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Google Keyword Rankings for : can axons repair
1
Axon regeneration in the peripheral and central ... - PubMed
https://pubmed.ncbi.nlm.nih.gov/19582408/
Abstract. Axon regeneration in the mature mammalian central nervous system (CNS) is extremely limited after injury. Consequently, functional deficits persist ...
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https://pubmed.ncbi.nlm.nih.gov/19582408/
Abstract. Axon regeneration in the mature mammalian central nervous system (CNS) is extremely limited after injury. Consequently, functional deficits persist ...
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2
Axon Regeneration in the Central Nervous system
https://www.brc.cam.ac.uk/principal-investigators/james-fawcett/axon-regeneration-in-the-central-nervous-system/
Many forms of brain and spinal cord (CNS) damage cut axons. Where axons can regenerate, as in peripheral nerves, they can bring back function.
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https://www.brc.cam.ac.uk/principal-investigators/james-fawcett/axon-regeneration-in-the-central-nervous-system/
Many forms of brain and spinal cord (CNS) damage cut axons. Where axons can regenerate, as in peripheral nerves, they can bring back function.
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3
A Clearer Path to Axon Regeneration for Brain and Spinal ...
https://www.hopkinsmedicine.org/news/articles/a-clearer-path-to-axon-regeneration-for-brain-and-spinal-cord-injuries
Overcoming the inhibitory environment around the axon has led to the discovery that glial cells, which suppress axon regeneration, can be ...
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https://www.hopkinsmedicine.org/news/articles/a-clearer-path-to-axon-regeneration-for-brain-and-spinal-cord-injuries
Overcoming the inhibitory environment around the axon has led to the discovery that glial cells, which suppress axon regeneration, can be ...
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4
Functional Electrical Stimulation and the Modulation of the ...
https://www.frontiersin.org/articles/10.3389/fcell.2020.00736/full
Each axon exhibits a distinct response to injury in the adult. As described above, the peripheral axon retains the ability to regenerate ...
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https://www.frontiersin.org/articles/10.3389/fcell.2020.00736/full
Each axon exhibits a distinct response to injury in the adult. As described above, the peripheral axon retains the ability to regenerate ...
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5
The Struggle to Make CNS Axons Regenerate - Springer Link
https://link.springer.com/article/10.1007/s11064-019-02844-y
Axon regeneration in the form of peripheral nerve repair has been in clinical practice since the 12th Century and possibly before, but spinal ...
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https://link.springer.com/article/10.1007/s11064-019-02844-y
Axon regeneration in the form of peripheral nerve repair has been in clinical practice since the 12th Century and possibly before, but spinal ...
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6
Can injured adult CNS axons regenerate by recapitulating ...
https://journals.biologists.com/dev/article/144/19/3417/48177/Can-injured-adult-CNS-axons-regenerate-by
In the adult mammalian central nervous system (CNS), neurons typically fail to regenerate their axons after injury. During development, by ...
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https://journals.biologists.com/dev/article/144/19/3417/48177/Can-injured-adult-CNS-axons-regenerate-by
In the adult mammalian central nervous system (CNS), neurons typically fail to regenerate their axons after injury. During development, by ...
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7
Axonal fusion: An alternative and efficient mechanism of nerve ...
https://www.sciencedirect.com/science/article/pii/S0301008218301643
Reconnection between severed neuronal fibers occurs spontaneously in some invertebrate species and can be induced in mammalian systems. This process, known as ...
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https://www.sciencedirect.com/science/article/pii/S0301008218301643
Reconnection between severed neuronal fibers occurs spontaneously in some invertebrate species and can be induced in mammalian systems. This process, known as ...
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8
Factors influencing the regeneration of axons in the ... - Nature
https://www.nature.com/articles/sc199142.pdf?origin=ppub
repair the CNS, techniques will have to be developed to replace dead neurons, and induce axon regrowth. Central to the technologies necessary for brain ...
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https://www.nature.com/articles/sc199142.pdf?origin=ppub
repair the CNS, techniques will have to be developed to replace dead neurons, and induce axon regrowth. Central to the technologies necessary for brain ...
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9
Neural Injury & Repair - UCSD Neurosciences
https://neurosciences.ucsd.edu/research/interest-groups/neural-injury-repair.html
CNS axons are known to have very limited ability to regenerate after injury. Scientists are rapidly discovering the molecular determinants of axon regeneration ...
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https://neurosciences.ucsd.edu/research/interest-groups/neural-injury-repair.html
CNS axons are known to have very limited ability to regenerate after injury. Scientists are rapidly discovering the molecular determinants of axon regeneration ...
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10
Neuroregeneration - Wikipedia
https://en.wikipedia.org/wiki/Neuroregeneration
Neuroregeneration refers to the regrowth or repair of nervous tissues, cells or cell products. Such mechanisms may include generation of new neurons, glia, ...
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https://en.wikipedia.org/wiki/Neuroregeneration
Neuroregeneration refers to the regrowth or repair of nervous tissues, cells or cell products. Such mechanisms may include generation of new neurons, glia, ...
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11
Healing Neurological Damage After Stroke or Spinal Cord Injury
https://medicine.yale.edu/news-article/healing-neurological-damage-after-stroke-or-spinal-cord-injury-axon-regeneration-could-be-key-to-rebuilding-neural-connections/
But axon repair will remain relevant. Though traumatic brain injury can kill cells, it can also disrupt networks. Repeated mild blows to the head, ...
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https://medicine.yale.edu/news-article/healing-neurological-damage-after-stroke-or-spinal-cord-injury-axon-regeneration-could-be-key-to-rebuilding-neural-connections/
But axon repair will remain relevant. Though traumatic brain injury can kill cells, it can also disrupt networks. Repeated mild blows to the head, ...
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12
Making Axons Branch and Grow to Help Nerve Regeneration ...
https://drexel.edu/news/archive/2013/march/nerve-axon-growth
When nerves repair themselves after injury, there is currently no way to control their pattern of regrowth. But, “if you can induce longer ...
