❤️ What Is The Difference Between Systemic Effect And Local Effect

Google Keyword Rankings for : what is the difference between systemic effect and local effect

1 Local Effect and Systemic Effect - De Gruyter
https://www.degruyter.com/database/IUPAC/entry/iupac.79.2238/html?lang=en
local effect. Local effects occur at the first site of contact on or in the body where application of the toxicant or exposure to it takes place. · systemic ...
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2 Systemic Effect - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/chemistry/systemic-effect
Systemic effects are defined as those effects occurring in tissues distant from the site of contact between the body and the medical device or biomaterial. From ...
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3 A. Local effects
http://www.nzdl.org/cgi-bin/library?e=d-00000-00---off-0cdl--00-0----0-10-0---0---0direct-10---4-------0-1l--11-en-50---20-about---00-0-1-00-0--4----0-0-11-10-0utfZz-8-10&cl=CL2.24&d=HASH6710fa6de7e2fc8ada357b.7.2>=1
2. Local effects occur at the place where the hazardous agent comes into contact with or enters the body. 3. Systemic effects occur inside the body once a ...
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4 Local versus systemic effects of inhaled drugs - PubMed
https://pubmed.ncbi.nlm.nih.gov/9474365/
However, all drugs deposited in the airways are eliminated via the systemic circulation, and have, therefore, the potential to cause some systemic side effects.
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5 COMMON ROUTES OF DRUG ADMINISTRATION
https://media.lanecc.edu/users/driscolln/RT114/Medication_Administration/Intro_Pharmacology/Intro_Pharmacology8.html
(via gastrointestinal tract) · (commonly refers to injections) · Systemic (gases, insulin now available in inhaler) or local effect (bronchodilator) aimed at ...
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6 What Is the Difference Between Local and Systemic Therapy?
https://abcnews.go.com/Health/OnCallPlusTreatment/difference-local-systemic-therapy/story?id=3643074
Systemic therapy involves therapy that's designed to kill cancer cells that have fled the breast by way of blood vessels to organs elsewhere in the body.
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7 Pharmacology Chapter 5 Flashcards | Quizlet
https://quizlet.com/316088972/pharmacology-chapter-5-flash-cards/
1. Describe the difference between local and systemic drug effects. A local effect is characterized by an aerosolized medication being deposited on the surface ...
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8 Appendix D. Chemicals Known to Cause Local and Systemic ...
https://www.epa.gov/sites/default/files/2015-05/documents/appendd.pdf
Toxicity to the Respiratory System Effects of inhaled respiratory toxicants were addressed above. Neurotoxicity Chemicals/Classes of compounds which may ...
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9 Applied Pharmacology 1, Systemic Drug Administration
https://www.youtube.com/watch?v=Sk88Tx8x0pA
Dr. John Campbell
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10 Drug Administration - Drugs - Merck Manuals Consumer Version
https://www.merckmanuals.com/home/drugs/administration-and-kinetics-of-drugs/drug-administration
Applied to the skin (cutaneously) for a local (topical) or bodywide (systemic) effect. Delivered through the skin by a patch (transdermally) for a systemic ...
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11 Local versus systemic effects of inhaled drugs
https://www.resmedjournal.com/article/S0954-6111(97)90103-7/fulltext
For all drugs, the therapeutic ratio, i.e, the difference between therapeutic effect and adverse effect, should be as large as possible.
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12 Understanding Toxic Substances: An Introduction to Chemical ...
https://www.purdue.edu/research/docs/pdf/Introduction%20to%20Chemical%20Hazards%20in%20the%20Workplace.pdf
The toxicity of a substance is its ability to cause harmful effects. ... A toxic chemical may cause local effects, systemic effects, or both. For example ...
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13 THE IMPORTANCE OF LOCAL DRUG DELIVERY
https://online.boneandjoint.org.uk/doi/10.1302/1358-992X.2018.16.096
COMPARISON OF SYSTEMIC AND LOCAL ADMINISTRATION OF BISPHOSPHONATES ... risk of side-effects, reduced site-specific drug delivery and hence, ...
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14 Route of administration - Wikipedia
https://en.wikipedia.org/wiki/Route_of_administration
Action may be topical (local), enteral (system-wide effect, but delivered through the gastrointestinal tract), or parenteral (systemic action, but delivered ...
