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1 Treatment and Preventive Screening - Li-Fraumeni Syndrome ...
https://www.lfsassociation.org/what-is-lfs/treatment-preventive-screening/
At this time, there is no standard treatment or cure for LFS or a germline TP53 gene variant. With some exceptions, cancers in people with LFS are treated ...
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2 Li-Fraumeni Syndrome - NORD (National Organization for ...
https://rarediseases.org/rare-diseases/li-fraumeni-syndrome/
At this time, there is no standard treatment or cure for LFS or a germline TP53 gene variant. With some exceptions, cancers in people with LFS are treated the ...
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3 Successful treatment of a patient with Li–Fraumeni syndrome ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119081/
After two weeks of afatinib monotherapy at 40 mg a day orally, her fatigue, right-sided chest pain and dyspnea improved dramatically, and all her symptoms ...
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4 Li-Fraumeni Syndrome Treatment & Management
https://emedicine.medscape.com/article/987356-treatment
Physicians should discuss risk-reducing, prophylactic mastectomy with Li-Fraumeni syndrome women. It should be considered on a case-by-case ...
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5 Li-Fraumeni Syndrome | Cancer.Net
https://www.cancer.net/cancer-types/li-fraumeni-syndrome
When possible, people with a germline TP53 mutation should avoid or minimize exposure to diagnostic radiation, such as certain scans, and treatments that use ...
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6 Li-Fraumeni syndrome: MedlinePlus Genetics
https://medlineplus.gov/genetics/condition/li-fraumeni-syndrome/
Li-Fraumeni syndrome is a rare disorder that greatly increases the risk of developing several types of cancer, particularly in children and young adults.
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7 Li-Fraumeni syndrome - UpToDate
https://www.uptodate.com/contents/li-fraumeni-syndrome
Li-Fraumeni syndrome is an inherited autosomal dominant disorder that is manifested by a wide range of malignancies that appear at an ...
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8 About the Li-Fraumeni Syndrome and TP53 Center | Boston, MA
https://www.dana-farber.org/cancer-genetics-and-prevention/syndromes-genes-and-programs/li-fraumeni-syndrome-and-tp53-center/
Li-Fraumeni syndrome (LFS) is a hereditary condition which is often associated with a pathogenic or likely pathogenic variant (mutation) in the TP53 gene ...
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9 Li-Fraumeni Syndrome and Cancer | CTCA
https://www.cancercenter.com/risk-factors/li-fraumeni-syndrome
Li-Fraumeni syndrome (LFS) is a hereditary genetic condition that increases the predisposition to cancer. Families whose members have this syndrome face a ...
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10 Li-Fraumeni Syndrome | Children's Hospital of Philadelphia
https://www.chop.edu/conditions-diseases/li-fraumeni-syndrome
› conditions-diseases › li-fraume...
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11 Should Radiation Therapy be Avoided in Breast Cancer ...
https://www.redjournal.org/article/S0360-3016(19)33223-7/fulltext
Li-Fraumeni Syndrome (LFS) is a rare cancer-predisposing disease caused by germline mutations in a potent tumor suppressor gene calledTP53.
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12 Precision Medicine for Individuals with Li-Fraumeni Syndrome
https://dceg.cancer.gov/news-events/news/2022/lfs-precision-medicine
A rare, inherited disorder that is caused by mutations (changes) in the TP53 gene. Having Li-Fraumeni syndrome increases the risk of developing many types of ...
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13 What is Li-Fraumeni syndrome? | Nicklaus Children's Hospital
https://www.nicklauschildrens.org/conditions/li-fraumeni-syndrome
Children with Li-Fraumeni syndrome need to be under close observation due to the high cancer risk. If cancer occurs, it is often treated with ...
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14 Li-Fraumeni Syndrome - St. Jude Children's Research Hospital
https://www.stjude.org/disease/li-fraumeni.html
Are there other special health care needs for children with Li-Fraumeni syndrome? · Unexplained weight loss · Loss of appetite · Aches, pains, lumps or swellings ...
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15 Radiation therapy and secondary malignancy in Li‐Fraumeni ...
https://onlinelibrary.wiley.com/doi/full/10.1002/cam4.3427
The median dose among all patients was 50.4 Gy (range 15-66 Gy) and all but one patient was treated with standard fractionation with 1.8-2 Gy ...