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https://drexel.edu/news/archive/2013/march/nerve-axon-growth
When nerves repair themselves after injury, there is currently no way to control their pattern of regrowth. But, “if you can induce longer ...
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13
Neuroregeneration - Center for Regenerative Biotherapeutics
https://www.mayo.edu/research/centers-programs/center-regenerative-biotherapeutics/focus-areas/neuroregeneration
Spinal cord repair. Regrowth of nerve fibers (axons) is essential to repair and functional recovery of the spinal cord. Tissue destruction with cysts and ...
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https://www.mayo.edu/research/centers-programs/center-regenerative-biotherapeutics/focus-areas/neuroregeneration
Spinal cord repair. Regrowth of nerve fibers (axons) is essential to repair and functional recovery of the spinal cord. Tissue destruction with cysts and ...
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14
Profiling sensory neuron microenvironment after peripheral ...
https://elifesciences.org/articles/68457
... can be manipulated to promote axon regeneration after central injury. ... and central axon injury reveals key pathways for neural repair.
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https://elifesciences.org/articles/68457
... can be manipulated to promote axon regeneration after central injury. ... and central axon injury reveals key pathways for neural repair.
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15
The metalloprotease ADM-4/ADAM17 promotes axonal repair
https://www.science.org/doi/10.1126/sciadv.abm2882
Axonal fusion is an efficient means of repair following axonal transection, whereby the regenerating axon fuses with its own separated ...
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https://www.science.org/doi/10.1126/sciadv.abm2882
Axonal fusion is an efficient means of repair following axonal transection, whereby the regenerating axon fuses with its own separated ...
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16
Axonal Regeneration in the Peripheral Nervous System of ...
https://academic.oup.com/book/5879/chapter/149178844
The progressive but slow advancement of regenerating axons from the proximal nerve across the site of nerve transection and repair severely slows the progress ...
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https://academic.oup.com/book/5879/chapter/149178844
The progressive but slow advancement of regenerating axons from the proximal nerve across the site of nerve transection and repair severely slows the progress ...
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17
First step to induce self-repair in the central nervous system
https://www.sciencedaily.com/releases/2019/07/190711141256.htm
Damaged peripheral nerves can regenerate after an injury, for example, following a forearm fracture. Axons, the long projections of neurons that ...
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https://www.sciencedaily.com/releases/2019/07/190711141256.htm
Damaged peripheral nerves can regenerate after an injury, for example, following a forearm fracture. Axons, the long projections of neurons that ...
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18
Repair in the central nervous system | The Bone & Joint Journal
https://online.boneandjoint.org.uk/doi/10.1302/0301-620X.89B11.19651
It was observed long ago that severed axons in the CNS do not have the ability to regrow any significant distance, and the prevailing belief was ...
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https://online.boneandjoint.org.uk/doi/10.1302/0301-620X.89B11.19651
It was observed long ago that severed axons in the CNS do not have the ability to regrow any significant distance, and the prevailing belief was ...
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19
Molecule shown to repair damaged axons | The Neuro
https://www.mcgill.ca/neuro/channels/news/molecule-shown-repair-damaged-axons-266571
A foray into plant biology led one researcher to discover that a natural molecule can repair axons, the thread-like projections that carry ...
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https://www.mcgill.ca/neuro/channels/news/molecule-shown-repair-damaged-axons-266571
A foray into plant biology led one researcher to discover that a natural molecule can repair axons, the thread-like projections that carry ...
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20
Axonal Regeneration from Injured Neurons in the Adult ...
https://web.as.uky.edu/biology/faculty/cooper/Bio535/CNS%20repair%20chapter.pdf
Interventive Strategies for Central Nervous System Repair ... Certain nerve cells in the adult brain and spinal cord can regrow axons for.
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https://web.as.uky.edu/biology/faculty/cooper/Bio535/CNS%20repair%20chapter.pdf
Interventive Strategies for Central Nervous System Repair ... Certain nerve cells in the adult brain and spinal cord can regrow axons for.
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21
Self-Repairing Nerve Cells - News Medical
https://www.news-medical.net/health/Self-Repairing-Nerve-Cells.aspx
In higher animals like mammals, PNS axons regenerate after peripheral nerve damage spontaneously whereas, CNS axons do not regenerate after ...
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https://www.news-medical.net/health/Self-Repairing-Nerve-Cells.aspx
In higher animals like mammals, PNS axons regenerate after peripheral nerve damage spontaneously whereas, CNS axons do not regenerate after ...
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22
Project AxonRepair - Spinal cord repair - ERA-NET NEURON
https://www.neuron-eranet.eu/news-publications/publications/success-stories/project-axonrepair-spinal-cord-repair-neuron-intrinsic-brake/
There are two major obstacles to the regeneration of nerve fibres (referred to as axons) of central nervous system (CNS) neurons. First, CNS nerve cells do ...
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https://www.neuron-eranet.eu/news-publications/publications/success-stories/project-axonrepair-spinal-cord-repair-neuron-intrinsic-brake/
There are two major obstacles to the regeneration of nerve fibres (referred to as axons) of central nervous system (CNS) neurons. First, CNS nerve cells do ...
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23
Nerve Surgery & Nerve Repair - Rebecca Ayers
http://www.rebeccaayers.co.nz/procedures-and-information/hand-surgery/nerve-surgery-and-nerve-repair
When one of your nerves is cut or damaged, it will try to repair itself. The nerve fibres (axons) shrink back and 'rest' for about a month; then they begin ...
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http://www.rebeccaayers.co.nz/procedures-and-information/hand-surgery/nerve-surgery-and-nerve-repair
When one of your nerves is cut or damaged, it will try to repair itself. The nerve fibres (axons) shrink back and 'rest' for about a month; then they begin ...
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24
Comparison of neuroregeneration in central nervous system ...
https://www.oatext.com/comparison-of-neuroregeneration-in-central-nervous-system-and-peripheral-nervous-system.php
Nerve repair is more effective in the peripheral nervous system. Although peripheral axons can repair and form functional relationships, several factors such as ...