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15 Understanding Toxic Substances - CDPH
https://www.cdph.ca.gov/Programs/CCDPHP/DEODC/OHB/HESIS/CDPH%20Document%20Library/introtoxsubstances.pdf
the different types of exposure limits for chemicals in the workplace, ... A toxic chemical may cause local effects, systemic effects, or both. For example ...
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16 Systemic: MedlinePlus Medical Encyclopedia
https://medlineplus.gov/ency/article/002294.htm
Systemic means affecting the entire body, rather than a single organ or body part. For example, systemic disorders, such as high blood ...
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17 Skin Exposures and Effects | NIOSH - CDC
https://www.cdc.gov/niosh/topics/skin/default.html
Occupational skin diseases are one of the most common types of workplace diseases. They can take different forms, such as: Rash (contact dermatitis) caused by ...
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18 Local Anesthetic Toxicity - Medscape Reference
https://emedicine.medscape.com/article/1844551-overview
The toxicity of local and infiltration anesthetics can be local or systemic. Local adverse effects include neurovascular manifestations such ...
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19 Solved What is the difference between a local effect and a
https://www.chegg.com/homework-help/questions-and-answers/difference-local-effect-systemic-effect-chemical-exposed-give-example-chemical-local-vs-sy-q54330332
Give an example of a chemical and its local vs systemic effect for each of the main routes of exposure noted above. What do you think are the advantages and ...
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20 Systemic and Local Effects of Heat Dissipation in the Therma...
https://journals.lww.com/asaiojournal/Abstract/1988/07000/Systemic_and_Local_Effects_of_Heat_Dissipation_in.45.aspx
No difference was shown between the two groups in hematologic parameters, plasma free hemoglobin, liver and renal function, fibrinogen levels, or coagulation ...
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21 Local versus systemic effects of inhaled drugs - CORE
https://core.ac.uk/download/pdf/82731229.pdf
For all drugs, the therapeutic ratio, i.e, the difference between therapeutic ... separation of their effects on lung function from their systemic effects.
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22 Vaccine side-effects and SARS-CoV-2 infection after ...
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(21)00224-3/fulltext
Systemic and local side-effects after BNT162b2 and ChAdOx1 nCoV-19 ... For each of the vaccines and for different timepoints from the ...
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23 Local anesthetic systemic toxicity - UpToDate
https://www.uptodate.com/contents/local-anesthetic-systemic-toxicity
Local anesthetics are often incorrectly thought to be without side effects or toxicity. LAST is always a potential complication, and may occur ...
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24 TOXICOLOGY - International occupational safety & health ...
https://www.ilo.org/legacy/english/protection/safework/cis/products/safetytm/toxic.htm
Local effects occur at the area of the body which has been in contact with the chemical. Examples are injuries from acids or lung injuries from ...
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25 Routes of Drug Administration: An Overview
https://www.pharmapproach.com/routes-of-drug-administration/
Drugs are applied topically, that is to the skin or mucous membrane of the eye, ear, nose, mouth, vagina, etc., mainly for local action. This route provides a ...
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26 LOCAL AND SYSTEMIC EFFECTS OF HEAT AND COLD IN ...
https://jamanetwork.com/journals/jamasurgery/fullarticle/549324
TEMPERATURE is one of the most powerful governors of life processes, since it affects nervous and circulatory functions, membrane permeability, ...
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27 Health Effects of Toxic Chemicals
https://ehs.utoronto.ca/our-services/chemical-and-lab-safety/whmis/whmis-information/health-effects-toxic-chemicals/
Exposure can be classified as chronic or acute. In chronic exposures, the dose is delivered at some frequency (daily or weekly usually) over a period of time.
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28 (Revised 1/03) TOXICOLOGY AND EXPOSURE GUIDELINES
https://ehs.unl.edu/documents/tox_exposure_guidelines.pdf
Some combinations of chemicals produce different effects ... chemicals can cause both local and systemic effects. Long-term effects (or chronic effects) are ...
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29 Irreversible Electroporation versus Radiofrequency Ablation
https://pubs.rsna.org/doi/full/10.1148/radiol.2015151166
To compare both periablational and systemic effects of two mechanistically ... Indeed, local hepatic or tumor RF ablation can stimulate ...
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30 4 explain the difference between local and systemic
https://www.coursehero.com/file/p76no9e/4-Explain-the-difference-between-local-and-systemic-effects-of-a-drug-Can-a/
4 Explain the difference between local and systemic effects of a drug Can a from NUR 239 at Illinois ... Can they have local effects of a systemic drug?