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16 p53 therapy in a patient with Li-Fraumeni syndrome
https://aacrjournals.org/mct/article/6/5/1478/235084/p53-therapy-in-a-patient-with-Li-Fraumeni-syndrome
Hence, novel, nongenotoxic therapies for Li-Fraumeni syndrome tumors are clearly needed. Adenoviral p53 is a targeted molecular therapy that ...
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17 Li Fraumeni syndrome - Orphanet
https://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=524
Management of LFS-related cancers generally follows standard treatment protocols, with minimizing radiation when possible. Mastectomies are recommended over ...
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18 Guidelines for the Li–Fraumeni and heritable TP53 ... - Nature
https://www.nature.com/articles/s41431-020-0638-4
Heterozygous germline TP53 alterations were identified in 1990 in the Li–Fraumeni syndrome (LFS), described in 1969 by Frederick Li and Joseph ...
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19 Li–Fraumeni syndrome - Wikipedia
https://en.wikipedia.org/wiki/Li%E2%80%93Fraumeni_syndrome
› wiki › Li–Fraumeni_syndrome
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20 City of Hope to lead national research aimed at improving ...
https://www.cityofhope.org/news/weitzel-nih-grant-to-study-li-fraumeni-syndrome
Persons who inherit Li-Fraumeni syndrome (LFS) have an extremely ... Institutes of Health seeks to advance research and treatment for this ...
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21 Lung Cancer in Li-Fraumeni Syndrome - ASCO Journals
https://ascopubs.org/doi/full/10.1200/PO.20.00468
Li-Fraumeni syndrome (LFS) is a rare cancer predisposition syndrome characterized by germline pathogenic variants in the TP53 tumor suppressor ...
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22 Is there a treatment for Li-Fraumeni syndrome? - ThinkGenetic
https://www.thinkgenetic.com/diseases/li-fraumeni-syndrome-1/treatment
There is no treatment that can cure Li-Fraumeni syndrome. That being said, there are options available to reduce your risk of developing cancer.
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23 Unusual course of disease and genetic profile in Li-Fraumeni ...
https://hccpjournal.biomedcentral.com/articles/10.1186/s13053-021-00202-0
Somatic TP53 gene mutation frequently occurs in sporadic osteosarcoma. When arising germline, TP53 mutation leads to Li-Fraumeni syndrome and ...
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24 Clinical and Genetic Studies of Li-Fraumeni Syndrome
https://clinicaltrials.gov/ct2/show/NCT01443468
- Li-Fraumeni syndrome (LFS) is a genetic condition that increases the risk for some types of cancer. LFS may lead to cancer of the bone or connective tissue, ...
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25 Breast Cancer Patient with Li-Fraumeni Syndrome: A Case ...
https://www.karger.com/Article/FullText/505684
Germline mutations in TP53, a tumor suppressor gene, are involved in the development of Li-Fraumeni syndrome, a rare disorder that predisposes carriers to ...
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26 A Four-Year-Old Female With a Rare P53 Gene Mutation ...
https://www.cureus.com/articles/105510-a-four-year-old-female-with-a-rare-p53-gene-mutation-diagnosed-with-li-fraumeni-syndrome-and-concomitant-metastatic-rhabdomyosarcoma-a-case-report
Li-Fraumeni syndrome (LFS) is an uncommon genetic cancer syndrome characterized by autosomal dominant mutations of the TP53 tumor suppressor ...
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27 Li-Fraumeni Syndrome Screening - Adult
https://www.mdanderson.org/content/dam/mdanderson/documents/for-physicians/algorithms/screening/screening-li-fraumeni-web-algorithm.pdf
For women treated for breast cancer, screening of remaining breast tissue should continue. ○ Colonoscopy. ○ Esophagogastroduodenoscopy (EGD). CBC with ...
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28 Li-Fraumeni Syndrome: The Genetics and Treatment ...
https://www.sciencedirect.com/science/article/pii/S1055320708001038
Li-Fraumeni syndrome is an autosomal dominant disorder first reported by Drs Li and Fraumeni in 1969. Malkin was the first to describe a germline mutation ...
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29 Inhibiting the Priming for Cancer in Li-Fraumeni Syndrome
https://www.mdpi.com/2072-6694/14/7/1621
No treatments exist to reduce this cancer risk. This paper reviews the evidence for how cancers start in people with LFS and proposes that a series of commonly ...
