal/EJGO/21/6/pii/2000245/613-615.pdf
in the treatment of chemotherapy extravasation ulcers ... ulcers appeared on both lower arms related to doxorubicin extravasation despite all interventions.
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86 Extravasation injury from chemotherapy and other ... - medilib
https://www.medilib.ir/uptodate/show/2797
One-half were treated with hydrocortisone and dexamethasone alone, whereas the remainder also received sodium thiosulfate (2 percent solution ...
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87 Dexrazoxane use in the prevention of anthracycline ...
https://www.futuremedicine.com/doi/abs/10.2217/14796694.2.1.15
Accidental extravasation injury from the use of the anthracycline anticancer drugs doxorubicin, daunorubicin, epirubicin and idarubicin can be a serious ...
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88 Countering Doxorubicin Extravasation
https://files.brief.vet/migration/article/6346/cap_countering-doxorubicin-6346-article.pdf
with known or suspected doxorubicin extravasation are discussed. The dogs were treated with dexrazoxane, the only drug currently approved for anthracycline.
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89 Chemo-Extravasation - JaypeeDigital | eBook Reader
https://www.jaypeedigital.com/eReader/chapter/9789350258644/ch29
Dexrazoxane is the only treatment that has received European Commission authorization and USFDA approval for anthracycline extravasation treatment. The overall ...
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90 Management of Anthracycline Extravasation Injuries - CORE
https://core.ac.uk/download/pdf/62438622.pdf
CONCLUSIONS: The optimal treatment of anthracycline extravasation ... the treatment of doxorubicin extravasation, investigators found that DMSO plus vitamin ...
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91 Extravasation of Doxorubicin from Vascular Access Devices
https://www.liebertpub.com/doi/10.1089/sct.1990.6.103
In 20 patients (59%), spontaneous resolution without ulceration occurred in spite of occasional extravasation of large amounts of doxorubicin.
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92 Cutaneous Recall Phenomenon at the Site of Previous ...
https://academic.oup.com/jnci/article/99/2/177/2522182
Extravasation of doxorubicin is a severe complication. There is evidence suggesting that an increase in microvascular permeability due to ...
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93 Injection Site Reactions - Managing Side Effects - Chemocare
https://chemocare.com/chemotherapy/side-effects/injection-site-reactions.aspx
Treatments or Drugs for Injection Site Reactions: · Prevention of extravasation is the key to management of this problem. · If one of the above medications has ...
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94 Management of Extravasation Policy Document Ref:CP31 ...
https://gmcancerorguk.files.wordpress.com/2016/05/4346-policy-review-2016.pdf
5.2 APPROPRIATE TREATMENT FOLLOWING A SUSPECTED EXTRAVASATION. OF A VESICANT DRUG. ... Doxorubicin including liposomal. Epirubicin.
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95 Totect, Zinecard - dexrazoxane (Rx) - Medscape Reference
https://reference.medscape.com/drug/totect-zinecard-dexrazoxane-342250
Do not use with initiation of doxorubicin therapy ... Infuse IV over 1-2 hr once daily for 3 consecutive days; begin treatment within 6 hr of extravasation.
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96 Dealing With Chemotherapy Extravasations: A New Technique
https://meridian.allenpress.com/jaaha/article/42/4/321/176244/Dealing-With-Chemotherapy-Extravasations-A-New
It takes technical skill to administer these drugs, because they are caustic sclerotics. If doxorubicin is extravasated into the perivascular ...
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