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31 Basic pharmacological principles - WSAVA2011 - VIN
https://www.vin.com/apputil/content/defaultadv1.aspx?pId=11343&id=5189569&print=1
Drugs are applied topically primarily for local effects, however this route can be used to administer drugs for systemic action. Few drugs readily penetrate ...
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32 Local effect of a drug - Medical Dictionary
https://medical-dictionary.thefreedictionary.com/local+effect+of+a+drug
local effect of a drug ... The impact of a therapeutic agent on specific tissues rather than on the whole body, esp. on those tissues where the agent is absorbed, ...
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33 5 Systemic Health Effects | Review of the Environmental ...
https://www.nap.edu/read/13142/chapter/8
However, it is important to distinguish between systemic delivery of formaldehyde and systemic effects. The possibility remains that systemic delivery of ...
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34 Importance of local versus systemic effects of non ... - Gut
https://gut.bmj.com/content/32/3/275
This increased small intestinal permeability may be a summation of a local effect during drug absorption, a systemic effect after absorption, and a local effect ...
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35 Corticosteroids - Cleveland Clinic
https://my.clevelandclinic.org/health/drugs/4812-corticosteroids
When possible, local steroid treatments are prescribed instead of systemic steroids to reduce the risk of side effects.
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36 Systemic but No Local Effects of Combined Zoledronate and ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0092359
Introduction Local bone erosions and osteoporosis in rheumatoid arthritis (RA) are the result of a more pronounced bone resorption than bone ...
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37 Definition of systemic - NCI Dictionary of Cancer Terms
https://www.cancer.gov/publications/dictionaries/cancer-terms/def/systemic
Affecting the entire body. Search NCI's Dictionary of Cancer Terms. Starts with. Contains.
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38 Introduction to toxicology - European Commission
https://ec.europa.eu/health/ph_projects/2003/action3/docs/2003_3_09_a21_en.pdf
toxicology is "the study of the adverse effects of chemicals or physical ... For example, potassium cyanide is a systemic toxicant in that it affects.
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39 Clinical Pharmacology of Corticosteroids - Respiratory Care
https://rc.rcjournal.com/content/63/6/655
Inhaled corticosteroids are potent synthetic agents that exert their actions locally in the airways but can cause systemic effects based on ...
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40 Skin penetration and tissue permeation after topical ...
https://www.tandfonline.com/doi/full/10.1080/03007995.2017.1352497
Although some of the drug does enter the systemic circulation from the dermal ... The risk of local effects was significantly higher with topical delivery, ...
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41 The MSDS HyperGlossary: Systemic
http://www.ilpi.com/msds/ref/systemic.html
Systemic effects usually display differing levels of toxicity to the various organs in your body. In most cases, the major effects are ...
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42 Routes of Drug Administration - KnowledgeDose
https://www.knowledgedose.com/routes-of-drug-administration/
The inhalation route is used for a local effect or systemic effect. The drug is inhaled through the mouth and delivered into the lungs.
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43 Systemic and local effects of metformin administration in ...
https://academic.oup.com/humrep/article/25/4/1005/697879
In both of these groups, and without difference between them, serum androgens and indices of insulin resistance improved significantly (P < 0.05) after ...
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44 Systemic and Local Corticosteroid Use Is Associated with ...
https://www.karger.com/Article/FullText/501617
In this study, we assessed the associations between the use of different corticosteroid types with cognitive and neuropsychiatric adverse effects related to ...
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45 Routes of Drug Administration
https://www.thieme.in/image/catalog/Sample%20Chapter/Bhandari%20sample%20chapter.pdf
Systemic absorption of drugs is minimal, hence systemic side effects can be avoided. Following are some of the local routes: Topical.
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46 Chloroform Toxicological overview - GOV.UK
https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/338535/Chloroform_Toxicological_Overview.pdf
Acute inhalation of chloroform can cause systemic effects such as excitement, ... Following acute dermal exposure to chloroform, local effects may include ...
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47 What is the effect of suppository after administration?
https://www.blissgvs.com/2016/12/26/what-is-the-effect-of-suppository-after-administration/
Systemic Effect: The systemic action for which suppositories are used, are limited only by the drug's solubility and absorbability.
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48 About Exposure - New York State Department of Health
https://www.health.ny.gov/environmental/about/exposure.htm
Then they may react to very low levels of the chemical and have different or more serious health effects than nonallergic people exposed to the same amount.
