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1 Miller School Selected for National NF2 Tumor Clinical Trial
https://physician-news.umiamihealth.org/miller-school-selected-for-national-nf2-tumor-clinical-trial/
A University of Miami Miller School of Medicine researcher is hoping an innovative multicenter clinical trial will lead to new therapies for ...
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2 Accelerating gene therapy to cure NF2 -
https://nf2biosolutions.org/
Gene therapy targets the underlying cause of a disease and has the potential to replace the faulty NF2 gene with a healthy copy of the gene or to cause existing ...
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3 New drug approved for NF2 treatment
https://www.nfnetwork.org/pages-news/new-drug-approved-for-nf2-treatment/
BXCL101 is the first and only systemic therapy being developed to eliminate existing lesions and prevent the formation of new lesions by ...
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4 New experimental treatment can stop the growth of ...
https://www.sciencedaily.com/releases/2022/11/221108120242.htm
Inhibition of YAP/TAZ-driven TEAD activity prevents growth of NF2-null schwannoma and meningioma. Brain, 2022; DOI: 10.1093/brain/awac342.
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5 Drug-Based Treatments (Clinical Trials)
https://www.nf2is.org/clinical_trials.php
There is no cure to neurofibromatosis type 2 (NF2). There are limits to tumor-drug treatments for tumors that grow as a result of the NF2 ...
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6 News - Recursion Investor Relations
https://ir.recursion.com/2022-06-20-Recursion-Announces-Initiation-of-Phase-2-3-Trial-for-the-Treatment-of-NF2-Mutated-Meningiomas-at-Childrens-Tumor-Foundation-NF-Conference
REC-2282 is a CNS-penetrant, orally bioavailable, small molecule pan-HDAC inhibitor being developed for the treatment of NF2-mutated meningiomas ...
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7 Neurofibromatosis Neurofibromatosis Clinical Trials Consortium
https://cdmrp.health.mil/nfrp/clinical_trials/nf2.aspx
Summary: This Phase 2 trial will determine the response rate to crizotinib in children and adult NF2 patients with vestibular schwannomas, and ...
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8 Children's Tumor Foundation Announces New NF2 Clinical Trial
https://www.ctf.org/news/new-nf2-clinical-trial-intuitt-for-nf2
In that process, Takeda's Brigatinib (an approved drug for use in non-small cell lung cancer unrelated to NF) was discovered to show robust ...
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9 Innovative Trial for Understanding the Impact ... - Clinical Trials
https://clinicaltrials.gov/ct2/show/NCT04374305
Subjects with Neurofibromatosis Type 2 (NF2) and progressive vestibular schwannoma (VS) will be treated with crizotinib administered orally.
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10 Neurofibromatosis Type 2 (NF2) - Johns Hopkins Medicine
https://www.hopkinsmedicine.org/health/conditions-and-diseases/neurofibromatosis/neurofibromatosis-type-2
Radiotherapy can address vestibular schwannomas. Drug treatments for NF2-related tumors are currently under investigation, and may provide more options in the ...
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11 Neurofibromatosis Type 2 Clinic - Overview
https://www.mayoclinic.org/departments-centers/neurofibromatosis-type-2-clinic/overview/ovc-20481871
Chemotherapy. Chemotherapy uses drugs to stop tumor growth and, in some cases, to improve certain signs and symptoms of NF2 , such as hearing ...
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12 Neurofibromatosis Type 2 Diagnosis & Treatment - NYC
https://www.neurosurgery.columbia.edu/patient-care/conditions/neurofibromatosis-type-2
Neurofibromatosis type 2 (NF2) is a rare genetic condition characterized by tumors in the peripheral and central nervous system.
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13 Neurofibromatosis type 2 - Treatment - NHS
https://www.nhs.uk/conditions/neurofibromatosis-type-2/treatment/
There is currently no cure for NF2, so management focuses on regular monitoring and treating problems as and when they arise.
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14 Neurofibromatosis Type 2: Current Trends and Future ...
https://www.intechopen.com/chapters/70156
There are currently no FDA-approved biologic therapies for the treatment of NF2. Given the complexity and far-reaching effects of Merlin, multiple molecular ...
