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1 Secretion and Endocytosis - Medical Cell Biology
http://medcell.med.yale.edu/lectures/secretion_endocytosis.php
There are two types of secretion: constitutive and regulated. Constitutive secretion is the default pathway and is used primarily to replenish material at ...
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2 Constitutive secretion and regulated secretion - YouTube
https://www.youtube.com/watch?v=FUgQLYMXA0k
Shomu's Biology
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3 Secretion, Lysosomal and Endocytotic Pathways. - UBC Zoology
https://www.zoology.ubc.ca/~berger/B200sample/unit_9_secretion/secretion_endocytosis.htm
Overview: There are two different secretory pathways, the Regulated Pathway and the Constitutive Pathway. In the regulated pathway proteins are consolidated ...
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4 Regulated and constitutive secretion. Differential effects of ...
https://www.sciencedirect.com/science/article/pii/S0021925818459704
Many neural and endocrine cells possess two pathways of secretion: a regulated pathway and a constitutive pathway. Peptide hormones are stored in granules ...
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5 Regulated and constitutive secretion. Differential ... - PubMed
https://pubmed.ncbi.nlm.nih.gov/1309785/
Many neural and endocrine cells possess two pathways of secretion: a regulated pathway and a constitutive pathway.
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6 Molecular Determinants of Regulated Exocytosis | Diabetes
https://diabetesjournals.org/diabetes/article/51/suppl_1/S3/11819/Molecular-Determinants-of-Regulated-Exocytosis
The major difference between regulated and constitutive exocytosis is that, in regulated exocytosis, secretory materials are stably ...
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7 Regulated and Constitutive Secretion
https://www.jbc.org/article/S0021-9258(18)45970-4/pdf
protein synthesis indicate differences in the mecha- nisms for sorting ... found that the contents of constitutive and regulated secretory.
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8 Constitutive and Regulated Secretion of Proteins
https://www.annualreviews.org/doi/pdf/10.1146/annurev.cb.03.110187.001331
Regulated secretory cells also have another pathway for protein secretion, the constitutive pathway. Proteins leaving the cell by the consti tutive pathway are ...
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9 Regulated and Constitutive Secretion Studied In Vitro
https://link.springer.com/chapter/10.1007/978-3-642-78267-1_33
These are provided by vesicles that bud from the Golgi complex and fuse with the plasma membrane. This process occurs continuously in the absence of any ...
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10 Cellular Processes: Constitutive Secretion (Golgi) - VCAC
http://vcell.ndsu.nodak.edu/animations/constitutivesecretion/index.htm
Proteins can be secreted, or transferred out of a cell, by multiple pathways. Constitutive secretion is one of these processes. In constitutive secretion ...
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11 The constitutive and regulated secretory pathways. The ...
https://www.researchgate.net/figure/The-constitutive-and-regulated-secretory-pathways-The-constitutive-secretory-pathway_fig5_326246333
The constitutive and regulated secretory pathways. The constitutive secretory pathway ensures the renewal of proteins located in the plasma membrane and the ...
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12 Receptor-mediated regulation of constitutive secretion
https://www.cell.com/trends/cell-biology/fulltext/0962-8924(93)90002-I
The traditional distinction between regulated and constitutive secretion may have contributed to the general belief that the latter is insensitive to ...
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13 VWF secretion: what's in a name? | Blood - ASH Publications
https://ashpublications.org/blood/article/112/4/926/25239/VWF-secretion-what-s-in-a-name
Regulated secretion requires a stimulus to provoke protein release from storage granules, whereas constitutive secretion is continuous, requires ...
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14 constitutive secretory pathway Gene Ontology Term (GO ...
http://www.informatics.jax.org/vocab/gene_ontology/GO:0045054
A process of exocytosis found in all eukaryotic cells, in which transport vesicles destined for the plasma membrane leave the trans-Golgi network in a steady ...
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15 Intermediates in the constitutive and regulated secretory ...
https://rupress.org/jcb/article/117/3/539/20329/Intermediates-in-the-constitutive-and-regulated
Regulated secretory cells have two pathways that transport secreted proteins from the Golgi complex to the cell surface.