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49 Local and Systemic Protumorigenic Effects of Cancer ...
https://cancerres.aacrjournals.org/content/74/13/3408
Cancer-associated fibroblasts (CAF) stimulate tumor growth and progression, angiogenesis, and metastasis, are involved in the attraction of different cell types ...
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50 Local anesthetics: systemic toxicity - OpenAnesthesia
https://www.openanesthesia.org/local_anesthetics_systemic_toxicity/
These include the central nervous system and heart. The CNS is more sensitive to the effects of local anesthetics than the cardiac system and will generally ...
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51 Systemic effects of local allergic disease
https://www.jacionline.org/article/S0091-6749(03)02474-6/fulltext
Allergic reactions are not confined to the area they originated, but assume a secondary systemic, nonanaphylactic element.
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52 Local and Systemic Adverse Effects of Vaccinated Individuals ...
https://www.infectiousdiseaseadvisor.com/home/topics/covid19/adverse-effects-reported-in-the-covid-symptom-study-app/
The investigators adjusted the data to account for differences in the population, such as vaccine type, age, sex, healthcare worker status, and ...
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53 Drug Delivery: Localized and Systemic Therapeutic Strategies ...
https://link.springer.com/10.1007/978-3-319-92067-2_32-1
The importance of targeting polymeric materials to the desired site of action and the significant differences in treatment strategies that are present ...
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54 Key Principles of Toxicology and Exposure - CHEMM
https://chemm.hhs.gov/toxprinciples.htm
Dermal exposure - Chemicals in contact with the skin can cause local effect but may also enter the systemic circulation and cause effects at distant sites ...
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55 Skin and Eye Irritation - ChemSafetyPro.COM
https://www.chemsafetypro.com/Topics/CRA/Skin_and_Eye_Irritation.html
A systemic effect is defined as an effect that is normally observed distant from the site of first contact, i.e., after having passed through a ...
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56 Skin Drug Delivery: Local and Systemic Applications - MDPI
https://www.mdpi.com/journal/pharmaceutics/special_issues/skin_local_delivery
Application of drugs onto the skin is of great interest and may aim to achieve local or systemic effects. Although some drugs can effectively diffuse ...
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57 6.4 Administering Medications Rectally and Vaginally
https://opentextbc.ca/clinicalskills/chapter/6-4-rectal-and-vaginal-medications/
Rectal medications are given for their local effects in the gastrointestinal system (e.g., laxatives) or their systemic effects (e.g., analgesics when oral ...
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58 Systemic vs. topical psoriasis treatments: What to know
https://www.medicalnewstoday.com/articles/btc-systemic-vs-topical-psoriasis-treatments
What are the main differences between systemic and topical treatments for ... They do not have as many side effects as systemic medications.
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59 Routes of drug administration - WikiLectures
https://www.wikilectures.eu/w/Routes_of_drug_administration
We usually divide routes of drug administration that produce systemic effect in Enteral or Parenteral. From Greek Enteros = Intestine and ...
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60 Frequently Asked Questions About Topical Drug Delivery
https://www.tapemark.com/blog/topical-drug-delivery-faq
Can topical administration of a drug help to reduce side effects? ... Yes, because a topical drug provides treatment in one of two ways. It either ...
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61 Types of drugs | Britannica
https://www.britannica.com/science/drug-chemical-agent/Types-of-drugs
These different classification systems can be confusing, since each drug may be included ... of drugs can also achieve a systemic rather than local effect.
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62 Local Destruction of Tumors and Systemic Immune Effects
https://www.frontiersin.org/articles/10.3389/fonc.2021.708810/full
The terms used in Embase had small differences in wording with the intention to cover the same fields: (neoplasm OR cancer OR tumor) AND ( ...
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63 Local and systemic effects of IL-17 in joint inflammation - Nature
https://www.nature.com/articles/s41423-021-00644-5
They first showed that IL-17A used alone had relatively modest effects on different cell types compared to the activities of the key ...
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64 Fluoride: Topical and Systemic Supplements
https://www.ada.org/resources/research/science-and-research-institute/oral-health-topics/fluoride-topical-and-systemic-supplements
An overview of the many ways fluoride is used topically and ... potentially decreasing the decay-preventive effects of optimally fluoridated ...
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65 Comparison of systemic and local effects of nitric acid and ...
https://jag.journalagent.com/z4/download_fulltext.asp?pdir=travma&plng=tur&un=08208-TRA
Comparison of systemic and local effects of nitric acid and hydrochloric acid: an experimental study in a rat model. Nitrik ve hidroklorik asidin sistemik ...