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30 Conservative Therapy for Early-Stage Breast Cancer ... - JNCCN
https://jnccn.org/downloadpdf/journals/jnccn/10/8/article-p939.xml
Abstract. Li-Fraumeni syndrome (LFS) is one of the most penetrant forms of familial cancer susceptibility syndromes, characterized by early age.
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31 Upfront Radiotherapy May Benefit Medulloblastoma Patients ...
https://www.cancertherapyadvisor.com/home/news/conference-coverage/ispno-2022/medulloblastoma-li-fraumeni-syndrome-upfront-radiotherapy-benefit/
Upfront Radiotherapy May Benefit Medulloblastoma Patients With Li-Fraumeni Syndrome · Get Cancer Therapy Advisor in Your Inbox · Log in to Cancer ...
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32 Li-Fraumeni Syndrome Symptoms, Doctors, Treatments ...
https://www.medifind.com/conditions/li-fraumeni-syndrome/3026
Li-Fraumeni syndrome is a rare disorder that greatly increases the risk of developing several types of cancer, particularly in children and young adults. Save ...
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33 A to Z: Li-Fraumeni Syndrome
https://www.hopkinsallchildrens.org/Patients-Families/Health-Library/HealthDocNew/A-to-Z-Li-Fraumeni-Syndrome-(1)
There is currently no cure for Li-Fraumeni syndrome. Early diagnosis can help doctors be ready to treat any tumors or cancers that develop. The earlier ...
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34 Family Cancer Syndromes
https://www.cancer.org/healthy/cancer-causes/genetics/family-cancer-syndromes.html
People with Li-Fraumeni syndrome can develop more than one cancer in their lifetime. ... so doctors treating these patients might try to avoid giving them ...
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35 Li-Fraumeni Syndrome & Genetic Testing
https://www.mskcc.org/cancer-care/risk-assessment-screening/genetic-counseling-and-testing/hereditary-cancer-genes-and-hereditary-cancer-syndromes/li-fraumeni-syndrome
The cancers most closely associated with Li-Fraumeni syndrome are soft tissue sarcoma, osteosarcoma, premenopausal breast cancer, brain tumors, ...
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36 Full article: Breast cancer in patients with Li–Fraumeni syndrome
https://www.tandfonline.com/doi/full/10.2147/BCTT.S134241
Breast cancer among patients with LFS needs a multidisciplinary treatment approach. Surgical management follows the guidelines for the general ...
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37 Frequently Asked Questions about Li-Fraumeni Syndrome
https://healthcare.utah.edu/huntsmancancerinstitute/news/2022/06/frequently-asked-questions-about-li-fraumeni-syndrome.php
There is no cure for LFS. If you know you have LFS, certain cancer screenings are recommended that can help find cancer at an earlier stage, ...
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38 Hope in the shadow of Li-Fraumeni syndrome
https://answers.childrenshospital.org/hope-li-fraumeni-syndrome/
Jake was diagnosed with his first cancer — osteosarcoma — in 2007 when he was only 16 years old. Meanwhile, his mom was being treated for ...
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39 Breast Cancer after Radiation Therapy in a Patient with Li ...
https://jksronline.org/pdf/10.3348/jksr.2021.0045
Li-Fraumeni syndrome (LFS) is an inherited autosomal-dominant tumor-predisposition disor- der caused by germline mutations in the TP53 tumor suppressor gene ...
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40 289. Adenoviral-Mediated p53 Gene Therapy (Advexin) in a ...
https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(06)00601-0
Biopsy results and p53 expression data will be reviewed. This is the first case of malignancy in Li-Fraumeni syndrome treated with adenoviral-mediated p53 gene ...
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41 Breast Cancer Phenotype Associated With Li-Fraumeni ...
https://www.frontiersin.org/articles/10.3389/fonc.2022.836937/full
Li-Fraumeni syndrome (LFS; OMIM 151623) is an autosomal dominant condition that is associated with an increased risk of developing cancer. It is ...
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42 A to Z: Li-Fraumeni Syndrome (for Parents) - HackensackUMC
https://kidshealth.org/Hackensack/en/parents/az-li-fraumeni.html
There is currently no cure for Li-Fraumeni syndrome. Early diagnosis can help doctors be ready to treat any tumors or cancers that develop. The earlier ...