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https://www.oatext.com/comparison-of-neuroregeneration-in-central-nervous-system-and-peripheral-nervous-system.php
Nerve repair is more effective in the peripheral nervous system. Although peripheral axons can repair and form functional relationships, several factors such as ...
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25
Axon Injury & Repair - Hope Center for Neurological Disorders
https://hopecenter.wustl.edu/?page_id=85
Axon Injury & Repair Group investigators study many aspects of axon biology, including the cell biology and signaling mechanisms that underlie axonal and ...
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https://hopecenter.wustl.edu/?page_id=85
Axon Injury & Repair Group investigators study many aspects of axon biology, including the cell biology and signaling mechanisms that underlie axonal and ...
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26
What worms can teach us about repairing injured neurons
https://qbi.uq.edu.au/blog/2017/12/what-worms-can-teach-us-about-repairing-injured-neurons
When axons are injured, they can no longer transmit messages and function is affected. The neuron needs to repair that connection to ...
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https://qbi.uq.edu.au/blog/2017/12/what-worms-can-teach-us-about-repairing-injured-neurons
When axons are injured, they can no longer transmit messages and function is affected. The neuron needs to repair that connection to ...
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27
Chapter:5 Progress Toward Neuronal Repair and Regeneration
https://www.nap.edu/read/11253/chapter/7
Nevertheless, axon regrowth does not result in improved function unless the axons can stimulate and inhibit the correct cellular target, whether it is in ...
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https://www.nap.edu/read/11253/chapter/7
Nevertheless, axon regrowth does not result in improved function unless the axons can stimulate and inhibit the correct cellular target, whether it is in ...
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28
Neuroregeneration and plasticity: a review of the physiological ...
https://mmrjournal.biomedcentral.com/articles/10.1186/s40779-020-00259-3
When a CNS axon is placed outside its typical setting, such as in the permissive environment of a peripheral nerve, regeneration can be observed ...
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https://mmrjournal.biomedcentral.com/articles/10.1186/s40779-020-00259-3
When a CNS axon is placed outside its typical setting, such as in the permissive environment of a peripheral nerve, regeneration can be observed ...
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29
Conditioning Injury-Induced Spinal Axon Regeneration ...
https://www.jneurosci.org/content/25/7/1645
Sensory axons in the adult spinal cord do not regenerate after injury. This is essentially because of inhibitory components in the damaged CNS, ...
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https://www.jneurosci.org/content/25/7/1645
Sensory axons in the adult spinal cord do not regenerate after injury. This is essentially because of inhibitory components in the damaged CNS, ...
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30
Intraneuronal determinants of axon regeneration (Chapter 30)
https://www.cambridge.org/core/books/textbook-of-neural-repair-and-rehabilitation/intraneuronal-determinants-of-axon-regeneration/3856F26BF61140C81C16D327BFBC131B
However, because it is now clear that adult neurons are intrinsically less able to grow axons than are embryonic neurons, one approach to enhancing axon ...
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https://www.cambridge.org/core/books/textbook-of-neural-repair-and-rehabilitation/intraneuronal-determinants-of-axon-regeneration/3856F26BF61140C81C16D327BFBC131B
However, because it is now clear that adult neurons are intrinsically less able to grow axons than are embryonic neurons, one approach to enhancing axon ...
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31
Analysis of Influencing Factors of Repair Effect after Peripheral ...
https://www.hindawi.com/journals/cmmm/2021/8294267/
Even if repair surgery is performed early, the axon descends slowly after a high-position injury, and the distal nerve will inevitably undergo ...
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https://www.hindawi.com/journals/cmmm/2021/8294267/
Even if repair surgery is performed early, the axon descends slowly after a high-position injury, and the distal nerve will inevitably undergo ...
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32
Treating, repairing nervous system - Mayo Clinic Health System
https://www.mayoclinichealthsystem.org/hometown-health/speaking-of-health/treating-repairing-nervous-system
Injured nerve cells in the central nervous system typically do not regenerate. However, this part of the nervous system can reorganize in ...
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https://www.mayoclinichealthsystem.org/hometown-health/speaking-of-health/treating-repairing-nervous-system
Injured nerve cells in the central nervous system typically do not regenerate. However, this part of the nervous system can reorganize in ...
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33
Visual system repair: what's next? : Neural Regeneration ...
https://journals.lww.com/nrronline/Fulltext/2022/04000/Visual_system_repair__what_s_next_.24.aspx
In addition, it has been shown recently that regenerating axons can be myelinated using a combination of drugs (Wang et al., 2020).
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https://journals.lww.com/nrronline/Fulltext/2022/04000/Visual_system_repair__what_s_next_.24.aspx
In addition, it has been shown recently that regenerating axons can be myelinated using a combination of drugs (Wang et al., 2020).
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34
Existence of new neuron repair pathway discovered
https://www.psu.edu/news/research/story/existence-new-neuron-repair-pathway-discovered/
“We know that the axon side can repair itself,” says Rolls, “and we know a bunch of the molecular players. But we really didn't know whether ...
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https://www.psu.edu/news/research/story/existence-new-neuron-repair-pathway-discovered/
“We know that the axon side can repair itself,” says Rolls, “and we know a bunch of the molecular players. But we really didn't know whether ...
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35
'Dancing molecules' successfully repair severe spinal cord ...
https://news.northwestern.edu/stories/2021/11/dancing-molecules-successfully-repair-severe-spinal-cord-injuries/
The severed extensions of neurons, called axons, regenerated · Scar tissue, which can create a physical barrier to regeneration and repair, ...
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https://news.northwestern.edu/stories/2021/11/dancing-molecules-successfully-repair-severe-spinal-cord-injuries/
The severed extensions of neurons, called axons, regenerated · Scar tissue, which can create a physical barrier to regeneration and repair, ...