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66 Bioavailability and Bioequivalence Studies Submitted in NDAs ...
https://www.fda.gov/files/drugs/published/Bioavailability-and-Bioequivalence-Studies-Submitted-in-NDAs-or-INDs-%E2%80%94-General-Considerations.pdf
E. ORALLY ADMINISTERED DRUGS INTENDED FOR LOCAL ACTION. ... 65 FDA's 2002 guidance for industry on Food-Effect Bioavailability and Fed Bioequivalence.
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67 Ectopic Fat Depots and Cardiovascular Disease - AHA Journals
https://www.ahajournals.org/doi/full/10.1161/circulationaha.111.077602
These findings suggest that the systemic effects of obesity appear to outweigh any local effect of pericardial fat in the case of left ...
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68 Chemotherapy Side Effects | American Cancer Society
https://www.cancer.org/treatment/treatments-and-side-effects/treatment-types/chemotherapy/chemotherapy-side-effects.html
Some chemo drugs can damage cells in the heart, kidneys, bladder, lungs, and nervous system. Sometimes, you can take medicines with the chemo to ...
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69 Everything You Need to Know About Corticosteroids - Healthline
https://www.healthline.com/health/corticosteroids-what-are-they
Corticosteroids: Uses, Types, Side Effects and Interactions ... Systemic steroids move through the blood to assist more parts of the body.
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70 The primary difference between local and systemic toxicity has ...
https://homework.study.com/explanation/the-primary-difference-between-local-and-systemic-toxicity-has-to-do-with-which-of-the-following-a-duration-of-exposure-b-concentration-of-toxicant-c-site-of-toxicity-d-bio-transformation-e-bio-availability-of-toxicant.html
Local toxicity is restricted to a particular area, whereas systemic exposure can potentially move to other parts of the body and impart toxic responses to ...
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71 Lidocaine (Injection Route) Side Effects - Mayo Clinic
https://www.mayoclinic.org/drugs-supplements/lidocaine-injection-route/side-effects/drg-20452273?p=1
Lidocaine is a local anesthetic. It prevents pain by blocking the signals at the nerve endings in the skin. This medicine does not cause unconsciousness as ...
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72 Assessment of the Local Effects of Ketamine Requires ...
https://www.joms.org/article/S0278-2391(09)01504-3/fulltext
These results led us to believe that, beside the local analgesic effect, the systemic analgesic effects of ketamine may also be important in dental surgery.
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73 Appendix A to § 1910.1200 - Health Hazard Criteria (Mandatory)
https://www.osha.gov/laws-regs/regulations/standardnumber/1910/1910.1200AppA
A.0.2.5 The effect of a chemical on biological systems is influenced, ... order to avoid testing for local effects on eyes with skin corrosive substances.
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74 Risks of systemic effects after dermal exposure for workers
https://www.rivm.nl/bibliotheek/rapporten/320041002.pdf
systemic adverse health effects. Local effects take place at the point or area of contact, the site may be skin, the respiratory tract, ...
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75 Homelessness and Racial Disparities
https://endhomelessness.org/homelessness-in-america/what-causes-homelessness/inequality/
The disproportionality in homelessness is a by-product of systemic inequity: the lingering effects of racism continue to perpetuate disparities in critical ...
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76 asphyxiant - Worker Right-To-Know
http://www.chemicalspill.org/WorkerRTK/effects1.html
EFFECTS CHEMICALS HAVE ON THE BODY. ROUTES OF EXPOSURE: Inhalation - local effect - lung systemic effect- blood, target organ. Ingestion - local effect - GI ...
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77 Burns Overview - Physiopedia
https://www.physio-pedia.com/Burns_Overview
Systemic absorption of some chemicals is life-threatening, and local ... a severe burn injury has an effect on different organs and systems in the body.
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78 Systemic And Structural Racism: Definitions, Examples ...
https://www.healthaffairs.org/doi/10.1377/hlthaff.2021.01394
Systemic and structural racism are forms of racism that are ... It is far easier to mitigate the harmful effects of systemic racism while ...
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79 Local and systemic effects of microbiome‐derived metabolites
https://www.embopress.org/doi/10.15252/embr.202255664
Different end-products of microbial tryptophan metabolism can have either a beneficial or harmful impact (Agus et al, 2018; Paeslack et al, 2022) ...