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43 Investigators Explore Metformin to Prevent Cancers in Li ...
https://www.onclive.com/view/investigators-explore-metformin-to-prevent-cancers-in-li-fraumeni-syndrome-carriers
Individuals with Li-Fraumeni Syndrome, a rare hereditary condition, are at increased risk for a wide spectrum of malignancies, ...
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44 Hematologic malignancies and Li–Fraumeni syndrome
http://molecularcasestudies.cshlp.org/content/5/1/a003210.full
Overall, although most patients with hematologic malignancy and LFS were able to obtain an initial response to induction therapy (either intensive cytarabine- ...
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45 Inhibiting the Priming for Cancer in Li-Fraumeni ... - MDPI
https://mdpi-res.com/d_attachment/cancers/cancers-14-01621/article_deploy/cancers-14-01621.pdf?version=1648020871
Simple Summary: Li-Fraumeni Syndrome (LFS) is a rare cancer ... Lessons learned from cancer prevention and treatment in people with LFS may ...
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46 Li-Fraumeni Syndrome - CancerIndex
http://www.cancerindex.org/Li_Fraumeni_Syndrome
Many members of Li-Fraumeni families have a germline mutation (an gene alteration you are born with) of the TP53 tumor suppressor gene. Compared ...
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47 Li-Fraumeni Syndrome Article - StatPearls
https://www.statpearls.com/ArticleLibrary/viewarticle/24243
Li-Fraumeni syndrome (LFS) occurs due to germ-line mutations in TP53. TP53 is a tumor suppressor gene, which is located on band 17p13.1, which ...
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48 analysis of an intensively treated Li–Fraumeni family
https://www.researchgate.net/publication/276850681_TP53_germline_mutation_may_affect_response_to_anticancer_treatments_analysis_of_an_intensively_treated_Li-Fraumeni_family
... Currently, there is no specific treatment for cancers related to Li-Fraumeni syndrome. However, it is advised to limit radiation therapy and ...
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49 749-TP53 (Li-Fraumeni) – risk management (adult) - eviQ
https://www.eviq.org.au/cancer-genetics/adult/risk-management/749-tp53-li-fraumeni-risk-management-adult
Li-Fraumeni syndrome (LFS) is caused by a germline pathogenic variant in the TP53 gene and is inherited in an autosomal dominant pattern.
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50 CAR T-cell therapy for a relapsed/refractory acute B-cell ...
https://jitc.bmj.com/content/8/1/e000364
Background Li-Fraumeni syndrome (LFS) is characterized as an autosomal dominant cancer predisposition disorder caused by germline TP53 gene mutations.
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51 Treatment for chondrosarcoma in Li Fraumeni syndrome
https://siope.eu/media/documents/treatment-for-chondrosarcoma-in-li-fraumeni-syndrome-whats-next.pdf
Treatment for chondrosarcoma in Li Fraumeni syndrome: what's next? Alberto Romano. I am a resident in Pediatrics at the Catholic University ...
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52 Analysis of the Li-Fraumeni Spectrum Based ... - JAMA Network
https://jamanetwork.com/journals/jamaoncology/fullarticle/2785678
Importance Li-Fraumeni syndrome is a cancer predisposition syndrome that is associated with a high, lifelong risk of a broad spectrum of cancers ...
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53 Effect of breastfeeding on the risk of breast cancer in Li ...
https://www.oncoamericas.com/effect-of-breastfeeding-on-the-risk-of-breast-cancer-in-li-fraumeni-syndrome/
Effect of breastfeeding on the risk of breast cancer in Li-Fraumeni syndrome · Related posts · Pembrolizumab in treatment of triple-negative breast cance ...
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54 Overview of TP53 gene mutations
https://www.facingourrisk.org/info/hereditary-cancer-and-genetic-testing/hereditary-cancer-genes-and-risk/genes-by-name/tp53/overview
TP53 mutations cause Li-Fraumeni syndrome. ... about how an inherited TP53 mutation may affect your options for cancer prevention, detection and treatment.