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36
30.6C: Regeneration of Nerve Fibers - Medicine LibreTexts
https://med.libretexts.org/Bookshelves/Anatomy_and_Physiology/Book%3A_Anatomy_and_Physiology_(Boundless)/30%3A_APPENDIX_B%3A_Development_and_Aging_of_the_Organ_Systems/30.6%3A_Development_of_the_Nervous_System/30.6C%3A_Regeneration_of_Nerve_Fibers
When an axon is damaged, the distal segment undergoes Wallerian degeneration, losing its myelin sheath. The proximal segment can either die ...
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https://med.libretexts.org/Bookshelves/Anatomy_and_Physiology/Book%3A_Anatomy_and_Physiology_(Boundless)/30%3A_APPENDIX_B%3A_Development_and_Aging_of_the_Organ_Systems/30.6%3A_Development_of_the_Nervous_System/30.6C%3A_Regeneration_of_Nerve_Fibers
When an axon is damaged, the distal segment undergoes Wallerian degeneration, losing its myelin sheath. The proximal segment can either die ...
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37
Intrinsic heterogeneity in axon regeneration - Portland Press
https://portlandpress.com/biochemsoctrans/article/doi/10.1042/BST20220624/232107/Intrinsic-heterogeneity-in-axon-regeneration
In the mammalian peripheral nervous system (PNS) or the lower vertebrate central nervous system (CNS), most neurons can regenerate extensively ...
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https://portlandpress.com/biochemsoctrans/article/doi/10.1042/BST20220624/232107/Intrinsic-heterogeneity-in-axon-regeneration
In the mammalian peripheral nervous system (PNS) or the lower vertebrate central nervous system (CNS), most neurons can regenerate extensively ...
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38
Maximizing Functional Axon Repair in the Injured Central ...
https://anatomypubs.onlinelibrary.wiley.com/doi/pdf/10.1002/dvdy.24536
Therapies that stimulate axon repair will be critical to restore function. Extensive axon regeneration can be induced by manipulation of ...
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https://anatomypubs.onlinelibrary.wiley.com/doi/pdf/10.1002/dvdy.24536
Therapies that stimulate axon repair will be critical to restore function. Extensive axon regeneration can be induced by manipulation of ...
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39
New strategies for restoring myelin on damaged nerve cells
https://answers.childrenshospital.org/myelin-damaged-axons-multiple-sclerosis/
In earlier research, He's lab discovered several treatments that could promote the regeneration of damaged axons in the optic nerve, but do not ...
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https://answers.childrenshospital.org/myelin-damaged-axons-multiple-sclerosis/
In earlier research, He's lab discovered several treatments that could promote the regeneration of damaged axons in the optic nerve, but do not ...
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40
Swimming Exercise Promotes Post-injury Axon Regeneration ...
https://www.eneuro.org/content/8/3/ENEURO.0414-20.2021
Accelerating axonal regeneration and subsequent functional restoration is a major challenge to the people with nervous system injury. Research ...
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https://www.eneuro.org/content/8/3/ENEURO.0414-20.2021
Accelerating axonal regeneration and subsequent functional restoration is a major challenge to the people with nervous system injury. Research ...
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41
Repairing spinal cord injuries with a protein that regulates ...
https://www.fiercebiotech.com/research/repairing-spinal-cord-injuries-a-protein-regulates-axon-regeneration
"We observed a lot of axon regrowth, which could be very significant clinically, since there currently are no regenerative treatments for spinal cord injury or ...
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https://www.fiercebiotech.com/research/repairing-spinal-cord-injuries-a-protein-regulates-axon-regeneration
"We observed a lot of axon regrowth, which could be very significant clinically, since there currently are no regenerative treatments for spinal cord injury or ...
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42
PI 3‐kinase delta enhances axonal PIP3 to ... - EMBO Press
https://www.embopress.org/doi/abs/10.15252/emmm.201911674
CNS axons lose the ability to regenerate with maturity, whilst PNS axons do not. This study shows that PIP3 levels decline in CNS neurons at the time when ...
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https://www.embopress.org/doi/abs/10.15252/emmm.201911674
CNS axons lose the ability to regenerate with maturity, whilst PNS axons do not. This study shows that PIP3 levels decline in CNS neurons at the time when ...
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43
The manipulation of spinal motor neuron axonal growth ...
https://www.biorxiv.org/content/10.1101/2021.11.13.468456.full.pdf
and more effective spinal cord repair strategy is imperative. 54. After SCI, spinal motor neurons, which reside below the lesion site, can still survive for ...
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https://www.biorxiv.org/content/10.1101/2021.11.13.468456.full.pdf
and more effective spinal cord repair strategy is imperative. 54. After SCI, spinal motor neurons, which reside below the lesion site, can still survive for ...
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44
Intraocular Delivery of a Collagen Mimetic Peptide Repairs ...
https://www.mdpi.com/1422-0067/23/6/2911/htm
These include glaucoma, in which sensitivity to intraocular pressure (IOP) causes early RGC axonal dysfunction, and optic nerve trauma, which causes rapid axon ...
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https://www.mdpi.com/1422-0067/23/6/2911/htm
These include glaucoma, in which sensitivity to intraocular pressure (IOP) causes early RGC axonal dysfunction, and optic nerve trauma, which causes rapid axon ...
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45
Nerve Fiber Regeneration in Toxic Peripheral Neuropathy
https://journals.sagepub.com/doi/10.1177/0192623319854089
This situation differs from that in the peripheral nervous system, where long-distance axon regeneration and substantial functional recovery can occur in the ...
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https://journals.sagepub.com/doi/10.1177/0192623319854089
This situation differs from that in the peripheral nervous system, where long-distance axon regeneration and substantial functional recovery can occur in the ...
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46
Optic nerve regeneration screen identifies multiple genes ...
https://www.cell.com/cell-reports/pdf/S2211-1247(21)00090-5.pdf
Validated regeneration-limiting genes do not show axotomy- regulated expression ... Repair via axonal growth is limited by extracellular in-.
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https://www.cell.com/cell-reports/pdf/S2211-1247(21)00090-5.pdf
Validated regeneration-limiting genes do not show axotomy- regulated expression ... Repair via axonal growth is limited by extracellular in-.