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16 Switching of cargo sorting from the constitutive to regulated ...
https://journals.physiology.org/doi/full/10.1152/ajpgi.00103.2020
In the regulated pathway, the proteins to be secreted to the lumen are packaged and stored in secretory granules (SGs) and are secreted upon ...
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17 QuickGO::Term GO:0045054
https://www.ebi.ac.uk/QuickGO/term/GO:0045054
Definition (GO:0045054 GONUTS page) ... positive regulation of constitutive secretory pathway ... regulation of protein localization to cell surface.
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18 Constitutive Secretion - Virtual Cell Animation Collection
https://vcell.science/project/constitutivesecretion
Constitutive secretion is one of the pathways by which proteins can be secreted, or transferred out of a cell. In constitutive secretion proteins are secreted ...
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19 Regulated versus Constitutive Secretion – A Major Form of ...
https://www.semanticscholar.org/paper/Regulated-versus-Constitutive-Secretion-%E2%80%93-A-Major-St%C3%B6ckli-Piper/c007601573c2f1f9029674e36512bfb808af3629
Semantic Scholar extracted view of "Regulated versus Constitutive Secretion – A Major Form of Intercellular Communication" by J. Stöckli et al.
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20 Lumenal protein sorting to the constitutive secretory pathway ...
https://journals.biologists.com/jcs/article/119/9/1833/29663/Lumenal-protein-sorting-to-the-constitutive
Newly synthesized secretory granule content proteins are delivered via the Golgi complex for storage within mature granules, ...
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21 Ca2+ regulation of constitutive vesicle trafficking
https://facultyopinions.com/prime/reports/b/11/6/
Classically, constitutive secretion is thought to be continuous and unregulated. This contrasts with the highly controlled, regulated secretory ...
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22 Solved Question 36 (1 point) What is the difference between
https://www.chegg.com/homework-help/questions-and-answers/question-36-1-point-difference-constitutive-regulated-secretion-regulated-secretion-secret-q60798490
a) In regulated secretion, the secreted substance is in very high concentrations in vesicles on the cytosolic side of the plasma membrane. Ob) Regulated ...
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23 cell bio chap 8 review Flashcards - Quizlet
https://quizlet.com/8150341/cell-bio-chap-8-review-flash-cards/
Has two secretions: constitutive secretion and regulatory secretion. Constitutive secretion materials are transported out of the cell into the extracellular ...
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24 Cytotoxic T-Lymphocyte Secretory Pathways
https://lvts.fr/Pages_html/Encyclopedies/FundamentalImmunology/ramiCOMMAND=applyStylesheet(interface.xsl,CH036S0401.pub)&p_userid=pau&found=.html
Such secretion has been categorized as either regulated, if the exocytosis occurs with preformed granules in response to a membrane signal, or constitutive, if ...
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25 Secretion in Alveolar Type II Cells at the Interface of ...
https://www.atsjournals.org/doi/10.1165/ajrcmb.25.3.4493
In a general sense, regulated exocytosis describes all secretory responses in which the rate of vesicle fusion events is controlled.
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26 Compare and contrast the regulated and constitutive secretory ...
https://homework.study.com/explanation/compare-and-contrast-the-regulated-and-constitutive-secretory-pathways-with-regard-to-the-types-of-material-carried-and-the-regulation-of-secretion.html
Once a molecule is targeted for this pathway, it is automatically secreted, so the secretion has minimal regulation. In contrast, the regulated secretory ...
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27 VAMP3/Syb and YKT6 are required for the fusion of ... - PLOS
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1006698
The constitutive secretory pathway delivers newly synthesised proteins and lipids to the cell surface and is essential for cell growth and ...
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28 A Targeted siRNA Screen to Identify SNAREs Required for ...
https://onlinelibrary.wiley.com/doi/full/10.1111/j.1600-0854.2010.01087.x
Constitutive secretion is an essential, conserved process that is required for the delivery of newly synthesized proteins and lipids to the ...
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29 Receptor-mediated regulation of constitutive secretion — Italian ...
https://moh-it.pure.elsevier.com/en/publications/receptor-mediated-regulation-of-constitutive-secretion
The traditional distinction between regulated and constitutive secretion may have ... membrane receptors can in fact modulate constitutive membrane traffic.