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55 a p53 gene-replacement therapy in Li-Fraumeni syndrome.
https://www.semanticscholar.org/paper/Potential-of-Advexin%3A-a-p53-gene-replacement-in-Nemunaitis-Nemunaitis/4431f22947f79e1fc945ddd72fdbd6d00ded88d6
Theoretically, correction of p53 function in cancer developing in patients with Li-Fraumeni syndrome through treatment with Advexin will ...
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56 Li-Fraumeni syndrome cancers, causes, symptoms, treatment ...
https://healthjade.com/li-fraumeni-syndrome/
Li-Fraumeni syndrome is a rare inherited disorder that greatly increases the risk of developing several types of cancer, particularly in children and young ...
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57 Pilot Study Assessing Tolerability and Metabolic Effects of ...
https://academic.oup.com/jncics/article/4/6/pkaa063/5873525
Li-Fraumeni syndrome (LFS) is a highly penetrant autosomal dominant cancer ... approved by the Food and Drug Administration to treat type 2 diabetes.
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58 Li-Fraumeni syndrome and the TP53 gene
https://www.sydneycancergenetics.com.au/genes-and-syndromes/li-fraumeni-syndrome-and-the-tp53-gene/
How is Li Fraumeni syndrome managed or treated? ... Li Fraumeni syndrome can't be cured. Management focuses on early diagnosis through screening, which starts at ...
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59 Medical guidelines for Li–Fraumeni syndrome 2019, version 1.1
https://link.springer.com/article/10.1007/s10147-021-02011-w
There is currently no cancer preventive agent for individuals with TP53 pathogenic variant. Surgical treatments, such as risk-reducing bilateral ...
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60 Radiation Therapy for Choroid Plexus Carcinoma Patients ...
https://ar.iiarjournals.org/content/anticanres/35/5/3013.full.pdf
Abstract. Background: Choroid plexus carcinomas (CPCs) are rare pediatric tumors often associated with Li-Fraumeni. Syndrome (LFS), a germline mutation in ...
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61 Pediatric Li-Fraumeni Syndrome (LFS) - Children's Health
https://www.childrens.com/specialties-services/conditions/pediatrici-fraumeni-syndrome
Li-Fraumeni syndrome (LFS) means that several members of a family have been diagnosed with cancer at a young age. Learn more.
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62 Radiation-induced Angiosarcoma of the Breast in a Li ...
https://www.elsevier.es/en-revista-cirugia-espanola-english-edition--436-articulo-radiation-induced-angiosarcoma-breast-in-li-fraumeni-S2173507719300043
The treatment was completed with chemotherapy (carboplatin, docetaxel and trastuzumab), then hormone therapy (tamoxifen and Zoladex®). Due to the family history ...
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63 Adjuvant radiotherapy induces secondary tumor events in ...
https://www.annalsofoncology.org/article/S0923-7534(19)30364-3/fulltext
Background: Breast cancer (BrCa) patients with Li-Fraumeni Syndrome (LFS) ... while five were treated with lumpectomy plus postoperative radiotherapy.
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64 The First Approved Gene Therapy Product for Cancer Ad-p53 ...
https://www.liebertpub.com/doi/10.1089/hum.2017.218
Gendicine was the first-ever approved gene therapy drug, and also the ... Patients with Li–Fraumeni syndrome have loss of function (LOF) ...
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65 A new relative contraindication for breast conservation therapy
https://www.advancesradonc.com/article/S2452-1094(17)30199-9/pdf
Radiation for Li-Fraumeni syndrome is dis- couraged due to the high risk of secondary cancers in this population.1 Radiation in the setting of scleroderma ...
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66 Pediatric Case of Li–Fraumeni Syndrome in Honduras - Hindawi
https://www.hindawi.com/journals/cripe/2021/6612802/
Li–Fraumeni syndrome is an inherited, autosomal dominant disease. It is categorized as a rare disease caused by mutations of the TP53 gene, which causes ...
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67 a p53 gene-replacement therapy in Li–Fraumeni syndrome
https://www.futuremedicine.com/doi/10.2217/14796694.4.6.759
Theoretically, correction of p53 function in cancer developing in patients with Li–Fraumeni syndrome through treatment with Advexin will ...
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68 Early Cancer Detection in Li-Fraumeni Syndrome Patients ...
https://www.genomeweb.com/sequencing/early-cancer-detection-li-fraumeni-syndrome-patients-enabled-liquid-biopsy-test
"Li-Fraumeni is a good proving ground for CHARM, due to the overall high risk of developing a variety of cancer types and multiple cancers over ...