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15 Neurofibromatosis clinical trials at University of California Health
https://clinicaltrials.ucbraid.org/neurofibromatosis
Subjects with Neurofibromatosis Type 2 (NF2) and progressive vestibular schwannoma (VS) will be treated with crizotinib administered orally.
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16 Recursion Announces Initiation of Phase 2/3 Trial for the ...
https://www.yahoo.com/now/recursion-announces-initiation-phase-2-115500943.html
REC-2282 is a CNS-penetrant, orally bioavailable, small molecule pan-HDAC inhibitor being developed for the treatment of NF2-mutated meningiomas ...
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17 MSK Leads the Way in Neurofibromatosis Research and ...
https://www.mskcc.org/news/msk-leads-way-neurofibromatosis-research-and-treatment
Selumetinib received Breakthrough Therapy Designation earlier this year from the FDA to treat NF1. The drug is also being studied in clinical ...
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18 Treatment and Medical Management of Neurofibromatosis ...
https://www.uab.edu/medicine/nfprogram/learn/neurofibromatosis-type-2-nf2/treatment-management
Cochlear implants might be used in NF2 patients with bilateral hearing loss. The implant consists of a device surgically implanted under the skin near the ear ...
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19 Nonsteroidal sulfamate derivatives as new therapeutic ...
https://bmcpharmacoltoxicol.biomedcentral.com/articles/10.1186/s40360-019-0369-8
Current treatment options for NF2 tumours include surgical resection of either part of or the complete tumour, which is difficult to perform ...
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20 Antihypertension drug may benefit patients with ...
https://www.news-medical.net/news/20210715/Antihypertension-drug-may-benefit-patients-with-neurofibromatosis-type-2.aspx
New research led by investigators at Massachusetts General Hospital and Massachusetts Eye and Ear indicates that the blood pressure drug ...
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21 Recursion is Granted FDA Fast Track Designation for REC ...
https://www.prnewswire.com/news-releases/recursion-is-granted-fda-fast-track-designation-for-rec-2282-for-the-potential-treatment-of-nf2-mutated-meningiomas-301394829.html
NF2-mutated meningiomas are typically treated with surgery and radiotherapy or with off-label therapies of limited or unproven efficacy. The ...
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22 Innovative Trial for Understanding the Impact of Targeted ...
https://www.mayo.edu/research/clinical-trials/cls-20508593
This Master Study is being conducted as a "basket" study that may allow people with multiple tumor types associated with NF2 to receive new ...
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23 Gene replacement therapy in a schwannoma mouse model of ...
https://www.cell.com/molecular-therapy-family/methods/fulltext/S2329-0501(22)00091-2
These studies establish that merlin re-expression via gene replacement in NF2-null schwannomas is sufficient to cause tumor regression, thereby ...
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24 Current Clinical Trials - Neurofibromatosis (NF) Center
https://nfcenter.wustl.edu/research/participate-in-research/current-clinical-trials/
Our clinical trials aim to determine how drugs and other therapies can prevent or treat medical problems seen in individuals with NF1 and NF2.
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25 Step taken towards non-surgical treatment for schwannomas
https://www.braintumourresearch.org/media/news/news-item/2022/11/08/step-taken-towards-non-surgical-treatment-for-schwannomas
New treatments for schwannoma and other NF2-related tumours such as meningioma are urgently required. NF2 is caused by a faulty copy of a ...
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26 Rationale and Design of BeatNF2 Trial - MDPI
https://www.mdpi.com/1718-7729/28/1/71
Neurofibromatosis type 2 (NF2) causes bilateral vestibular schwannomas (VSs), leading to deafness. VS is treated by surgery or radiation, ...
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27 Neurofibromatosis Type 2 - Cancer.Net
https://www.cancer.net/cancer-types/neurofibromatosis-type-2
How are tumors related to NF2 treated? ... The primary method of treating tumors associated with NF2 is surgery. At the same time, many people with this disease ...