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30 Constitutive Secretion of Protease Nexin-1 by Glial Cells and ...
https://www.jneurosci.org/content/25/39/8995
The receptor-mediated regulation of PN-1 constitutive secretion may be an ... A different vesicle moved from top to bottom and did not fuse ...
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31 SOLVED: Consider the difference between regulated and ...
https://www.numerade.com/ask/question/consider-the-difference-between-regulated-and-constitutive-secretion-select-all-correct-answers-that-apply-__-in-constitutive-secretion-the-secretory-vesicles-fuse-with-the-plasma-membrane-a-25123/
Consider the difference between regulated and constitutive secretion. ... __ in constitutive secretion the secretory vesicles fuse with the plasma membrane ...
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32 What Regulates Secretion of Non-Stored Proteins by ...
http://deepblue.lib.umich.edu/bitstream/handle/2027.42/50183/950040507_ftp.pdf?sequence=1
ACTH.4.5 A summary of differences between the regulated and constitutive secretory pathway is shown in Table I. The mechanisms involved in the.
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33 Difference between regulated secretion and constitutive ...
https://brainly.in/question/11057210
Constitutive secretion is the default pathway and is used primarily to replenish material at the plasma membrane and certain membrane-bound ...
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34 Transport and the Molecular Mechanism of Secretion (Section ...
https://nba.uth.tmc.edu/neuroscience/m/s1/chapter10.html
The major difference is that vesicle trafficking during neurosecretion is regulated by Ca2+ influx whereas vesicle trafficking during the synthesis and ...
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35 Constitutive protein secretion from the trans -Golgi network to ...
https://www.tandfonline.com/doi/pdf/10.1080/0968768031000084172
use of different secreted 'cargo' or marker proteins such as influenza virus hemagglutinin (HA) ... the regulation of TGN-to-plasma membrane transport (re-.
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36 Elucidating the pathways and machinery of constitutive secretion
https://gtr.ukri.org/projects?ref=BB%2FL002841%2F1
Constitutive secretion is a fundamental cellular process required for the delivery of newly synthesised proteins and lipids to the plasma membrane as well as ...
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37 Regulated secretion | Genome Biology | Full Text
https://genomebiology.biomedcentral.com/articles/10.1186/gb-2000-1-1-reports402
Despite the apparent differences in cellular architecture and behavior of different cell types and of cells from organisms separated by long ...
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38 Depletion of Carboxypeptidase E, a Regulated Secretory ...
https://academic.oup.com/endo/article/139/4/2137/2988425
3), suggesting no major difference in neuroendocrine protein expression in these ... Constitutive secretion and the lack of proinsulin/insulini in punctate ...
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39 What is exocytosis? | MBInfo
https://www.mechanobio.info/what-is-the-plasma-membrane/what-is-membrane-trafficking/what-is-exocytosis/
The constitutive secretory pathway (orange arrow) directly delivers fresh membrane lipids and proteins to the cell membrane. The regulated pathway (green ...
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40 Regulation of protein secretion through chemical ... - Nature
https://www.nature.com/articles/s41467-022-28971-9
Response of protein secretion based on transcriptional control is rather slow, as it requires transcription, translation and transport from the ...
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41 Intermediates in the constitutive and regulated ... - Europe PMC
https://europepmc.org/article/med/1572894
Small constitutive secretory vesicles, containing mostly sulfated proteoglycans, accumulated during an in vitro incubation with ATP. In the presence of GTP ...
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42 Constitutive Secretion in Tetrahymena thermophila
https://journals.asm.org/doi/10.1128/EC.00024-10
Subsets of proteins from the T. thermophila regulated secretion pathway ... Secretome cross-comparisons revealed dramatic differences in the ...
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43 Pathways of Unconventional Protein Secretion
https://www.hubrecht.eu/app/uploads/2017/11/Rabouille_Key_2017_Rabouille_Pathways-of-unconventional-protein-secretion.pdf
different cell types as well as the pore they use to translocate is a key milestone ... Self-Made Lipidic Pores Mediate Constitutive Secretion of Fibroblast ...