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69 Breast Metachronous Carcinoma and Sarcoma in a Young ...
https://www.oncogen.org/full-text/breast-metachronous-carcinoma-and-sarcoma-in-a-young-patient-leading-to-the-diagnosis-of-li-fraumeni-syndrome
Keywords: Li-Fraumeni Syndrome; Breast Cancer; Sarcoma; Trastuzumab ... In August 2017, two years after the accomplished adjuvant treatment, the patient ...
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70 Positively Living LFS, It's NOT a Death Sentence.
https://livinglfs.org/positively-living-lfs-its-not-a-death-sentence/
Odds are that Li-Fraumeni Syndrome is THE most devastating hereditary cancer syndrome that you have never heard of, unless of course you ...
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71 Clinician Management Resource for TP53(Li-Fraumeni ...
https://www.ambrygen.com/file/material/view/1585/Clinician_ManagementResources_TP53_1120_final.pdf
Clinical correlation with the patient's past medical history, treatments, surgeries and family history may lead to changes in clinical.
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72 Li-Fraumeni syndrome - wikidoc
https://www.wikidoc.org/index.php/Li-Fraumeni_syndrome
Diagnosis and treatment ... Li-Fraumeni Syndrome is diagnosed if the following three criteria are met: ... Genetic counseling and genetic testing ...
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73 Li-Fraumeni Syndrome - CancerConnect
https://news.cancerconnect.com/treatment-care/li-fraumeni-syndrome
Li-Fraumeni Syndrome ... A hereditary cancer predisposition syndrome most commonly associated with soft tissue sarcoma, osteosarcoma, pre- ...
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74 A new therapeutic basis for treating Li-Fraumeni Syndrome ...
https://www.oncotarget.com/article/183/text/
Li-Fraumeni Syndrome (LFS) is a rare autosomal dominant disorder characterized by germline mutations in TP53 and the early onset of multiple ...
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75 Metformin in Li Fraumeni (MILI) trial - NIHR Funding and Awards
https://www.fundingawards.nihr.ac.uk/award/NIHR131239
Background: Li Fraumeni Syndrome (LFS) is a rare autosomal dominant ... which showed that metformin treatment caused the same kind of cellular changes that ...
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76 Re-irradiation using proton therapy for radiation-induced ...
https://www.cancerjournal.net/article.asp?issn=0973-1482;year=2020;volume=16;issue=6;spage=1524;epage=1527;aulast=Iwasaki
Li-Fraumeni syndrome (LFS) is a genetic disease that is hypersensitive to radiotherapy. Proton therapy (PT) was strongly recommended for ...
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77 adenoviral vector containing human p53 gene for the ...
https://www.ema.europa.eu/documents/orphan-designation/eu/3/06/404-public-summary-positive-opinion-orphan-designation-adenoviral-vector-containing-human-p53-gene_en.pdf
for the treatment of Li-Fraumeni syndrome. On 23 October 2006, orphan designation (EU/3/06/404) was granted by the European Commission to.
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78 A Diagnosis of Li-Fraumeni Syndrome Has Focused My Life ...
https://ascopost.com/issues/december-10-2018/a-diagnosis-of-li-fraumeni-syndrome-has-focused-my-life-direction/
I had decided against adjuvant radiation therapy. Before beginning treatment, I learned through genetic testing that I have Li-Fraumeni ...
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79 Spinal Tumor - Types, Causes, and Diagnoses - Cottage Health
https://www.cottagehealth.org/services/neuroscience/brain-spine-tumor-program/types-causes-diagnosis/
Learn the types, symptoms and treatments of spinal tumors. ... Neurofibromatosis Type 1 (NF1) or Type 2 (NF2); Li-Fraumeni syndrome; Tuberous sclerosis ...
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80 Li-Fraumeni Syndrome and the Role of the Pediatric Nurse ...
https://www.ons.org/cjon/15/1/li-fraumeni-syndrome-and-role-pediatric-nurse-practitioner
Li-Fraumeni syndrome (LFS) is an inherited cancer syndrome that affects a small percentage of the population worldwide. LFS is characterized by multiple ...