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28 Neurofibromatosis Type 2 (NF2) - Cleveland Clinic
https://my.clevelandclinic.org/health/diseases/16196-neurofibromatosis-type-2-nf2
Treatment of tumors varies. Some tumors aren't treated at all. Some, depending on size and location, might be treated with radiation or removed ...
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29 SEL-TH-1601: Phase 2 Trial of Selumetinib in Patients With ...
https://www.cincinnatichildrens.org/service/c/clinical-trials/studies/SEL-TH-1601
Since there is no standard effective chemotherapy for patients with NF2 and vestibular schwannomas, meningiomas, or ependymomas patients may be treated on this ...
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30 Neurofibromatosis Clinic - Massachusetts General Hospital
https://www.massgeneral.org/neurology/treatments-and-services/neurofibromatosis-clinic
Current clinic director Scott Plotkin, MD, PhD, has focused his research on identifying new medical treatments for NF. Ongoing Clinical Trials of NF1 & NF2.
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31 Neurofibromatosis type 2 - Genetics - MedlinePlus
https://medlineplus.gov/genetics/condition/neurofibromatosis-type-2/
The most common tumors associated with neurofibromatosis type 2 are called vestibular schwannomas. These growths develop along the nerve that ...
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32 Bevacizumab (Avastin®) treatment for Neurofibromatosis Type ...
https://www.ouh.nhs.uk/patient-guide/leaflets/files/13135Pavastin.pdf
Avastin stops the tumour from developing new blood vessels. ... Avastin is given for the treatment of NF2 initially for six months,.
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33 NF2 Therapy | NF2 Therapeutics, Inc. | United States
https://www.nf2tx.com/
NF2 Therapeutics, Inc. is a Cambridge based company focused on developing therapies for neurofibromatosis type 2 (NF2)
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34 Lessons learned from drug trials in neurofibromatosis
https://www.sciencedirect.com/science/article/pii/S1769721221001476
Most NF1 trials focused on plexiform neurofibromas (32%). Trials in NF2 solely studied vestibular schwannomas. In NF1, single-arm trials (58%) were most common, ...
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35 NF2-related schwannomatosis (formerly neurofibromatosis ...
https://www.uptodate.com/contents/nf2-related-schwannomatosis-formerly-neurofibromatosis-type-2
Alteration in a new gene encoding a putative membrane-organizing ... The diagnosis and management of neurofibromatosis 2 in childhood.
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36 Neurofibromatosis 2 - NORD (National Organization for Rare ...
https://rarediseases.org/rare-diseases/neurofibromatosis-2/
The treatment of vestibular (acoustic) neuromas associated with NF2 is the surgical removal of the tumors, when possible. The surgical procedure that is ...
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37 NF2 BioSolutions Is Accelerating Research to Cure a Rare ...
https://biobuzz.io/nf2-biosolutions-is-accelerating-research-to-cure-a-rare-tumor-disease/
Like most rare diseases out there, there is currently no true cure. NF2 BioSolutions, a non-profit based out of West Chester, Pennsylvania, is looking to change ...
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38 Neurofibromatosis Treatment - RWJBarnabas Health
https://www.rwjbh.org/treatment-care/neuroscience/neurosurgery/conditions-treated/neurofibromatosis/
Depending on a patient's symptoms, treatment for NF2 varies. Numerous nonsurgical treatments are available for vision and hearing problems. Physical or ...
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39 The Champion for Rare Disease Cures - NEO.LIFE
https://neo.life/2021/09/the-champion-for-rare-disease-cures/
Since his diagnosis with neurofibromatosis type 2 (NF2) in 2015, Onno has been on a quest to defy his prognosis and disrupt the rigged game of ...