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47
Nano neuro knitting: Peptide nanofiber scaffold for brain repair ...
https://www.pnas.org/doi/10.1073/pnas.0600559103
To achieve axonal regeneration after injury in the CNS, several formidable barriers must be overcome, such as scar tissue formation after tissue injury, gaps in ...
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https://www.pnas.org/doi/10.1073/pnas.0600559103
To achieve axonal regeneration after injury in the CNS, several formidable barriers must be overcome, such as scar tissue formation after tissue injury, gaps in ...
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48
Peripheral Nerve Injury & Repair - Hand - Orthobullets
https://www.orthobullets.com/hand/6066/peripheral-nerve-injury-and-repair
15% elongation will disrupt axons. examples. "stingers" refer to neurapraxia from brachial plexus stretch injury. suprascapular nerve stretching injuries in ...
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https://www.orthobullets.com/hand/6066/peripheral-nerve-injury-and-repair
15% elongation will disrupt axons. examples. "stingers" refer to neurapraxia from brachial plexus stretch injury. suprascapular nerve stretching injuries in ...
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49
Study finds a key to nerve regeneration - UW–Madison News
https://news.wisc.edu/study-finds-a-key-to-nerve-regeneration/
Axons are long fibers on neurons that transmit nerve impulses. The peripheral nervous system, the signaling network outside the brain and spinal ...
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https://news.wisc.edu/study-finds-a-key-to-nerve-regeneration/
Axons are long fibers on neurons that transmit nerve impulses. The peripheral nervous system, the signaling network outside the brain and spinal ...
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50
Neural Tissue Engineering: Strategies for Repair and ...
https://www.annualreviews.org/doi/10.1146/annurev.bioeng.5.011303.120731
A key difference between the PNS and CNS is the capacity for peripheral nerves to regenerate; CNS axons do not regenerate appreciably in their native ...
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https://www.annualreviews.org/doi/10.1146/annurev.bioeng.5.011303.120731
A key difference between the PNS and CNS is the capacity for peripheral nerves to regenerate; CNS axons do not regenerate appreciably in their native ...
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51
Axonal Sprouting and Growth after Neural Injury
https://www.asnr.com/m/pages.cfm?pageid=3729
Of the mechanisms of tissue repair in stroke, the formation of new connections (axonal sprouting) in brain adjacent to the stroke site occurs in rodents, ...
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https://www.asnr.com/m/pages.cfm?pageid=3729
Of the mechanisms of tissue repair in stroke, the formation of new connections (axonal sprouting) in brain adjacent to the stroke site occurs in rodents, ...
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52
Mechanisms of neurite repair - eScholarship.org
https://escholarship.org/content/qt69s644mn/qt69s644mn_noSplash_a9dc2893e5f49b85b73ebca62a1ea449.pdf
With their partners, let-7 microRNAs, Lin28a/b participate in sensory axon regeneration [24]. In the. CNS, Lin28 can potentiate insulin-like growth factor-1 ( ...
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https://escholarship.org/content/qt69s644mn/qt69s644mn_noSplash_a9dc2893e5f49b85b73ebca62a1ea449.pdf
With their partners, let-7 microRNAs, Lin28a/b participate in sensory axon regeneration [24]. In the. CNS, Lin28 can potentiate insulin-like growth factor-1 ( ...
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53
The Application of Omics Technologies to Study Axon...
https://f1000research.com/articles/8-311
by A Tedeschi · 2019 · Cited by 9 —
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https://f1000research.com/articles/8-311
by A Tedeschi · 2019 · Cited by 9 —
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54
Myelin repair | MS Society
https://www.mssociety.org.uk/research/explore-our-research/emerging-research-and-treatments/myelin-repair
How can we repair and replace myelin? · Nerve cells signal for help when their myelin is damaged · When the signal reaches the OPCs, they travel to the site of ...
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https://www.mssociety.org.uk/research/explore-our-research/emerging-research-and-treatments/myelin-repair
How can we repair and replace myelin? · Nerve cells signal for help when their myelin is damaged · When the signal reaches the OPCs, they travel to the site of ...
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55
How does an axon grow? - Genes & Development
http://genesdev.cshlp.org/content/17/8/941.full
Taken together, these findings indicate that surviving neurons do not constitutively extend axons and that axon growth must be specifically signaled by ...
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http://genesdev.cshlp.org/content/17/8/941.full
Taken together, these findings indicate that surviving neurons do not constitutively extend axons and that axon growth must be specifically signaled by ...
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56
The Myelin Sheath & Axon Repair - Study.com
https://study.com/academy/lesson/the-myelin-sheath-axon-repair.html
Although neurons can't divide and make new neurons, some damage to the axon can be repaired. Axons might be crushed by pressure or severed in half during a ...
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https://study.com/academy/lesson/the-myelin-sheath-axon-repair.html
Although neurons can't divide and make new neurons, some damage to the axon can be repaired. Axons might be crushed by pressure or severed in half during a ...
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57
Potential Drug Targets for Neuroregeneration and Repair
https://medcraveonline.com/JAPLR/potential-drug-targets-for-neuroregeneration-and-repair.html
Inhibitory myelin and axonal debris not cleared rapidly after CNS injury, which may contribute to glial scar formation. The proximal axons ...
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https://medcraveonline.com/JAPLR/potential-drug-targets-for-neuroregeneration-and-repair.html
Inhibitory myelin and axonal debris not cleared rapidly after CNS injury, which may contribute to glial scar formation. The proximal axons ...
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58
Regeneration and repair in the CNS | MedLink Neurology
https://www.medlink.com/articles/regeneration-and-repair-in-the-cns
Inhibitors of axonal regeneration in myelin include Nogo, myelin-associated glycoprotein, and oligodendrocyte myelin glycoprotein. These can be blocked with ...
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https://www.medlink.com/articles/regeneration-and-repair-in-the-cns
Inhibitors of axonal regeneration in myelin include Nogo, myelin-associated glycoprotein, and oligodendrocyte myelin glycoprotein. These can be blocked with ...