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81 Risk management for young people with inherited cancer
https://www1.racgp.org.au/ajgp/2021/august/risk-management-for-young-people-with-inherited-ca
Li-Fraumeni syndrome (LFS) is a rare, inherited cancer syndrome that affects many organ systems from birth and requires intensive, whole-body cancer risk ...
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82 Li-Fraumeni syndrome (LFS) - ERN Genturis
https://www.genturis.eu/l=eng/Thematic-disease-groups/Other-rare-genturis/Li-Fraumeni-Syndrome.html
Li-Fraumeni syndrome, also known as Heritable TP53-related cancer ... second tumour developed in a field irradiated during the treatment of a first tumour; ...
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83 Li–Fraumeni Syndrome (LFS) | Rare Cancer Predisposition ...
https://www.medindia.net/patientinfo/li-fraumeni-syndrome-lfs.htm
Currently there is no standard treatment or cure for LFS. Most people with LFS who develop cancers are treated in the same manner as for cancers ...
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84 What is Li-Fraumeni Syndrome? | Dana-Farber Cancer Institute
https://www.youtube.com/watch?v=VRZHquT9ZLg
Dana-Farber Cancer Institute
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85 The Risk of Prostate Cancer in Men with Inherited Germline ...
https://www.urotoday.com/video-lectures/mcrpc-treatment/video/2470-the-risk-of-prostate-cancer-in-men-with-inherited-germline-tp53-variants-kara-maxwell.html
Li-Fraumeni syndrome (LFS) inherited condition increased risk of cancer, ... but just the treatment for prostate cancer actually has so many ...
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86 Invitae Li-Fraumeni Syndrome Test | Test catalog
https://www.invitae.com/en/providers/test-catalog/test-01705
Li-Fraumeni syndrome (LFS) is a rare cancer predisposition condition associated with a high risk of developing soft tissue sarcoma, osteosarcoma, lung cancer, ...
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87 At Increased Risk | Duke Cancer Institute
http://www.dukecancerinstitute.org/news/increased-risk
She got surgical treatment near her home and moved on. ... The testing revealed that she has Li Fraumeni Syndrome (LFS), which means she has ...
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88 Li-Fraumeni Syndrome: Symptoms, Causes, Treatments
https://www.lifepersona.com/li-fraumeni-syndrome-symptoms-causes-treatments
There is no cure for cancer or for genetic abnormalities associated with Li-Fraumeni syndrome. The therapeutic approach is usually based on the standard ...
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89 Advancing Molecular Epidemiology
https://www.aacr.org/about-the-aacr/newsroom/pioneers-and-innovators/advancing-molecular-epidemiology/
Fraumeni, MD, and Frederick P. Li, MD, defined one of the first cancer predisposition syndromes linked to the most commonly mutated gene across ...
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90 Treatment for Brain Tumors | VCU Massey Cancer Center
https://www.masseycancercenter.org/cancer-types-and-treatments/cancer-types/brain-tumors/treatment
Radiation therapy is a cancer treatment that uses high-energy x-rays or other types of radiation to kill cancer cells or keep them from growing.
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91 Never a Dull Moment : Li Fraumeni Syndrome | - Mamachel.com
https://mamachel.com/health/womens-health/never-a-dull-moment-li-fraumeni-syndrome/
However, after treatment to help determine how we'd monitor the situation ... I was diagnosed with Li Fraumeni syndrome a rare disorder that ...
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92 Oncology | medRxiv
https://www.medrxiv.org/collection/oncology?page=6
Design and validation of an automated radiation therapy treatment planning ... of selection pressures and variants similar to Li-Fraumeni Syndrome mutations.
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93 Genetic testing leads to diagnoses for Southington wife, mother
https://www.wtnh.com/news/health/genetic-testing-leads-to-diagnoses-for-southington-wife-mother/
Parents with Li-Fraumeni syndrome have a 50% chance of passing it down to their children, giving them a high risk for childhood cancer. Johnson ...
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94 Login - NCCN
https://www.nccn.org/login
Guidelines COVID-19 Resources Treatment by Cancer Type Detection, Prevention, and Risk Reduction Supportive Care Specific Populations Guidelines for ...
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95 Li-Fraumeni Syndrome Association - Home | Facebook
https://www.facebook.com/lfsassociation/
Our hopes are to educate, raise awareness and find better screening programs and treatments for LFS. By forming relationships with and supporting the variety of ...
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