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44 Ca2+ regulation of constitutive vesicle trafficking - Amazon S3
https://s3-eu-west-1.amazonaws.com/science-now.reports/f1000reports/files/9002/11/6/article.pdf
with opposing influences, through binding to different target proteins. Keywords ... a role as a regulator of constitutive secretion.
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45 Methods of discharge - The Statesman
https://www.thestatesman.com/supplements/science_supplements/methods-of-discharge-1502773089.html
Moreover, there are two different modes of secretion by eukaryotic cells. Constitutive secretion involves the continuous discharge of vesicles ...
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46 ScholarWorks at University of Montana
https://scholarworks.umt.edu/cgi/viewcontent.cgi?article=1334&context=biosci_pubs
Intermediates in the Constitutive and Regulated Secretory. Pathways Released In Vitro from Semi-intact Cells. Mark L. Grimes.
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47 Exocytosis - Wikipedia
https://en.wikipedia.org/wiki/Exocytosis
Exocytosis is the process by which a large amount of molecules are released; thus it is a form of bulk transport. Exocytosis occurs via secretory portals at ...
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48 a-biosynthetic-regulated-secretory-pathway-in-constitutive ...
https://typeset.io/pdf/a-biosynthetic-regulated-secretory-pathway-in-constitutive-2bzvzrsa85.pdf
known to block regulated and constitutive secretion, in- ... To compare the relative sizes of GAG-containing granules from CHO.
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49 Exocytosis and Endocytosis - StudySmarter
https://www.studysmarter.us/explanations/biology/cell-structure-and-function/exocytosis-and-endocytosis/
In contrast to constitutive secretion which takes place continuously in cells, regulated secretion occurs when specific conditions are met. Some examples in ...
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50 Role of Golgi Signaling Molecules in Cancer - Frontiers
https://www.frontiersin.org/articles/10.3389/fcell.2022.833663/full
Signaling molecules within autoregulatory circuits on the intracellular membranes of the secretory pathway regulate these processes, especially ...
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51 Protein secretion: Puzzling receptors - CORE
https://core.ac.uk/download/pdf/81129584.pdf
given protein in secretory granules relative to constitutive secretory vesicles, as is the case for the regulated secretory proteins, or to a failure of the ...
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52 Difference Between Endocytosis and Exocytosis - Pediaa.Com
https://pediaa.com/difference-between-endocytosis-and-exocytosis/
Exocytosis occurs by either constitutive secretory pathway or regulated secretory pathway. During constitutive secretory pathway, the contents ...
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53 (PDF) Discrimination between constitutive secretion and basal ...
https://www.academia.edu/21577514/Discrimination_between_constitutive_secretion_and_basal_secretion_from_the_regulated_secretory_pathway_in_GH3_cells
In the present study we have sought to distinguish between In neurons, ... Constitutive and regulated secretion of progastrin and the start of the chase ...
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54 Constitutive secretion of protease nexin-1 by glial cells and its ...
https://hal.archives-ouvertes.fr/hal-00017019/document
The receptor-mediated regulation of PN-1 constitutive secretion may be ... Scale bar, 10m.c, GFP/PN-1 and TGN38 are transported by different ...
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55 The trans-Golgi network: a late secretory sorting station Linton ...
https://sites.pitt.edu/~traub/publications/current.pdf
constitutive and the regulated secretory pathways [43••]. †In GH3 cells, ... Schematic illustrations of the different trafficking routes from the TGN.
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56 Endocytosis and Exocytosis: Differences and Similarities
https://www.technologynetworks.com/immunology/articles/endocytosis-and-exocytosis-differences-and-similarities-334059
The release of these molecules from the cell is termed regulated exocytosis because the expulsion of the materials is controlled, or regulated, ...
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57 Elucidating the pathways and machinery of constitutive secretion
https://app.dimensions.ai/details/grant/grant.3861879
Technical Summary Constitutive secretion is a fundamental cellular process required for the delivery of newly synthesised proteins and lipids to the plasma ...
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58 A novel carboxyl-terminal heptapeptide initiates the regulated ...
http://digitalcommons.wustl.edu/cgi/viewcontent.cgi?article=2576&context=open_access_pubs
Regulated Secretion of LH from Unique Sub-Domains of the ER ... cell line, which contains both, regulated and constitutive secretion pathways.