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40 Neurofibromatosis 2 (NF2) - UC San Diego Health
https://health.ucsd.edu/specialties/surgery/otolaryngology/areas-expertise/acoustic-neuroma/pages/nf2.aspx
We work closely with our NF2 patients and their families to develop a customized treatment plan. See acoustic neuroma treatment. Content Area Two. New Patients
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41 Neurofibromatosis Type 2 and Schwannomatosis - UCLA Health
https://www.uclahealth.org/medical-services/neurosurgery/conditions-treated/neurofibromatosis-type-2-and-schwannomatosis
Neurofibromatosis: Neurofibromatosis type 2 (NF2) is a genetic condition caused ... to further our understanding of NF tumors and to develop new treatments.
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42 Study Demonstrates Efficacy of New Treatment for ...
https://www.chop.edu/news/study-demonstrates-efficacy-new-treatment-neurofibromatosis-type-1-related-tumors
Recent studies have shown that a MEK inhibitor called selumetinib can be an effective treatment in some children with NF1-related PNs, but not ...
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43 Neurofibromatosis Type 2 Diagnosis | Mount Sinai - New York
https://www.mountsinai.org/care/neurology/services/neurofibromatosis/types/type-2
The NF2 mutation causes the overgrowth of cells that wrap around and insulate nerves. The result is the growth of tumors known as schwannomas. NF2 patients are ...
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44 Innovative Trial for Understanding the Impact of Targeted ...
https://www.centerwatch.com/clinical-trials/listings/248387/innovative-trial-for-understanding-the-impact-of-targeted-therapies-in-nf2/
Drug Sub-study A will test the activity of brigatinib for treatment of NF2-related tumors. Brigatinib is approved for the treatment of people ...
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45 Brigatinib causes tumor shrinkage in both NF2-deficient ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0252048
Mice treated with brigatinib alone received the maximum tolerated dose of 50 mg/kg/qd. Due to in vivo toxicity in the preclinical model, the ...
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46 Neurofibromatosis – Symptoms, Diagnosis and Treatments
https://www.aans.org/en/Patients/Neurosurgical-Conditions-and-Treatments/Neurofibromatosis
There is no known treatment or cure for neurofibromatosis or schwannomatosis. Medication can be prescribed to help with pain. In some cases, growths may be ...
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47 Treatment of patients with advanced neurofibromatosis type 2 ...
https://ascopubs.org/doi/10.1200/jco.2011.29.15_suppl.2100
Background: There are minimal treatment options for advanced inoperable neurofibromatosis type 2(NF2), a rare and debilitating disorder ...
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48 Complex Care Streamlined for Neurofibromatosis 2
https://discover.vumc.org/2022/07/complex-care-streamlined-for-neurofibromatosis-2/
Generating New Knowledge ... Another aim of the NF2 clinic is to conduct research toward improving treatment, including outcomes studies and ...
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49 INTUITT-NF2 Clinical Trial Webinar (Captions available in ...
https://www.youtube.com/watch?v=Cqwf-jqQPM8
Childrens Tumor Foundation
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50 FDA approves first ever treatment for neurofibromatosis
https://www.eurekalert.org/news-releases/640598
The U.S. Food and Drug Administration (FDA) has approved Koselugo (selumetinib) for use in patients with inoperable plexiform neurofibromas, a ...
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51 Neurofibromatosis Type 2 | Boston Children's Hospital
https://www.childrenshospital.org/conditions/neurofibromatosis-type-2
How is NF2 treated? Since a cure for NF2 has not yet been found, treatment focuses on managing symptoms and complications. Experts here at Children's will ...
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52 Neurofibromatosis Type 2 (NF2) | Rush System
https://www.rush.edu/conditions/neurofibromatosis-type-2-nf2
Every case of NF2 is different, so your treatment will be tailored to meet ... your neurofibromatosis type 2 diagnosis and point to new treatment options.
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53 Neurofibromatosis Type II (NF2) - SBIR.gov
https://www.sbir.gov/sbirsearch/detail/1916283
pharmaceutical therapy and a limited clinical trial pipeline. NF Bio has developed an NF2 bacteriotherapy that utilizes intra-tumoral (i.t.) injection of ...