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80 Xylocaine (Lidocaine): Uses, Dosage, Side Effects ... - RxList
https://www.rxlist.com/xylocaine-drug.htm
Xylocaine belongs to a class of drugs called Anesthetics, Topical; Local Anesthetics, Amides. It is not known if Xylocaine is safe and effective in children ...
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81 Guidance Document - Comparative Bioavailability Standards
https://www.canada.ca/en/health-canada/services/drugs-health-products/drug-products/applications-submissions/guidance-documents/bioavailability-bioequivalence/comparative-bioavailability-standards-formulations-used-systemic-effects.html
... Comparative Bioavailability Standards: Formulations Used for Systemic Effects. ... of products with drugs that are intended to act locally, for example, ...
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82 The Lungs as a Portal of Entry for Systemic Drug Delivery
https://www.atsjournals.org/doi/10.1513/pats.200409-049TA
Both molecules have the same therapeutic effect yet different absorption profiles. This shows that peptide absorption rates through the lung can ...
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83 Local and systemic effects caused by Crotalus durissus ...
https://www.scielo.br/j/rsbmt/a/r9kqXT5ppNVLSTFYdRR4JHJ/?lang=en
This study aims to compare the toxic effects (local and systemic) induced by the venom of Crotalus subspecies, C. durissus terrificus, C. durissus cascavella, ...
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84 Systemic effects and local effects in the gut - IOS Press
https://content.iospress.com/articles/biofactors/bio00368
by A Scalbert · 2000 · Cited by 149 —
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85 Long-Term Effects of Corticosteroids - GoodRx
https://www.goodrx.com/classes/corticosteroids/long-term-effects-corticosteroids
When a medication only has a local effect, it typically has less side effects and risks. Nasal corticosteroids usually only affect your nose and ...
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86 Systemic and local effects of lidocaine or mepivacaine when ...
https://beva.onlinelibrary.wiley.com/doi/abs/10.1111/evj.13236
Abstract Background Local anaesthetics are being combined clinically with amikacin in intravenous regional limb perfusion (IVRLP), ...
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87 Routes of Medication Administration
https://www.cfspharmacy.pharmacy/blog/post/routes-of-medication-administration
It only produces local effect in the eyes and there is minimum systemic absorption. Otic route: The drug is administered in the outer ear canal ...
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88 What is Food Insecurity? - Feeding America
https://www.feedingamerica.org/hunger-in-america/food-insecurity
Chronic health conditions or lack of access to healthcare; Systemic racism and racial discrimination. Effects of food insecurity. Food insecurity can have a ...
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89 Local Anesthetic Systemic Toxicity (LAST) Revisited
https://www.apsf.org/article/local-anesthetic-systemic-toxicity-last-revisited-a-paradigm-in-evolution/
Rapid cardiotonic effects of lipid emulsion infusion.* Crit Care Med. 2013;41: e156–162. Liu L, Jin Z, Cai X, et al. Comparative regimens of lipid ...
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90 The Difference Between Topical and Transdermal Medications
https://genscopharma.com/difference-topical-transdermal-medications/
This is due to the size and polarity of the drug molecule and the barrier effect of the skin. Many compounds are meant to remain on the skin surface ...
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91 Systemic Diseases vs Localized Diseases | Live Better
https://reverehealth.com/live-better/systemic-diseases-versus-localized-diseases/
What are some examples of the various local and systemic illnesses that doctors of internal medicine see on a daily basis?
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92 Systemic toxicology - EUPATI Toolbox
https://toolbox.eupati.eu/glossary/systemic-toxicology/
This refers to toxic effects caused as a result of absorption and distribution of a substance that affects the whole body rather than a specific (local) ...
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93 Recognition of Adverse and Nonadverse Effects in Toxicity ...
https://journals.sagepub.com/doi/pdf/10.1080/01926230252824725
only those differences judged to be effects are further evaluated in order to discriminate ... (eg, the route of exposure), local and systemic effects can.
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94 AstraZeneca and Pfizer: What are the side effects of Australia's ...
https://www1.racgp.org.au/newsgp/clinical/astrazeneca-and-pfizer-what-are-the-side-effects-f
Among recipients of the AstraZeneca and Pfizer vaccines, two in three report local side effects and one in four report systemic effects.
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95 Systemic Toxic Effects - Toxicology MSDT
https://www.toxmsdt.com/33-systemic-toxic-effects.html
Toxic effects are generally categorized according to the site of the toxic effect. In some cases, the effect may occur at only one site. This site is termed the ...
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