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59 A Definition of Exocytosis With Steps and Examples - ThoughtCo
https://www.thoughtco.com/what-is-exocytosis-4114427
Regulated exocytosis occurs commonly in secretory cells and not in all cell types. Secretory cells store products such as hormones, ...
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60 The cell. 5. Vesicular trafficking. Exocytosis. Atlas of plant and ...
https://mmegias.webs.uvigo.es/02-english/5-celulas/5-exocitosis.php
Two pathways target the plasma membrane. One is known as constitutive exocytosis, which is present in almost every cell, whereas the other is ...
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61 Partial Diversion of a Mutant Proinsulin (B10 Aspartic Acid ...
https://www.jstor.org/stable/33633
the regulated to the constitutive secretory pathway in transfected AtT-20 cells ... scribed for unlabeled cells, with one difference; the products.
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62 Partial diversion of a mutant proinsulin (B10 aspartic ... - PNAS
https://www.pnas.org/doi/10.1073/pnas.86.11.4107
These data indicate that a significant fraction of the mutant prohormone is released via the constitutive secretory pathway rather than the regulated pathway, ...
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63 The PKD-Dependent Biogenesis of TGN-to-Plasma ... - MDPI
https://mdpi-res.com/d_attachment/cells/cells-10-01618/article_deploy/cells-10-01618-v2.pdf?version=1625045263
The different organelles of the secretory pathway ... PKD is involved in both regulated and constitutive secretion. On the one hand, in.
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64 The exocyst complex is an essential component of ... - bioRxiv
https://www.biorxiv.org/content/10.1101/2022.05.26.493223v1
Secreted proteins fulfil a vast array of different functions, ... in specialised secretory cell types prevents the constitutive secretion of ...
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65 The constitutive secretory pathway is a major route for islet ...
https://scholars.duke.edu/display/pub1027031
We have previously reported that glucose stimulates IAPP, but not insulin secretion, from neonatal rat beta-cells when regulated secretion is prevented by use ...
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66 Cell Biology 04: The Secretory Pathway - CureFFI.org
https://www.cureffi.org/2013/02/24/cell-biology-04-the-secretory-pathway/
See redox if still confused. This makes for different protein-folding conditions: for instance, disulfide bonds usually only form in oxidative ...
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67 Endocytosis Vs Exocytosis - Definitions, Types of Exocytosis
https://www.microscopemaster.com/endocytosis-vs-exocytosis.html
The second type of exocytosis is known as regulated exocytosis. Unlike constitutive exocytosis, which is a continual process, regulated exocytosis is dependent ...
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68 GTPases in Biology I - Page 514 - Google Books Result
https://books.google.com/books?id=q0L1CAAAQBAJ&pg=PA514&lpg=PA514&dq=what+is+the+difference+between+regulated+and+constitutive+secretion&source=bl&ots=Sbw_qQoOSU&sig=ACfU3U3eH1JVt2QW2vEZIyQpZ05-JYV_kg&hl=en&sa=X&ved=2ahUKEwihjZiMs8H7AhUPjokEHRblD8cQ6AF6BQieAhAD
This may provide a mechanism for sorting and concentrating this class of ... the differences between the constitutive secretory pathway and the regulated ...
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69 Secretory Systems and Toxins - Page 221 - Google Books Result
https://books.google.com/books?id=dso7OUoeqMMC&pg=PA221&lpg=PA221&dq=what+is+the+difference+between+regulated+and+constitutive+secretion&source=bl&ots=C2Nv4bO3-o&sig=ACfU3U0AO4XkmXF6asLOtDz_PpuXyg_-qQ&hl=en&sa=X&ved=2ahUKEwihjZiMs8H7AhUPjokEHRblD8cQ6AF6BQifAhAD
The overwhelming similarity between constitutive and regulated systems ... To unveil the potential safety-latches, it is best to compare initiation and ...
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70 Regulated and Constitutive Secretory Pathways in Salivary ...
https://iadr.abstractarchives.com/abstract/2004Hawaii-47123/regulated-and-constitutive-secretory-pathways-in-salivary-cell-lines
PSP and amylase were secreted efficiently from transfected cells, but secretion was not enhanced by secretagogues, suggesting that the proteins did not enter a ...