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54 Neurofibromatosis type-2 - Cancer Therapy Advisor
https://www.cancertherapyadvisor.com/home/decision-support-in-medicine/pediatrics/neurofibromatosis-type-2/
Most recently, in a retrospective analysis of 10 NF2 patients treated with bevacizumab the majority of patients showed radiographic and/or audiologic ...
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55 Neurofibromatosis Type 2 Treatment & Management
https://emedicine.medscape.com/article/1178283-treatment
Surgical resection of tumors remains the mainstay of treatment in neurofibromatosis type 2 (NF2), with recent advances in surgery permitting ...
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56 Focused Ultrasound Foundation and Children's Tumor ...
https://www.fusfoundation.org/posts/focused-ultrasound-foundation-and-childrens-tumor-foundation-partner-on-neurofibromatosis-study/
He and his team will use focused ultrasound to deliver a drug commonly used for lung cancer to a preclinical model of NF2. The drug will be ...
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57 Neurofibromatosis Institute | Children's National Hospital
https://childrensnational.org/departments/center-for-neuroscience-and-behavioral-medicine/programs-and-services/the-gilbert-family-neurofibromatosis-institute
Through clinical trials, your child has access to new treatments that are only available in select programs worldwide. Another aspect of our NF1 and NF2 ...
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58 Innovative Neurofibromatosis Treatment at University Hospitals
https://www.uhhospitals.org/services/Ear-Nose-and-Throat-Services/conditions-and-treatments/neurofibromatosis-2/treatments
NF2 also can be treated by use of the drug Avastin, an antibody anti-cancer medication. In some cases, Avastin has improved hearing loss and reduced tumor ...
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59 Neurofibromatosis 2 (NF2): Symptoms, Treatment, and More
https://www.healthline.com/health/neurofibromatosis
How Is NF2 Treated? ... There's no cure for either type of NF. However, your symptoms can be managed with treatment. Regular checkups and monitoring are important ...
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60 Radiographic regression of cranial meningioma in a NF2 ...
https://www.annalsofoncology.org/article/S0923-7534(19)38583-7/fulltext
Figure 1Volumetric evolution of intracranial tumors in a neurofibromatosis type 2 patient treated by bevacizumab for 15 months. The largest growing parietal ...
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61 Neurofibromatosis | Condition
https://utswmed.org/conditions-treatments/neurofibromatosis/
We have the latest treatment options supported by our ability to leverage new treatments through clinical trials for our patients.
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62 Qu-Du-San-Jie decoction induces growth inhibition and ...
https://www.frontiersin.org/articles/10.3389/fphar.2022.941854/full
Traditional treatment options for NF2-associated VS usually cause neurological damage, and to date, there are no FDA-approved pharmacotherapies ...
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63 Comprehensive Neurofibromatosis Center
https://nyulangone.org/locations/comprehensive-neurofibromatosis-center
We are committed to researching better and safer treatments for people with NF. We lead clinical trials for NF, and are the only New York member of the ...
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64 NF2 Research Updates - Issuu
https://issuu.com/childrenstumor/docs/ctf_newsletter-spring_2020-final_5-7__2_/s/10527970
Approximately 45% of pathogenic variants detected in the NF2 gene could be potentially treated with antisense therapy. Dr. Castellanos-Perez's team is well- ...
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65 UCSF Neurofibromatosis Clinical Trials for 2022
https://clinicaltrials.ucsf.edu/neurofibromatosis
Do you qualify for these Neurofibromatosis studies? ... 1 (NF1) and plexiform neurofibromas treated with the MEK inhibitor, binimetinib.
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66 Crizotinib Plus Radiation May Reduce NF2 Related Hearing ...
https://www.nfcr.org/blog/crizotinib-plus-radiation-may-reduce-nf2-related-hearing-loss/
A study co-authored by NFCR Fellow Dr. Rakesh Jain hints that adding crizotinib to the radiation therapy for tumors associated with ...
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67 Hearing Improvement after Bevacizumab in Patients with ...
https://www.nejm.org/doi/full/10.1056/NEJMoa0902579
Ten consecutive patients with neurofibromatosis type 2 and progressive vestibular schwannomas who were not candidates for standard treatment ...