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59
Peripheral Neurological Recovery and Regeneration
https://now.aapmr.org/peripheral-neurological-recovery-and-regeneration/
Scar formation at the injury site will block axonal regeneration. ... Repairs with grafts can sometimes result in poor functional outcomes as a consequence ...
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https://now.aapmr.org/peripheral-neurological-recovery-and-regeneration/
Scar formation at the injury site will block axonal regeneration. ... Repairs with grafts can sometimes result in poor functional outcomes as a consequence ...
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60
Repairing the Damaged Spinal Cord - Scientific American
https://www.scientificamerican.com/article/repairing-the-damaged-spinal-cord/
Although neurons in the central nervous system of adult mammals generally fail to regenerate damaged axons, this lapse does not stem from an ...
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https://www.scientificamerican.com/article/repairing-the-damaged-spinal-cord/
Although neurons in the central nervous system of adult mammals generally fail to regenerate damaged axons, this lapse does not stem from an ...
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61
Role of galectin-1 in regeneration and repair following nerve ...
https://healthresearchbc.ca/award/role-galectin-1-regeneration-and-repair-following-nerve-injury/
Injury to neurons and their axons can result in loss of sensory and motor function. Injury to the axons within the central nervous system (CNS), ...
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https://healthresearchbc.ca/award/role-galectin-1-regeneration-and-repair-following-nerve-injury/
Injury to neurons and their axons can result in loss of sensory and motor function. Injury to the axons within the central nervous system (CNS), ...
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62
Nerve regeneration and repair
https://www.tandfonline.com/doi/pdf/10.3109/17453678709146461
The results of peripheral nerve repair have ... volume and neurite growth can be induced, ... Axonal regeneration will occur level and within distal nerve.
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https://www.tandfonline.com/doi/pdf/10.3109/17453678709146461
The results of peripheral nerve repair have ... volume and neurite growth can be induced, ... Axonal regeneration will occur level and within distal nerve.
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63
Way to repair damaged neurons discovered by scientists at ...
https://www.thehindu.com/sci-tech/science/nbrc-researchers-discover-functional-recovery-mechanism-after-neuronal-injury/article20443364.ece
During regeneration, only the axons that successfully fuse with their distal counterparts contribute to functional recovery. Regrowth of the ...
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https://www.thehindu.com/sci-tech/science/nbrc-researchers-discover-functional-recovery-mechanism-after-neuronal-injury/article20443364.ece
During regeneration, only the axons that successfully fuse with their distal counterparts contribute to functional recovery. Regrowth of the ...
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64
New discovery gives hope that nerves could be repaired after ...
https://www.imperial.ac.uk/news/146106/new-discovery-gives-hope-that-nerves/
The researchers were interested in understanding how axons in the peripheral nervous system (PNS) make a vigorous effort to grow back when they ...
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https://www.imperial.ac.uk/news/146106/new-discovery-gives-hope-that-nerves/
The researchers were interested in understanding how axons in the peripheral nervous system (PNS) make a vigorous effort to grow back when they ...
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65
Why Is Axonal Regeneration An Example Of Neuroplasticity?
https://neuropraxis.com/resource/why-is-axonal-regeneration-an-example-of-neuroplasticity/
When a nerve cell is damaged, the brain will try to repair it by growing new nerve cells. This process is called axonal regeneration. This is an example of ...
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https://neuropraxis.com/resource/why-is-axonal-regeneration-an-example-of-neuroplasticity/
When a nerve cell is damaged, the brain will try to repair it by growing new nerve cells. This process is called axonal regeneration. This is an example of ...
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66
Cell biology of spinal cord injury and repair - JCI
https://www.jci.org/articles/view/90608
For example, fibroblast cell grafts support robust axon regeneration after SCI but do so only when they produce specific axon-stimulatory growth ...
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https://www.jci.org/articles/view/90608
For example, fibroblast cell grafts support robust axon regeneration after SCI but do so only when they produce specific axon-stimulatory growth ...
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67
Zinc is a critical regulator of cell death and axon regeneration ...
https://grantome.com/grant/NIH/R01-EY024481-01A1
Under normal conditions, neurons in the adult CNS cannot regenerate damaged axons, placing severe limitations on the amount of recovery that can occur after ...
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https://grantome.com/grant/NIH/R01-EY024481-01A1
Under normal conditions, neurons in the adult CNS cannot regenerate damaged axons, placing severe limitations on the amount of recovery that can occur after ...
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68
Don't lose your nerve: choosing the right path during axon ...
https://www.fredhutch.org/en/news/spotlight/2021/10/bs-isabella-dev.html
“The mammalian vagus nerve regenerates poorly after injury, which can result in loss of speech, difficulty swallowing, abnormal heart rate, and ...
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https://www.fredhutch.org/en/news/spotlight/2021/10/bs-isabella-dev.html
“The mammalian vagus nerve regenerates poorly after injury, which can result in loss of speech, difficulty swallowing, abnormal heart rate, and ...
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69
Nerve Repair with Help From Stem Cells
https://almanac.upenn.edu/articles/nerve-repair-with-help-from-stem-cells/
But to date, these efforts have not been completely successful. Recovery can fall short due to a failure to coax large numbers of regenerating ...
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https://almanac.upenn.edu/articles/nerve-repair-with-help-from-stem-cells/
But to date, these efforts have not been completely successful. Recovery can fall short due to a failure to coax large numbers of regenerating ...
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70
Binary scaffold facilitates in situ regeneration of axons and ...
https://pubs.rsc.org/en/content/articlelanding/2021/bm/d0bm02212h
The limited regrowth of transected axons and insufficient regeneration of lost neurons in adult mammals collectively hinder complete spinal cord injury ...
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https://pubs.rsc.org/en/content/articlelanding/2021/bm/d0bm02212h
The limited regrowth of transected axons and insufficient regeneration of lost neurons in adult mammals collectively hinder complete spinal cord injury ...