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71 Dr. Hunter Cell Biology - intra-cellular trafficing - Google Sites
https://sites.google.com/site/drhunterscellpage/intra-cellular-trafficing
Discriminate between regulated and constitutive secretion. ... C. Example of uses & findings - vesicles from different parts of Golgi were found to have ...
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72 Virus Infection Activates IL-1β and IL-18 Production in Human ...
https://journals.aai.org/jimmunol/article/162/12/7322/1114/Virus-Infection-Activates-IL-1-and-IL-18
Constitutive expression of proIL-18 was seen in monocytes and macrophages, ... and protein secretion during microbial infections are regulated in a similar ...
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73 The Secretory Pathway: Randy Schekman - iBiology
https://www.ibiology.org/cell-biology/protein-secretion/
Randy Schekman provides a genetic dissection of the protein secretion pathway ... 00:04:30.06 So, enormous difference in complexity between a cell that has ...
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74 Quantitative Flow Cytometry-Based Assays for Measuring ...
https://experiments.springernature.com/articles/10.1007/978-1-0716-1044-2_8
Constitutive secretion is predominantly measured by collecting the media from cells and performing plate-based assays. This approach is particularly sensitive ...
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75 Pathways of Protein Secretion in Eukaryotes - Science
https://www.science.org/doi/pdf/10.1126/science.2994224
When both constitutive and regulated protein secretion can take place in the same ... end up at different locations in the cell.
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76 Encyclopedia of Cell Biology - Page 376 - Google Books Result
https://books.google.com/books?id=BEabBwAAQBAJ&pg=RA1-PA376&lpg=RA1-PA376&dq=what+is+the+difference+between+regulated+and+constitutive+secretion&source=bl&ots=7MjZNtvqrm&sig=ACfU3U3Fg0R0Z-72dKLTMHYqJa7aZ28r7w&hl=en&sa=X&ved=2ahUKEwihjZiMs8H7AhUPjokEHRblD8cQ6AF6BQiuAhAD
The concept of regulated versus constitutive secretion was first described almost 30 ... Differences among these systems are found in how they are made, ...
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77 Intracellular transport - Google Books Result
https://books.google.com/books?id=qr6rDAAAQBAJ&pg=PT32&lpg=PT32&dq=what+is+the+difference+between+regulated+and+constitutive+secretion&source=bl&ots=8D1xGdnRxU&sig=ACfU3U1MsnsPrA-EPA9_-b2LLi7r_pUP_Q&hl=en&sa=X&ved=2ahUKEwihjZiMs8H7AhUPjokEHRblD8cQ6AF6BQigAhAD
Identify the fundamental difference between constitutive and regulated secretion, in terms of their function within an organism and the ways in which this ...
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78 NOVEL MARKERS FOR CONSTITUTIVE SECRETION USED TO ...
https://ur.booksc.eu/book/1898863/2462a2
NOVEL MARKERS FOR CONSTITUTIVE SECRETION USED TO SHOW THAT TISSUE PLASMINOGEN ACTIVATOR IS SORTED TO THE REGULATED PATHWAY IN TRANSFECTED PC12 CELLS | T.M. ...
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79 Switching of cargo sorting from the constitutive to ... - GenScript
https://www.genscript.com/reference_peer-reviewed_literature_70951.html
Switching of cargo sorting from the constitutive to regulated secretory pathway by the addition of cystatin D sequence in salivary acinar cells.
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80 Zell's Popular Encyclopedia: A Complete Dictionary of the ...
https://books.google.com/books?id=pOlHAQAAMAAJ&pg=PA629&lpg=PA629&dq=what+is+the+difference+between+regulated+and+constitutive+secretion&source=bl&ots=7LFN25YNhp&sig=ACfU3U0-g50ig9CNHdvsRXkzb5MMa7qZcg&hl=en&sa=X&ved=2ahUKEwihjZiMs8H7AhUPjokEHRblD8cQ6AF6BQihAhAD
Power of * The elements and constitutive parts of a schismatic . ... of the bowels , or defective secretion of by three - fourths of the several States .
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