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68 Christine Dinh, University of Miami – Multicenter National…
https://www.aacu.org/podcasts/academicminute/2022-08-christine-dinh-university-of-miami-multicenter-national-clinical-trial-for-neurofibromatosis-type-2
In order to better understand and treat this disease, a national multicenter, multispecialty clinical trial called INTUITT-NF2 is examining new ...
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69 NF2 research program - AllStripes
https://www.allstripes.com/program/nf2
AllStripes is a Public Benefit Corporation on a mission to unlock new treatments for people affected by rare disease. Learn more. ConditionsIndividualsPatient ...
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70 Current Management of Large Vestibular Schwannomas for ...
https://onlinelibrary.wiley.com/doi/full/10.1002/lary.28998
Among 54 NF2 patients with Koos IV VS (mean maximum extrameatal diameter: 34 mm; range:17–62 mm), 27 were operated on for 28 VS; 21 were treated ...
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71 New Gene Therapy at a World-Renowned Research Insitute
https://nervetumours.org.uk/news/new-gene-therapy-at-a-world-renowned-research-insitute/P9
There is a new NF2 Gene Therapy Pilot Pre-Clinical Study at the Abigail Wexner Research Institute at Nationwide Children's Hospital (NCH) by ...
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72 Neurofibromatosis Center » Department of Neurology »
https://neurology.ufl.edu/divisions/neurofibromatosis-center/
EXCITING NEWS, University of Florida, NF clinic is excited to be the site for NF-2's first clinical trial in patients suffering from progressive… Read Story.
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73 NF2 - NF Patients United
https://www.nf-patients.eu/what-is-nf/nf2/
The affected people are born with a genetic mutation in the NF2 gene. This affects the production of a protein called „Merlin“. There is no cure or special ...
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74 Establishing priorities in neurofibromatosis research - Nature
https://www.nature.com/articles/gim200145
... understanding the biology of the neurofibromatoses (NF1 and NF2) offers hope for the development of new, effective methods of treatment.
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75 Recursion Launches Clinical Trial for Targeted Drug in NF2 ...
https://www.precisiononcologynews.com/cancer/recursion-launches-clinical-trial-targeted-drug-nf2-mutated-meningioma-patients
NEW YORK – Recursion announced on Monday the launch of a Phase II/III trial evaluating its histone deacetylase (HDAC) inhibitor REC-2282 for ...
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76 Advancing Gene Therapy Research for a Devastating Rare ...
https://www.kbfcanada.ca/en/stories/advancing-gene-therapy-research-for-a-devastating-rare-disease/
Meyer, who adds that patients have been instrumental to pursuing new treatments for NF2. “They're not only fundraising, they're also donating ...
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77 Rationally combining anti-VEGF therapy with radiation in NF2 ...
https://www.rarediseasesjournal.com/articles/rationally-combining-antivegf-therapy-with-radiation-in-nf2-schwannoma.pdf
VS, and VEGF expression level positively correlates with schwannoma growth rate5-7. A 2009 New England. Journal of Medicine study led by Scott Plotkin, MD, ...
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78 Neurofibromatosis Type 2 | Manchester Centre for Genomic ...
https://www.mangen.co.uk/healthcare-professionals/clinical-genomic-services/nf2/
... half of patients have a new mutation. The Manchester genetics laboratory has facilities for diagnostic and predictive testing for NF2.
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79 Bevacizumab (Avastin) in Neurofibromatosis Type II | CUH
https://www.cuh.nhs.uk/patient-information/bevacizumab-avastin-in-neurofibromatosis-type-ii/
It is also used to treat some types of cancer. The reason that we think it is effective in the treatment of growing schwannomas in NF2 is that it stops the ...
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80 Targeted Therapy Development for Neurofibromatosis Type 2
https://stars.library.ucf.edu/etd/5732/
First line treatment for NF2 is watchful waiting and surgical removal of tumors, potentially resulting in facial paralysis and deafness.