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71
Nerve Injury - Paralysis Center
https://www.paralysiscenter.org/nerve-injury
Nerves can regenerate, but sometimes require surgical assistance after a peripheral nerve has been injured, it will try and repair itself. When an axon is ...
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https://www.paralysiscenter.org/nerve-injury
Nerves can regenerate, but sometimes require surgical assistance after a peripheral nerve has been injured, it will try and repair itself. When an axon is ...
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72
Molecule Shown to Repair Damaged Axons - R&D World
https://www.rdworldonline.com/molecule-shown-to-repair-damaged-axons/
A foray into plant biology led one researcher to discover that a natural molecule can repair axons, the thread-like projections that carry ...
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https://www.rdworldonline.com/molecule-shown-to-repair-damaged-axons/
A foray into plant biology led one researcher to discover that a natural molecule can repair axons, the thread-like projections that carry ...
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73
Misdirection and guidance of regenerating axons after ...
https://thejns.org/view/journals/j-neurosurg/120/2/article-p493.xml
Misdirection of regenerating axons is one of the factors that can explain the limited results often found after nerve injury and repair.
→ Check Latest Keyword Rankings ←
https://thejns.org/view/journals/j-neurosurg/120/2/article-p493.xml
Misdirection of regenerating axons is one of the factors that can explain the limited results often found after nerve injury and repair.
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74
Nerve Repair and Regeneration | HuffPost Contributor
https://www.huffpost.com/entry/nerve-repair-and-regeneration_b_58b09963e4b0e5fdf619717f
When the axon is separated from the body, there will be degeneration of the axon and the degeneration will stop at the synapse and will not ...
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https://www.huffpost.com/entry/nerve-repair-and-regeneration_b_58b09963e4b0e5fdf619717f
When the axon is separated from the body, there will be degeneration of the axon and the degeneration will stop at the synapse and will not ...
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75
Axon regeneration versus axon sprouting after injury in the ...
https://www.researchgate.net/figure/Axon-regeneration-versus-axon-sprouting-after-injury-in-the-spinal-cord-1-Axons-in-the_fig1_260645285
Axonal repair is critical for functional recovery after injury of the central nervous system (CNS). We previously reported that neuronal PTEN deletion exhibits ...
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https://www.researchgate.net/figure/Axon-regeneration-versus-axon-sprouting-after-injury-in-the-spinal-cord-1-Axons-in-the_fig1_260645285
Axonal repair is critical for functional recovery after injury of the central nervous system (CNS). We previously reported that neuronal PTEN deletion exhibits ...
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76
Bonn Researchers Identify Key Proteins for the Repair ... - DZNE
https://www.dzne.de/en/news/press-releases/press/bonn-researchers-identify-key-proteins-for-the-repair-of-nerve-fibers/
The cells located there each have two axons: a central and a peripheral. The peripheral axon can regenerate after damage. It has long been known that the ...
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https://www.dzne.de/en/news/press-releases/press/bonn-researchers-identify-key-proteins-for-the-repair-of-nerve-fibers/
The cells located there each have two axons: a central and a peripheral. The peripheral axon can regenerate after damage. It has long been known that the ...
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77
Axon regeneration - Operative Neurosurgery
https://operativeneurosurgery.com/doku.php?id=axon_regeneration
Axon regeneration Axons within the peripheral nervous system are capable of regeneration, but full functional recovery is rare.
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https://operativeneurosurgery.com/doku.php?id=axon_regeneration
Axon regeneration Axons within the peripheral nervous system are capable of regeneration, but full functional recovery is rare.
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78
Central Nervous System Injury and Repair
https://www.grc.org/central-nervous-system-injury-and-repair-conference/2022/
This is in part due to lack of full understanding of this complex condition where in addition to the damage of axons, spinal cord injury leads to profound ...
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https://www.grc.org/central-nervous-system-injury-and-repair-conference/2022/
This is in part due to lack of full understanding of this complex condition where in addition to the damage of axons, spinal cord injury leads to profound ...
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79
Facilitation of axon regeneration by enhancing mitochondrial ...
https://rupress.org/jcb/article/214/1/103/38683/Facilitation-of-axon-regeneration-by-enhancing
Mature cortical neurons can regain axon regrowth capacity by enhancing ... mitochondrial anchoring in the maintenance of axonal branching through the AMPK ...
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https://rupress.org/jcb/article/214/1/103/38683/Facilitation-of-axon-regeneration-by-enhancing
Mature cortical neurons can regain axon regrowth capacity by enhancing ... mitochondrial anchoring in the maintenance of axonal branching through the AMPK ...
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80
Polyethylene Glycol Treatment for Peripheral Nerve Repair in ...
https://www.jneurology.com/articles/polyethylene-glycol-treatment-for-peripheral-nerve-repair-in-preclinical-models.html
The addition of calcium-free solutions such as methylene blue cause the axon ends to remain patent, and the added PEG, hydrophilic in nature, ...
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https://www.jneurology.com/articles/polyethylene-glycol-treatment-for-peripheral-nerve-repair-in-preclinical-models.html
The addition of calcium-free solutions such as methylene blue cause the axon ends to remain patent, and the added PEG, hydrophilic in nature, ...
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81
Effect of Delayed Peripheral Nerve Repair on Nerve ... - PLOS
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0056484
A dramatic decline in the number of regenerating motoneurons and myelinated axons in the distal nerve stump was observed in the 3- and 6-months ...
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https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0056484
A dramatic decline in the number of regenerating motoneurons and myelinated axons in the distal nerve stump was observed in the 3- and 6-months ...
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82
Scientists discover way to repair axon fibers in the nerves of a ...
https://www.dailymail.co.uk/health/article-11239701/Scientists-discover-way-repair-axon-fibers-nerves-damaged-spine.html
Scientists have discovered a molecule called TTK21 that can repair damage in the spine after a severe injury. Axons in the spine have no ...