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81 Anti-VEGF treatment improves neurological function ... - PNAS
https://www.pnas.org/doi/10.1073/pnas.1512570112
Treatment with bevacizumab is associated with tumor control and hearing improvement in neurofibromatosis type 2 (NF2) patients; however, its effect is not ...
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82 Essential signaling in NF2 loss-related tumours: the ...
https://jtd.amegroups.com/article/view/15835/html
To investigate whether mTOR signaling sustains NF2-mutated cancer cells during CRL4DCAF1 blockade, Cooper et al. treated mesothelioma tumor xenografts with ...
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83 9. Emerging Therapies for the Treatment of Patients with ...
https://www.cns.org/guidelines/browse-guidelines-detail/9-emerging-therapies-treatment-of-patients-with-ve
Level 3: It is recommended bevacizumab be administered to improve hearing or prolong time to hearing loss in patients with NF2 without surgical options.
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84 Synodos NF2 - syn2343195 - Wiki
https://www.synapse.org/synodosNF2
The end goal of this effort is to find new approaches to the diagnosis and treatment of two primary NF2-related tumors: schwannoma and meningioma.
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85 Phase II Trial of SMO/ AKT/ NF2/CDK Inhibitors in Progressive ...
https://www.yalemedicine.org/clinical-trials/vismodegib-and-fak-inhibitor-gsk2256098-in-treating-patients-with-progressive-meningiomas
This phase II trial studies how well vismodegib, focal adhesion kinase (FAK) inhibitor GSK2256098, and capivasertib work in treating ...
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86 Neurofibromatosis (NF) Program - ColumbiaDoctors
https://www.columbiadoctors.org/childrens-health/pediatric-specialties/genetics-inherited-disorders/innovative-programs-services/neurofibromatosis-nf-program
The Neurofibromatosis Program, located in NewYork-Presbyterian Morgan Stanley Children's Hospital, provides comprehensive care for people with NF1, NF2, ...
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87 Neurofibromatosis Multidisciplinary Clinic
https://www.wakehealth.edu/locations/clinics/n/neurofibromatosis-multidisciplinary-clinic
Researchers. Medical Conditions Treated. Neurofibromatosis type 1 (NF1) · Neurofibromatosis type 2 (NF2); Schwannomatosis. Partners and Affiliations. We ...
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88 Neurofibromatosis - MD Anderson Cancer Center
https://www.mdanderson.org/cancer-types/neurofibromatosis.html
Why choose MD Anderson for your neurofibromatosis treatment? · Clinical Trials. MD Anderson patients have access to clinical trials offering promising new ...
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89 New member on the TGE Online Giving Platform: NF2 ...
https://www.transnationalgiving.eu/new-member-on-the-tge-online-giving-platform-nf2-biosolutions.htm
Together, they created NF2 BioSolutions in 2018, with the goal to jumpstart novel therapy research on NF2. NF2 BioSolutions' mission is to find ...
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90 Microsurgery for patients diagnosed with neurofibromatosis t...
https://journals.lww.com/md-journal/Fulltext/2018/04270/Microsurgery_for_patients_diagnosed_with.4.aspx
These results suggest that PAK1 is essential for the malignant growth of NF2-deficient cells, and that PAK1-blocking drugs could be potentially useful for the ...
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91 A New Treatment for Children With Neurofibromatosis Type 1
https://jamanetwork.com/journals/jama/fullarticle/2766145
Selumetinib is the first drug approved for pediatric patients aged 2 years or older with neurofibromatosis type 1 (NF1), a rare disfiguring ...
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92 Neurofibromatosis type 2 - Healthily
https://www.livehealthily.com/health-library/conditions/neurofibromatosis-type-2
How it's treated ... There is currently no cure for NF2. Treatment involves regular monitoring and treating any problems that occur. Surgery can be used to remove ...
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93 Crizotinib-radiation therapy combination may help preserve ...
https://www.europeanpharmaceuticalreview.com/news/72461/crizotinib-radiation-therapy-nf2/
Crizotinib-radiation therapy combination may help preserve hearing in NF2 - Adding the targeted cancer therapy drug crizotinib to radiation ...
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