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https://www.dailymail.co.uk/health/article-11239701/Scientists-discover-way-repair-axon-fibers-nerves-damaged-spine.html
Scientists have discovered a molecule called TTK21 that can repair damage in the spine after a severe injury. Axons in the spine have no ...
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83
[PDF] Misdirection and guidance of regenerating axons after ...
https://www.semanticscholar.org/paper/Misdirection-and-guidance-of-regenerating-axons-and-Ruiter-Spinner/4b831d737a459c77a2c061af3ce084aadb441d0d
Misdirection of regenerating axons is one of the factors that can explain the limited results often found after nerve injury and repair.
→ Check Latest Keyword Rankings ←
https://www.semanticscholar.org/paper/Misdirection-and-guidance-of-regenerating-axons-and-Ruiter-Spinner/4b831d737a459c77a2c061af3ce084aadb441d0d
Misdirection of regenerating axons is one of the factors that can explain the limited results often found after nerve injury and repair.
→ Check Latest Keyword Rankings ←
84
How injured nerves stop themselves from healing - EurekAlert!
https://www.eurekalert.org/news-releases/503856
The Bochum-based scientists showed that this protein is released at the nerve's lesion site and, as a result, keeps the axons at the injured ...
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https://www.eurekalert.org/news-releases/503856
The Bochum-based scientists showed that this protein is released at the nerve's lesion site and, as a result, keeps the axons at the injured ...
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85
Chapter 26: Repair and Regeneration in the Nervous System
https://quizlet.com/584336667/chapter-26-repair-and-regeneration-in-the-nervous-system-flash-cards/
- There are three types of repair that can occur when nervous tissue is damaged: 1. Regrowth of damaged peripheral axons. - When peripheral axons are damaged ( ...
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https://quizlet.com/584336667/chapter-26-repair-and-regeneration-in-the-nervous-system-flash-cards/
- There are three types of repair that can occur when nervous tissue is damaged: 1. Regrowth of damaged peripheral axons. - When peripheral axons are damaged ( ...
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86
Exercise, Neurotrophins, and Axon Regeneration in the PNS
https://journals.physiology.org/doi/full/10.1152/physiol.00028.2014
Knocking out BDNF in Schwann cells surrounding regenerating axons inhibits axon regeneration, but this can be reversed by exercise. Knocking out BDNF in both ...
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https://journals.physiology.org/doi/full/10.1152/physiol.00028.2014
Knocking out BDNF in Schwann cells surrounding regenerating axons inhibits axon regeneration, but this can be reversed by exercise. Knocking out BDNF in both ...
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87
Injured neurons revert to 'immature' state to regrow - Futurity
https://www.futurity.org/nerves-regeneration-injuries-1933722/
... for injured peripheral nerves to repair themselves, and we can see ... what biological processes occur as the cells regrow their axons.
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https://www.futurity.org/nerves-regeneration-injuries-1933722/
... for injured peripheral nerves to repair themselves, and we can see ... what biological processes occur as the cells regrow their axons.
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88
New technique could help repair nerve damage
https://www.princeton.edu/news/2020/10/27/new-technique-could-help-repair-nerve-damage
“Our hope is that using that technology, if axon reconnection occurs, that we will be able to see restoration of function,” Schwartz said.
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https://www.princeton.edu/news/2020/10/27/new-technique-could-help-repair-nerve-damage
“Our hope is that using that technology, if axon reconnection occurs, that we will be able to see restoration of function,” Schwartz said.
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89
Neuronal Cells May be Repaired?
https://www.braininjurysupport.org/neuronal-cells-future-repairs/
Neuronal cells may be repaired in the near future opening the potential to reverse brain damage, spinal cord injuries and the devastating ...
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https://www.braininjurysupport.org/neuronal-cells-future-repairs/
Neuronal cells may be repaired in the near future opening the potential to reverse brain damage, spinal cord injuries and the devastating ...
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90
Myelin Sheath - Multiple Sclerosis - WebMD
https://www.webmd.com/multiple-sclerosis/myelin-sheath-facts
Because of this, MS can weaken your muscles, damage your coordination, and, ... The sheath protects these fibers, known as axons, a lot like the insulation ...
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https://www.webmd.com/multiple-sclerosis/myelin-sheath-facts
Because of this, MS can weaken your muscles, damage your coordination, and, ... The sheath protects these fibers, known as axons, a lot like the insulation ...
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91
Zapping the nerves to promote nerve regeneration - LabRoots
https://www.labroots.com/trending/neuroscience/13111/zapping-nerves-promote-nerve-regeneration
Electrical stimulation (ES) has been used to prevent muscle atrophy post-nerve injury and also promote axonal sprouting in the 1980's and early ...
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https://www.labroots.com/trending/neuroscience/13111/zapping-nerves-promote-nerve-regeneration
Electrical stimulation (ES) has been used to prevent muscle atrophy post-nerve injury and also promote axonal sprouting in the 1980's and early ...
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92
Gene Expression Studies and Spinal Cord Injury Repair ...
https://futuretech.findinggeniuspodcast.com/podcasts/gene-expression-studies-and-spinal-cord-injury-repair-jacob-koffler-uc-san-diego-neural-engineering-lab/
The stem cell derives neuron in now can take the signal extent new Exxon to extend the new electrical wire. That would go down the spinal cord ...
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https://futuretech.findinggeniuspodcast.com/podcasts/gene-expression-studies-and-spinal-cord-injury-repair-jacob-koffler-uc-san-diego-neural-engineering-lab/
The stem cell derives neuron in now can take the signal extent new Exxon to extend the new electrical wire. That would go down the spinal cord ...
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93
Can damaged axons be repaired? - Movie Cultists
https://moviecultists.com/can-damaged-axons-be-repaired
After peripheral nerve injury, axons readily regenerate. ... This active process results in fragmentation and disintegration of the axon. Debris is removed.
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https://moviecultists.com/can-damaged-axons-be-repaired
After peripheral nerve injury, axons readily regenerate. ... This active process results in fragmentation and disintegration of the axon. Debris is removed.
→ Check Latest Keyword Rankings ←
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